• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2003.11a
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• pp.306-330
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• 2003

The wet-end dynamics of a paper mill was analyzed to characterize its dynamic behavior during the grade change. The model representing the wet-end section is developed based on the mass balance relationships written for the simplified wet-end white water network. From the linearization of the dynamic model, higher-order Laplace transfer functions were obtained followed by the reduction procedure to give simple lower-order models in the form of $1^{st}$-order or $2^{nd}$-order plus dead times. The dynamic response of the wet-end is influenced both by the white water volume and by the level of wire retention. Effects of key manipulated variables such as the thick stock flow rate, the ash flow rate and the retention aid flow rate on the major controlled variables were analyzed by numerical simulations. The simple dynamic model developed in the present study can be effectively used in the operation and control.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.35 no.5
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• pp.26-36
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• 2003

The wet-end dynamics of a paper mill was analyzed to characterize its dynamic behavior during the grade change of paper. The model representing the wet-end section is developed based on the mass balance relationships written for the simplified wet-end white water network. From the linearization of dynamic model, higher-order Laplace transfer functions were obtained followed by the reduction procedure to give simple lower-order models in the form of 1$^{st}$-order or 2$^{nd}$ -order plus dead times. The dynamic response of the wet-end is influenced both by the white water volume and by the level of wire retention. Effects of key manipulated variables such as the thick stock flow rate, the ash flow rate and the retention aid flow rate on the major controlled variables were analyzed by numerical simulations. The simple dynamic model developed in the present study can be effectively used in the operation and control of paper mills.s.

• Journal of Microbiology and Biotechnology
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• v.15 no.6
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• pp.1377-1383
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• 2005

In a cDNA microarray experiment using Cy3 and Cy5 as labeling agents, particularly for the direct design, cDNAs from some genes incorporate one dye more efficiently than the other, which is referred to as the gene-specific dye bias. Dye-swaps, in which two dyes are switched on replicate arrays, are commonly used to control the gene-specific dye bias. We developed a simple procedure to extract the gene-specific dye bias information from a partial dye swap experiment. We detected gene-specific dye bias by identifying outliers in an X-Y plane, where the X axis represents the average log-ratio from two sets of dye swap pairs and the Y axis exhibits the average log ratio of four forward labeled arrays. We used this information for detecting differentially expressed genes, of which the additionally detected genes were validated by real-time RT-PCR.

• Earthquakes and Structures
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• v.19 no.3
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• pp.189-196
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• 2020

The near-collapse performance limit is defined as the deformation at the 20% drop of maximum base shear in the decreasing region of the pushover curve for ductile framed buildings. Although monotonic pushover analysis is preferred due to the simple application procedure, this analysis gives rise to overestimated results by neglecting the cumulative damage effects. In the present study, the acceptabilities of monotonic and cyclic pushover analysis results for the near-collapse performance limit state are determined by comparing with Incremental Dynamic Analysis (IDA) results for a 5-story Reinforced Concrete framed building. IDA is performed to obtain the collapse point, and the near-collapse drift ratios for monotonic and cyclic pushover analysis methods are obtained separately. These two alternative drift ratios are compared with the collapse drift ratio. The correlations of the maximum tensile and compression strain at the base columns and beam plastic rotations with interstory drift ratios are acquired using the nonlinear time history analysis results by the simple linear regression analyses. It is seen that these parameters are highly correlated with the interstory drift ratios, and the results reveal that the near-collapse point acquired by monotonic pushover analysis causes unacceptably high tensile and compression strains at the base columns, as well as large plastic rotations at the beams. However, it is shown that the results of cyclic pushover analysis are acceptable for the near-collapse performance limit state.

