• JSTS:Journal of Semiconductor Technology and Science
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• 제16권3호
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• pp.339-345
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• 2016

This paper presents a two-stage power amplifier MMIC using a $0.4{\mu}m$ GaN-HEMT process. The two-stage structure provides high gain and compact circuit size using an integrated inter-stage matching network. The size and loss of the inter-stage matching network can be reduced by including bond wires as part of the matching network. The two-stage power amplifier MMIC was fabricated with a chip size of $2.0{\times}1.9mm^2$ and was mounted on a $4{\times}4$ QFN carrier for evaluation. Using a downlink LTE signal with a PAPR of 6.5 dB and a channel bandwidth of 10 MHz for the 2.6 GHz band, the power amplifier MMIC exhibited a gain of 30 dB, a drain efficiency of 32%, and an ACLR of -31.4 dBc at an average output power of 36 dBm. Using two power amplifier MMICs for the carrier and peaking amplifiers, a Doherty power amplifier was designed and implemented. At a 6 dB back-off output power level of 39 dBm, a gain of 24.7 dB and a drain efficiency of 43.5% were achieved.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권12호
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• pp.5701-5722
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• 2018

The continuous increase in the cost of energy production and concerns for environmental sustainability are leading research communities, governments and industries to amass efforts to reduce energy consumption and global $CO_2$ footprint. Players in the information and communication industry are keen on reducing the operational expenditures (OpEx) and maintaining the profitability of cellular networks. Meanwhile, network virtualization has been proposed in this regard as the main enabler for 5G mobile cellular networks. In this paper, we propose a generic framework of slice resource provisioning and customized physical resource allocation for energy-efficiency and quality of service optimization. In resource slicing, we consider user demand and population resources provisioning scheme aiming to satisfy quality of service (QoS). In customized physical resource allocation, we formulate this problem with an integer non-linear programming model, which is solved by a heuristic algorithm based on minimum vertex coverage. The proposed algorithm is compared with the existing approaches, without consideration of slice resource constraints via system-level simulations. From the perspective of infrastructure providers, traffic is scheduled over a limited number of active small-cell base stations (sc-BSs) that significantly reduce the system energy consumption and improve the system's spectral efficiency. From the perspective of virtual network operators and mobile users, the proposed approach can guarantee QoS for mobile users and improve user satisfaction.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제11권2호
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• pp.43-50
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• 2022

모바일 데이터의 사용이 늘어나면서 특히 비디오 콘텐츠가 차지하는 비중이 가파르게 증가하고 있다. 모바일 사용자가 지리적으로 원거리에 위치한 클라우드 서버를 통해 데이터를 전달받으면서 발생하는 문제들을 해결하기 위해 사용자와 지리적으로 가까운 엣지 서버에 미리 데이터를 캐싱하는 방법이 많은 주목을 받고 있다. 본 논문에서는 셀룰러 네트워크 환경에서 지연 오프로딩 스킴(delayed offloading scheme)을 적용해 모바일 사용자에게 효과적으로 콘텐츠 파일을 제공하기 위한 SBS 캐싱 기법을 제안하였다. 지연 오프로딩 스킴에서 Macro Base Station(MBS)보다 Small Cell Base Station(SBS)으로부터 데이터를 다운받는 경우 더 적은 비용을 요구하기 때문에 MBS로부터 전송받는 데이터 크기를 최소화하는 것을 목표로 하였다. 모바일 사용자의 이동 경로 확률과 콘텐츠 파일의 인기도를 사용해 SBS에 캐싱할 콘텐츠 파일과 그 크기를 결정하고 SBS의 서비스 범위가 중복되는 것을 고려해 콘텐츠 파일을 재배치하는 캐싱 기법을 제안하였다. 또한 실험을 통해 다른 알고리즘보다 MBS로부터 다운받는 데이터 크기를 줄일 수 있다는 것을 증명하였다.

• ETRI Journal
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• 제37권3호
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• pp.450-459
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• 2015

Small cell networks, as an important evolution path for next-generation cellular networks, have drawn much attention. Different from the traditional base stations (BSs) always-on model, we proposed a BSs on-off model, where a new, simple expression for the probabilities of active BSs in a heterogeneous network is derived. This model is more suitable for application in practical networks. Based on this, we develop an analytical framework for the performance evaluation of small cell networks, adopting stochastic geometry theory. We derive the system coverage probability; average energy efficiency (AEE) and average uplink power consumption (AUPC) for different association strategies; maximum biased received power (MaBRP); and minimum association distance (MiAD). It is analytically shown that MaBRP is beneficial for coverage but will have some loss in energy saving. On the contrary, MiAD is not advocated from the point of coverage but is more energy efficient. The simulation results show that the use of range expansion in MaBRP helps to save energy but that this is not so in MiAD. Furthermore, we can achieve an optimal AEE by establishing an appropriate density of small cells.

