• Title/Summary/Keyword: sleep loss

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Congenital LQT Syndromes: From Gene to Torsade de Pointes

  • Carmeliet, Edward
    • The Korean Journal of Physiology and Pharmacology
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    • v.6 no.1
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    • pp.1-7
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    • 2002
  • Congenital Long QT syndrome (LQTs) is a relatively rare pathologic disorder but results frequently in sudden cardiac death. Of the six LQTs that have been clinically described, five have been worked out for their genetic and biophysical profile. Most are generated by mutations which cause a loss of function in two delayed $K^+$ currents, $i_{Ks}\;and\;i_{Kr}.$ One syndrome is generated by mutations in the $Na^+$ channel which causes essentially a gain of function in the channel. Clinically the syndromes are characterized by slowed repolarization of the cardiac ventricular action potential and the occurrence of typical arrhythmias with undulating peaks in the electrocardiogram, called Torsade de Pointes. Arrhythmias are initiated by early or delayed afterdepolarizations and continue as reentry. Triggers for cardiac events are exercise (swimming; LQT1), emotion (arousal; LQT2) and rest/sleep (LQT3). ${\beta}-blockers$ have a high efficacy in the treatment of LQT1 and LQT2. In LQT3 their use is questionable. The study of congenital LQTsyndromes is a remarkable example of how basic and clinical science converge and take profit of each other's contribution.

A Case Report of Intractable Hiccups after Laparoscopic Cholecystectomy (복강경 담낭절제술 후 발생한 난치성 딸꾹질 환자 증례)

  • Shin, Cho-Young;Jung, Hye-Mi;Hwang, Min-Young;Kim, Sol-Li;Yoon, Cheol-Ho
    • The Journal of Internal Korean Medicine
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    • v.31 no.4
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    • pp.901-907
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    • 2010
  • Hiccups are defined as abrupt involuntary contractions of diaphragm and intercostal muscles with sudden closure of the glottis. Hiccups are one of the common transient symptoms but when hiccups last more than 48 hours, or have no response to treatment, they are defined as intractable hiccups. Intractable hiccups can induce multiple problems such as weight loss, dehydration and sleep disturbance. We report a 76-year-old male patient who suffered from intractable hiccups for 6 days after laparoscopic cholecystectomy. Hiccupping was so severe as to continue all day long and limit sleeping and eating. We succeeded in cure intractable hiccups with acupuncture and herbal formula; Gyulyeohwadam-tang.

Ultrasound-guided Pulsed Radiofrequency Lesioning of the Phrenic Nerve in a Patient with Intractable Hiccup

  • Kang, Keum-Nae;Park, In-Kyung;Suh, Jeong-Hun;Leem, Jeong-Gill;Shin, Jin-Woo
    • The Korean Journal of Pain
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    • v.23 no.3
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    • pp.198-201
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    • 2010
  • Persistent and intractable hiccups (with respective durations of more than 48 hours and 1 month) can result in depression, fatigue, impaired sleep, dehydration, weight loss, malnutrition, and aspiration syndromes. The conventional treatments for hiccups are either non-pharmacological, pharmacological or a nerve block treatment. Pulsed radiofrequency lesioning (PRFL) has been proposed for the modulation of the excited nervous system pathway of pain as a safe and nondestructive treatment method. As placement of the electrode in close proximity to the targeted nerve is very important for the success of PRFL, ultrasound appears to be well suited for this technique. A 74-year-old man suffering from intractable hiccups that had developed after a coronary artery bypass graft and had continued for 7 years was referred to our pain clinic. He had not been treated with conventional methods or medications. We performed PRFL of the phrenic nerve guided by ultrasound and the hiccups disappeared.

Experience of Frailty in Korean Elderly: A Phenomenological Study Utilizing the Colaizzi Method (한국 노인의 허약 경험: Colaizzi의 현상학적 방법으로)

