• Journal of the Korean Magnetics Society
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• v.18 no.1
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• pp.28-31
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• 2008

We studied the effect of easy magnetization axis orientation with respect to the strip direction by measuring the magnetoresistance(MR), the magneto-optic Kerr effect(MOKE), and real-time domain evolution. The five strips were patterned on a single chip with the easy axis orientation of each strip relative to the longitudinal direction by around $0^{\circ}$, $18^{\circ}$, $36^{\circ}$, $54^{\circ}$ and $72^{\circ}$, respectively. The overall shape of field dependent MR was mostly governed by the anisotropy magnetoresistnace. The relative change of the longitudinal MR was significantly increased with increasing angle between the easy axis and strip direction, whereas, the transverse MR variation rate was decreased with increasing angle. Several MR steps were observed during the magnetization reversal, and the simultaneous measurement of the MOKE and the domain images identified that the MR steps were associated with evolution of the oppositely directed magnetic domain.

• Journal of ILASS-Korea
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• v.10 no.2
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• pp.1-9
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• 2005

An experimental study was carried out to obtain the fundamental data about the effects of radical ignition on premixture combustion. A CVC(constant volume combustor) divided into the sub-chamber and the main chamber was used. Numerous narrow passage holes are arranged between the main chamber and the sub-chamber. The products including radicals generated by spark ignition in tile sub-chamber derives the simultaneous multi-point ignition in the main chamber. We have examined the effects of the sub-chamber volume, the diameter and number of passage holes, and the equivalence $ratio({\Phi})$ on the combustion characteristics by means of burning pressure measurement and flame visualization. In a CVC, the overall burning time including the ignition delay became very short and the maximum burning pressure was slightly increased by the radical ignition(RI) method in comparison with those by the conventional spark ignition(SI) method. Combustible lean limit by RI method is extended by ${\Phi}=0.25$ compared with that by SI method. Also, In cases of charging the number and the diameter for the fixed total cross section of the passage holes, combustion period increased significantly at a sub-chamber with a single hole, but those of the other conditions had almost a similar tendency in the sub-chamber with 4 or more holes. regardless of equivalence ratio. Therefore, it was Proved that a critical cross section exists with the number of passage holes.

• The Korean Journal of Physiology and Pharmacology
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• v.5 no.1
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• pp.1-8
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• 2001

Hyperpolarization of arterial smooth muscle by acetylcholine is considered to be produced by the release of an unidentified chemical substance, an endothelium-derived hyperpolarizing factor (EDHF). Several chemicals have been proposed as the candidate for EDHF. However, none of them fulfil completely the nature and property of EDHF. Ultrastructural observation with electron microscope reveals that in some arteries, gap junctions are formed between endothelial and smooth muscle cells. In small arterioles, injection of gap junction permeable dyes into an endothelial cell results in a distribution of the dye to surrounding cells including smooth muscle cells. These observations allow the speculation that myoendothelial gap junctions may have a functional significance. Simultaneous measurement of the electrical responses in both endothelial and smooth muscle cells using the double patch clamp method demonstrates that these two cell types are indeed electrically coupled, indicating that they behave as a functional syncytium. The EDHF-induced hyperpolarization is produced by an activation of $Ca^{2+}-sensitive\;K^+-channels$ that are inhibited by charybdotoxin and apamin. Agonists that release EDHF increase $[Ca^{2+}]_i$ in endothelial cells but not in smooth muscle cells. Inhibition of gap junctions with chemical agents abolishes the agonist-induced hyperpolarization in smooth muscle cells but not in endothelial cells. All these observations can be explained if EDHF is an electrotonic signal propagating from endothelium to smooth muscle cells through gap junctions.

