• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5407-5409
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• 2014

Background: In National Cancer Registry Programme (NCRP) reports, various rates are routinely provided for 50 cancer sites of males and 54 cancer sites of females. Very often, depending on our interest, we wish to see these rates for group of cancers like head and neck cancers, oral cancers, and reproductive cancers. In such a situation, the desired rates are calculated independently from the actual data and reported. The question is can we derive the rates for groups of cancers from the published reports when the data is provided only for the individual sites? Objective: In the present paper, an attempt is made to explore the mathematical properties of various rates to derive them directly for the group of cancer sites from the published data when the rates are provided only for the individual sites. Source of data: The cancer incidence data collected by two urban Population Based Cancer Registries (PBCRs), under the network of NCRP for the period of 2006-08 was considered for the study purposes. The Registries included were: Bangalore and Bhopal. Results: In the present communication, we have shown that the crude rate (CR), age specific rates and age-adjuste rates (AAR) all possess additive properties. This means, given the above rates for individual sites, the above rates can be calculated for groups of sites by simply adding them. In terms of formula it can be stated that CR(Site1+Site2+++ SiteN) = CR(Site1)+CR(Site2) +++ CR(SiteN). This formula holds good for age specific rates as well as for AAR. This property facilitates the calculation of various rates for defined groups of cancers by simply adding the above rates for individual sites from which they are made up.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5681-5684
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• 2014

Objective: Prevalence is a statistic of primary interest in public health. In the absence of good follow-up facilities, it is often difficult to assess the complete prevalence of cancer for a given registry area. An attempt is made to arrive at the complete prevalence including limited duration prevalence with respect of selected sites of cancer for India by fitting appropriate models to 1, 3 and 5 year cancer survival data available for selected registries of India. Methodology: Cancer survival data, available for the registries of Bhopal, Chennai, Karunagappally, and Mumbai was pooled to generate survival for the selected cancer sites. With the available data on survival for 1, 3 and 5 years, a model was fitted and the survival curve was extended beyond 5 years (up to 30 years) for each of the selected sites. This helped in generation of survival proportions by single year and thereby survival of cancer cases. With the help of estimated survived cases available year wise and the incidence, the prevalence figures were arrived for selected cancer sites and for selected periods. In our previous paper, we have dealt with the cancer sites of breast, cervix, ovary, lung, stomach and mouth (Takiar and Jayant, 2013). Results: The prevalence to incidence ratio (PI ratio) was calculated for 30 years duration for all the selected cancer sites using the model approach showing that from the knowledge of incidence and P/I ratio, the prevalence can be calculated. The validity of the approach was shown in our previous paper (Takiar and Jayant, 2013). The P/I ratios for the cancer sites of lip, tongue, oral cavity, hypopharynx, oesophagus, larynx, nhl, colon, prostate, lymphoid leukemia, myeloid leukemia were observed to be 10.26, 4.15, 5.89, 2.81, 1.87, 5.43, 5.48, 5.24, 4.61, 3.42 and 2.65, respectively. Conclusion: Cancer prevalence can be readily estimated with use of survival and incidence data.

• 한국물환경학회지
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• 제33권1호
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• pp.40-50
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• 2017

We were interested in the long-term temporal and spatial variability trends of water quality. Trend tests such as the Seasonal and Regional Kendall tests and LOWESS (LOcally WEighted Scatter plot Smoother) have been recommended as outstanding tools for trend detection. In this study, we conducted four types of nonparametric trend tests (Seasonal and Regional Kendall tests, LOWESS, and flow-adjusted Seasonal Kendall). We aimed to identify water quality trends using the monthly data for five variables (BOD, COD, TN, TP, and flow) collected from 24 sites in the Nakdong River from August 2004 to December 2013. According to the Regional Kendall test, BOD, COD, and TN increased but TP decreased trend. The Seasonal Kendall test showed that BOD, TN, and TP remained constant at 62.5-83.3% of the sites. COD remained constant at 58.3% of the sites. LOWESS showed that TP gradually increased between 2007 and 2008, then decreased slowly at the Gumi, Geumhogang6, Daeam-1 and Milyanggang3 sites. BOD increased slightly between 2008 and 2009, and then decreased slowly at the Namgang4-1 site. Lastly, a flow-adjusted Seasonal Kendall test was conducted. There were different results between Seasonal Kendall and flow-adjusted Seasonal Kendall tests at 11 of the 24 sites. According to the results from six of the eleven sites, BOD increased at one site, showed no trends at three sited, and decreased at two sites. Each of COD, TN increased at two, one site. but TP decreased at two sites.

