• 약학회지
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• 제38권5호
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• pp.586-594
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• 1994

The general pharmacological effects of DWQ-013, a new synthetic quinolone antibacterial agent, were examined on the central nervous system in experimentral animals and the following results were obtained. Drug interaction of DWQ-013 with theophylline, fenbufen and nonsteroidal antiinflammatory drugs was also examined. DWQ-013 decreased touch escape effect on the general behavior and decreased body temperature at a concentration of 1000 mg/kg in mice. But DWQ 013 had no effect on the locomotor activity, rotarod perfomance and traction test in mice. Furthermore, DWQ-013 increased pentobarbital-induced sleeping time and affected the onset time in acetic acid-induced writhing test in mice. DWQ-013 reduced onset time and death time on strychnine-induced convulsions and death time on pentylenetetrazole-induced convulsions at a concentration of 1000 mg/kg in mice. But, the drug had no effect on the electroshock. DWQ-013 did not interact with fenbufen and any other NSAIDs but it did interact with theophylline. From these results, it could be suggested that DWQ-013 had less pharmacological effect than other quinolones on the central nervous system.

• 대한간호학회지
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• 제54권2호
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• pp.139-150
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• 2024

Purpose: This study aimed to identify changes in sleep patterns and fatigue levels during consecutive night shifts among shift nurses and to determine the association between sleep parameters and increased fatigue levels during work. Methods: This prospective observational study employing ecological momentary assessments was conducted using data collected from 98 shift nurses working in Korean hospitals between June 2019 and February 2021. The sleep patterns were recorded using actigraphy. The participants reported their fatigue levels at the beginning and end of each night shift in real time via a mobile link. Linear mixed models were used for the analysis. Results: Nurses spent significantly less time in bed and had shorter sleep durations during consecutive night shifts than on off-duty days, whereas their wake times after sleep onset were much longer on off-duty days than on on-duty days. Fatigue levels were higher on the second and third night-shift days than on the first night-shift days. A shorter time spent in bed and asleep was associated with a greater increase in fatigue levels at the end of the shift than at the beginning. Conclusion: Nurses experience significant sleep deprivation during consecutive night shifts compared with off-duty days, and this sleep shortage is associated with a considerable increase in fatigue levels at the end of shifts. Nurse managers and administrators must ensure sufficient intershift recovery time during consecutive night shifts to increase the time spent in bed and sleeping.

• Journal of Hospice and Palliative Care
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• 제8권1호
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• pp.37-44
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• 2005

