• Title/Summary/Keyword: smg-2

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Guidelines for Transrectal Ultrasonography-Guided Prostate Biopsy: Korean Society of Urogenital Radiology Consensus Statement for Patient Preparation, Standard Technique, and Biopsy-Related Pain Management

  • Myoung Seok Lee;Min Hoan Moon;Chan Kyo Kim;Sung Yoon Park;Moon Hyung Choi;Sung Il Jung
    • Korean Journal of Radiology
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    • v.21 no.4
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    • pp.422-430
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    • 2020
  • The Korean Society of Urogenital Radiology (KSUR) aimed to present a consensus statement for patient preparation, standard technique, and pain management in relation to transrectal ultrasound-guided prostate biopsy (TRUS-Bx) to reduce the variability in TRUS-Bx methodologies and suggest a nationwide guideline. The KSUR guideline development subcommittee constructed questionnaires assessing prebiopsy anticoagulation, the cleansing enema, antimicrobial prophylaxis, local anesthesia methods such as periprostatic neurovascular bundle block (PNB) or intrarectal lidocaine gel application (IRLA), opioid usage, and the number of biopsy cores and length and diameter of the biopsy needle. The survey was conducted using an Internet-based platform, and responses were solicited from the 90 members registered on the KSUR mailing list as of 2018. A comprehensive search of relevant literature from Medline database was conducted. The strength of each recommendation was graded on the basis of the level of evidence. Among the 90 registered members, 29 doctors (32.2%) responded to this online survey. Most KSUR members stopped anticoagulants (100%) and antiplatelets (76%) one week before the procedure. All respondents performed a cleansing enema before TRUS-Bx. Approximately 86% of respondents administered prophylactic antibiotics before TRUS-Bx. The most frequently used antibiotics were third-generation cephalosporins. PNB was the most widely used pain control method, followed by a combination of PNB plus IRLA. Opioids were rarely used (6.8%), and they were used only as an adjunctive pain management approach during TRUS-Bx. The KSUR members mainly chose the 12-core biopsy method (89.7%) and 18G 16-mm or 22-mm (96.5%) needles. The KSUR recommends the 12-core biopsy scheme with PNB with or without IRLA as the standard protocol for TRUS-Bx. Anticoagulants and antiplatelet agents should be discontinued at least 5 days prior to the procedure, and antibiotic prophylaxis is highly recommended to prevent infectious complications. Glycerin cleansing enemas and administration of opioid analogues before the procedure could be helpful in some situations. The choice of biopsy needle is dependent on the practitioners' situation and preferences.

Effect of Platelet-rich Plasma (PRP) on Regeneration of Rat Sciatic Nerve in a Silicone Chamber

  • Minn, Kyung-Won;Jeong, Eui-Cheol;Chang, Hak;Kwon, Sung-Tack;Kim, Suk-Wha;Baek, Rong-Min
    • Archives of Plastic Surgery
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    • v.37 no.2
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    • pp.105-109
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    • 2010
  • Purpose: The purpose of this study is to determine the effect of platelet-rich plasma (PRP) on rat sciatic nerve regeneration in a 10 mm silicone chamber. Methods: A total of 6 inbred Lewis rats were used in this study. Bilateral sciatic neurectomy was performed on each rat. On one side, silicone chambers containing PRP solutions were implanted; on the contralateral side, the chambers without PRP were implanted as a control. In 12 weeks post-implantation, chambers were retrieved and both gastrocnemius muscles were excised. Nerves biopsy samples were examined under a light microscope after Masson trichrome staining. Results: Cross sections of the midpoints of PRP treated nerves were significantly larger and appeared more mature than those of controls. Conclusion: Based on morphological evidence, PRP has a positive effect on neural regeneration, and it may therefore be useful for treating peripheral nerve injuries.

