• Title/Summary/Keyword: skeletal muscle mass index

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Effects of marine oligomeric polyphenols on body composition and physical ability of elderly individuals with sarcopenia: a pilot study

  • Kwon, Il-Su;Park, Deuk-Su;Shin, Hyeon-Cheol;Seok, Myung-Gyu;Oh, Jae-Keun
    • Korean Journal of Exercise Nutrition
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    • v.25 no.3
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    • pp.1-7
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    • 2021
  • [Purpose] We aimed to identify the effects of marine oligomeric polyphenol (MOP) intake in elderly individuals with sarcopenia. [Methods] Older adults (aged 65 years or older) were recruited based on the diagnostic criterion for sarcopenia and were randomly assigned to the MOP intake group (n=10) or the placebo (PBO) intake group (n=10). To determine the effect of MOP intake received for four weeks, the pre- and post-intake body composition (weight, skeletal muscle mass, and bone density) and senior fitness tests were assessed. [Results] Our results showed there were significant differences in the skeletal muscle mass (p=0.039), bone density (p=0.020), fat-free mass index (p=0.026), and 2.4 m up and go test (p=0.001) between pretest and post-test. There was a significant difference between the pre-test and post-test and an interaction effect for the one-leg stand test (p=0.010 and p=0.049, respectively). However, there were no significant differences in body fat percentage, calf circumference, grip strength, or the chair rise test. [Conclusion] Some variables exhibited significant differences in the pre- and post-assessments, and there was an interaction effect for the one-leg stand. However, this was insufficient to prove the effectiveness of MOP intake in improving sarcopenia. Therefore, additional studies are essential to examine the effects of MOP intake and exercise intervention on the body composition and fitness of patients over a longer period.

Implications of Sarcopenia and Glucometabolism Parameters of Muscle Derived From Baseline and End-of-Treatment 18F-FDG PET/CT in Diffuse Large B-Cell Lymphoma

  • Xiaoyue Tan;Xiaolin Sun;Yang Chen;Fanghu Wang;Yuxiang Shang;Qing Zhang;Hui Yuan;Lei Jiang
    • Korean Journal of Radiology
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    • v.25 no.3
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    • pp.277-288
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    • 2024
  • Objective: We previously found that the incidence of sarcopenia increased with declining glucose metabolism of muscle in patients with treatment-naïve diffuse large B-cell lymphoma (DLBCL). This study aimed to investigate the relationship between sarcopenia and muscle glucometabolism using 18F-FDG PET/CT at baseline and end-of-treatment, analyze the changes in these parameters through treatment, and assess their prognostic values. Materials and Methods: The records of 103 patients with DLBCL (median 54 years [range, 21-76]; male:female, 50:53) were retrospectively reviewed. Skeletal muscle area at the third lumbar vertebral (L3) level was measured, and skeletal muscle index (SMI) was calculated to determine sarcopenia, defined as SMI < 44.77 cm2/m2 and < 32.50 cm2/m2 for male and female, respectively. Glucometabolic parameters of the psoas major muscle, including maximum standardized uptake value (SUVmax) and mean standardized uptake value (SUVmean), were measured at L3 as well. Their changes across treatment were also calculated as ΔSMI, ΔSUVmax, and ΔSUVmean; Δbody mass index was also calculated. Associations between SMI and the metabolic parameters were analyzed, and their associations with progression-free survival (PFS) and overall survival (OS) were identified. Results: The incidence of sarcopenia was 29.1% and 36.9% before and after treatment, respectively. SMI (P = 0.004) was lower, and sarcopenia was more frequent (P = 0.011) at end-of-treatment than at baseline. The SUVmax and SUVmean of muscle were lower (P < 0.001) in sarcopenia than in non-sarcopenia at both baseline and end-of-treatment. ΔSMI was positively correlated with ΔSUVmax of muscle (P = 0.022). Multivariable Cox regression analysis showed that sarcopenia at end-of-treatment was independently negatively associated with PFS (adjusted hazard ratio [95% confidence interval], 2.469 [1.022-5.965]), while sarcopenia at baseline was independently negatively associated with OS (5.051 [1.453-17.562]). Conclusion: Sarcopenic patients had lower muscle glucometabolism, and the muscular and metabolic changes across treatment were positively correlated. Sarcopenia at baseline and end-of-treatment was negatively associated with the prognosis of DLBCL.