목적: 조혈모세포이식환자의 입원 후 수면양상의 변화 및 수면장애를 파악함으로써, 조혈모세포이식 환자의 수면을 위한 간호중재를 개발하기 위한 기초자료를 제공하기 위하여 시도하였다. 방법: 서울 C대학병원에 2002년 8월부터 2003년 8월까지 조혈모세포이식를 위해 입원한 환자 52명을 대상으로, PSQI와 수면양상 설문지를 이용하여 조사하였다. 조사된 자료는 SAS프로그램을 이용하여, 입원전과 입원 후의 PSQI 차이는 paired t-test로, 입원시와 퇴원시의 수면양상의 변화는 카이검정과 Fisher's exact test로 분석하였다. 결과: 대상자의 입원 후 한 달 동안 PSQI점수는 11.8점으로 입원 전 한달 동안의 5.3점보다 유의하게 높았다(t=11.41, P=0.0000). 7개의 항목 즉 수면의 질, 수면지연, 수면기간, 수면의 효율성, 수면장애, 수면제 복용, 일상생활의 장애 모두에서 입원 후 한달 동안의 PSQI점수는 입원 전 한달 동안에 비하여 유의하게 높았다. 대상자의 입원시와 퇴원시의 수면양상을 살펴보면 취침시각, 잠드는데 걸리는 시간, 기상시각, 총 수면시간, 낮잠 시간, 밤에 자다 깨는 횟수, 수면제 사용 횟수, 잠이 안 오면 하는 일, 수면을 취할 수 없는 이유 등에서 유의한 차이가 있었다. 결론: 조혈모세포이식환자는 입원 후 PSQI에 의한 수면의 질 점수가 입원 전에 비해 유의하게 높아, 입원기간동안 수면에 어려움이 많은 것을 알 수 있었다. 수면양상도 입원시에 비해 퇴원시 취침 시간, 잠드는데 걸리는 시간, 기상시각, 총 수면시간, 낮잠시간, 밤에 자다 깨는 횟수, 수면제사용횟수, 잠이 안 오면 하는 일, 수면을 취할 수 없는 이유의 항목에서 유의한 변화가 있음을 알 수 있었다.%), 산재형 47명(17.0%), 가정형 34명(12.3%)의 순으로 나타났다. 결론: 본 연구의 결과 입원환자 가족의 호스피스에 대한 인지 및 요구도는 전반적으로 높았으며 일반적 특성에 따라 호스피스 인지 및 요구도에 차이를 보였다. 따라서 대상자의 일반적 특성을 고려한 개별적이고 다양한 접근을 시도할 수 있는 호스피스 교육 및 중재 프로그램을 개발하여 수행해야 할 것이다.'(10면)이나, 비참석가족들은 '외로움(7명)', '경제적 문제/역할수행상의 어려움'(7명)의 빈도였다. 대처방법에서는, '영적 승화'(13명), '일상생활에의 몰두'(10명), '애도과정에의 몰입(계속 슬퍼함)'(3명)으로 응답하였다. 병원으로부터 사별가족모임의 초대장을 받았을 때의 느낌에 대해서는 '반가움과 고마움'(21명), '슬픔'(4명), '괴로움'(4명), 무응답(11명)이었다. 비 참석 가족들은 '반가움과 고마움'(4명)이었다. 사별가족 모임 참석에 대한 망설임의 유무와 이유에 대해서는, '망설이지 않았다'(34명)가 '망설였다'(6명)보다 높게 나타났다. 사별가족모임에 참석한 후의 소감, 개선사항, 아쉬운 점에 대한 질문에는, 대부분의 응답자들이 '의미 있는 시간이었다', '사별가족에 대한 배려와 관심에 대해 감사한다.'라는 긍정적인 응답이 있었고, '고인에 대한 회상을 할 수 있는 자리여서 좋았다.' '사별가족모임이 일년에 한 번이 아니라 계속적으로 있었으면 한다.', '한편은 슬프고 한편은 기쁘다.' 등의 의견이 있었다. 사별 후 느끼는 가장 큰 어려움에 대해 참석가족은, '우울감'(10명), '외로움'(7명)의 빈도가 높았고, '그리움'(1명), '경제적/역할상 어려움'(4명), 무응답(6명)으로, '우울감'이 가장 큰 어려움으로 나타났다

• 대한의료기공학회지
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• 제15권1호
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• pp.61-70
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• 2015

Objectives : The purpose of this study is to investigate the effects of Su-Gi therapy for Insomnia by using ISI scores and PSQI test. Methods : We investigated 4 patients on condition of Insomnia who was hospitalized in the M Korean medicine hospital in Gyeonggi Province from 8th June, 2015 to 21st October, 2015. The Su-Gi therapy was treated on patients once a day for 10 minutes. We figured out the outcome by using ISI scores and PSQI test. Results : There were no differences on average sleeping time and the time to falling a sleep. Meaningful outcomes in values of ISI scores and PSQI test was not deduced after Su-Gi therapy. There were some progress on disturbance of daytime due to insomnia, ISI scores and PSQI test. In the Correlation analysis of outcomes of before and after the Su-Gi therapy, there were some improvements on ISI scores and PSQI tests and some questionnaire but were not enough to reach meaningful outcomes. We concluded that the more treatment time is needed to improve the condition of patients on insomnia as we see in PSQI test, one month is minimum period time to draw the conclusion. Conclusions : Theses outcomes suggest a possibilities that improvements who are suffering from insomnia can be get well when the Su-Gi therapy is performed for sufficient moments.