• 디지털융복합연구
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• 제5권2호
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• pp.99-108
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• 2007

As the transaction using mail order sales mediating sites such as Auction rapidly increase, consumer damages are also increasing. Therefore, in this study, the methods to remedy consumer damages occurring from transactions through mail order sales mediating sites such as the Payment Deposit System, the systems to resolve disputes without any litigation and the systems in relation to the Consumer Basic Act have been examined and measures to improve the systems have been groped. For the transactions using mail order sales intermediating sites, it is necessary to impose more responsibility on mail order sales mediators although the responsibility may not be required to be at the level of mail order sellers such as internet shopping malls. Therefore, institutional supports are necessary to effectively protect consumers in the transactions using mail order sales mediating sites and to induce damaged consumers to actively file claims for compensations. In relation to this, the Collective Dispute Mediation System and the Consumer Group Litigation System under the Consumer Basic Act may become good examples. The consumers who have been subject to the same or similar damages in the transactions using mail order sales mediating sites should also be allowed to participate in the Collective Dispute Mediation under the Consumer Basic Act or actively utilize the Consumer Group Litigation System. Also, it is desirable to reflect these systems on 'the Act on Consumer Protection in E-Commerce etc' so that these systems can also be directly applied to the transactions using mail order sales mediating sites.

• Safety and Health at Work
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• 제3권4호
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• pp.278-286
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• 2012

Objectives: Authors investigated the pattern of the rate of occupational injuries and illnesses (ROII) at the level of enterprises in order to build a network for exchange of experience and knowledge, which would contribute to workers' safety and health through safety climate of workplace. Methods: Occupational accidents were analyzed at the manufacturing work site unit. A two step clustering process for the past patterns regarding the ROII from 2001 to 2009 was investigated. The ROII patterns were categorized based on regression analysis and the patterns were further divided according to the subtle changes with Mahalanobis distance and Ward's linkage. Results: The first clustering of ROII through regression analysis showed 5 different functions; 29 work sites of the linear function, 50 sites of the quadratic function, 95 sites of the logarithm function, 62 sites of the exponential function, and 54 sites of the sine function. Fourteen clusters were created in the second clustering. There were 3 clusters in each function categorized in the first clustering except for sine function. Each cluster consisted of the work sites with similar ROII patterns, which had unique characteristics. Conclusion: The five different patterns of ROII suggest that tailored management activities should be applied to every work site. Based on these differences, the authors selected exemplary work sites and built a network to help the work sites to share information on safety climate and accident prevention measures. The causes of different patterns of ROII, building network and evaluation of this management model should be evaluated as future researches.

• 한국임상수의학회지
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• 제22권3호
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• pp.181-185
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• 2005

개의 아토피성 피부염의 피부증상이 호발하는 8부위에서 비만세포의 분포를 조사 비교하였다. 피부증상을 보이지 않는 10두의 개의 8부위의 피부조직을 채취하여 비만세포에서 특이적인 acidfied toluidine blue 염색을 하여 현미 경하에서 계수비교하였다. 비만세포수는 표재진피에서 각각의 부위간에 유의한 변화가 관찰되었으며 (p<0.0001) 표재진피가 심재진피에 비해 유의하게 높았다 (p<0.05). 호발 부위중 비만세포가 가장 높은 부위는 내측이개와 지간으로 각각 $74.88{\pm}17.93\;per\;mm^2$, $28.33{\pm}6.24\;per\;mm^2$이었다. 이 부위는 다른 부위에 비해 비만세포가 $280{\%}$ 높게 분포하였다. 따라서 개의 아토피성 피부염의 호발증상인 귀와 발의 소양증의 발생은 비만세포의 수가 다른 부위에 비해 높은 것이 하나의 요인으로 사료된다. 그러나 비만세포의 수가 낮게 나타난 다른 호발부위에 대해서는 다른 요인이 관계하는 것으로 사료되며 이에 관한 연구가 필요하다.

• 한국산림과학회지
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• 제104권2호
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• pp.309-318
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• 2015

본 논문은 수목장지 공급이 님비현상으로 정체되고 있는 상황을 해결할 수 있는 방안을 제언하기 위한 연구이다. 이를 위해 님비현상의 해결에 성공한 국내외 수목장지 조성사례에 대해 현지 방문 조사와 인터뷰를 진행하고, 사례지에서 수목장지가 장사시설의 이미지로 받아들여짐에 따라 발생하는 지역주민의 피해를 효과적으로 해결할 수 있었던 요인을 분석하였다. 조사결과, 국내 사례에서는 경제적 보상 제공, 공동묘지 내 조성, 사찰림을 활용한 조성을 통해 님비현상을 해결한 유형이 도출되었다. 해외 사례에서는 수목장지가 장사시설이 아닌 명소의 이미지를 갖도록 한 유형과 경제적 유인을 통해 지역주민의 자발적인 조성 참여를 유도한 유형을 확인하였다. 이러한 연구결과를 바탕으로 공동묘지의 재개발, 수목장지의 명소화, 공모방식을 통한 지역주민의 PIMFY 유도를 수목장지에 대한 님비현상의 해결방안으로 제언하였다.