A study on strategical statistical multiplexing of VBR MPEG bit streams and QoS based multiplexing gains (가변비트율 MPEG-2 비트열의 합성과 QoS를 고려한 다중화 이득에 관한 연구)

  • 장승기;서덕영;경문현;박섭형;정재일
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.21 no.11
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    • pp.2836-2849
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    • 1996
  • Over ATM network, variable bit rate(or VBR) traffic is allowed. Control of VBR traffic is allowed. Control of VBR traffic becomes difficult if it is bursty. VBR video traffic becomes so much bursty during intra frame period that much cell loss would occur when satistical multiplexed in ATM swich. To aviod cellloss, extra communication resources should be allocated, which reduces the capability of an ATM channel. In this paper, we propose two methods which enable a channel limited in resources to serve more VBR MPEG video bit streams. Firstly, we could redue the bitrate fluction of a statiscally multiplexed bundle of VBR video bit streams by reducing the number of intra frames overlapped at the same frame period. This method can be used in ATM switch which controls multiple video sources. Secondary, in two layer enoding, statistical multiplexing gains can be icreased by letting peak bit rate durations of both layers not be overlapped. This results in more smooth traffic. The performance of proposed methods are demonstrated by a proposed calculation method of statistical multiplexing gains(or SMGs.) The proposed SMG is based on both delay and cell loss QoS requirements at the same time.

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Climate Change Adaptation Strategy by Multipurpose, Proactive Rainwater Management and Case Studies in Korea (다목적이고 적극적인 빗물관리에 의한 기후변화 적응방안과 국내 사례)

  • Han, Mooyoung;Mun, Jungsoo;Kim, Tschungil
    • Journal of Korean Society of Water and Wastewater
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    • v.23 no.2
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    • pp.223-230
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    • 2009
  • Most urban water management systems are becoming vulnerable to flooding and drought due to the climate change (CC), urbanization and energy shortage. Despite of poor water management circumstances caused by extremely uneven annual rainfall and hilly terrain, traditionally we have made a sound and sustainable life based on our own philosophy and technologies which copes with our rigid environment. In this study a new paradigm of rainwater management is suggested and multipurpose and creative rainwater harvesting and management (RWHM) systems are introduced providing several case studies such as rainfall storage drainage (RSD) system, rainwater infiltration facilities and star city RWHM system. This new RWHM paradigm leads Seoul Metropolitan Government (SMG) in the Republic of Korea to change regulations and politics for the integrated RWHM. Finally, RWHM is expected to improve the safety, efficiency, energy consumption of urban water infrastructure, to reduce urban heat island phenomenon and, furthermore, to contribute in finding solutions for worldwide water issues and to adapt CC.

Multi-wavelength Extragalactic Studies in the AKARI Deep Field - South

  • Jeong, Woong-Seob;Kim, Minjin;Ko, Jongwan;Park, Sung-Joon;Ko, Kyeongyeon;Jo, Youngsoo;Lee, Min Gyu;Seo, Hyun Jong;Kim, Taehyun;Pyo, Jeonghyun;Lee, Dongseob;Kim, Il-Joong
    • The Bulletin of The Korean Astronomical Society
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    • v.43 no.2
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    • pp.31.4-32
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    • 2018
  • The ADF-S (AKARI Deep Field - South) toward South Ecliptic Pole is one of the deep survey fields designed for the study of Cosmic Infrared Background (CIB). Owing to the easy accessibility with space missions and its low background brightness, the deep extragalactic survey was initiated by AKARI deep far-infrared observations and it will be performed by other future missions (e.g., Euclid, NISS, SPHEREx). The recent optical survey with KMTNet enabled us to identify the optical counterparts for dusty star-forming galaxies such as ULIRG, DOG, SMG. In addition, the NISS will perform the valuable spectro-photometric survey in the ADF-S. Those multi-wavelength data sets helps to trace the major galaxy population contributing to the CIB. Here, we introduce the extragalactic survey with the NISS and report the current status of the multi-wavelength extragalactic studies in the ADF-S.

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Common Sites, Etiology, and Solutions of Persistent Septal Deviation in Revision Septoplasty

