• Korean Journal of Human Ecology
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• v.18 no.2
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• pp.501-507
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• 2009

Atopic dermatitis is one of the most common skin disease in children and a characteristic chronically recurrent form of dermatitis with a hereditary tendency, affecting infants and may extend to the childhood or th the adult age. Environmental factors, stress, and foodstuffs such as milk, egg may cause atopic dermatitis. Nc/Nga mice were used as an animal model for human atopic dermatitis. The divided by 4group such as normal group, BMAC group, FK506 group, MR group for this study raised in conventional conditions. To investigate effect of Chamomile German on atopic dermatitis in NC/Nga mice, the serum IgE and IgG1 level were measured while the severity degree of the skin lesion was examined by the naked eyes of two volunteers who were unaware of the treatment status. The results were the followings. 1. The score on the severity degree of skin dermatitis in FK 506 and MR group was lower than that in control group. 2. The serum IgE level in control group was higher 25% than that in normal group. 3. The serum level of IgE in FK506 and MR group compares to control group was decreased. 4. The serum IgG1 level was decreased more than 3.5 times in FK506 compared to control group while MR group had significantly less the serum IgG1 than control group. From the above results, treatment of Chamomile German oil had the effect on atopic dermatitis in NC/Nga mice. If scientific researches on aroma oil are performed in various way, aroma oil will be used to cure skin dermatitis as a alternative therapy in the future.

• CELLMED
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• v.10 no.2
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• pp.15.1-15.9
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• 2020

Introduction: Buthūr Labaniyya (Acne vulgaris) is a multifactorial disorder of the pilosebaceous units characterized by non-inflammatory and inflammatory clinical lesions. Several Unani medications have been used for centuries to treat acne. Objectives: Evaluation of safety and efficacy of Tila-i Muhāsā in patients with acne vulgaris Materials and Methods: This clinical study was conducted in patients with acne vulgaris. Patients applied Tila-i Muhāsā or 5% Benzoyl Peroxide (BPO) once daily for 6 weeks. Assessment of efficacy was carried out by Global Acne Grading System (GAGS) and Patient Global Assessment (PGA) scores. In addition, overall severity of acne was evaluated on a 5-point Cook's acne grading scale using photographic standards. Assessment of safety was performed through adverse drug reactions, local dermal tolerability, vital signs, and routine laboratory investigations. Results: A total of 60 patients (30 in each group) completed 6 weeks of treatment. The mean percentage reduction in GAGS score at 6 weeks from baseline in Unani group (66.97%) and BPO group (59.09%) was statistically significant (P<0.0001). After 6 weeks of therapy, the mean percentage reduction in PGA score compared to baseline in Unani group (57.44%) and BPO group (50.23%) was statistically significant (P<0.0001). No serious adverse events were reported in both groups; however, mild adverse events occurred more frequently in BPO group (30%) compared to Unani group (10%). Conclusion: Tila-i Muhāsā was found to be effective and safe in the treatment of acne vulgaris. However, further clinical studies with larger sample size and longer duration of therapy need to be conducted.

• The Journal of Korean Medicine
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• v.36 no.4
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• pp.104-113
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• 2015

A 56-year-old Korean female patient developed generalized morphea over three months. We focused on imbalance of the neuroendocrine-immune axis, mainly using Jiawei-Renshengyangrong-tang and Jiawei-Siqi-tang. Moxibustion on LU9 was conducted for skin symptoms. The patient's modified localized scleroderma skin severity index score decreased from 22 to 6 over 22 weeks of treatment and to 4 during a 3-month follow-up. Her verbal rating scale score for general symptoms decreased from 17 to 1 during the 22-week treatment.

• Journal of Microbiology and Biotechnology
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• v.25 no.11
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• pp.1966-1969
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• 2015

Canine atopic dermatitis (CAD) is a ubiquitous, chronic inflammatory skin disorder prevalent in dogs, which results in production of abnormal levels of IgE antibodies in reciprocation to an allergen challenge. In this study, administration of the probiotic strain Lactobacillus sakei probio-65 for 2 months significantly reduced the disease severity index in experimental dogs diagnosed with CAD. In addition, one month pre-medication of L. sakei probio-65 revealed significant difference in the PVAS score in experimental dogs for both probio-65 and placebo groups. However, post 2 months treatment resulted in a significant decrease in the CASESI score values in the probio-65-treated group (p < .0.06).

