• Environmental and Resource Economics Review
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• v.14 no.2
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• pp.337-379
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• 2005

This choice experiments study values the non-market benefits of water quality improvements in Paldang Reservoir and Han River, located in Korea. A fractional factorial orthogonal design was used to produce four different choice sets per respondent, before employing choice examples to screen out irrational responses. The panel mixed logit model (with normal distributions for the attributes) fit the data best, indicating that allowing for both heterogeneous preferences across households and correlation between repeated choices may represent actual choice behaviors best of all the estimated models. The significant standard deviations of the random attributes suggest that the taste for each attribute may vary considerably in the population. The annual benefits to the Seoul Metropolitan area for a small (large) enhancement of the clarity of water, a gradual removal of unpleasant waters, and a gradual improvement in biodiversity, were estimated to be some 1.5 trillion (1.7 trillion) Won, 2 trillion Won, and 1.7 trillion Won, respectively, with 1.8~2.6 trillion Won for at least two of them occurring together. The study also discusses potential biases germane to choice experiments studies of this type.

• Molecules and Cells
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• v.39 no.2
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• pp.103-110
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• 2016

As a degenerative joint disease, osteoarthritis (OA) constitutes a major cause of disability that seriously affects the quality of life of a large population of people worldwide. However, effective treatment that can successfully reverse OA progression is lacking until now. The present study aimed to determine whether two small non-coding RNAs miR-29a and miR-140, which are significantly down-regulated in OA, can be applied together as potential therapeutic targets for OA treatment. MiRNA synergy score was used to screen the miRNA pairs that potentially synergistically regulate OA. An in vitro model of OA was established by treating murine chondrocytes with IL-$1{\beta}$. Transfection of miR-29a and miR-140 via plasmids was investigated on chondrocyte proliferation and expression of nine genes such as ADAMTS4, ADAMTS5, ACAN, COL2A1, COL10A1, MMP1, MMP3, MMP13 and TIMP metallopeptidase inhibitor 1 (TIMP1). Western blotting was used to determine the protein expression level of MMP13 and TIMP1, and ELISA was used to detect the content of type II collagen. Combined use of miR-29a and miR-140 successfully reversed the destructive effect of IL-$1{\beta}$ on chondrocyte proliferation, and notably affected the MMP13 and TIMP1 gene expression that regulates extracellular matrix. Although co-transfection of miR-29a and miR-140 did not show a synergistic effect on MMP13 protein expression and type II collagen release, but both of them can significantly suppress the protein abundance of MMP13 and restore the type II collagen release in IL-$1{\beta}$ treated chondrocytes. Compared with single miRNA transfection, cotransfection of both miRNAs exceedingly abrogated the suppressed the protein production of TIMP1 caused by IL-$1{\beta}$, thereby suggesting potent synergistic action. These results provided1novel insights into the important function of miRNAs' collaboration in OA pathological development. The reduced MMP13, and enhanced TIMP1 protein production and type II collagen release also implies that miR-29a and miR-140 combination treatment may be a possible treatment for OA.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.11
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• pp.3260-3268
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• 2009

A test apparatus has been fabricated to simulate chemical effect on head loss through a strainer in a pressurized water reactor (PWR) containment water pool after a loss of coolant accident (LOCA). Tests were conducted under condition of same ratio of strainer surface area to water volume between the test appratus and the containment sump. A series of tests have been performed to investigate the effects of spray, existence of calcium-silicate with tri-sodium phosphate (TSP), and composition of materials. The results showed that head loss across the chemical bed with even a small amount of calcium-silicate insulation instantaneously increased as soon as TSP was added to the test solution. Also, the head loss across the test screen is strongly affected by spray duration and is increased rapidly at the early stage, because of high dissolution and precipitation of aluminum and zinc. After passivation of aluminum and zinc by corrosion, the head loss increase is much slowed down and is mainly induced by materials such as calcium, silicon, and magnesium leached from NUKONTM and concrete. Furthermore, it is newly found that the spay buffer agent, tri-sodium phosphate, to form protective coating on the aluminum surface and reduce aluminum leaching is not effective for a large amount of aluminum and a long spray.