  • Jin, Hong Ryul;Kim, Dae Woo;Jung, Hahn Jin
    • Clinical and Experimental Otorhinolaryngology
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    • v.11 no.4
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    • pp.288-292
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    • 2018
  • Objectives. To investigate the common causes of persistent septal deviation in revision septoplasty and to report the surgical techniques and results to correct them. Methods. A total of 100 consecutive patients (86 males) who had revision septoplasty due to persistent septal deviation from 2008 and 2014 were included in the study. Their mean age was 35.6 years and the mean follow-up duration was 9.1 months. Presenting symptoms, sites of persistent septal deviation, techniques used to correct the deviation, and surgical results were reviewed. Results. The mean interval between primary and revision surgery was 6.2 years. Forty-eight patients received revision septoplasty and 52 received revision septoplasty combined with rhinoplasty. Nasal obstruction was the most presenting symptom in almost all patients. The most common site of persistent septal deviation was middle septum (58%) followed by caudal septum (31%). Correcting techniques included further chondrotomy and excision of deviated portion in 76% and caudal batten graft in 39%. Rhinoscopic and endoscopic exams showed straight septum in 97% and 92 patients had subjective symptom improvement postoperatively. Conclusion. Middle septum and caudal septum were common sites of persistent deviation. Proper chondrotomy with excision of deviated middle septum and correction of the caudal deviation with batten graft are key maneuvers to treat persistent deviation.

Combination of oxaliplatin and β-carotene suppresses colorectal cancer by regulating cell cycle, apoptosis, and cancer stemness in vitro

  • Junghyeun Lee;Seung Chul Heo;Yuri Kim
    • Nutrition Research and Practice
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    • v.18 no.1
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    • pp.62-77
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    • 2024
  • BACKGROUND/OBJECTIVES: Colorectal cancer (CRC) is the third most common cancer worldwide with a high recurrence rate. Oxaliplatin (OXA) resistance is one of the major reasons hindering CRC therapy. β-Carotene (BC) is a provitamin A and is known to have antioxidant and anticancer effects. However, the combined effect of OXA and BC has not been investigated. Therefore, this study investigated the anticancer effects and mechanism of the combination of OXA and BC on CRC. MATERIALS/METHODS: In the present study, the effects of the combination of OXA and BC on cell viability, cell cycle arrest, and cancer stemness were investigated using HCT116, HT29, OXA-resistant cells, and human CRC organoids. RESULTS: The combination of OXA and BC enhanced apoptosis, G2/M phase cell cycle arrest, and inhibited cancer cell survival in human CRC resistant cells and CRC organoids without toxicity in normal organoids. Cancer stem cell marker expression and self-replicating capacity were suppressed by combined treatment with OXA and BC. Moreover, this combined treatment upregulated apoptosis and the stem cell-related JAK/STAT signaling pathway. CONCLUSIONS: Our results suggest a novel potential role of BC in reducing resistance to OXA, thereby enhances the anticancer effects of OXA. This enhancement is achieved through the regulation of cell cycle, apoptosis, and stemness in CRC.

A RETROSPECTIVE STUDY ON INCIDENCE OF C-SHAPED CANALS IN MANDIBULAR SECOND MOLARS (하악 제2대구치의 C형 근관 발현빈도에 관한 후향적 연구)

  • Kim, Hee-Sun
    • Restorative Dentistry and Endodontics
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    • v.34 no.4
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    • pp.346-349
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    • 2009
  • Mandibular second molars have many variations in canal configuration. Technical modifications in cleaning, shaping and obturation are required. The purpose of this study was to investigate the root canal anatomy of mandibular second molars. 86 teeth of 85 patients were accessed and evaluated with taking radiographs for working length determination. 27 teeth(31.4%) had C-shaped canals, 43 teeth(50%) had 3 canals, 11 teeth(12.7%) had 4 canals, 5 teeth(5.8%) had 2 canals. Incidence of C-shaped canal was 31.7% in male and 31.1% in female. 30.9% of left mandibular second molar and 31.8% of right mandibular second molar showed C-shaped canals.

