• Clinical and Experimental Pediatrics
• /
• v.64 no.6
• /
• pp.251-259
• /
• 2021

Psychogenic nonepileptic seizures (PNES) is a neuropsychiatric condition that causes a transient alteration of consciousness and loss of self-control. PNES, which occur in vulnerable individuals who often have experienced trauma and are precipitated by overwhelming circumstances, are a body's expression of a distressed mind, a cry for help. PNES are misunderstood, mistreated, under-recognized, and underdiagnosed. The mind-body dichotomy, an artificial divide between physical and mental health and brain disorders into neurology and psychiatry, contributes to undue delays in the diagnosis and treatment of PNES. One of the major barriers in the effective diagnosis and treatment of PNES is the dissonance caused by different illness perceptions between patients and providers. While patients are bewildered by their experiences of disabling attacks beyond their control or comprehension, providers consider PNES trivial because they are not epileptic seizures and are caused by psychological stress. The belief that patients with PNES are feigning or controlling their symptoms leads to negative attitudes of healthcare providers, which in turn lead to a failure to provide the support and respect that patients with PNES so desperately need and deserve. A biopsychosocial perspective and better understanding of the neurobiology of PNES may help bridge this great divide between brain and behavior and improve our interaction with patients, thereby improving prognosis. Knowledge of dysregulated stress hormones, autonomic nervous system dysfunction, and altered brain connectivity in PNES will better prepare providers to communicate with patients how intangible emotional stressors could cause tangible involuntary movements and altered awareness.

• Korean Journal of Biological Psychiatry
• /
• v.13 no.4
• /
• pp.234-243
• /
• 2006

Objectives : Several factors, such as biological markers, clinical correlates, and course of the depressive disorders with psychotic symptoms differ from those without psychotic symptoms. Therefore, specification of a treatment algorithm for depressive disorder with psychotic symptoms is legitimated. This article provides a systematic review of somatic treatments for depressive disorder with psychotic symptoms. Methods : According to the search strategy of the Clinical Research Center for Depression of Korean Health 21 R & D Project, first, PubMed and EMBASE were searched using terms with regard to the treatment of depressive disorders with psychotic symptoms(until July 2006). Reference lists of related reviews and studies were searched. In addition, relevant practice guidelines were searched using PubMed. All identified clinical literatures were reviewed and summarized in a narrative manner. Results : Treatment options, such as a combination of an antidepressant and an antipsychotic versus an antidepressant or an antipsychotic alone are summarized. In addition, issues regarding the electroconvulsive therapy( ECT), combination therapy, and maintenance treatment are discussed. Conclusion : In former times, the combination of an antidepressant and an antipsychotic or ECT were recommended as the first line treatment for depressive disorder with psychotic symptoms. Recently, however, there was a suggestion that there was no conclusive evidence that the combination of an antidepressant and an antipsychotic drug is more effective than an antidepressant alone. More evidence regarding the pharmacological treatment for depressive disorder with psychotic symptoms is needed.

• Korean Journal of Adult Nursing
• /
• v.22 no.6
• /
• pp.634-643
• /
• 2010

Purpose: The purpose of this study was to identify the reported factors influencing fatigue of middle aged women. Methods: Two hundred seven middle aged women between 40 and 59 years of age were recruited from five areas in Korea from March 1, 2010, to April 20, 2010. Data were collected by self-reported questionnaires. Data analysis was done using SPSS/WIN 15.0 program for descriptive statistics, Pearson correlation coefficients and stepwise multiple regression. Results: The average score of fatigue was $2.34{\pm}0.40$. There were significant differences in reported fatigue according to economic status and health status. The reported fatigue was significantly correlated with somatic attribution, psychological attribution, normalizing attribution, depression, marital adjustment, stress, and social support. The major factors that affect fatigue in middle aged women were stress, depression, and normalizing attribution, which explained 32.3% of fatigue. Conclusion: The findings can reduce the fatigue by controlling stress and depression. Additionally, this study can understand the attribution of fatigue in middle aged women. More studies are needed to identify other variables that influence on the fatigue of middle aged women.

• Journal of the Korean Home Economics Association
• /
• v.37 no.10
• /
• pp.107-122
• /
• 1999

Based on the theoretical framework of the Double ABCX model of family stress and adaptation, this study was to analysis the causal relationships of stressors (psychological sexual, and physical wife abuse), personal resources (self-efficacy and self-esteem) and social support(emotional and informational support), appraisal(positive appraisal and downward comparisons) with adaptation (psychological well-being and somatic symptoms). Self-administered questionnaire method was used to collect data from 264 wives residing in Chonbuk-do and Kyonggi-do area. The causal model was tested and modified by the maximum likelihood method using UISREL 7 program. Results showed that wife abuse had effect on adaptation indirectly through the latent variables of personal resource and appraisal, which influenced the adaptation directly. In addition, social support indirectly affect the adaptation through personal resource and appraisal. It was also found that all these variables explained 27.6% of the total variance of wives'adaptation, and that personal resources was the most powerful variable in predicting the adaptation of the wives.