Effects of the Modified Fasting Therapy Using Gamrosu and Herbal Medicine on Changes of Body Compositions in Women: Case Series (한약을 결합한 감로수 절식요법이 여성의 체성분 변화에 미치는 영향: 증례보고)

  • Baek, Seon-Eun;Park, Eun-Ji;Kim, Hae-Won;Yoo, Jeong-Eun
    • Journal of Korean Medicine for Obesity Research
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    • v.18 no.2
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    • pp.152-158
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    • 2018
  • The purpose of this study was to investigate the effects of modified fasting therapy using Gamrosu and herbal medicine on the changes of body compositions in women. We analyzed the medical records of 11 patients, who carried out modified fasting therapy at Dunsan Korean Medicine Hospital of Daejeon University. Body compositions (body weight, body mass index, body fat mass, skeletal muscle mass, basal metabolic rate, extracellular water ratio, abdominal circumference, thickness of abdominal subcutaneous fat, visceral fat area) were reviewed before and after modified fasting therapy. The body composition values (body weight, body mass index, body fat mass, skeletal muscle mass, basal metabolic rate, extracellular water ratio, abdominal circumference, thickness of abdominal subcutaneous fat, visceral fat area) decreased after modified fasting therapy. Results from this investigation showed that modified fasting therapy using Gamrosu and herbal medicine has positive effects on changes of body compositions.

A Study on the Validation of Somatotype Drawing as a Instrument of Measuring Obesity Level by Body Component Analysis (생체전기임피던스법을 이용한 체성분 분석에 의한 신체외형도(Somatotype Drawing)의 타당성 연구 - 비만평가도구로서의 타당도 평가 -)

  • Lee Seoung Eun;Jung Young Mi;Chung Kil Soo
    • Journal of Korean Public Health Nursing
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    • v.18 no.2
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    • pp.299-311
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    • 2004
  • Purpose: Somatotype drawing developed by Sorensen et al.(1983) has been evaluated as a simple instrument of obesity level without real somatic measuring as height and weight. This study was designed to validate somatotype drawings for obesity assessment by bioelectrical impedance body component analysis. Method: At first questionnaire of somatotype drawing was done. Subjects were measured body component by bioelectrical impedance analysis as weight, BMI(body mass index), WHR(waist-hip ratio), body water, protein mass, mineral mass, body fat mass, skeletal muscle mass, soft lean mass, fat free mass and percent body fat. We evaluated correlations between these data and somatotype drawings and tried to grouping of somatotype drawings with the means of major body component value. Result: The data were collected from 205 college women whose height and weight were $161.2\pm4.8,\;55\pm8.3$. Spearman's correlation coefficients of somatotype drawing were 0.74 with BMI, 0.68 with weight 0.69 with body fat mass, 0.65 with WHR. 0.64 with percent body fat after adiusted age. The grade of somatotype drawings were grouped as 1-2, 3-4, 5-6. 7-9 by BMI, body fat mass, weight, 1, 2-4, 5-6, 7-9 by WHR and 1-2, 3-4, 5-9 by percent body fat(ANOVA and Duncan's method). Conclusion: So quick instrument using somatotype drawings were useful tools for evaluation of obesity level and is applicable to screen degree of body fat in self-administered questionnaire survey.

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The Relationship between Bone Mineral Density and Body Composition, Life Styles of Female College Students (여대생의 골밀도와 신체조성 및 생활습관과의 관계 연구)

  • Lee, Jong-Hyun;Lee, Bo-Kyung;Kim, Young-Soon
    • The Korean Journal of Food And Nutrition
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    • v.24 no.4
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    • pp.786-796
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    • 2011
  • The purpose of this study was to investigate the relationship between bone mineral density(BMD), body composition and life styles of female college students. The subjects were 334 students with a mean age of 21.0 years. BMDs of forearm and calcaneus were measured by dual energy X-ray absorptiometry, and body composition was measured by bioelectrical impedence analysis. The means for weight, height, and body mass index(BMI) of the subjects were 55.7 kg, 161.0 cm, 21.5 kg/$m^2$, respectively. Grouping by the BMI, 13.2% of the subjects were classified as overweight, and 11.1% of the subjects as obese group. BMD in the forearm and calcaneus were 0.390 g/$cm^2$, 0.514 g/$cm^2$. In the forearm, 58.1% and 9.6% of the subjects were classified as osteopenia and osteoporosis, respectively, and in the calcaneus, 12.0% and 0.3% of the subjects were classified as osteopenia and osteoporosis, respectively. Body weight, skeletal muscle mass, lean body mass, fat mass and BMI were positively correlated with BMDs in the forearm and calcaneus($r$=0.180~0.495, $p$ <0.01~0.001), and height, % body fat and waist-hip ratio(WHR) were positively correlated with BMDs in the calcaneus($r$=0.213~0.239, $p$ <0.001), but not in the forearm. The factors such as beginning age of cigarette smoking and alcohol drinking and exercise had significant influence on BMD($p$ <0.05; p<0.001), whereas sleeping hours, activity level, frequency of exercise, meal times, frequency of snack and fried food intake, breakfast skipping and amount of meal had not significant influence on BMD. Therefore, the acquisition of balanced body composition is necessary through the increase of fat free mass and muscle mass, not through the increase of fat mass among female college students.