• 한국식생활문화학회지
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• 제27권1호
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• pp.38-48
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• 2012

This study was conducted to examine dietary behaviors according to residence status and ethnicity of university students in Yanbian, China. For the subjects, 334 university students (Male=141, Female=193) answered a questionnaire about perception of weight control, dietary patterns, health habits, residence status, and ethnicity. Perception of weight, meal frequency, favorite kind of food, meal finishing time, skipping breakfast, type of breakfast, snack frequency, late-night snack frequency, exercise frequency, regular life, and sleeping time were all significantly associated with residence status. Motivation of weight control, meal frequency, regularity of meal time, meal volume, favorite kind of food, exercise time, and regular life were all significantly associated with ethnicity. University students who lived with their parents perceived their weight more properly, exhibited a more positive dietary pattern, and lived a more regular life than those students who lived in a dormitory with their friends. Chinese students exhibited a more regular dietary pattern and lived a more regular life than the Korean-Chinese students. As a result, both environmental and inherent factors are related with the dietary behaviors of university students in Yanbian, China. These data could be used to help university students in Yanbian, China attain a healthy diet.

• 치위생과학회지
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• 제7권3호
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• pp.179-185
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• 2007

본 연구는 대구광역시에 소재한 인문계, 실업계 남자 고등학생들을 대상으로 청소년기의 측두하악장애 유병실태와 기여요인, 악안면외상 경험과 관리 실태, 고교별 측두하악장애와 학교생활에서의 스트레스와의 관계를 관찰함으로서 측두하악장애의 예방과 치료에 있어 적절한 인식과 구강보건교육프로그램개발에 필요한 기초 자료를 마련하고자 본 연구를 시도하여 다음과 같은 결과를 얻었다. 1. 남자고등학생에서 측두하악장애의 유병률은 61.8%에서 관절잡음을 경험하였고, 관절탈구 6.9%, 저작시동통 47.5%, 비저작시동통 29.8%, 개구장애 11.3%, 두통이 40.4%로 나타났다. 2. 측두하악장애를 일으키는 기여요인에서 관절잡음은 이악물기, 입술 뺨깨물기, 저작시동통에서는 이악물기, 이갈이, 편측저작, 과잉저작, 입술 뺨깨물기, 모로취침 등이 유의한 차이를 보였다(P < 0.01). 비저작시동통은 이악물기, 이갈이, 편측저작, 입술 뺨깨물기 개구장애는 이악물기, 이갈이, 모로취침에서 통계적으로 유의한 차이를 보였다(P < 0.01). 두통은 모로취침을 제외한 나머지 항목에 대한 악습관이 측두하악장애의 기여요인으로 나타났다(P < 0.01, P < 0.05). 3. 측두하악장애를 일으킬 수 있는 악안면외상 경험률은 인문계고 19.6%, 실업계고 13.4%였고, 외상 요인으로 인문계고는 운동 26.8%, 기타 24.4%, 넘어짐 19.5%순이였으며, 실업계고는 운동 44.4%, 넘어짐 22.2%, 기타 14.9%순이었다. 치료경험은 인문계고 있다 2.9%, 실업계고 5.0%로 나타났으며 치료기관으로는 인문계고 치과 50%, 정형외과 50%, 실업계고 정형외과 40%, 한의원 30%, 치과 30%로 나타났다. 4. 측두하악장애는 학년별, 학력수준별 유의한 차이는 없었고, 인문계고와 실업계고의 측두하악장애 정도에서 저작시동통, 비저작시동통은 유의한 차이를 보였다(P < 0.01). 5. 고교별 학교에서의 스트레스를 비교해보면 성적 및 학업문제로 인해 인문계고 $3.75{\pm}1.14$, 실업계고 $3.01{\pm}1.23$로 전반적으로 실업계고 보다는 인문계고에서 스트레스 정도가 높게 나타나 유의한 차이를 보였다. 6. 성적 및 학업의 문제, 학교생활문제, 교사와의 문제로 인한 스트레스와 측두하악장애의 저작시동통, 비저작시동통, 관절잡음은 유의한 상관관계를 보였다(P < 0.01, P < 0.05).

