• The Journal of Internal Korean Medicine
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• v.28 no.2
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• pp.217-229
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• 2007

Objectives : The aim of this experimental study was to investigate the effects of Bojangjisa-tang on anticatharsis by using mice and Guinea pigs. Methods : We observed the actions on gastrointestinal smooth muscles, on the transportability of small and large intestines and on diarrhea induced by castor oil, philocarpine, and barium chloride. Results : Bojangjisa-tang showed alleviation of the contraction of gastrointestinal smooth muscles induced by acetylcholine chloride and barium chloride. The transportability of the large intestine was constrained by Bojangjisa-tang, which also showed substantial anti-cathartic effects on diarrhea induced by castor oil, philocarpine and barium chloride. Conclusion : These results demostrate that Bojangjisa-tang has advantageous effects on drug-induced diarrhea and will contribute to the development of diarrhea treatment through further related studies.

• The Korean Journal of Food And Nutrition
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• v.6 no.3
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• pp.219-230
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• 1993

This research aims to study the changes In gastrointestinal function attributed to aging In human. The thresholds for recognition and detection of flavors became elevated and salivary gland acinar cells decreased in the old age. But most esophageal function remained relatively Intact. Although gastric emptying time has been slowed with aging, the total intestinal transit time did not differ. Atropic gastritis due to H. pylori in old man decreased secretion of acid and Intrinsic factor and absorbability of calcium and iron. Pancreatic secretion is droned in older persons. Prevalence of gallstones rised with age. Liver size and portal blood flow decreased significantly with age. Mucosal surface area has been reported to be slightly diminished in the aging man. Glucose transporters decreased and Insulin tolerance Increased. Absorption of aromatic amino acid is diminished with age. Dietary protein In that aging human increased fecal nitrogen excretion. Vitamin A tolerance increased. Vitamin D receptor concentration decreased and resistance to 1,25-(OH)2D3 action increased. Permeability of aging small Intestine Increased. Zinc balance dirt not differ Copper absorption appeared not to be significantly affected by age. Neurotensin secretion decreased thus slowed colonic peristaltic movements and Intestinal mucosal growth.

• Journal of Korea Foundry Society
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• v.6 no.1
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• pp.5-11
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• 1986

The Wear Characteristics of Al-Si alloys were investigated with various Si contents by using the not-dispersed alloys and uncoated-graphite dispersed alloys. Uncoated-graphite dispersions were accomplished by Vortex method carrying 1 hr. heating at $400^{\circ}C$ on uncoated-graphite. Wear loss were increased by increasing Si contents at the elevated final load. Hyper-eutectic alloys showed higher wear resistance values at the small final load of 2.1Kg and 3.2Kg, but at the more increased final load, hypo-eutectic alloys showed higher wear resistance values than hyper-eutectic alloys. The property of wear resistance of uncoated-graphite dispersed Al-Si alloys showed more good values than not-dispersed alloys. This peroperty of increased war resistance were resulted from lubricating action of dispersed graphite.

• Genomics & Informatics
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• v.9 no.4
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• pp.173-180
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• 2011

Recent trends in generating multiple, large-scale datasets provide new challenges to manipulating the relationship of different types of components, such as gene expression and drug response data. Integrative analysis of compound response and gene expression datasets generates an opportunity to capture the possible mechanism of compounds by using signature genes on diverse types of cancer cell lines. Here, we integrated datasets of compound response and gene expression profiles on NCI60 cell lines and constructed a network, revealing the relationship for 801 compounds and 341 gene probes. As examples, obtusol, which shows an exclusive sensitivity on a small number of colon cell lines, is related to a set of gene probes that have unique overexpression in colon cell lines. We also found that the SLC7A11 gene, a direct target of miR-26b, might be a key element in understanding the action of many diverse classes of anticancer compounds. We demonstrated that this network might be useful for studying the mechanisms of varied compound response on diverse cancer cell lines.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.529-530
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• 2006

An efficient sensing scheme adoptable in DC-DC converter is described. The output voltage of the whole DC-DC converter is fed back to the input voltage of the sensor. The comparison in the sensor is accomplished by a current push-pull action. With a fixed reference, the comparator can be embodied based on (W/L) ratios. The current-mode scheme benefits the system better than a conventional voltage-mode one in terms of small area, low power consumption.