Larger Remaining Stomach Volume Is Associated With Better Nutrition and Muscle Preservation in Patients With Gastric Cancer Receiving Distal Gastrectomy With Gastroduodenostomy

  • Kim, Amy;Lee, Jung-Bok;Ko, Yousun;Park, Taeyong;Jo, Hyeonjong;Jang, Jin Kyoo;Lee, Kyoungsuk;Kim, Kyung Won;Lee, In-Seob
    • Journal of Gastric Cancer
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    • v.22 no.2
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    • pp.145-155
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    • 2022
  • Purpose: Weight loss and deterioration in body composition are observed in patients with gastric cancer (GC) following gastrectomy. This study aimed to investigate the impact of residual stomach volume (RSV) on the nutritional status and body composition of patients with GC treated with distal gastrectomy. Materials and Methods: In total, 227 patients who underwent minimally invasive distal gastrectomy with Billroth 1 anastomosis for stage I GC between February 2015 and May 2018 were enrolled. Clinicodemographic and laboratory data were collected from the GC registry. The RSV, abdominal muscle area, and subcutaneous/visceral fat areas were measured using computed tomography data. Results: A larger RSV was associated with a lower decrease in the nutritional risk index (P=0.004) and hemoglobin level (P=0.003) during the first 3 months after surgery, and better recovery at 12 months. A larger RSV demonstrated an advantage in the preservation of abdominal muscle area (P=0.02) and visceral fat (P=0.04) after surgery, as well as less reduction in weight (P=0.02) and body mass index (P=0.03). Conclusions: Larger RSV was associated with improved nutritional status and better preservation of muscle and fat after distal gastrectomy.

Diet and Metabolic Disease Risk Related to Sarcopenia in Pre- and Postmenopausal Adult Women: Based on the Korea National Health and Nutrition Examination Survey (2009-2011) (폐경 전·후 성인 여성에서 근감소증과 관련된 식생활 요인 및 대사성 질환 위험도: 국민건강영양조사(2009-2011) 자료를 활용하여)

  • Kim, Mi Hyun
    • Journal of the Korean Society of Food Culture
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    • v.36 no.4
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    • pp.401-411
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    • 2021
  • Diet is important for muscle health and offers a protective effects against the loss of skeletal muscle mass and physical functions with advancing age. We analyzed the relationship between diet, metabolic disease risk, and sarcopenia in Korean female adults using the 2009-2011 Korea National Health and Nutrition Examination Survey (KNHANES). A total of 2038 adult women aged 50-64 years were classified into four groups based on the diagnosis of menopause and sarcopenia. The groups were the non-menopause and non-sarcopenia group (NMNS, n=249), the non-menopause and sarcopenia group (NMS, n=14), the menopause and non-sarcopenia group (MNS, n=1,653), and the menopause and sarcopenia group (MS, n=122). The socio-demographics, anthropometrics, blood profile, and dietary data of the subjects were collected. Those who were in both the sarcopenia groups were more obese (p<0.001), had greater waist circumferences (p<0.001), higher body mass index (p<0.001), and higher obesity rates (p<0.001) after adjustment for covariants. Both the sarcopenia groups also had higher plasma levels of total cholesterol (p<0.001), HbA1c (p=0.001), and vitamin D (p=0.020) than both the non-sarcopenia groups. Both the sarcopenia groups demonstrated a decreased intake of calcium (p=0.05), potassium (p=0.008), and niacin (p=0.008) than both the non-sarcopenia ones. Among the four groups, the NMS group showed the highest levels of total cholesterol, obesity, and lowest intake of micronutrients such as calcium, niacin, and potassium. Thus, muscle mass maintenance through weight control and adequate nutrient intake appears to demonstrate a potential association with preventing sarcopenia in Korean middle-aged women.

