• Journal of Korean Medicine Rehabilitation
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• v.32 no.1
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• pp.73-87
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• 2022

Objectives We aimed to characterize the results obtained from Korean medical examinations and questionnaires on the quality of sleep. Methods The quality of sleep was measured using the Pittsburgh sleep quality index in 400 subjects. Afterwards, heart rate variability (HRV) measurements were done, along with the analyses for tongue color, teeth marks, and tongue coating through the tongue diagnosis system. A questionnaire about body's heat, cold and sweating conditions, and the perceived stress scale (PSS) were performed. Finally, correlations between all these indicators and the sleep quality were analyzed. Results As the quality of sleep decreased, the sympathetic nervous system was stimulated. The subjects who had the blue-purple colored tongue experienced decreased quality of sleep. The quality of sleep was also deteriorated in the subjects who usually feel cold and hot easily, sweat a lot, and feel a lot of discomfort. According to the PSS questionnaire, the higher the stress level is, the lower was the quality of sleep. Conclusions We obtained meaningful results by comprehensively analyzing the sleep quality, HRV, tongue diagnosis, heat and cold conditions, sweating, and stress conditions. In particular, the sleep quality had a significant correlation with the rest of the indicators.

• Sleep Medicine and Psychophysiology
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• v.9 no.2
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• pp.86-95
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• 2002

Various sleep-related problems are common in pregnant women. Sleep disorders may result in intrauterine growth restriction as well as harm to pregnant women. Pharmacotherapy of sleep disorders in pregnancy require cautious judgement. All physicians managing sleep-related problems of pregnant women in clinical practice need to understand sleep-related problems and their management in pregnancy. Therefore, I have reviewed the literature on normal sleep, sleep disorders and their management in pregnancy.

• Sleep Medicine and Psychophysiology
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• v.3 no.2
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• pp.77-89
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• 1996

Data collected to date indicate that sleep apnea syndrome is a risk factor in the development of cardiovascular dysfunction such as systemic hypertension, cardiac arrhythmias, pulmonary hypertension, right heart failure, angina, myocardial infarction, and stroke. Several reports suggest that untreated patients with sleep apnea syndrome have a higher long-term mortality than treated patients and than normal subjects. But there are many controversies concerning the treatment of sleep apnea syndrome, and there is no universally accepted standard for effective treatment. We reviewed the current approaches and options in the medical treatment of sleep apnea syndrome.

• Journal of Sasang Constitutional Medicine
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• v.16 no.2
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• pp.52-57
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• 2004

1. Objectives In ShinChukbon "DongyiSuseBowon", there are many contents of constitutional diseases and symptoms. The aim of the present study was to investigate recognition of sleep as Dong-Mu's constitutional symptoms. 2. Methods In ShinChukbon "DongyiSuseBowon", I found contents about sleeping and made comparative study of acquired contents. And I made comparative of previous studies. 3. Results (1) I concluded that Soumin who has interior and exterior diseases didn't get sleep well. Under the condition that constitutional diseases are cured, Soyangin gets to sleep well. (2) I concluded that Soyangin who has interior and exterior diseases sleep lesser than ordinary symptoms. Under the condition that constitutional diseases are cured, Soyangin gets to sleep well. (3) I concluded that Taeumin who has interior diseases sleep lesser than ordinary symptoms. Under the condition that constitutional diseases are cured, Taeumin gets to sleep well. (4) I concluded that Taeang who has constitutional disease may sleep lesser than ordinary symptoms. But not confirmed. 4. Conclusions There is some ground that sleep as constitutional symptom would be a good authority of checking constitutional disease.

• Sleep Medicine and Psychophysiology
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• v.19 no.1
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• pp.5-10
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• 2012

The release of hormones and the metabolism of human body are controlled by the circadian rhythm related to sleep-wake cycle. Growth hormone, prolactin, thyroid stimulating hormone, cortisol, glucose, and insulin-secretion rates fluctuate according to the sleep-wake cycle. In addition, sleep is related to the appetite regulation and carbohydrate and other energy metabolism. Hypocretin (orexin), an excitatory neuropeptide, regulates waking and diet intake, and the poor sleep increases diet intake. The short sleep duration increases one's body mass index and impairs the function of the endocrine and metabolism, causing increases in the risk of glucose intolerance and diabetes. The poor sleep quality and sleep disorders have similar impact on the metabolic function. In short, the sleep loss and the poor quality of sleep have a detrimental effect on the endocrine and energy metabolism. The improvement of sleep quality by the future research and appropriate clinical treatment would contribute to the decrease of the metabolic diseases such as diabetes.

• Sleep Medicine and Psychophysiology
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• v.19 no.2
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• pp.59-62
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• 2012

Borderline personality disorder (BPD) is characterized by identity and interpersonal problem, affective dysregulation and pervasive severe impulsivity. Although sleep disturbances are not primary symptoms of BPD, they are important aspects of this disorder. However, clinicians and researchers did not give much attention to the sleep symptoms of BPD yet. Measured by nocturnal polysomnography, increased sleep latency as well as reduced total sleep time and sleep efficiency, and 'depression-like' REM abnormalities (i.e., reduced REM latency and increased REM density) are found in BPD patients. Co-morbid sleep disorders such as chronic insomnia, nightmare disorder or circadian rhythm sleep disorder associated with BPD have been reported. Clinicians should focus on the sleep complaints of BPD patients, and carefully manage such symptoms with sleep hygiene education, cognitive psychotherapy or light therapy.