• Structural Engineering and Mechanics
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• v.42 no.1
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• pp.55-72
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• 2012

Precast-cast insitu concrete bridge construction is widely practiced for small to medium span structures. These bridges consist of precast pre-stressed concrete beams of various cross-sections with a cast in-situ reinforced concrete slab. The connection between the beams and the slab is via shear links often included during the manufacturing process of the beams. This form of construction is attractive as it provides for standardisation, reduced formwork and construction time. The assessment of the integrity of shear connectors in existing bridges is a major challenge. A procedure for assessment of shear connectors based on vibration testing and finite element model updating is proposed. The technique is applied successfully to a scaled model bridge model and an existing bridge structure.

• Coupled systems mechanics
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• v.1 no.1
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• pp.99-113
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• 2012

We present a monolithic semi-implicit algorithm for solving fluid-structure interaction problem at small structural displacements. The algorithm uses one global mesh for the fluid-structure domain obtained by gluing the fluid and structure meshes which are matching on the interface. The continuity of velocity at the interface is automatically satisfied and the continuity of stress does not appear explicitly in the global weak form due to the action and reaction principle. At each time step, we have to solve a monolithic system of unknowns velocity and pressure defined on the global fluid-structure domain. Numerical results are presented.

• Structural Engineering and Mechanics
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• v.28 no.3
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• pp.317-334
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• 2008

Seismic performance of coupling beams not designed for ductility is examined. Eight 1:4 scale coupling beam specimens, with seven reinforced concrete sections and one composite section, were tested under cycles of push-pull action. Characteristics of the specimens include moderate shear span ratio in the range of 2.5-3.5, high main reinforcement ratio at 3-4% and small to large stirrup spacing with 90- degree hooks. All the reinforced concrete specimens failed in a brittle manner. Displacement ductility of specimens with large stirrup spacing (${\geq}$140 mm) is in the range of 3 to 5. Seismic performance of the specimens is also examined using the ultimate drift angle and the amount of energy dissipated. Correlating the test data, an empirical relationship is proposed to estimate the ultimate drift angle of a class of coupling beams considered in the study not designed for ductility.

• 제어로봇시스템학회:학술대회논문집
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• 1998.10a
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• pp.141-146
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• 1998

This paper presents a scheme to actively control the vertical vibration of aerial vehicles due to the disturbances such as the sudden change of derricking angle and the external forces by using a small plunger attached to the derricking cylinder. Simulations show that the 1st mode vibration is suppressed efficiently by the proposed method without exciting the higher modes' vibration. Detailed mathematical model of the aerial vehicle, its vibration characteristics, detection method of the 1st mode vibration and the controller design based on the lag-element and the disturbance observer are described.

• Journal of the Korean Chemical Society
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• v.11 no.1
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• pp.33-37
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• 1967

The influence of impurities contained in Marmatite ores on leaching of zinc was investigated. The zinc sulfide having the same crystal structure of natural Sphalerite was prepared by heating the zinc sulfide chemically precipitated, at $650^{\circ}C$ in nitrogen atmosphere. The activation energy of the sample was 25.8 kcal per mole in the leach test when oxygen partial pressure was 5 atm. and the value was exceedingly high compared to that obtained in Marmatite ores. Synthetic zinc sulfides added with small amount of each impurities were treated in same procedure. As a result, it was found that the leaching velocity was accelerated sharply when about 1 percent of $Cu^{++}$ was blended to the sample. Larger amount of iron has also same effect but the effect was minor compared to the copper. The other impurities indicated no appreciable catalytic action.