Changes in Blood Parameters and Blood Flow Subsequent to a Short-Term Raw Juice Diet (단기간 생즙섭취에 따른 혈액지표 및 혈류변화)

  • Kim, Sun-Hee;Yim, Jong-Eun;Yun, Mi-Eun
    • Journal of the Korean Dietetic Association
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    • v.26 no.1
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    • pp.14-29
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    • 2020
  • Dietary nitrate supplementation from green leafy vegetables and beetroot is involved in the 'nitrate-nitrite-nitric oxide (NO) pathway' and is reported to have important vascular impacts. This study evaluated the blood parameters and blood flow change subsequent to a raw juice diet program. The 28 subjects who voluntarily participated in the raw juice diet program at Sahmyook University were instructed to drink the juice composed of fruits and vegetables instead of partaking the usual meal, at a scheduled time daily. The study was approved by the research ethics council of the Sahmyook University (SYUIRB 2014-043). Evaluation of the participants after the required duration revealed decreased levels of soft lean mass (P<0.05), skeletal muscle mass (P<0.001), body fat mass (P<0.001), body mass index (P<0.001) and circulating levels of total cholesterol (P<0.001), triglycerides (P<0.05), HDL-cholesterol (P<0.01), LDL-cholesterol (P<0.01), and blood urea nitrogen (P<0.001). Conversely, circulating levels of creatinine (P<0.001), hemoglobin (P<0.001), and hematocrit (P<0.01) were increased after the intervention. The blood flow levels were also increased after the program (P<0.001). Our results indicate that a short-term raw juice diet contributes to the improvement of vascular blood flow and blood lipid parameters, and decreases the lean muscle mass related to dehydration.

Effects of Rhythm Exercise Training on Body Composition and Arterial Compliance in Elderly Females (리듬운동이 고령여성의 신체조성과 혈관탄성에 미치는 영향)

  • Kim, Daeyeol
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.5
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    • pp.243-250
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    • 2016
  • The body composition and arterial compliance with advanced age increase the risks of cardiovascular diseases, but the elderly can perform rhythm exercise easily, which may positively influence their body composition and arterial compliance. Therefore, this study examined the effects of rhythm exercise training on the body composition and arterial compliance in elderly females. The subjects (n=20) were assigned randomly to either an exercise group (n=10, EX) or non-exercise control group (n=10, CON). The rhythm exercise training for 12 weeks consisted of 3 sessions per week with 60 minutes per session. In addition, the intensity was set to 11-14 of the Borg scale (6-20). The body composition and arterial compliance (pulse wave velocity (PWV)) were measured before and after training. The skeletal muscle mass in the EX was increased significantly (p=0.04) and the right (p=0.002) and left side (p=0.02) of the PWV in the EX were decreased significantly, but the skeletal muscle and both sides of the PWV in the CON were not changed. Elderly females could easily perform rhythm exercise training, which resulted in improvements of the skeletal muscle mass and arterial compliance. Therefore, rhythm exercise training may prevent or delay sarcopenia and reduce the risk of cardiovascular diseases.

Effects of Community Based Participatory Obesity Intervention Program in Middle-Aged Women (중년 여성 대상의 지역사회 참여형 비만 중재 프로그램의 효과)

  • Kim, Hyun
    • Journal of Korean Public Health Nursing
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    • v.29 no.1
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    • pp.79-89
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    • 2015
  • Purpose: The aim of the study was to determine the effects of a community based participatory program in obese middle-aged women. Methods: One-group pretest-posttest design was used. The subjects were 35 middle-aged women. Data were collected at public health centers in Chungcheongnam-Do from March to May, 2013. To evaluate the effect of the program, physiological indexes(body mass index, skeletal muscle mass, body fat mass, visceral fat area) and health behavior indexes(dietary practice guidelines score, moderate physical activity, drinking frequency) were measured. Analysis was performed using a Wilcoxon Signed Rank Test. Results: After the program, physiological indexes (BMI, BFM, SMM, VFA) and health behavior indexes (dietary guidelines scores, frequency of physical activity, drinking frequency) were significantly improved. Conclusion: The community based participatory obesity program by public health centers is considered to be effective. Therefore, greater effort is needed for better participatory program development of several health promoting fields, and more research is needed in order to examine a continuous effect.