• Journal of KIISE:Information Networking
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• v.32 no.3
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• pp.415-426
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• 2005

Wireless internet, which becomes a hot social issue, has limitations due to the following characteristics, as different from wired internet. It has low bandwidth, frequent disconnection, low computing power, and small screen in user terminal. Also, it has technical issues to Improve in terms of user mobility, network protocol, security, and etc. Wireless internet server should be scalable to handle a large scale traffic due to rapidly growing users. In this paper, wireless internet proxy server clusters are used for the wireless Internet because their caching, distillation, and clustering functions are helpful to overcome the above limitations and needs. TranSend was proposed as a clustering based wireless internet proxy server but it has disadvantages; 1) its scalability is difficult to achieve because there is no systematic way to do it and 2) its structure is complex because of the inefficient communication structure among modules. In our former research, we proposed the All-in-one structure which can be scalable in a systematic way but it also has disadvantages; 1) data sharing among cache servers is not allowed and 2) its communication structure among modules is complex. In this paper, we proposed its improved scheme which has an efficient communication structure among modules and allows data to be shared among cache servers. We performed experiments using 16 PCs and experimental results show 54.86$\%$ and 4.70$\%$ performance improvement of the proposed system compared to TranSend and All-in-one system respectively Due to data sharing amount cache servers, the proposed scheme has an advantage of keeping a fixed size of the total cache memory regardless of cache server numbers. On the contrary, in All-in-one, the total cache memory size increases proportional to the number of cache servers since each cache server should keep all cache data, respectively.

• Korean Journal of Food Science and Technology
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• v.27 no.6
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• pp.891-896
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• 1995

In order to screen natural inhibitor of tyrosinase which catalyzes an enzymatic browning of some foods and in vivo synthesis of melanin, inhibitory effect of 129 edible plants and 15 chemical compounds on the in vivo melanin synthesis by mushroom tyrosinase was analyzed. Among leafy vegetables tested, radish bud, red chicory, Shepherd's purse and small green onion were found to have more than 50% tyrosinase inhibition effect in the descending order. Chinese radish and garlic in root vegetables, and nameko, shiitake and oyster mushroom in mushrooms, and teas showed also more than 50% inhibition effect. Among fruit vegetables tested, red pepper, Chinese quince and avocado were found to have more than 50% tyrosinase inhibition effect, while fruits generally showed low inhibitory effect. Medicinal plants which inhibit tyrosinase more than 50% were mume fructus>cinamomi ramulus>rubi fructus>mori cortex>biotae orientalis folium>puerariae radix, and herbs with more than 50% inhibitory effect were allspice>clove>mustard. In some chemical compounds tested, 4-hexylresorcinol, L-cysteine, glutathione, sodium bisulfite and kojic acid showed powerful inhibition effect on mushroom tyrosinase.

• Journal of the Korea Society of Computer and Information
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• v.11 no.2 s.40
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• pp.187-199
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• 2006

This paper proposes the design of user centric pavilion information guide system based on mobile device such as PDA. which is composed of system interface factors as user wants. The suggested information guide system is convenient for user carrying because it is based on PDA mobile device and the used liquid browser system makes all data information displayed on a small screen in contrast with the other browser system. Indeed, factors of system interface can be re-composed by user interaction. And this system can effectively provide the detail information about the exhibited objects as various media data such as text, image, voice, music, video etc. The proposed system is made up of media database server. mobile system control server and mobile system interface which accepts user interaction and displays the information. Each system is networked based on TCP/IP and uses XML (extensible Markup Language) and JAVA 2 micro edition to be able to update data. This feature enhances a wide use to be able to load this system on the any mobile device.

