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The evaluation of risk for aspiration using lipid-laden macrophage index in infants with bronchiolitis (지질함유 대식세포 지표(lipid-laden macrophage index)를 이용한 세기관지염 환아에서 흡인의 위험성 평가)

  • Koh, Ji Yeon;Kang, Hee;Chung, Ju Young;Han, Tae Hee;Kim, Chang Keun
    • Clinical and Experimental Pediatrics
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    • v.49 no.7
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    • pp.763-768
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    • 2006
  • Purpose : We investigated the risk of aspiration using the lipid-laden macrophage index(LLMI) from laryngeal lavages in infants with bronchiolitis. Methods : Laryngeal lavages from 22 infants with acute bronchiolitis caused by respiratory syncytial virus(RSV) were evaluated during the acute stage. Repeat studies were performed at 3 to 4 weeks after the initial study(remission stage). Lavage cell counts and differentials were determined. The amount of lipid per single macrophage was evaluated and the LLMI was determined by evaluating 100 cells. Comparisons between acute stage and remission stage were made. Twenty-four hour pH monitoring(pHm) was performed in 12 patients. Results : The total cell number was significantly higher in the acute stage compared with the remission stage(P<0.05). The LLMIs in the acute stage were significantly higher than those in the remission stage(P<0.05). The neutrophils percentage of laryngeal lavage correlated with the LLMI(r=0.69, P<0.001). Four children had positive pHm recordings(pH-positive infants) and eight had negative pHm recordings(pH-negative infants). The pH-positive infants had higher LLMI and higher neutrophils percentage than those of the pH-negative infants(P<0.05). Conclusion : These findings suggest that there is a transient increased risk of aspiration during bronchiolitis. The LLMI from laryngeal lavage may be a useful marker for pulmonary aspiration in infants with bronchiolitis.

Combination Effects of Potassium Sorbate and Sodium Benzoate with sodium Chloride on the Growth Inhibition of Escherichia coli and Salmonella typhimurium (Escherichia coli 와 Salmonella typhimurium 의 생육억제에 미치는 식염과 Potassium Sorbate, Sodium Benzoate의 병용효과)

  • Cho, Nam-Sook;Yang, Yeo-Young;Choi, Eon-Ho
    • Korean Journal of Food Science and Technology
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    • v.18 no.4
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    • pp.249-254
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    • 1986
  • An experiment was performed to investigate the combined effect of preservatives and the synergistic effect of sodium chloride to them on the inhibition of bacterial growth. Escherichia coli and Salmonella typhimurium were cultured with or without shaking in liquid media (pH 6) of tryptone-glucose-yeast extract or tryptic soy broth which contained 0.1% potassium sorbate and/or 0.03% sodium benzoate, equivalent to half of the maximum permissible levels, respectively. The growth of E. coli was more inhibited with one or both of the two preservatives by shaking culture than by non-shaking culture. For S. typhimurium the single treatment of the preservatives did not show inhibitory effect whereas the combined treatment of them showed bacteriostatic effect in shaking culture and a prolongation of lag phase in non-shaking culture. Addition of 2% sodium chloride to either potassium sorbate or potassium sorbate plus sodium benzoate remarkably increased the growth inhibition of E. coli for non-shaking cultivation but no effect observed for shaking cultivation. S. typhimurium was more sensitive to the addition of sodium chloride than E. coli in both shaking and non-shaking culture to show lower viable cell counts than initial numbers.