• IMMUNE NETWORK
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• 제20권1호
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• pp.10.1-10.14
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• 2020

Immune checkpoint inhibitors (ICIs) have shown remarkable benefit in the treatment of patients with non-small-cell lung cancer (NSCLC) and have emerged as an effective treatment option even in the first-line setting. ICIs can block inhibitory pathways that restrain the immune response against cancer, restoring and sustaining antitumor immunity. Currently, there are 4 PD-1/PD-L1 blocking agents available in clinics, and immunotherapy-based regimen alone or in combination with chemotherapy is now preferred option. Combination trials assessing combination of ICIs with chemotherapy, targeted therapy and other immunotherapy are ongoing. Controversies remain regarding the use of ICIs in targetable oncogene-addicted subpopulations, but their initial treatment recommendations remained unchanged, with specific tyrosine kinase inhibitors as the choice. For the majority of patients without targetable driver oncogenes, deciding between therapeutic options can be difficult due to lack of direct cross-comparison studies. There are continuous efforts to find predictive biomarkers to find those who respond better to ICIs. PD-L1 protein expressions by immunohistochemistry and tumor mutational burden have emerged as most well-validated biomarkers in multiple clinical trials. However, there still is a need to improve patient selection, and to establish the most effective concurrent or sequential combination therapies in different NSCLC clinical settings. In this review, we will introduce currently used ICIs in NSCLC and analyze most recent trials, and finally discuss how, when and for whom ICIs can be used to provide promising avenues for lung cancer treatment.

• 한국농공학회지
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• 제35권3호
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• pp.23-35
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• 1993

The objectives of this paper were to validate the proposed network flow model using field data and to demonstrate the model applicability for various purposes. The model was tested with data from the Banweol watershed, where an intentive streamflow gauging system has been established. Model parameters were not calibrated with field data so that it can be validated as ungaged conditions. Three different schemes were employed to represent the drainage system of the tested watershed : a single, complex, and detailed network. The single network assumed the watershed as a cell, while complex and detailed networks considered several cells. The results from different schemes were individually compared satisfactorily to the observed daily stages at the Banweol reservoir located at the outlet of the watershed. The results from three schemes were in close agreement with each other, Justifying that the model performs very well for different network schemes being used. Daily streamflow from three network schemes was compared for a selected reach within the watershed. The results were very close to each other regardless of network formulation. And the model was applied to simulate daily streamflow before and after the construction of a reservoir at a reach. The differences were discussed, which reflected the influences of the dam construction upon the downstream hydrology. Similar appliocations may be possible to identify the effects of hydraulic structures on streamflow.

• Journal of Power Electronics
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• 제14권5호
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• pp.834-841
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• 2014

This paper proposes new active switched-capacitor and switched-inductor Z-source inverter (ASC/SL-ZSI) topologies, which can provide a higher boost ability with a small shoot-through time. The proposed ASC/SL-ZSIs inherit all of the advantages of the classical ZSI, and have a stronger voltage boost inversion ability when compared with the classical ZSI. Thus, the output ac voltage quality is significantly improved. In addition, more cells can be cascaded in the impedance network in order to obtain a very high boost ability. The proposed topologies can be applied to photovoltaic or fuel-cell generation systems with low-voltage renewal sources due to their wide range of obtainable voltages. Both simulations and the experimental results are carried out in order to verify performance of the proposed topologies.

• 한국기계가공학회지
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• 제19권10호
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• pp.8-15
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• 2020

The diffusion cell method is the main technique employed for the in vitro diffusion test of transdermal drug delivery preparations. Most existing transdermal diffusion devices use a water bath heating structure and direct current motor magnetic stirrer. However, these devices are confronted with problems, such as large volume, incompatible vertical and horizontal diffusion cells, few diffusion cell sets, and poor reliability. To overcome these deficiencies, the system adopts a dry heating method and uses a rotating magnetic field generated by the electromagnetic stirrer to drive the magnetic stirrer. Accordingly, the resulting device is characterized by a simple structure and small volume, convenient operation, compatible vertical and horizontal diffusion cells, and numerous diffusion cell sets. The reliability and practicability of the system is verified by the in vitro percutaneous permeability test of the bisoprolol patch.

• 대한산업공학회지
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• 제29권2호
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• pp.135-144
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• 2003

Traffic performance in a microcellular system is much more affected by cell dwell time and channel holding time in each cell. Cell dwell time of a call is characterized by its mobility pattern, i.e., stochastic changes of moving speed and direction. Cell dwell time provides important information for other analyses on traffic performance such as channel holding time, handover rate, and the average number of handovers per call. In the next generation mobile communication system, the cell size is expected to be much smaller than that of current one to accommodate the increase of user demand and to achieve high bandwidth utilization. As the cell size gets small, traffic performance is much more affected by variable mobility of users, especially by that of pedestrians. In previous work, analytical models are based on simple probability models. They provide sufficient accuracy in a simple second-generation cellular system. However, the role of them is becoming invalid in a picocellular environment where there are rapid change of network traffic conditions and highly random mobility of pedestrians. Unlike in previous work, we propose an improved probability model evolved from so-called Random walk model in order to mathematically formulate variable mobility of pedestrians and analyze the traffic performance. With our model, we can figure out variable characteristics of pedestrian mobility with stochastic correlation. The above-mentioned traffic performance measures are analyzed using our model.

• 한국통신학회논문지
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• 제40권5호
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• pp.812-814
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• 2015

각 기지국이 공통된 자기구성 전략을 사용하고 자신의 상황 고려하여 자신의 셀 접속 방식을 정하는 분산 자기 구성 셀 접속 기법을 제안하고 복잡도가 높은 중앙 집중 집합 접속 방식과의 성능저하 없이 복잡도를 매우 낮출 수 있음을 보였다.