• The Journal of the Korea Contents Association
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• v.14 no.9
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• pp.14-23
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• 2014

Existing attending management systems require a high cost and are lack of convenience. In this paper, we propose a convenient and practical attending management system as follows: First, our system allows us to construct an attendance book in an easy and simple way. A professor does not have to provide the information of students using the small screen of his smartphone. Instead, each student manages his own information via the app designed for a student in our system. Then the professor can construct the attendance book using another app designed for the professor by confirming the requests from the app designed for a student. Second, our system enables a professor to utilize the pictures of students as well as other information of students to have a good relationship with students. Third, our system provides a functionality of checking attendance automatically by calling the names of students via the app designed for the professor. Then the professor has only to match the name with the face of each student. Fourth, our system provides a functionality of checking attendance in a very fast manner. Our system can complete this behavior within a short time since all students can join the attendance simultaneously by using the app designed for the student. Fifth, our system can prevent an illegal attendance easily by utilizing the distance information.

• Korean Journal of Plant Tissue Culture
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• v.26 no.2
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• pp.121-126
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• 1999

Calli were induced from the petiole explants of Pimpinella brachycarpa on MS medium supplemented with 0.5 mg/L 2,4-D and 0.1 mg/L BA after four weeks of culture. Compact clusters of small and dense cells among these calli were selected and suspension-cultured as the source of embryogenic calli. When transferred to MS medium with 0.1 mg/L NAA, the suspension-cultured cells grew to embryogenic callus. Somatic embryos derived from these embryogenic calli developed into plantlets. The cDNA library was constructed in the embryogenic callus and in order to screen the cDNA library, these cDNAs were plated at a density 1.5 $\times$ 10^5 plaques per 15 cm petridish. Among 19 clones showing preferential hybridization with petiole HD-Zip gene, five clones were obtained after second screening. Four clones among them, were highly homologous to P. brachycarpa shoot-tip Phz4 gene, but one clone, Phc5 was about 1.5 kb which has an extra 163 bp to 5' upstream of Phz4. The Phc5 was 1,531 bp containing poly A tails of 18 bases. ATG start codon for Phc5, was located at position 284 with an open reading frame of 906 by which encodes a polypeptide of 302 amino acids. The Phc5 protein revealed that the polypeptides between 135 and 195 contain a homeodomain as the `leucine zipper' motif.

• Journal of Radiation Protection and Research
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• v.40 no.4
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• pp.211-215
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• 2015

In case of radiation emergencies, radioactive materials released into environments can cause internal exposure of members of the public. Even though whole body counters are widely used for direct measurement of internally deposited radionuclides, those are not likely to be used at the field to rapidly screen internal exposure. In this study, we estimated the counting efficiencies of portable NaI detector for different size BOMAB phantoms using Monte Carlo transport code to apply handheld gamma spectrometers for rapid screening of internal exposure following radiological accidents. As a result of comparison for two counting geometries, counting efficiencies for sitting model were about 1.1 times higher than those for standing model. We found, however, that differences of counting efficiencies according to different size are higher than those according to counting geometry. Therefore, we concluded that when we assess internal exposure of small size people compared to the reference male, the body size should be considered to estimate more accurate radioactivity in the human body because counting efficiencies of 4-year old BOMAB phantom were about 2.4~3.1 times higher than those of reference male BOMAB phantom.

• Journal of the Korea Society of Computer and Information
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• v.13 no.7
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• pp.91-98
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• 2008

In digital broadcasting, it is possible to multiplex maximum one hundred audio or music programs into MPEG-2 transport stream, which is suitable for transmitting through one channel. In order to check if multiplex music programs are transmitted well, we need a multiplex audio monitoring system that monitors the programs in real-time. In analog broadcasting, we have used hardware-based audio monitoring system for a small number music programs. However, the effectiveness of hardware-based audio monitoring system from the cost and function viewpoint is so low that a new system is needed for digital broadcasting. In this paper, we have designed and implemented a software-based audio monitoring system to satisfy these requirements. In this implementation, only one PC is used without other hardware facilities, and the system monitors digital broadcasting music programs effectively. Transmitted digital broadcasting streams are demultiplexed into many music programs and the realtime value of audio level and packet error information for these programs are displayed in the screen. Thus, the system detects and shows the abnormal transmitting programs automatically. Simulation results show that effective realtime multiplex audio monitoring is possible for digital broadcasting music programs.