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Development of a Spectrum Analysis Software for Multipurpose Gamma-ray Detectors (감마선 검출기를 위한 스펙트럼 분석 소프트웨어 개발)

  • Lee, Jong-Myung;Kim, Young-Kwon;Park, Kil-Soon;Kim, Jung-Min;Lee, Ki-Sung;Joung, Jin-Hun
    • Journal of radiological science and technology
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    • v.33 no.1
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    • pp.51-59
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    • 2010
  • We developed an analysis software that automatically detects incoming isotopes for multi-purpose gamma-ray detectors. The software is divided into three major parts; Network Interface Module (NIM), Spectrum Analysis Module (SAM), and Graphic User Interface Module (GUIM). The main part is SAM that extracts peak information of energy spectrum from the collected data through network and identifies the isotopes by comparing the peaks with pre-calibrated libraries. The proposed peak detection algorithm was utilized to construct libraries of standard isotopes with two peaks and to identify the unknown isotope with the constructed libraries. We tested the software by using GammaPro1410 detector developed by NuCare Medical Systems. The results showed that NIM performed 200K counts per seconds and the most isotopes tested were correctly recognized within 1% error range when only a single unknown isotope was used for detection test. The software is expected to be used for radiation monitoring in various applications such as hospitals, power plants, and research facilities etc.

Preparation and Characteristics of Yogurt from Milk Added with Soy Milk and Brown Rice (두유와 현미를 첨가한 요구르트의 제조 및 특성)

  • Jeoun, Ki-Suk;Kim, Youn-Jung;Park, Shin-In
    • Korean Journal of Food Science and Technology
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    • v.27 no.1
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    • pp.47-55
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    • 1995
  • New type yogurts were prepared by fermenting whole milk containing soy milk and/or brown rice with single or mixed culture of 4 types of lactic acid bacteria(Lactobacillus acidophilus, Lactobacillus bulgaricus, Leuconostoc mesenteroides, Streptococcus thermophilus). The curd yogurts were evaluated by acid production (pH, titratable acidity), number of viable cell, keeping quality and sensory property. Addition of soy milk and brown rice markedly stimulated the acid production and propagation of lactic acid bacteria, and slightly increased the Brix degree. Among the organisms tested, the mixed culture of Leuconostoc mesenteroides and Streptococcus thermophilus produced the highest amount of acid, and that of Leuconostoc mesenteroides and lactobacillus acidophilus showed the highest number of viable cell counts. When curd yogurt added with soy milk and brown rice was kept at $3^{\circ}C$ for 15 days, its keeping quality was relatively good. The sensory evaluation showed that the curd yogurt containing soy milk and brown rice slightly reduced the texture property and overall acceptability comparing with milk yogurt.

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Effect of Electrolyzed Water and Organic Acids on the Growth Inhibition of Listeria monocytogenes on Lettuce (전해수 및 유기산처리에 의한 양상치에 오염된 Listeria monocytogenes의 생육저해)

  • Park Boo-Kil;Oh Min-Hee;Oh Deog-Hwan
    • Food Science and Preservation
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    • v.11 no.4
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    • pp.530-537
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    • 2004
  • This study was conducted to determine the inactivation effect of electrolyzed water and organic acids either alone or in combination on L. monocytogenes or natural microflora on lettuce. Acidic electrolyzed water completely inactivated L. monocytogenes in broth system within 60 sec, but alkalin electrolyzed water caused approximate 1.7 log CFU/g reduction. However, acidic electrolyzed water reduced only 2.5 log CFU/g of L. monocytogenes on lettuce, and similar antimicrobial effect was observed with alkalin electrolyzed water. In the meantime, acidic and alkaline electrolyzed water caused approximately 2 log CFU/g reduction compared to control, whereas both electrolyzed water combined with $1\%$ organic acids ranged from 2.6 to 3.7 log CFU/g reduction. Among the organic acids, both electrolyzed water combined with $1\%$ citric acid showed the strongest synergistic antimicrobial effect to reduce L. monocytogenes on lettuce as well as total counts, yeast and molds. When antimicrobials, alone or in combination were treated into L. monocytogenes inoculated lettuce at $5^{\circ}C\;and\;15^{\circ}C$ for designed periods, the combined alkalin electrolyzed water with $1\%$ citric acid showed the greatest potential to inhibit growth of the bacteria. According to Scanning Electron Microscopy(SEM), the treatment of electrolyzed alkali water in combination with $1\%$ citric acid highly reduced the growth of the L. monocytogenes compared to single treatment and resulted in causing the destruction of cell membrane.