• 한국산학기술학회논문지
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• 제13권3호
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• pp.1203-1211
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• 2012

본 연구의 목적은 직업유무에 따라 노인의 건강상태, 수면 및 우울을 비교하고, 건강상태와 수면이 우울과 관련이 있는지를 파악하는 것이다. 본 연구는 보건복지가족부가 실시한 "2008 노인실태조사"의 자료를 사용하였으며, 총 조사대상자 15,146명 중 직업이 있는 노인 5,204명과 직업이 없는 노인 9,942명이 최종분석에 이용되었다. 연구결과에 따르면 직업 유무에 따라 건강상태, 수면 및 우울에 유의한 차이가 있었다. 직업이 있는 노인의 경우 직업만족도가 우울에 가장 큰 영향을 미치는 요인으로 나타났으며, 주관적 건강상태, 현재 질병으로 인한 일상생활의 어려움 정도, 숙면을 취한 일수 순서로 유의한 영향을 미치는 것으로 나타났다. 이 변수들의 우울에 대한 설명력은 29%로 나타났다. 직업이 없는 노인의 경우 주관적 건강상태가 우울에 가장 큰 영향을 미치는 것으로 나타났으며, 현재 질병으로 인한 일상생활의 어려움 정도, 숙면을 취한 일수, 총 수면 시간 순으로 우울에 유의한 영향을 미치는 것으로 파악되었다. 이 변수들의 우울에 대한 설명력은 32%로 나타났다. 그러므로 노인의 건강상태, 수면, 우울을 향상시키기 위한 건강증진 중재는 직업유무에 따른 이러한 차이를 고려하여 계획되고 제공되어야 한다.

• 지역사회간호학회지
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• 제9권1호
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• pp.40-63
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• 1998

A long life is the desire of many people. The purpose of this study was to describe long life factors for people aged one hundred and above on Chju island. The research was conducted using a phenomenological method to add understanding to this subject. The field work for this study was done from July, 1997 to February, 1998 on Cheju island. The sample consisted of 10 persons of one hundred or above and 12 families. They were audio-recorded and analyzed using Colaizzi's (1978) method. The results of the present study shows the following: The thoughts of the persons one hundred and above showed ten important concepts; 'dietary regimen', 'mental regimen', 'sleep regimen', 'residence regimen', 'health regimen', 'labor regimen', 'exercise regimen', 'being born', 'filial piety and posterity', 'attachment to life'. Concerning 'Dietary Regimen': Dietary regulation, Preferential food intake, Living on vegetables, Light eating, and concern for longevity in food intake were important. Concerning 'Mental Regimen' : Harmony, Clearheadedness, Mildness, Abstinence, Generosity, Relaxation, Gaiety, Inspiration and Strength were important. Concerning 'Sleep Regimen'; Enough sleeping hours, Sound sleep, Curved sleeping posture, and Comfortable bedding were important. Concerning 'Residence Regimen' ; Clean dwelling, Pleasant surroundings, Thatched house life, Living in the village with good-hearted people, and Regular life were important. Concerning 'Health Regimen'; Temperance of drug, use Proper temperature, Proper humidity, and a Clean body were important. Concerning 'Labor Regimen'; Agricultural labor, Diligence, and Domestic labor were important. Concerning Exercise Regimen': Proper exercise, and Sunbathing were important. Concerning 'Being Born' ; Strong physical constitution, Longevity lineage, and Destiny were important. Concerning 'Filial Piety and Posterity' : Showing respect to a long-lived elder and Reducing anxiety were important. Concerning 'Attachment to Life' ; The desire to live long was important. The following conclusion was made from the above results. Human beings cannot avoid death, but the span of life can be prolonged to the maximum span of human life by wisdom, health care, and proper environmental conditions. As a result, a health regimen must be imposed for longevity such as controling food intake, having positive thoughts, being relaxed, sleeping enough, clean dwelling, taking care of oneself which can improve immunity and resistance to decrease, as well as proper labor and exercise. In addition, when filial piety is served, the desire of longevity and retaining one's youthfulness for a long time can be achieved. These should be done to live long and lead a qualitative life. By the results of this research, the following is suggesed for nursing. To satisfy the basic nursing principle that nursing must be practiced to help people live long, education must be spread to people who are nursed and their family so that they can lead a healthy life. And in nursing elders, nurses must recognize that elders have a strong desire for life, even though they may have negative thoughts about life at times. Therefore nurses have to respect the elders' value of life, and help them improve their self-esteem and self -fulfilment.

