• 한국식품과학회지
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• 제5권1호
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• pp.1-5
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• 1973

Wet gluten 에 salt 및 소량의 산(酸)을 가하여 상압하(常壓下)에서 $6^{\circ}C$로 열풍건조하여 vital gluten 을 제조하였다. 이때 salt 및 산(酸)은 gluten의 점착성을 저하시켜 표면적을 크게하고 열내성(熱耐性)이 생기게 하여 건조를 쉽게 하였다. 1) Salt 농도는 높을수록 glulen의 건조가 용이하나, quality 는 저하되었다 salt 는 $5{\sim}10%$가 좋을 것같다. 2) Salt 외에 HCI을 0.12%첨가한 결과 건조 시간은 거의 반으로 단축되었고, glulen의 질(質)은 저하되지 않았다. 3) 산(酸)은 hydrochloric, acetic, phosphoric, lactic acid 중(中)에서 hydrochloric acid 건조 시간을 가장 적게 하였으며 질(質)은 별 차이 없으므로 hydrochloric acid 첨가가 가장 좋았다.

• 한국미생물·생명공학회지
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• 제2권2호
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• pp.111-117
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• 1974

\circled1 분리선별한 Naringinase 생산균인 S-1 SP, 은 Aspergillus niger 이었다. \circled2 Naringinase중 정제된 naringin 용해화 효소를 aceton과 ammonium sulfate에 의해 결정화하였다. \circled3 Naringin용해화 효소와 naringenin 생성효소가 DEAE-sephadex A-50 column chromatography에 의해 분리되었다. \circled4 Naringin 용해화 효소에 의해 분해된 물질이 Thin layer chromatography에의해 확인되었으며 이물질은 ethylacetate 추출법에 의해 naringin분리 정량이 가능하였다. \circled5 Crude naringinase를 여름밀감 과즙과 병조림 탈고미에 이용하여 ethylacetate 추출법에 의해 naringin을 정량하고 식미시험 결과와 비교하였다. 본 연구에 많은 조언을 해 주신 경북대학교 농화학과 서정훈 박사님께 감사를 드립니다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1996년도 춘계학술대회
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• pp.284-284
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• 1996

Titrated Extract of Centella asiatica (TECA) is a poorly water-soluble extract from the Centella asiatica. Despite excellent wound preparation causes pain due to a low aqueous solubility and high hypertonicity and therefore, the patient's compliance of this drug is low. The objective of this study is to design a formulation of TECA with an improved therapeutic applicability via an adequate solubilization. A mixture of propylene glycol and ethoxylated hydrogenated caster oil achieved an acceptable solubilization of TECA (i.e. 10%) via a formulation of micelle. A preparation of extemporaneous TECA micelle was achieved by a dilution of the original micellar formulation with either water or saline. An estimated distribution of particle size was between 15.9 and 32.6 ㎜. The osmotic pressure of the formulation was found to be much lower than that found In a commercially available injectable (i.e. Madecassole). The erthrocytic hemolysis of micellar solution was lower than that with the conventional dosage form, consistent with the osmotic pressure data. Pain score after an injection of the micellar solution was assessed by the hind-paw writhing test using ICR mice and compared with that found with the conventional injectable. The data indicated that the injection of the micellar solution was a significantly less painful. These results indicated that a micellar solubilization, followed by an extemporaneous dilution, is a novel formulation of TECA with an improved therapeutic applicability.

• 융복합기술연구소 논문집
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• 제3권1호
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• pp.15-18
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• 2013

The next generation alternative fuel of diesel, DME (Dimethyl Ether) discharges particulate matter hardly due to chemical structural as oxygen-fuel so it has the eco-friendly property. Despite these advantages, the DME has the technical difficulties to apply to the diesel engine because of a low calorific value, viscosity and compressibility effects. From this point of view, we performed experimental studies on improved reliability of DME common-rail vehicle and lubricity enhancement of DME fuel for empirical distribution of eco-friendly DME fuel. Also we analyzed solubility of lubrication enhancer according to a drop in temperature, try to secure reliability about core parts of DME vehicle by applying lubrication enhancer in the DME common-rail vehicle.

• 한국지하수토양환경학회지:지하수토양환경
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• 제21권5호
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• pp.1-7
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• 2016

The removal of non-aqueous phase liquids (NAPLs) from groundwater using pure water, via pump and treat, is quite ineffective due to their low solubility and hydrophobicity. Therefore, the objectives of pilot tests were to select potentially suitable surfactants that solubilize tetrachloroethylene (PCE) and trichloroethylene (TCE) present as contaminants and to evaluate the optimal range of process parameters that can increase the removal efficiency in surfactant-enhanced soil flushing (SESF). Used experimental method for surfactant selection was batch experiments. The surfactant solution parameters for SESF pilot tests were surfactant solution concentration, surfactant solution pH, and the flow rate of surfactant solution in the SESF pilot system. Based on the batch experiments for surfactant selection, DOSL (an anionic surfactant) was selected as a suitable surfactant that solubilizes PCE and TCE present as contaminants. The highest recovery (95%) of the contaminants was obtained using a DOSL surfactant in the batch experiments. The pilot test results revealed that the optimum conditions were achieved with a surfactant solution concentration of 4% (v/v), a surfactant solution pH of 7.5, and a flow rate of 30 L/min of surfactant solution (Lee and Woo, 2015). The maximum removal of contaminants (89%) was obtained when optimum conditions were simultaneously met in pilot-scale SESF operations. These results confirm the viability of SESF for treating PCE and TCE-contaminated groundwater.