• Annals of Laboratory Medicine
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• v.38 no.6
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• pp.524-529
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• 2018

Background: An increase in neutrophil gelatinase-associated lipocalin (NGAL) indicates tubular injury. Diabetic nephropathy causes typical changes in the kidney, characterized by glomerulosclerosis and eventual tubular damage. We validated the usefulness of plasma NGAL (pNGAL) as a biomarker of tubular damage in patients with diabetic nephropathy. Methods: We included 376 patients with diabetes mellitus (260 patients with chronic renal insufficiency who had not received hemodialysis and 116 hemodialyzed due to diabetic nephropathy) and 24 healthy controls. Patients with chronic renal insufficiency were divided into three groups according to urinary albumin excretion (UAE) levels. pNGAL levels were measured using the Triage NGAL test (Alere, San Diego, CA, USA) and were compared between groups. We also examined whether pNGAL level was related to the degree of albuminuria and cystatin C-based glomerular filtration rate (GFR). Results: Mean pNGAL levels of the healthy controls, chronic renal insufficiency patients with diabetes mellitus, and hemodialyzed patients were $61.9{\pm}5.3ng/mL$, $93.4{\pm}71.8ng/mL$, and $1,536.9{\pm}554.9ng/mL$, respectively. pNGAL level increased significantly in patients with severe albuminuria (P <0.001) and had a moderate correlation with the degree of albuminuria (r=0.467; P <0.001) and GFR (r=0.519; P <0.001). Multivariate regression analysis showed that the pNGAL level was associated with tubular damage independent of patient age, sex, and GFR. Conclusions: pNGAL level independently reflects the degree of tubular damage in patients with diabetic nephropathy. Measurement of pNGAL, combined with UAE, would enable simultaneous, highly reliable assessments of tubular damage for such patients.

• Journal of International Academy of Physical Therapy Research
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• v.10 no.1
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• pp.1700-1705
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• 2019

Background: Mild cognitive impairment (MCI) is also called as aging related memory damage. Decreased cognitive function due to aging is known to be associated with the frontal lobe. Alpha wave is generated in the dominance in the frontal lobe or a wide range of regions in the brain, it should be doubted that the brain function might be degraded. Objective: To determine the effect of sensory stimulation type on learning and brain activity pattern of elderly persons with MCI. Design: Randomized Controlled Trial (single blind) Methods: Twenty elderly persons aged more than 65 with MCI were randonmized to simultaneous visual/auditory stimulation group (SVASG) and or auditory stimulation group (ASG). Ten peoples were assigned to each group and lectroencephalogram test was performed to individuals. In the electroencephalogram test, electroencephalography of prior to sensory stimulation, and during sensory stimulation were measured to compare brain activity pattern according to the study groups and measurement period. Results: The relative alpha power due to a sensory stimulation type showed that the SVASG significantly decreased in the left frontal lobe and the left parietal lobe statistically compared to those of the ASG while sensory stimulation was given (p<.05). The relative beta power due to a sensory stimulation type showed that the SVASG significantly increased in the left and right frontal lobes, the left and right parietal lobes, and the left temporal lobe statistically compared to those of the ASG while sensory stimulation was given (p<.05). Conclusions: Electroencephalographic analysis showed that the type of sensory stimulation can affect the brain activity pattern. However, the effects were not studied that which brain activity pattern help to improved cognitive function of elderly persons with mild cognitive impairment.

• Wind and Structures
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• v.11 no.1
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• pp.35-50
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• 2008

Wind and temperature have been shown to be the critical sources causing changes in the modal properties of large-scale bridges. While the individual effects of wind and temperature on modal variability have been widely studied, the investigation about the effects of multiple environmental factors on structural modal properties was scarcely reported. This paper addresses the modeling of the simultaneous effects of wind and temperature on the modal frequencies of an instrumented cable-stayed bridge. Making use of the long-term monitoring data from anemometers, temperature sensors and accelerometers, a neural network model is formulated to correlate the modal frequency of each vibration mode with wind speed and temperature simultaneously. Research efforts have been made on enhancing the prediction capability of the neural network model through optimal selection of the number of hidden nodes and an analysis of relative strength of effect (RSE) for input reconstruction. The generalization performance of the formulated model is verified with a set of new testing data that have not been used in formulating the model. It is shown that using the significant components of wind speeds and temperatures rather than the whole measurement components as input to neural network can enhance the prediction capability. For the fundamental mode of the bridge investigated, wind and temperature together apply an overall negative action on the modal frequency, and the change in wind condition contributes less to the modal variability than the change in temperature.

