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http://dx.doi.org/10.14775/ksmpe.2020.19.10.008

Multifunctional Transdermal Diffusion Test System  

Gao, Mengyan (Department of Electronic Information Engineering., Yanbian University)
Jin, Hu (Ganting Network Technology Co., Ltd.)
Piao, Xiang Fan (Department of Electronic Information Engineering., Yanbian University)
Publication Information
Journal of the Korean Society of Manufacturing Process Engineers / v.19, no.10, 2020 , pp. 8-15 More about this Journal
Abstract
The diffusion cell method is the main technique employed for the in vitro diffusion test of transdermal drug delivery preparations. Most existing transdermal diffusion devices use a water bath heating structure and direct current motor magnetic stirrer. However, these devices are confronted with problems, such as large volume, incompatible vertical and horizontal diffusion cells, few diffusion cell sets, and poor reliability. To overcome these deficiencies, the system adopts a dry heating method and uses a rotating magnetic field generated by the electromagnetic stirrer to drive the magnetic stirrer. Accordingly, the resulting device is characterized by a simple structure and small volume, convenient operation, compatible vertical and horizontal diffusion cells, and numerous diffusion cell sets. The reliability and practicability of the system is verified by the in vitro percutaneous permeability test of the bisoprolol patch.
Keywords
Transdermal Diffuser; Electromagnetic Stirring; MCU;
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