• Proceedings of the Korean Society of Toxicology Conference
• /
• 2001.10a
• /
• pp.107-107
• /
• 2001

In the present study, the protective effect of Scutellaria baicalensis against DNA damage in HL-60 cells exposed to $^{60}$ Co ${\gamma}$-rays was evaluated using micronuclei formation and alkaline single cell gel electrophoresis (SCGE, comet assay). The frequency of micronuclei was decreased in groups treated with water extract (P＜0.01), polysaccaride fraction (P＜0.01) and methanol fraction (P＜0.01) before/after exposure to 200 cGy of ${\gamma}$-rays.(omitted)

• Genomics & Informatics
• /
• v.4 no.2
• /
• pp.57-64
• /
• 2006

We identified differentially expressed genes in RAW264.7 cells in response to single and double ligand treatments (LPS, $IFN{\gamma}$, 2MA, LPS plus $IFN{\gamma}$, and LPS plus 2MA). The majority of the regulated transcripts responded additively to dual ligand treatment. However, a significant fraction responded in a non-additive fashion. Several cytokines showing non-additive transcriptional responses to dual ligand treatment also showed non-additive protein production/secretion responses in separately performed experiments. Many of the genes with non-additive responses to LPS plus 2MA showed enhanced responses and encoded pro-inflammatory proteins. LPS plus $IFN{\gamma}$ appeared to induce both non-additive enhancement and non-additive attenuation of gene expression. The affected genes were associated with a variety of biological functions. These experiments reveal both dependent and independent regulatory pathways and point out the specific nature of the regulatory interactions.

• Korean Journal of Microbiology
• /
• v.29 no.5
• /
• pp.278-283
• /
• 1991

Two amino acid residues ($Ala^{494}$ and $Ser^{495}$ of E. coli .gamma.-glutamylcysteine synthetase have been investigated whether they are the site of feedback inhibition by site specific mutagenesis. Single substitution of $serine^{495}$ (S495F), and double substitutions of alanine$^{494}$ and $serine^{495}$ (A494G-S495F) resulted in the inactivation of the .gamma.-glutamylcysteine synthetase activity. Substitution of $alanine^{494}$ with $glycine^{494}$ resulted in a higher level of feedback inhibition. These results suggest that $serine^{495}$ in .gamma.-glutamylcysteine synthetase is required for its catalytic acitvity and $alanine^{494}$ is presumably related to the feeback inhibition site.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• v.8 no.4
• /
• pp.28-32
• /
• 2009

This paper compares two speech estimators under a generalized Gamma distribution for DFT-based single-microphone speech enhancement methods. For the speech enhancement, the noise estimation based on recursive averaging spectral values by spectral minimum noise is applied to two speech estimators based on the generalized Gamma distribution using $\kappa$=1 or $\kappa$=2. The performance of two speech enhancement algorithms is measured by recognition accuracy of automatic speech recognition(ASR) in car noisy environment.

• Journal of Korea Society of Digital Industry and Information Management
• /
• v.15 no.1
• /
• pp.99-107
• /
• 2019

Retinex-based image enhancement is a technique that utilizes the property that the human visual characteristics are sensitive to the difference from the surrounding pixel value rather than the pixel value itself. These Retinex-based algorithms show different characteristics of the improved image depending on the applied color space or gamma correction. In this paper, we set eight different experimental conditions according to the application of color space and gamma correction, and analyze the objective and subjective performance of each Retinex based image enhancement algorithm and apply it to the implementation of Retinex based algorithm. In the case of gamma correction, quantitative low entropy images and low contrast images are obtained. The application of Retinex technique in HSI color space rather than RGB color space is found to be high in overall subjective image quality as well as maintaining color.

• Journal of Korean Neurosurgical Society
• /
• v.44 no.2
• /
• pp.67-71
• /
• 2008

Objective : Radiosurgery may be contraindicated for lesions adjacent to the optic pathways because of the substantial risk of visual complication. Multisession radiosurgery has been tried as a compromise between single session radiosurgery and fractionated radiotherapy. The purpose of this study is to evaluate the outcomes of multisession gamma knife radiosurgery (GKRS) in 22 patients with perioptic lesions of benign pathology. Methods : In all 22 cases, the lesions were within 1 mm of the optic apparatus and were therefore not considered suitable for single session radiosurgery. Radiation was delivered in 3 to 4 fractions with a median cumulated marginal dose of 20 Gy (range, 15-20 Gy). Results : During a mean follow-up of 29 months (range, 14-44 months), tumor control was achieved in 21 patients. Visual function improved in 7 patients, remained unchanged in 14 patients, and deteriorated in 1 patient with tumor progression. No other complication was observed. Conclusion : This preliminary result supports the idea that multisession GKRS may be an effective and safe alternative for treatment in perioptic lesions that are unsuitable for single session radiosurgery.

• Korean Journal of Materials Research
• /
• v.27 no.7
• /
• pp.369-373
• /
• 2017

Unidirectionally solidified TiAl alloys were prepared by optically-heated floating zone method at growth rates of 10 to 70 mm/h in flowing argon. The microstructures and tensile properties of these crystal bars were found to depend strongly on the growth rate and alloy composition. TiAl alloys with composition of 47 and 50 at.%Al grown under the condition of 10 mm/h showed $Ti_3Al({\alpha}_2)/TiAl({\gamma})$ layer structures similar to single crystals. As the growth rate increased, the alloys with 47 and 50 at.%Al compositions showed columnar-grain structures. However, the alloys fabricated under the condition of 10 mm/h had a layered structure, but the alloy with increased growth rate consisted of ${\gamma}$ single phase grains. The alloy with a 53 at.%Al composition showed a ${\gamma}$ single phase regardless of the growth rate. Room-temperature tensile tests of these alloys revealed that the columnar-grained material consisting of the layered structure showed a tensile ductility of larger than 4 % and relatively high strength. The high strength is caused by stress concentration at the grain boundaries; this enhances the secondary slip or deformation twinning across the layered structure in the vicinity of the grain boundaries, resulting in the appreciable ductility.

• Fibers and Polymers
• /
• v.5 no.2
• /
• pp.156-159
• /
• 2004

Novoloid fibers have high chemical, flame and thermal resistance; however they have low tensile properties. Effects of gamma irradiation on the tensile properties of novoloid fibers have been investigated. Loop and knot resistance have also been examined. Maximum tenacity of the single fiber increased with an increase of the radiation dose applied. According to the loop and knot tenacity results it is found that brittleness has been also affected by the amount of radiation dose.

• Nuclear Engineering and Technology
• /
• v.35 no.4
• /
• pp.347-355
• /
• 2003

The \gamma-ray spectrometer of the PGAA (Prompt Gamma Activation Analysis) facility constructed at HANARO of the Korea Atomic Energy Research Institute was upgraded to the multi-mode spectrometer including the single mode, the Compton suppression mode and the pair mode. The performance of the spectrometer was tested and summarized. The background count rate and the uncertainty of the detection efficiency were reduced greatly in comparison with those before the new installation.

• Journal of Korean Society for Quality Management
• /
• v.15 no.2
• /
• pp.55-60
• /
• 1987

A rectifying inspection plan which assumes a gamma - prior distribution on the lot percent defective is considered. This sampling inspection plan is developed for finite lot sizes with matching OC curves and generated from an initial plan selected from KS A 3102 single sampling by attributes. Comparisons are made with each plan by three examples.