• 한국환경농학회지
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• 제12권1호
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• pp.69-80
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• 1993

Environmental hazards of a chemical could be assessed by two different approaches : toxicity test and assessment of exposure potentials to human and environmental organisms. For the prediction of environmental fate of chemicals three available computer programs were compared each other and were verified. The results obtained by using these computer programs, PCHEM, EXAMS, and E4CHEM were summarized as follows. The estimated octanol/water partition coefficients by PCHEM were similar to the experimental values in the literature. But the other factors, water solubility and vapor pressure were different from the data in the literature. The simulation results of selected compounds by EXAMS showed similar tendency to the literature results of model field environment. Therefore, this computer program could be utilized to predict the environmental fate of chemicals. E4CHEM program is very simple and this program could predict the ultimate environmental fate of stable chemicals by input of two or three parameters. However, the validity should further be verified in the future field study using more compounds. It is suggested that these approaches could be fully utilized by understanding their limitations to predict the environmental fate of new chemicals under development, to screen the potential environmental pollutants among chemicals already-in use, and to devise measures to minimize the hazards to the environment.

• Journal of Nutrition and Health
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• 제14권1호
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• pp.26-33
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• 1981

Crocin was extracted from Gardenia fructus in order to manufacture a natural food dye. In the extraction and purification process methanol and ethanol were used as the most Suitable solvent selected in preliminary test and 9.28%g/100g of Cretin product in 99.89% of purity was acquired. The lethal dose of Cretin administered in mouse by intra peridoneal was 5.36g/kg which is much lower toxic than any other. The toxic dose which caused diarrhoea in rat was 2.55g/kg and maximum no effect level was found to be 272mg/kg. From the $1%{\sim}2.5%$ content of Crocin in rat diet reduction of body weight appeared and GTP and GOT (Transaminase) value in creased significantly. Crocin showed a good properties of tolerating acid, alkali, sunlight, reductant, oxidant, and salt compared with tar dyes. The range from 100 ppm to 500ppm bring out bright $yellow{\sim}orange$ color, the most effective color, with a good solubility in water-slightly in oil. The acceptable daily intake of crocin was calculated as 2.72mg/kg based on maximum no effect dose (2% additive dose).

• 접착 및 계면
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• 제4권2호
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• pp.1-9
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• 2003

Epoxy-amine liquid prepolymers are extensively applied onto metallic substrates and cured to obtain painted materials or bonded joint structures. Overall performances of such systems depend on the created interphase between the organic layer and the substrate. When epoxy-amine liquid mixtures are applied onto more or less hydrated metallic oxide layer, concomitant amine chemical sorption and hydroxide dissolution appear lending to the chelate formation. As soon as the chelate concentration is higher than the solubility product, these species crystallize as sharp needles. Moreover, intrinsic and thermal residual stresses are developed within painted or bonded systems. When residual stresses are higher than the organic layer/substrate adhesion, buckling, blistering, debonding may occur leading to a catastrophic drop of system performances. Practical adhesion can be evaluated with either ultimate parameters (Fmax or Dmax) or the critical strain energy release rate, using the three point flexure test (ISO 14679-1997). We observe that, for the same system, the ultimate load decreases while residual stresses increase when the liquid/solid time increases. Ultimate loads and residual stresses depend on the metallic surface treatment. For these systems, the critical strain energy release rate which takes into account the residual stress profile and the Young's modulus gradient remains quite constant whatever the metallic surface treatment was. These variations will be discussed and correlate to the formation mechanisms of the interphase.

• Journal of Yeungnam Medical Science
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• 제11권1호
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• pp.30-34
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• 1994

염산 lidocaine의 피하 주입시 발생되는 고통을 감소시키기 위하여 8.4% sodium bicarbonate로 중화시켜 사용해 보았다. 지원자를 대상으로한 실험군의 100%에서 예상된 효과를 얻을 수 있었다.

• 폴리머
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• 제24권1호
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• pp.23-28
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• 2000

Solvent 용접에 따른 무정형 고분자 폴리스티렌/폴리스티렌 계면의 접착강도의 변화를 butt joint실험을 통하여 살펴보았다. 폴리스티렌과 용해도 상수가 유사한 용매를 계면에 코팅함으로써 계면 분자쇄의 유동성 증가와 계면의 거침정도의 변화에 따른 접촉표면의 증가로 인하여 접착 강도가 증가함을 확인하였다. 사용용매의 비등점이 접착온도보다 높은 경우, 접착강도의 증가는 용매에 의한 분자쇄의 유동성 증가에 기인되는 반면 용매의 비등점이 접착온도에 비해 낮을 경우 접착강도의 증가는 용매에 의한 접촉표면의 증가에 의존함을 알 수 있었다. 접착온도가 높을수록, 접착시간이 길어질수록 접착강도는 증가되며, 사용용매가 접착강도에 미치는 영향은 감소함을 알 수 있었다.