  • Park, Jin Kyoung
    • Journal of Korean Academy of Nursing
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    • v.47 no.4
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    • pp.562-574
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    • 2017
  • Purpose: This study attempts to explore the subjective experience of frailty among elderly individuals in Korea. Methods: From June to August in 2014, 11 elderly persons who had experienced frailty in a community were interviewed. For data analysis, the method suggested by Colaizzi was applied as a phenomenological method. Results: According to the analysis, the study participants' frailty process was structured in seven categories: (a) 'natural phenomenon with ageing,' (b) 'life force comes to an end,' (c) 'the light in my heart turns off,' (d) 'unavoidable situation,' (e) 'continuous and connected vicious cycle,' (f) 'the limit of recovery energy already passes,' and (g) 'life is supported by someone's help.' Conclusion: The frailty experience in the participants is a natural process of aging, which cause vicious cycle acting with each other among physical, psychological, and social health. It is said that the cycle of frailty was started from weight loss and insufficient sleep, and boostered by pain. The participants from repetition of the vicious cycle become exhausted and pass the threshold of their recovery energy at some points. If they meet with sudden accidents such as falling, traffic accident and so on, they become to live a dependent life supported by someone's help in a moment. To prevent frailty and worsening conditions in Korean elderly individuals, it is recommended to provide a interventional programs using this study's results.

A Survey Study on Characteristics Associated with Fractures in Elderly People (노인골절 환자의 골절 관련 특성에 대한 연구)

  • Lee Jong-Kyung
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.10 no.3
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    • pp.326-334
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    • 2003
  • Purpose: The purpose of this study was to identify characteristics associated with fractures in elderly people in order to provide basic data for fracture preventive programs for the elderly people. Method: The participants were 84 patients over age of 65, who were admitted to the orthopedic department in a hospital in Chungnam province. Data were collected from Sep. 1, 2002 to Aug, 30, 2003 through personal interviews using a structured questionnaire. The data were analyzed using SPSSPC program. Result: Physical characteristics before the fracture included weakness or paralysis in the extremities (29.8%), need of assistance or appliances (13.1%), difficulty on balance (28.6%), visual disturbances (26.2%), hearing impairment (17.9%), speech disturbances (2.4%), urinary dysfunction (21.4%), and sleep disturbances (54.8%). The fractures occurred most frequently in winter (32.1%), between 1 pm and 6 pm (48.8%), on weekends (41.6%), in the road (58.3%) while wearing snickers (27.4%) or shoes (27.4%). The region of fractures occurred most frequently was lower extremities (57.1%), and the causes of fractures were loss of balance (31.0%) and car accident (25.0 %). A significance difference was found for type of accident, footwear at the time of the accident, place of the accident according to gender and age. Also a significance difference was found for type of accident and place of accident according to season(p<.05). Conclusion: Therefore, these results should be considered when a fracture preventive program for elderly people is designed.

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A study on conditions for stroke patient & Analysis of effect after exercise treatment (뇌졸중 발병전·후의 생활·운동에 따른 비교)

  • Baek, In-Hyeob;Koh, Jae-Moon
    • The Korean Journal of Emergency Medical Services
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    • v.5 no.1
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    • pp.109-131
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    • 2001
  • 1. In general, male-to-female rate of those investigated was 1.83:1(M:F) and in term of economic status, most were middle class. The investigation shows that reserved, sharp and nervous persons were inclined to easily fall ill. 2. The probability of their falling ill was high in the fall and during sleep because probability of cerebral infarction was high. 3. It was found that they more refained from overeating and from eating pungent food and had less meat than before illness, in addition that refaining from drinking and smoking further improves their daily lives. 4. The especially acknowledged the necessity of physical exercise, they exercised, more frequency, but less strenuously. This was due to the decline in their physical strength or the unsystematic nature of the exercise. 5. In terms of weight loss, the test subjects lost 5kg on average while two of them lost 10kg. The investigation revealed that such stroke patients could overcome a range of problems, and they could improve and maintain their daily condition through guidance and education about their illness. Furthermore, it was revealed that patients needed be shown love and concern, to lead a normal satisfying social life.

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A Study on the Optimal Flight Time According to the Amount of Fatigue (피로누적에 따른 최적 비행시간 산출에 관한 연구)

  • 이승훈;윤봉수
    • Journal of the military operations research society of Korea
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    • v.24 no.1
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    • pp.41-57
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    • 1998
  • Since the aircraft has a property of moving in the three-dimensional space, it may cause personally and financially critical damage in the case of an accident. Among the causes of aircraft accident, human factor has occupied about 70% of all accidents. Specially, fatigue among human's problems has been studied earlier than any other factor. Fatigue has been the cause of 75% of accidents that are related to human factor. So many studies have been conducted. But the direction of these studies mainly attach importance to the sleep loss and circadian rhythm. Limitation for flight time of ICAO is 8 hours per day, civil airlines in domestic line also adopt the limitation. But this rule is not based on human's performance but compromise between labor and management. The long-haul flight brings about a mental block to pilot. This mental block decreases performance of pilot and loses a lot of important information. So this may cause many accidents. This paper is to offer optimal flight time according to the amount of fatigue due to increasing flight time. The optimal flight time is searched through the field experiment. The experiment has adopted two methods. One is to examine pilot's objective fatigue accumulation rate through the critical fusion frequency, and another is to investigate pilot's subjective fatigue feeling through the fatigue subjective symptoms investigation table.