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.3
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• pp.251-259
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• 2007

Objective : This study is designed to investigate the effect of Oriental medical therapy on psoriasis. Methods : We applied Aroma ointment to abnormal skin two times a day. For herbal medicine, Bangpungtongsungsan-gami was given. We checked involvement in scaly skin, erythematosus papules and infiltration according to psoriasis area and severity(PASI) Results : After treatment, the patient showed that itching symptoms was disappeared and score of PASI changed from 27 to 0.8 Conclusions : According to the result, Oriental medical therapy and Aroma therapy has a good effect on psoriasis. But further studies are required to definitely prove the effectiveness of Aroma therapy

• Journal of Pharmacopuncture
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• v.23 no.3
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• pp.173-178
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• 2020

Objectives: Atopic dermatitis (AD) is a prevalent and chronic, pruritic inflammatory skin condition that can influence all age groups. AD is associated with a poor health-related quality of life. This randomized clinical trial was performed to compare the effectiveness of Olivederma (combination of aloe vera and virgin olive oil) or betamethasone regarding disease severity, quality of life, serum IgE and eosinophil count. Methods: Thirty-six AD patients were randomly allocated to topical Olivederma or betamethasone, and were followed for 6 weeks. Results: Total SCORAD severity scores showed significant decrease in both groups, while it was more prominent in Olivederma group (64.5% improvement in Olivederma vs. 13.5% improvement in Betamethasone, p-value < 0.001). Quality of life (DLQI questionnaire) of AD patients was significantly improved after 6 weeks treatment with Betamethasone (22.3%, p < 0.001) and Olivederma (60.7%, p-value < 0.001). Olivederma group showed a significantly lower DLQI score in comparison with Betamethasone treated patients after 6 weeks of therapy (p < 0.001). Improvements in eosinophil count and serum IgE was observed. Conclusion: In summary, this study shows that Olivederma is superior to topical Betamethasone after 6 weeks of therapy with regard to disease severity, quality of life and eosinophil count.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.3
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• pp.935-938
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• 2004

Psoriasis is a common skin disease and the difficulty of its medical management is well known, A report was done on psoriaSis which were treated with aroma therapy to be consulted in Dept. surgery, opthalmology & otolarygology, college of Oriental Medicine, Dongeui University, from Dec. 24, 2003 to Mar. 5, 2004. We gave score and checked involvement in plaque, erythematous popules and invasiveness according to psoriasis area and severity index (PASI). After 75 days of treatment the patient showed that symptoms were disappeared and score of PASI changed from 54.7 to 0. These results that Aroma therapy has good effects on psoriasis in assistant therapy.

• The Journal of Pediatrics of Korean Medicine
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• v.26 no.3
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• pp.20-29
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• 2012

Objectives The purpose of this case study is to report the effect of concurrent administration of Danguieumja-gagambang and external treatments on childhood psoriasis. Methods The subject is a child with psoriasis. This patient was treated with oriental herbal medicine (Danguieumjagagambang) and external treatments. The improvement of the skin condition is observed by Psoriasis Area and Severity Index (PASI) score. Results After the treatment, the symptoms of psoriasis were relieved. PASI score of this child went down from 4.7 to 0. Conclusions This study showed that concurrent administration of Danguieumja-gagambang and external treatments can be an effective choice for psoriasis.

• Journal of Korean Medical Ki-Gong Academy
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• v.15 no.1
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• pp.71-88
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• 2015

Objects : The purpose of this case study is to report the effect of Su-Gi therapy with Oriental medical treatments on systemic psoriasis. Methods : The subject is a patient with systemic psoriasis. This patient was treated with Oriental medical treatments and Su-Gi therapy. The improvement of the skin condition is observed by Psoriasis Area and Severity Index (PASI) score. Results : After the treatment, the symptoms of psoriasis were relieved. PASI score of this patient went down from 39.6 to 12.5. Conclusions : This study showed that Su-Gi therapy added with Oriental medical treatment can be an effective choice for systemic psoriasis.

• The Journal of Pediatrics of Korean Medicine
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• v.23 no.3
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• pp.207-216
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• 2009

Objectives The purpose of these 3 cases study is to report the effects of psoriasis children treated by oriental medicine. Methods The subjects are 3 children diagnosed as having psoriasis. These patients were treated by oriental herbal medicine(Bangpungtongsungsan). We observed the improvement of skin condition by Psoriasis Area and Severity Index(PASI) score. Results After treatment, the symptoms of psoriasis were relieved. PASI score of three children in psoriasis was respectively changed from 7 to 0, 2.4 to 0, 3.6 to 0. Conclusions This study shows that Bangpungtongsungsan can be an effective treatment for psoriasis. Further study in needed with more cases of treatment.