• Title/Summary/Keyword: songorine

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Diterpene Alkaloids from Kyong-Po Buja (Processed Aconitium carmichaeli) (경포부자의 다이테르펜 알칼로이드 성분)

  • Choi, Sang-Zin;Kwon, Hak-Cheol;Min, Yong-Deak;Lee, Sung-Ok;Kim, Kyung-Ran;Choi, Sang-Un;Son, Kun-Ho;Kang, Sam-Sik;Lee, Kang-Ro
    • Korean Journal of Pharmacognosy
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    • v.33 no.3 s.130
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    • pp.187-190
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    • 2002
  • Three diterpene alkaloids, songorine (1), neoline (2), N-deethylneoline (3), were isolated from Kyong-Po Buja (Processed Aconitium carmichaeli, Ranunculaceae) which was used as Chinese traditional medicine with analgesic, anti-inflammatory and cardiotonic activity. Their structures were established by chemical and spectroscopic methods.

Isolation and Oxidation Characteristics of Alkaloids of Aconitum volubile (가는줄돌쩌기 알칼로이드 성분의 분리 및 산화적 특성)

  • Heo, Kyong-Hee;Lee, Chung-Kyu
    • Korean Journal of Pharmacognosy
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    • v.39 no.2
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    • pp.127-134
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    • 2008
  • From the under ground part of Aconitum volubile Pall. (Ranunculaceae),seven nor- or di-terpenoid alkaloids were isolated and identified by NMR spectra and mass spectrum. The alkaloids were three $C_{19}$-norditerpenoid alkaloids such as isotalatizidine, altaconitine and vilmorrianine A, and four $C_{20}$-diterpenoid alkaloids such as 12-epidehydronapelline, 12-epinapelline, songoramine and songorine. Some of the isolated diterpenoid alkaloids were subjected to oxidation reaction with active $MnO_2$ and oxoammonium salt. The results were C-12 oxidation(ketone formation) and N-dealkylation in veatchin-type and decomposition to non-alkaloidal compounds in atisine-type ajaconine.