An Enhanced DESYNC Scheme for Simple TDMA Systems in Single-Hop Wireless Ad-Hoc Networks (단일홉 무선 애드혹 네트워크에서 단순 TDMA 시스템을 위한 DESYNC 알고리즘 개선 방안)

  • Hyun, Sanghyun;Lee, Jeyul;Yang, Dongmin
    • KIPS Transactions on Computer and Communication Systems
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    • v.3 no.9
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    • pp.293-300
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    • 2014
  • TDMA(Time Division Multiple Access) is a channel access scheme for shared medium networks. The shared frequency is divided into multiple time slots, some of which are assigned to a user for communication. Techniques for TDMA can be categorized into two classes: synchronous and asynchronous. Synchronization is not suitable for small scale networks because it is complicated and requires additional equipments. In contrast, in DESYNC, a biologically-inspired algorithm, the synchronization can be easily achieved without a global clock or other infrastructure overhead. However, DESYNC spends a great deal of time to complete synchronization and does not guarantee the maximum time to synch completion. In this paper, we propose a lightweight synchronization scheme, C-DESYNC, which counts the number of participating nodes with GP (Global Packet) signal including the information about the starting time of a period. The proposed algorithm is mush simpler than the existing synchronization TDMA techniques in terms of cost-effective method and guarantees the maximum time to synch completion. Our simulation results show that C-DESYNC guarantees the completion of the synchronization process within only 3 periods regardless of the number of nodes.

Aspirin Reduces Acute Lung Injury in Rats Subjected to Severe Hemorrhage (Aspirin이 출혈성 쇼크로 인한 급성 폐손상에 미치는 효과)

  • Shin, Tae Rim;Lee, Dong Uk;Park, Yoon-Yub
    • Tuberculosis and Respiratory Diseases
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    • v.54 no.5
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    • pp.522-531
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    • 2003
  • Background : Hemorrhagic shock and trauma are two of the most common causes of acute lung injury. The activation of cyclooxygenase is one of the important causes of acute lung injury. This study investigated the effect of aspirin, a well-known cyclooxygenase inhibitor, on severe hemorrhage-induced acute lung injury in rats. Methods : The hemorrhagic shock was induced by withdrawing blood; 20ml/kg of B.W., through the femoral artery in 5 min. The mean arterial pressure was recorded through the femoral artery on a polygraph. Results : In the present investigation, the lung tissue myeloperoxidase activity, protein contents and leukocyte counts, in bronchoalveolar lavage fluid, increased significantly 2 and 24 h after the hemorrhage induction. Although the decreased mean arterial pressure spontaneously recovered, acute lung injury occurred after severe hemorrhage. These changes were effectively prevented by a single intravenous injection of aspirin (10 mg/kg of B.W.) 30 min before the hemorrhage. Conclusion : These results suggest that severe hemorrhage-induced acute lung injury is mediated, in part, by the activation of cyclooxygenase. Furthermore, pretreatment of aspirin in acute lung injury-prone patients, or prophylactic treatment of aspirin to the patients with precipitating conditions, could be helpful in the prevention of acute lung injury.

A New High-Efficient Interleaved Converter for Low-Voltage and High-Current Power Systems (저전압 고전류 사양에 적합한 고효율 인터리브 컨버터)

  • Cho, In-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.10
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    • pp.600-608
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    • 2016
  • This paper proposes a new high-efficient interleaved phase-shift full-bridge (PSFB) converter for low-voltage and high-current power systems. The proposed converter is composed of three switch-bridges and two transformers in the primary side and two rectifiers in the secondary side. Each transformer handles half of the total power with an interleaved operation, so that the proposed converter has high system reliability, as much as the conventional interleaved PSFB converter. The soft-switching characteristics of the proposed converter are better than those of the conventional converter due to the modulated primary side configuration. The proposed converter represents a single lagging-leg bridge, which has a poor soft switching condition in its operation, while the conventional converter has two lagging-leg bridges in its operation. Therefore, the number of switches having hard-switching conditions is reduced by half in the proposed converter. In addition, the reduced switch counts in the primary side of the proposed converter helps decrease the complexity of the proposed converter compared to that of the conventional converter. The operational principle and analysis are presented in this paper and the characteristics are verified using a PSIM simulation with 3kW server power specification.

