• 생약학회지
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• 제10권1호
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• pp.17-22
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• 1979

The investigation is involved with the effect of Capsicum component on the drug metabolism. To investigate the effects of Capsicum component on, in vivo, drug metabolism in rat, Capsicum acetone extract was given intraperitoneally to mice or rats. The duration of loss of righting reflex was determined as hexobarbital sleeping time in mice. Plasma hexobarbital concentration was also measured by Brodie's method. The rats were pretreated with Capsicum extract acutely or chronically. As the results, hexobarbital sleeping time and plasma hexobarbital concentration were increased by 31.2% and 12.3% in acute study, whereas were decreased by 27.5% and 23.0% in chronic study. An attempt was made to determine if there were any influences on enzyme activities in rats pretreated with Capsicum extract chronically. Microsomal fraction was isolated from rat liver and quantity of cytochrome $P_{450}$ and $b_5$ in the microsomal fraction were determined by Omura's method. It was found that the quantity of cytochome $P_{450}$ was increased by 22.4%. The results suggest that microsomal drug metabolizing enzyme may be induced by chronic administration of Capsicum component, whereas it may be inhibited by acute administration of Capsicum component.

• 부모자녀건강학회지
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• 제17권1호
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• pp.1-7
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• 2014

Purpose: The research was to identify menstrual regularity & mental health-related factors on unmarried women of childbearing age and provide a raw material in terms of setting up health policy. Methods: The KNHANE V-3 (The Fifth Korea National Health and Nutrition Examination Survey) was used and implemented through spss 18.0. Results: In general characteristics, there wasn't any remarkable difference between 20s and 30s. Looking further Mental health-related factors, stress was higher in 30s (p=.010). In 30s of irregularity mensutration women, it was accounted for 12.5% over than 3months experienced. General characteristics varied by menstrual regularity were age (p=.044), education level (p=.035) and in terms of mental health-related factors, they were stress (p=.044), sleeping time (p=.039). Multiple regression analysis was carried out to identify how influential these factors are on menstrual regularity. As a result, age, education level, sleeping time & stress was the most influence factors. Conclusion: The research had some limitations to specify and approach the feature of target in depth through KNHANE V-3. Thus, if the basic analysis regarding the menstrual problem in relation to local society was conducted on the basis of the result of research, it could help developing the promotion of health program and make the application easier.

• Advances in Traditional Medicine
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• 제6권3호
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• pp.221-231
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• 2006

The aim of the present study is to investigate central nervous system (CNS) activity of the methanol extracts of leaves of Caesalpinia bonducella (MECB) and stem bark of Bauhinia racemosa (MEBR) (Caesalpinaceae) in Swiss albino mice and Wistar albino rats. General behavior, exploratory behavior, muscle relaxant activity and phenobarbitone sodium-induced sleeping time were studied. The results revealed that the methanol extracts of leaves of Caesalpinia bonducella at 100 - 200 mg/kg and stem bark of Bauhinia racemosa 100 - 200 mg/kg caused a significant reduction in the spontaneous activity (general behavioral profile), remarkable decrease in exploratory behavioral pattern (Y-maze and head dip test), a reduction in muscle relaxant activity (rotarod and traction tests), and also significantly potentiated phenobarbitone sodium-induced sleeping time. The results suggest that MECB and MEBR exhibit CNS depressant activity in tested animal models.

• Toxicological Research
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• 제13권3호
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• pp.193-196
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• 1997

Matricaria Chammomillal L., Foemiculum Vulgare mill, and Plantago Psylium L. have been screened for their hepato protective activities against liver damge induced by $CCl_4$ intoxication in mice. Hydroalcoholic extractions (2:8) of herbal drugs were concentrated in vacuo and concentrated crude extracts of Matrica Chammomilla L. and Foeniculum Vulgare mill were orally administered at doses of 100 mg/kg, 200 mg/kg, 400 mg/kg, and 800 mg/kg. Plantago Psyllium was given at doses of 50 mg/kg, 100 mg/kg, 200 mg/kg, and 400 mg/kg. Liver protective activities of these herbs were determined after administration of $CCl_4$ Liver size, serum enzyme activities, sleeping time, and histopatology of the liver were examined one hour after administration of $CCl_4$. ALT and AST activities, liver weight and sleeping time decreased in groups that received 400 mg/kg of Matricaria Chammomilla L. or Foeniculum Vulgare. Histological investigation showed significant increase in hepatic cell regeneration and reduction in liver injury. The group that received 100 mg/kg Plantago Psylium showed liver protection but protection was not significant in other doses.

• 한국보건간호학회지
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• 제31권3호
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• pp.451-463
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• 2017

Purpose: The purpose of this study is to investigate the drinking, stress, and sleep on depression of Korean obese women. Methods: The data of this study were derived from the Sixth Korea National Health and Nutrition Examination Survey (KNHANES VI-3), conducted from January to December 2015 by Korea Centers for Disease Control and Prevention. The study subjects were 935 adult women between 20 and 70 years old (Body Mass Index${\geq}25$). The data were analyzed by the complex sampling design method applying the weights to the IBM SPSS 23.0 program. Results: The study result showed that the frequency of binge drinking, stress perception, sleeping time and depression of Korean obese women showed significant differences according to age group. In the 20-30's, the stress and sleeping time, the 40-50's were drinking at once, the frequency of drinking and stress, and the drinking and stress at 60-70's were significantly associated with an increased risk of depression in obese women. Conclusion: The intervention program for the management of depression in Korean obese women should include the strategies for managing stress and drinking, taking into account differences according to age.