• Sleep Medicine and Psychophysiology
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• v.5 no.1
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• pp.18-33
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• 1998

Sleep and Epilepsy either represent the opposite and independent spectrum of episodic manifestations from brain or closely interact with each other. Sleep or sleep deprivation may provoke epileptic seizures or activate epileptiform discharges in epilepsy patients whereas epilepsy may alter the sleep structure. Sleep stages are also known to influence pathophysiology of seizures in terms of ictogenesis. In this review, the impact of sleep on epilepsy as well as that of epilepsy on sleep are presented. Additionally the interaction between sleep and epilepsy will be discussed. This review will also comment on the differential diagnosis between nocturnal or sleep-related epilepsy and various sleep disorders. Finally, clinical application of the above perspectives of sleep and epilepsy will be suggested for the purpose of a better management of epilepsies.

• Sleep Medicine and Psychophysiology
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• v.27 no.2
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• pp.33-40
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• 2020

An infant's sleep varies considerably from that of adults in terms of structure, amount, and breathing pattern. After birth, sleep becomes evenly distributed throughout the day and night. Nighttime sleep gradually increases with the maturation of circadian rhythm, and sleep is gradually consolidated. Electroencephalography characteristics change with age, from early and dominant active (REM) sleep in newborns to increasing NREM sleep. Similar to other elements of growth, the upper respiratory tract and ribcage gradually increase in size with age, and respiratory control also improves. With these changes, sleep patterns also change. At this time that various sleep disorders may appear. Improved understanding of age-dependent changes in infant sleep can help determine the etiology and facilitate diagnosis of infant sleep diseases.

• Journal of Sasang Constitutional Medicine
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• v.29 no.1
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• pp.40-49
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• 2017

Objectives Sleep duration and sleep quality are closely related to obesity, however there are few studies considering the Sasang constitution. This study is to investigate the relationship between sleep status and obesity according to Sasang constitution. Methods This cross-sectional research studied 2,672 participants (1,293 men and 1,379 women) using the Korean Medicine Data Center (KDC) of the KIOM. Sasang constitution was diagnosed by KS-15 questionnaire. Obesity was divided into two categories: general obesity was defined as Body Mass Index(BMI) ${\geq}25kg/m^2$, and abdominal obesity was defined as waist circumference ${\geq}90cm$ in men and ${\geq}85cm$ in women. Sleep quality was assessed using the Pittsburgh Sleep Quality Index. Results The distribution of the subjects was 56.9% for Taeumin and 43.1% for non-Taeeumin., Poor sleep quality increased both BMI and waist circumference in Taeeumin. In men Taeeumin, sleep duration was correlated with BMI, and sleep quality was correlated with waist circumference. The prevalence of obesity was significant difference according to sleeping duration in men Taeeumin, it was the highest at 6 hours of sleeping time. Conclusions Sleep duration and sleep quality was associated with obesity in Taeeumin. Especially, in men Taeeumin, adequate sleep duration was an important factor for prevention and treatment of obesity.

• Sleep Medicine and Psychophysiology
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• v.6 no.1
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• pp.19-25
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• 1999

Sleep alters both breathing pattern and the ventilatory responses to external stimuli. These changes during sleep permit the development or aggravation of sleep-related hypoxemia in patients with respiratory disease and contribute to the pathogenesis of apneas in patients with the sleep apnea syndrome. Fundamental effects of sleep on the ventilatory control system are 1) removal of wakefulness input to the upper airway leading to the increase in upper airway resistance, 2) loss of wakefulness drive to the respiratory pump, 3) compromise of protective respiratory reflexes, and 4) additional sleep-induced compromise of ventilatory control initiated by reduced functional residual capacity on supine position assumed in sleep, decreased $CO_2$ production during sleep, and increased cerebral blood flow in especially rapid eye movement(REM) sleep. These effects resulted in periodic breathing during unsteady non-rapid eye movement(NREM) sleep even in normal subjects, regular but low ventilation during steady NREM sleep, and irregular breathing during REM sleep. Sleep-induced breathing instabilities are divided due primarily to transient increase in upper airway resistance and those that involve overshoots and undershoots in neural feedback mechanisms regulating the timing and/or amplitude of respiratory output. Following ventilatory overshoots, breathing stability will be maintained if excitatory short-term potentiation is the prevailing influence. On the other hand, apnea and hypopnea will occur if inhibitory mechanisms dominate following the ventilatory overshoot. These inhibitory mechanisms include 1) hypocapnia, 2) inhibitory effect from lung stretch, 3) baroreceptor stimulation, 4) upper airway mechanoreceptor reflexes, 5) central depression by hypoxia, and 6) central system inertia. While the respiratory control system functions well during wakefulness, the control of breathing is commonly disrupted during sleep. These changes in respiratory control resulting in breathing instability during sleep are related with the pathophysiologic mechanisms of obstructive and/or central apnea, and have the therapeutic implications for nocturnal hypoventilation in patients with chronic obstructive pulmonary disease or alveolar hypoventilation syndrome.