• 동의신경정신과학회지
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• 제21권1호
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• pp.89-108
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• 2010

Objectives: This study was to investigate the relation of Pittsburgh Sleep Quality Index(PSQI) and Diagnos system of oriental medicine(DSOM) in the Insomnia Patients. Methods: For this study, we carried out PSQI and DSOM of 92 patients with insomnia who have come to Kijang public health center and Donguei oriental hospital of Donguei university from November 2008 to October 2009. We verified the association of PSQI and DSOM using crosstabulation analysis, independent sample T-test, one-way ANOVA and correlation analysis. Results: 1. Blood-deficiency(血虛) is the most frequent pathogenic factor and frequency of nightmare has positive correlation with that factor including heart(心) in total insomnia patients. 2. Female patients have a higher percentage of chronic insomnia than male patients. 3. As patients aged, maintaining sleep gets harder, sleep time is lessening, taking hypnotics is increasing and quality of sleep gets worse. 4. There is high frequency of chronic insomnia in 40~50 years and over 60 years old. Also, the people who are over 60 years of age tend to sleepless and urinated frequently during the middle of the night. The people with the age of 20~30 years tend to take less sleeping pills and frequency of sleeping during daytime is higher than the other age groups but the quality of sleep is quite good. 5. The patient with over 6 months of chronic insomnia tend to be older in age than the patient with less than 6 months. And the patient with chronic sleeping disorder has frequent pain and the quality of sleep is very poor. 6. The patient who took hypnotics tend to be older than hypnotics non-user and frequency of urination was relatively high. 7. The patient who visited oriental medical hospital were tend to be older and get difficult in maintaining sleep. And frequency of taking hypnotics and urinating during night were tend to be higher and the quality of sleep was poor compared with the patient who visited public health center. Conclusions: This study provides insights into the complicated relations of the associated symptom of insomnia with Diagnos system of oriental medicine. And especially this study showed apparent correlation between nightmare in insomnia patients and pathogenic factor of blood-deficiency and heart. Specific correlations and characteristics in this study could be connect develop of new questionaire of insomnia.

• Journal of Oral Medicine and Pain
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• 제43권2호
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• pp.27-33
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• 2018

Purpose: Many researchers have established a connection between sleep disturbances and the symptoms of temporomandibular disorder (TMD) in adults, but there are a few studies targeted at adolescents with TMD. The aim of this study was to analyze the sleep pattern of adolescents with TMD and to determine the effect of poor sleep quality on their clinical symptoms. Methods: The subjects were composed of 47 adolescents with TMD. The sleep pattern and preliminary information of patients were measured by self-reported questionnaires; Pittsburgh Sleep Quality Index (PSQI) and Questionnaire for TMD analysis. TMD pain was scored using the Numerical Rating Scale. The Kruskal-Wallis test, Mann-Whitney U test, Fisher's exact test and logistic regression were used for statistical analysis. Results: The poor sleeping group had statistically more females (25.00% males, 75.00% females) than the good sleeping group. As compared with that of good sleepers, sleep quality of poor sleepers was significantly worse in the items of subjective sleep quality, sleep latency, sleep duration, sleep disturbances, daytime dysfunction and global PSQI score. The sleep time of adolescents was much longer during vacation ($7.20{\pm}1.38hours$) than during school days ($6.10{\pm}1.26hours$). Poor sleep of patients was associated with the pain in the ear or in front of the ear, in the face, jaw, throat or temple and in neck or back. Adolescents with pain in those areas had significantly higher proportion of poor sleepers than adolescents with no pain in those areas. Conclusions: The high ratio of girls in poor sleeping group could reflect the greater prevalence of TMD in women than in men. Pain in peri-temporomandibular joint areas, neck or back could negatively influence sleep quality of adolescents with TMD.