• CELLMED
• /
• v.1 no.1
• /
• pp.5.1-5.3
• /
• 2011

Molecular events that cause tumor formation enhance a number of HOX genes, called switch genes, coding for RNApolymeraseII transcription factors. Thus, in tumor cells, RNApolymeraseII is more active than in other somatic cells. Amanita phalloides contains amanitin which inhibits RNApolymeraseII. Partial inhibition with amanitin influences tumor cell - but not normal cell - activity. To widen the treatment spectrum, dilutions of Amanita phalloides, containing amanitin, are applied to a patient with mammary duct cancer. For monitoring tumormarkers, different doses of amanitin are applied. The former duplication time of tumor growth represented three months; however within a period of 18 months the patient can be stabilized without further growth of the tumor. There are also no severe symptoms, no liver damage and no continuous erythrocyte deprivation. This new principle of tumor therapy shows high potential to provide a medical treatment.

• Korean Security Journal
• /
• no.8
• /
• pp.309-336
• /
• 2004

Approximately equivalent to character disorder or character neuroses or behavioral reaction. For a discussion of the term as used currently, in the 1968 revision of psychiatric nomenclature(DSM-II). In DSM-I(1952 nomenclature), this term referred to those cases in which the personality, in its struggle for adjustment to internal and external stresses, utilized primarily a pattern of action or behavior rather than symptoms in the mental, somatic or emotional spheres. There is minimal subjective anxiety and little or no sense of distress. As thus defined, there are three main groups of personality disorder, personality pattern disturbance, personality trait disturbance and sociopathic, personality disturbance. Morton Prince asks whether a subconscious process can perform the same function as are ordinarily performed by conscious intelligence that is to say memory, perception, reasoning, imagination, volition, affectivity, etc? He cites clinical material at great length, concluding that the quality of the functions performed they frequently exhibit, that which is characteristic of intelligence.

• Research in Community and Public Health Nursing
• /
• v.18 no.1
• /
• pp.136-145
• /
• 2007

Purpose: This study was attempted to illuminate danger signals through an extensive analysis of factors influencing adolescents' illicit drug use. On this basis, it built predictive factors of adolescents' illicit drug use. Method: A questionnaire was distributed to 1,238 subjects living in Seoul, and of them 1,082 answers were analyzed using the SAS 8.2 program. Also logistic regression analysis was conducted based on the stepwise selection method for constructing the predictive factors. Results: The findings of this study are as follows. Individual-related factors were psycho-somatic symptoms, self-esteem, fortune delinquent experience, and sexual-violence delinquent experience. Home-related factors were insincerity, threatening and the assessment of the parent (rearer)-adolescent communication type. Society-related factors were affection of friends and friends' attitude toward delinquency. Conclusion: These findings of this study suggest that a broad intervention program should be provided to nurture wholesome youth culture related to illicit drug use. It is also recommended that a variety of individual, home and society-related programs should be developed for drug users.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.27 no.2
• /
• pp.84-86
• /
• 2016

Globus pharyngeus or globus sensation is the painless sensation of a lump in the throat and may be described as a foreign body sensation, a tightening or choking feeling. It is often associated with persistent clearing of the throat, chronic cough, hoarseness, and catarrh. Its etiology remains unclear ; however, laryngopharyngeal reflux may play a role in a subset of patients. Psychogenic problems have often been thought to cause or trigger the globus sensation. Personality studies have found higher levels of alexithymia, neuroticism, and psychological distress (including anxiety, low mood, and somatic concerns) and lower levels of extraversion in patients presenting with globus. Globus patients with laryngopharyngeal reflux exhibited weaker psychological symptoms than non- laryngopharyngeal reflux globus patients, and globus patients who did not respond to proton pump inhibitor had significantly higher anxiety scores. In cases with negative clinical investigations and consistent globus symptom, other treatment strategies, including speech therapy, antidepressants, and cognitive-behavioral therapy, should be considered.

• Journal of Fisheries and Marine Sciences Education
• /
• v.25 no.1
• /
• pp.87-101
• /
• 2013

The purpose of this study was to analyze differences in psychological characteristics according to cell phone dependency and use purpose in cell phone users of adolescences. Psychological characteristics of adolescents were consisted of attention aggression, somatic symptoms, social withdrawal, depression variables. The subjects were 2,158 cell phone owned second graders of middle school. A data of the Korean Child-Youth Panel Survey(KCYPS) was employed for the this study. Dependency and use purpose of cell phone were classified by cluster analysis into four groups with similar characteristics : 'high dependency-multipurpose', 'low dependency-social', 'low dependency-unsocial' 'middle dependency-peer interaction' groups. Major findings were that: the group differences in psychological characteristics were statistically significant. The 'low dependency-social' group showed highest on adjustments, and the other groups were maladaptive. Finally, implications for future research were discussed.

• Investigative Magnetic Resonance Imaging
• /
• v.23 no.4
• /
• pp.395-400
• /
• 2019

Acromegaly is a rare endocrine disorder caused by excessive secretion of the growth hormone. There is a wide range of clinical manifestations from somatic symptoms to respiratory or cardiac failure. Among them, cardiovascular involvement is a leading cause of morbidity and mortality. There are relatively few cases reporting cardiac magnetic resonance imaging (CMR) findings of cardiomyopathy in patients with acromegaly. Thus, we report a case of acromegaly showing dilated cardiomyopathy focusing on the findings of CMR.