• 디지털콘텐츠학회 논문지
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• 제18권5호
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• pp.949-956
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• 2017

오늘날 인터넷 신문들은 대중적인 디지털 콘텐츠로 자리잡고 있다. 인터넷 신문의 시각적 인터페이스는 대동소이하나 그 골조를 이루는 HTML의 수준 및 규격은 천차만별이다. HTML의 가장 기본적인 목적이 다른 컴퓨터도 이해할 수 있도록 문서를 의미론적으로 기술하는 것이기에 HTML5에서 문서의 시맨틱스(semantics)는 더욱 강조되고 있다. 본 연구에서는 글로벌 인터넷 신문 8개의 HTML을 대조군으로 삼아 한국의 110개 인터넷 신문을 분석하여 실질적으로 문서에 사용된 HTML 규격을 점검하고 그 시맨틱스의 수준을 진단하였다. 분석 결과 조사대상인 110개 한국의 인터넷신문 중 68%가 HTML4 규격에 해당하는 것으로 나타났으며, 110개 중 9%에 해당하는 10개의 웹사이트만이 대조군으로 조사한 글로벌 인터넷신문과 동일한 수준의 HTML5 규격으로 작성되었으며 적극적인 시맨틱스를 적용하고 있는 것으로 나타났다. 번역기술이 인공지능으로 인해 한층 개선되고 있는 이 시점에 한국 인터넷신문의 디지털 콘텐츠들이 세계와 소통하기 위해서는 더욱 더 적극적인 시맨틱스를 적용한 HTML 문서 작성 플랫폼으로의 규격 전환이 필요하다.

• Bulletin of the Korean Chemical Society
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• 제22권5호
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• pp.514-518
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• 2001

We have explored the importance of two ATP binding domains of Hsp104 protein in protection of yeast cells from cadmium exposure. In the previous study we have discovered that the presence of two ATP binding sites was essential in providing heat sh ock protection as well as rescuing cells from oxidative stress. In this paper we first report wild type cell with functional hsp104 gene is more resistant to cadmium stress than hsp104-deleted mutant cell, judging from decrease in survival rates as a result of cadmium exposure. In order to demonstrate functional role of two ATP binding sites in cadmium defense, we have transformed both wild type (SP1) and hyperactivated ras mutant (IR2.5) strains with several plasmids differing in the presence of ATP binding sites. When an extra copy of functional hsp104 gene with both ATP binding sites was overexpressed with GPD-promoter, cells showed increased survival rate against cadmium stress than mutants with ATP binding sites changed. The degree of protection in the presence of two ATP binding sites was similarly observed in ira2-deleted hyperactivated ras mutant, which was more sensitive to oxidative stress than wild type cell. We have concluded that the greater sensitivity to cadmium stress in the absence of two ATP binding sites is attributed to the higher concentration of reactive oxygen species (ROS) produced by cadmium exposure based on the fluorescence tests. These findings, taken all together, imply that the mechanism by which cadmium put forth toxic effects may be closely associated with the oxidative stress, which is regulated independently of the Ras-cAMP pathway. Our study provides a better understanding of cadmium defense itself and cross-talks between oxidative stress and metal stress, which can be applied to control human diseases due to similar toxic environments.

• 한국물환경학회지
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• 제37권3호
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• pp.190-203
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• 2021

Water quality, benthic macroinvertebrate communities, and other factors were investigated to explore the effects of the effluent discharge from a sewage treatment plant into Jwagwang stream in Busan in 2019. During the study period, the flow rate of this stream was in the range of 10,400 m³/day to 52,200 m³/day except for the discharge of about 24,000 m³/day of the effluent. After discharge, the flow velocity increased by about 65% and the water depth increased by about 40%. At sites downstream of the discharge point, BOD, COD, TOC, T-N, T-P, and other water quality values were worse than those of the upstream sites. The periphytic algal chlorophyll-a concentrations in the natural substrata were higher than those of the upstream sites, especially in May and August. However, at sites downstream of the discharge point, the individual numbers of Annelida were decreased and individual numbers of the insecta of arthropoda were increased. Also, species numbers and the diversity and dominance indexes were improved in the sites downstream of the discharge point. The functional feeding groups (FFGs) of collector-filterers were increased and the habitat orientation groups (HOGs) of sprawlers, burrowers, and clingers were especially increased at the sites with additional reclaimed wastewater effluent flow. Regardless of the effluent discharge, BMI, an indicator of ecological stream health using benthic macroinvertebrate species, did not show large gaps between the study points. Although the water quality of the sites downstream of the discharge point was much worse than those upstream, their ecosystem soundness was better than those of the upstream sites from an ecological perspective.