ETSI BRAN(Broadband Radio Access Network)의 무선 ATM 및 광대역 무선 액세스 네트워크 표준화 및 기술동향

  • 이우용;김용진;강충구
    • Information and Communications Magazine
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    • v.15 no.11
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    • pp.124-142
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    • 1998
  • ETSI BRAN (Broadband Radio Access Network)는 고속 무선 LAN 또는 고정 광대역 무선액세스 네트워크에서의 무선 접촉 계층과 ATM 및 IP(Internet Protocol) 코어 네트워크와의 연동을 위한 일부 기능을 표준화하기 위한 과제이다. 특히, BRAN의 HIPERLAN type-2(HIPERLAN/2)의 경우에는 과제의 범위는 무선 접속면, 무선 부시스템에서의 서비스 인터페이스, 서비스 구현에서 요구되는 연동 및 각종 지원 기능을 표준화하며, 무선 접속면의 경우에는 다수 벤더간의 상호 호환성을 제공할 수 있는 인터페이스를 구현하는 것이다. HIPERLAN/2의 기술 규격은 코어 네트워크와 독립적인 물리계층 및 데이터 링크 제어 (DATA Link Control: DLC) 계층과 서로 상이한 코어 네트워크와의 연동을 위한 네트워크 수렴 부계층을 다루게 될 것이며, 초기 단계에서는 ATM과 IP 코어 네트워크와의 연동 기능을 제시하게 될 것이다. 따라서 HIPERLAN/2기반의 시스템 규격을 제시하기 위해서는 네트워크 계층 및 기타 상위 계층에 대한 규격이 요규되며, 이는 ATM Forum에서의 무선 ATM 신호 방식 규격, IETF(Internet Engineering Task Force)의 IP규격, 그리고 ETSI의 SMG (Special Mobile Group) 프로젝트에서 표준화되고 있는 UMTS (Universal Mobile Telecommunication Service) 규격 등과 접목될 것이다. 결과적으로 무선 ATM 관점에서는 완전한 시스템 규격 작성은 ETSI BRAN과 ATM Forum에서 무선 접속 규격과 이동성 관리 및 신호 방식으로 각각 이원화되어 진행되고 있다. 현재 물리 계층에서의 전송 방식은 OFDM(Orthogonal Frequency Division Multiplexing)으로 확정되었으며, DLC 계층에서는 고정 길이의 TDD (Time Division Duplexing) TDMA 프레임 구조를 기반으로 AP (Access Point)에 의해 동적으로 상향 링크 자원을 예약 할당하는 매체 접근 제어 (Medium Access Control: MAC) 프로토콜이 고려되고 있다. 이와 같은 DLC 계층에서는 기본적으로 짧은 길이의 패킷을 통해 다양한 대역폭의 멀티미디어 트래픽을 효율적으로 수용하면서 ATM 네트워크뿐만 아니라 향후 IP 네트워크에서 요구하는 각 서비스별 QoS (Quality of Service)를 개별적으로 보장할 수 있는 기능을 구현하고자 한다. 향후 이 부문에 대한 표준화가 본격적으로 진행될 것으로 예상되며 HIPERLAN/2의 경우에는 1999년 중반까지 1차 기능 규격을 완료할 예정이며, BRAN 전반에 대한 완전한 규격을 2002년까지 완성하는 것을 목표로 하고 있다.

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The Nurse Staffing in Intensive Care Units based on Nursing Care Needs: A Multicenter Study (중환자 간호요구도에 근거한 중환자실 간호사 배치수준 산정 : 다기관 연구)

  • Park, Miok;Yang, Eunjin;Lee, Mimi;Cho, Sung-Hyun;Shim, Miyoung;Lee, Soon Haeng
    • Journal of Korean Critical Care Nursing
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    • v.14 no.2
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    • pp.1-11
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    • 2021
  • Purpose : The aim of this study was to propose appropriate nurse staffing of adult intensive care units considering patients' nursing care needs according to the Workload Management System for Critical Care Nurses (WMSCN). Methods : In a cross-sectional survey conducted in September 2017, 1,786 patients' WMSCN scores, surveys from 2,145 nurses, and administrative data from 118 units in 41 hospitals were analyzed. The means (standard deviations) of the aforementioned scores and nursing hours per patient day were presented. Nurse-to-patient ratios and nurse-to bed ratios for staffing to meet patients' nursing care needs were calculated. Results : The mean WMSCN scores were 109.50±17.17 in tertiary hospitals and 96.38±19.26 in general hospitals. Nursing hours per patient day were 12.47±2.80 in tertiary hospitals and 11.01±2.45 in general hospitals. Nursing hours per patient day correlated with WMSCN scores. Nurse-to-bed ratios required for the provision of ICU nursing care ranged from 1: 0.36 to 1: 0.48. Conclusion : Our findings provide evidence that current ICU nurse staffing is insufficient for meeting patients' nursing care needs. We suggest adjusting the legal standards for adequate nurse staffing considering these needs.