• Journal of the Korean Solar Energy Society
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• v.37 no.4
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• pp.23-33
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• 2017

A great deal of study for loss reduction of photovoltaic system is conducted currently. It is hard to distinct the fault of photovoltaic system with the naked eye. For that reason, it is essential to repair and maintain the PV system by monitoring the system. The fault of individual modules can cause the huge loss of the entire system because of the mismatch. Therefore, the method of diagnosing the PV array is necessary by measuring the multi-channel arrays simultaneously. In this paper, it is presented the method of measuring I-V curve of multi-channel arrays simultaneously by using the charge and discharge characteristics of capacitor. Generated DC power at PV arrays is charged and discharged at the capacitors in a moment. By measuring the charged voltage and current, it is possible to diagnose of performance of PV arrays.

• Korean Journal of Microbiology
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• v.55 no.3
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• pp.199-205
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• 2019

Yeast two-hybrid (Y2H) technique has been used to study protein-protein interactions, but its application particularly to a large-scale analysis of protein interaction networks, is limited by the fact that the technique is labor-intensive, based on scoring colonies on plate. Here, we develop a new reporter for the measurement of the protein-protein interactions by flow cytometry. The yeast harboring interacting proteins can also be enriched by fluorescence-activated cell sorting (FACS) or magnetic-activated cell sorting (MACS). When two interacting proteins are present in the same yeast cell, a reporter protein containing 10 tandem repeats of c-myc epitope becomes localized on the surface of the cell wall, without affecting cell growth. We successful measured the surface display of c-myc epitope upon interacting p53 with SV40 T antigen by flow cytometry. Thus, the newly developed Y2H assay based on the display of c-myc repeat on yeast cell wall could be used to the simultaneous analysis of multiple protein-protein interactions without laborious counting colonies on plate.

• Structural Engineering and Mechanics
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• v.69 no.2
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• pp.193-204
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• 2019

This paper presents results from experimental and numerical studies on the response of steel-concrete composite box bridge girders under certain localized fire exposure conditions. Two composite box bridge girders, a simply supported girder and a continuous girder respectively, were tested under simultaneous loading and fire exposure. The simply supported girder was exposed to fire over 40% of its span length in the middle zone, and the two-span continuous girder was exposed to fire over 38% of its length of the first span and full length of the second span. A measurement method based on comparative rate of deflection was provided to predict the failure time in the hogging moment zone of continuous composite box bridge girders under certain localized fire exposure condition. Parameters including transverse and longitudinal stiffeners and fire scenarios were introduced to investigate fire resistance of the composite box bridge girders. Test results show that failure of the simply supported girder is governed by the deflection limit state, whereas failure of the continuous girder occurs through bending buckling of the web and bottom slab in the hogging moment zone. Deflection based criterion may not be reliable in evaluating failure of continuous composite box bridge girder under certain fire exposure condition. The fire resistance (failure time) of the continuous girder is higher than that of the simply supported girder. Data from fire tests is successfully utilized to validate a finite element based numerical model for further investigating the response of composite box bridge girders exposed to localized fire. Results from numerical analysis show that fire resistance of composite box bridge girders can be highly influenced by the spacing of longitudinal stiffeners and fire severity. The continuous composite box bridge girder with closer longitudinal stiffeners has better fire resistance than the simply composite box bridge girder. It is concluded that the fire resistance of continuous composite box bridge girders can be significantly enhanced by preventing the hogging moment zone from exposure to fire. Longitudinal stiffeners with closer spacing can enhance fire resistance of composite box bridge girders. The increase of transverse stiffeners has no significant effect on fire resistance of composite box bridge girders.

• The Journal of the Korea institute of electronic communication sciences
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• v.15 no.6
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• pp.1037-1044
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• 2020

Since radar wind profiler (RWP) provides wind field data with high time and space resolution in all weather conditions, their verification of the accuracy and quality is essential. The simultaneous wind measurement from rawinsonde is commonly used to evaluate wind vectors from RWP. In this study, the simulation algorithm which produces the spectrum and raw time series (I/Q) data from the average values of moments is presented as a step-by-step verification method for the signal processing algorithm. The possibility of the simulation algorithm was also confirmed through comparison with the raw data of LAP-3000. The Doppler power spectrum was generated by assuming the density function of the skew-normal distribution and by using the moment values as the parameter. The simulated spectrum was generated through random numbers. In addition, the coherent averaged I/Q data was generated by random phase and inverse discrete Fourier transform, and raw I/Q data was generated through the Dirichlet distribution.