• 대한한방소아과학회지
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• 제24권3호
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• pp.138-149
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• 2010

Objectives: The purpose of this study is to estimate genetic and environmental factors which can effect growth, and predict final height using this factors. Methods: Correlation analysis and regression analysis were conducted between measurements of height and Genetic & environmental factors through survey from 1352 child & adolescent patients. Results: Factors which have correlation with height percentile are MPH(Mid-Parental Height), NBW(Neonatal body weight), anorexia, dyspepsia, atopic dermatitis, frequency of breakfast and quality of sleeping time. MPH has moderate relation, NBW and anorexia have fair relation, and other factors have linear but poor relation. Regression equation from factors which have correlation and height percentile has 26.9% of predictive power. Regression equation considering only genetic factor has 20.4%. MPH has the most effect on height percentile. Anorexia has more effect than NBW. Other factors also have small and similar effect. Conclusions: Height of parents has the most effect on growth, anorexia, dyspepsia, atopic dermatitis, frequency of breakfast and quality of sleeping time also has effect.

• 동의생리병리학회지
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• 제28권6호
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• pp.643-649
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• 2014

This study was designed to report treatment for Behcet's disease with arthritis We treated 2 Behcet's disease patients with arthritis. A 46-year-old female patient was treated with Cheongsimyeonja-tang. Another case, 44-year-old female patient was diagnosed as Sjogren's disease at first and diagnosed as The Behcet's diseases about 1 year later, treated with Cheonglijagam-tang. The progress was evaluated with the visual analogue scale for joint pain and hot flush, and length of sleeping time. There was improvement in the symptoms of visual analogue scale for joint pain and hot flush, also length of sleeping time. Cheongsimyeonja-tang, Cheonglijagam-tang can be considered as a treatment for patient diagnosed as Behcet's disease suffering from arthritis, especially.

• 한국직업건강간호학회지
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• 제15권1호
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• pp.58-71
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• 2006

Purpose: This study was performed to identify workers' Job stress status and to analyse the influencing factors. Method: Data were collected from 456 workers with Korean Occupational Stress Questionnaire Short Form(KOSQ SF) and analysed using descriptive statistics, t-test, ANOVA. Results: Total job stress status of men was slightly lower than Korean workers' standard. In case of women, the score of total job stress was lower than Korean workers' standard. The most significant influencing factors to stressors were insufficient sleeping time and self cognitive bad health condition. Among seven domains of job stressors, job demand was affected by 8 characteristics. Conclusion: This study indicated that workers' job stress level were various by their characteristics except workplace size. The development of stress management programs by types of industry is required. On the base of the model program, planning of customized program for every company or employee is required. High job demand, insufficient job control, insufficient sleeping time, bad health condition are the key factors of workers' job stress in this study. The change of workers' health behavior with supportive environment is essential to stress management program. More researches for adding physical environment domain to KOSQ SF are expected.

• 한방안이비인후피부과학회지
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• 제30권3호
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• pp.231-238
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• 2017

Objectives : The purpose of this study is to report the efficacy of using oriental medical treatment(herbal medicine, acupuncture) with melonis Calyx Vomiting Therapy(MCVT) for trigeminal neuralgia. Methods : We experienced one cases of trigeminal neuralgia treated with oriental medical treatment and melonis Calyx Vomiting Therapy. MCVT is a traditional treatment, which induces vomiting by eating melonis Calyx powder with water. To evaluate the results of this treatment, we used the Visual Analogue Scale(VAS) and sleeping time. Results : After using MCVT with oriental medical treatment, VAS, sleeping time and clinical symptoms of the patient were improved remarkably. Conclusions : This study suggests that using MCVT with oriental medical treatment is effective on trigeminal neuralgia.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1978년도 학술대회지
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• pp.85-92
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• 1978

The aim of the double blind test was to assess the prophylactic and therapeutic efficacy of the preparation GINSANA, containing the standardized ginseng extract PHARMATON G115,. The determination was carried out with special emphasis on the following features : general physical condition, physical performance, mental performance, enjoyment of life/mood, concentration and memory, as well as sleeping habits. Sixty test persons took part in the study, men and women between the ages of 22 and 80. The 90-day test was carried out in the form of a double blind experiment. Experimental measurements were made and the persons were also questioned. The reaction time, the optical merging threshold, the coordination of both hands and the recovery quotients, as well as the recovery rates were analyzed. The results for the serum group were clearly better than those for the placebo group, particularly for the characteristics: general physical condition, physical performance and sleeping habits. The results of the test methods used, especially with regard to the reaction time, the coordination of both hands, the recovery quotient and the recovery period, permit the following conclusion to be drawn: when administered for several weeks, GINSANA has a positive action, in the sense of an activation of the entire personality by the ginseng glycosides contained in the standardized Extracts G115.