Clinical and Radiological Findings of Coronavirus Disease 2019 Pneumonia: 51 Adult Patients from a Single Center in Daegu, South Korea (Coronavirus Disease 2019 폐렴의 임상적, 영상의학적 소견: 대구의 단일 기관에서 51명의 성인 환자를 대상으로 한 분석)

  • Seung Eun Lee;Young Seon Kim
    • Journal of the Korean Society of Radiology
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    • v.81 no.3
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    • pp.591-603
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    • 2020
  • Purpose The purpose of this study was to describe the clinical features and chest computed tomography (CT) findings of coronavirus disease 2019 (COVID-19) pneumonia. Materials and Methods An Institutional Review Board-approved retrospective review was performed for 51 laboratory-confirmed COVID-19 pneumonia patients. Patients were divided into two groups depending on their clinical status: mild and severe. Clinical characteristics and chest CT findings were compared between the two groups. Results Among the 51 patients (22 men, 29 women; mean age, 56.5 ± 16 years; range, 22-88 years), 37 (72.5%) were in the mild group and 14 (27.5%) were in the severe group. The patients in the severe group (68.7 ± 12.5 years) were older than the patients in the mild group (51.8 ± 14.9 years, p < 0.001). Premorbid conditions and decreased lymphocyte counts were more often observed in the severe group than in the mild group (71% vs. 41%, p = 0.049 and 86% vs. 32%, p = 0.001, respectively). On chest CT, most patients exhibited a mixed ground-glass opacification (GGO) with consolidation (76%) or a GGO (22%) pattern. The majority of lesions were predominantly bilateral in the lower lung with a posterior, peripheral distribution. The patients in the severe group had higher severity scores than those in the mild group. Conclusion Patients with laboratory-confirmed COVID-19 pneumonia have typical chest CT findings that provide important information regarding expected disease severity.

Measurement of Radon Daughters' Radioactivities by Using Single Filtering Method (단일집진법(單一集塵法)에 의(依)한 라돈 붕괴생성물(崩壞生成物)의 농도측정(濃度測定))

  • Chang, Si-Young;Ro, Seung-Gy;Hong, Jong-Sook
    • Journal of Radiation Protection and Research
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    • v.6 no.1
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    • pp.25-30
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    • 1981
  • A measurement has been made for the radioactivities (or concentrations) of radon daughters, i.e., RaA, RaB and RaC in airborne dust by means of single filtering method. This is to evaluate the radioactivities in terms of Ci or WL (working level) from gross alpha counts measured in the selected-time intervals after an air sample is taken from a membrane filter paper with a mean pore size of $0.8{\mu}m$. This work involves determinations of standard deviation in radioactivities, radioactive equilibrium factor and ratio. It appears that a concentration of total radon daughters is $0.30{\sim}2.36pCi/l\;or\;0.89{\times}10^{-3}{\sim}6.57{\times}10^{-3}WL$, depending on the sampling time. Generally the highest concentration was observed around nine o'clock in a day while the lowest value was obtained around seventeen o'clock. Standard deviations based on counting statistics of RaA's, RaB's and RaC's concentrations are ${\pm}57.75%,\;{\pm}22.32%\;and\;{\pm}31.29%$, respectively. It is revealed that the radioactive equilibrium factor is 0.322 while the radioactive equilibrium ratio is of pattern $C_1>C_2>C_3$ in general. Here $C_1,\;C_2\;and\;C_3$ stand for concentrations of RaA,RaB and RaC, respectively.

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