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Study on Male Chronic Fatigue in Hyungsang Medicine (남자 만성피로의 형상의학적 고찰)

  • Park, Tae-Sook;Lee, Yong-Tae
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.3
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    • pp.605-611
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    • 2005
  • Chronic fatigue refers to the tiredness which disturbs one's daily activities and lasts more than six months without the sign of improvement by rest or sleep. Male chronic fatigue is included in internal injuries due to overstrain and exhaustion and closely related to river, spleen, stomach and kidney out of five Jang organs. Male chronic fatigue is based on the deficiency of Yang and aggravated by liquor, sex and emotional depression. Chronic fatigue has the following features in Hyungsang ; an inclination for lying: unwillingness to everything; drooping eyes and feeble voice; yellow pale complexion; withered ears; redness on the tip of nose; cheekbone, and lips; blood shot eyes; dryness and loss of hair. Male chronic fatigue usually attacks the persons of horse type and bird type because they are hyperactive compared with what they eat. The following medicines are commonly prescribed for the treatment of male chronic fatigue. Ssangwhatang, Sokunzungtang, and Yanghyulsamultang are commonly prescribed to horse type. Jaumkangwhatang, Chungsimyunzaum, Yookmijiwhangtang to bird type. Palmiwhan, Gozinumja. and Shinkihwan to fish type. Bozungikkitang, Galwhahaesungtang, Samchulgunbitang and Sipjundaebotang to turtle type.

6 Cases of Atopic Dermatitis Female Adolescent Patients for Hospitalization Program (캠프 형식의 입원 치료를 받은 여중생 아토피피부염 환자 6례)

  • Oh, Jin-Ah;Shin, Mi-Ran
    • Journal of Sasang Constitutional Medicine
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    • v.27 no.4
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    • pp.404-418
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    • 2015
  • Objectives This study investigated the effect of camping style Hospitalization program for atopic dermatitis female adolescent patients. 6 patients, 12-14 year old female adolescent, admitted for camping style hospitalization program.Methods 6 patients were admitted for camping style hospitalization program (2014.08.13~2014.08.16). The program included acupuncture, herbal medicine, examination, education, psychotherapy, dressing, exercise. The patients were analyzed by Severity Scoring Atopic Dermatitis(SCORAD) index and measured skin pH value(pH). Also, patients evaluated themselves by writing an atopic dermatitis diary which consists of diet, emotion, severity of pruritus, and sleep loss, and checked questionnaires which consist of atopic dermatitis, self treatment methods and degree of satisfaction of each program.Results Most of subjective symptoms which patients complained were improved and also SCORAD index total scores were decreased by sasang constitutional medication.Conclusions We expect that the camping style hospitalization program based on sasang constitutional medicine could be helpful for female adolescent patient of atopic dermatitis.

Energy-efficient Multicast Algorithm for Survivable WDM Networks

  • Pu, Xiaojuan;Kim, Young-Chon
    • Current Optics and Photonics
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    • v.1 no.4
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    • pp.315-324
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    • 2017
  • In recent years, multicast services such as high-definition television (HDTV), video conferencing, interactive distance learning, and distributed games have increased exponentially, and wavelength-division multiplexing (WDM) networks are considered to be a promising technology due to their support for multicast applications. Multicast survivability in WDM networks has been the focus of extensive attention since a single-link failure in an optical network may result in a massive loss of data. But the improvement of network survivability increases energy consumption due to more resource allocation for protection. In this paper, an energy-efficient multicast algorithm (EEMA) is proposed to reduce energy consumption in WDM networks. Two cost functions are defined based on the link state to determine both working and protection paths for a multicast request in WDM networks. To increase the number of sleeping links, the link cost function of the working path aims to integrate new working path into the links with more working paths. Sleeping links indicate the links in sleep mode, which do not have any working path. To increase bandwidth utilization by sharing spare capacity, the cost function of the protection path is defined to use sleeping fibers for establishing new protection paths. Finally, the performance of the proposed algorithm is evaluated in terms of energy consumption, and also the blocking probability is evaluated under various traffic environments through OPNET. Simulation results show that our algorithm reduces energy consumption while maintaining the quality of service.