• 제어로봇시스템학회:학술대회논문집
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• 1993.10a
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• pp.233-238
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• 1993

In this paper, two diagnosis algorithms using the simple fuzzy, cognitive map (FCM) that is an useful qualitative model are proposed. The first basic algorithm is considered as a simple transition of Shiozaki's signed directed graph approach to FCM framework. And the second one is an extended version of the basic algorithm. In the extension, three important concepts, modified temporal associative memory (TAM) recall, temporal pattern matching algorithm and hierarchical decomposition are adopted. As the resultant diagnosis scheme takes short computation time, it can be used for on-line fault diagnosis of large scale and complex processes that conventional diagnosis methods cannot be applied. The diagnosis system can be trained by the basic algorithm and generates FCM model for every experienced process fault. In on-line application, the self-generated fault model FCM generates predicted pattern sequences, which are compared with observed pattern sequences to declare the origin of fault. In practical case, observed pattern sequences depend on transport time. So if predicted pattern sequences are different from observed ones, the time weighted FCM with transport delay can be used to generate predicted ones. The fault diagnosis procedure can be completed during the actual propagation since pattern sequences of tvo different faults do not coincide in general.

• Journal of Chest Surgery
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• v.29 no.10
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• pp.1152-1156
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• 1996

Cardiac tamponade Is an acute, life-threatening emergency, requiring immediate decompression by a safe and simple method. The most effective method of drainage has been controversial. We experienced successful outcome for the treatment of cardiac tamponade with drainage using the Seldinger technique. The causes of the cardiac tamponade were hemopericardium after mitral and aortic valve replacement and malignant pericardial effusion due to primary lung cancer. They were treated with emergency rainage by the Seldinger technique without procedure-related complications. We believe that this technique is simple, safe for the treatment of cardiac tamponade.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.23 no.3
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• pp.212-216
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• 2001

The cervical flap, comprising skin, fascia, and platysma muscle, has significant application in the head and neck region after radical ablative surgery for cancer of the oral cavity. The flap may be used for reconstruction of the cheek, floor of the mouth, and lateral side of the tongue. This flap minimizes donor morbidity by use of cervical operation wound and flap size available is adequate for most oral defects and the procedure is relatively simple and time-saving. However the flap is not applicable in patients where there are large tissue defects and metastasis is suspected. We have used the cervical flap for its rapid, simple, and effective closure of oral defects after cancer ablation and found it is very useful for the reconstruction of relatively small oral defects.

• Interaction and multiscale mechanics
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• v.2 no.4
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• pp.375-396
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• 2009

In the present work, the elasto-viscoplastic behavior, interactions between grains, and the texture evolution in polycrystalline materials subjected to finite deformations are modeled using a multiscale analysis procedure within a finite element framework. Computational homogenization is used to relate the grain (meso) scale to the macroscale. Specifically, a polycrystal is modeled by a material representative volume element (RVE) consisting of an aggregate of grains, and a periodic distribution of such unit cells is considered to describe material behavior locally on the macroscale. The elastic behavior is defined by a hyperelastic potential, and the viscoplastic response is modeled by a simple power law complemented by a work hardening equation. The finite element framework is based on a Lagrangian formulation, where a kinematic split of the deformation gradient into volume preserving and volumetric parts together with a three-field form of the Hu-Washizu variational principle is adopted to create a stable finite element method. Examples involving simple deformations of an aluminum alloy are modeled to predict inhomogeneous fields on the grain scale, and the macroscopic effective stress-strain curve and texture evolution are compared to those obtained using both upper and lower bound models.

• Archives of Pharmacal Research
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• v.21 no.3
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• pp.278-285
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• 1998

The microdilution assay recommended by NCCLS (National Committee for Clinical Laboratory Standards) is one of the standardized methods of antibiotic susceptibility test. This method has been widely used clinically to obtain MIC values of antibiotics on pathogenic microorganisms. It is more convenient, rapid and simple to test many samples than other test methods such as agar diffusion assay and broth macrodilution assay. The screening of antimicrobial agents from microbial extracts is too laborious in its process. Therefore, a number of screening methods having more simple procedure have been developed. In our laboratory, we applied microdilution assay for screening the antimicrobial agents. This assay showed dose-response results and was more sensitive than disc diffusion assay in our system. We tested 200 samples of microbial extracts originated from 100 microbial strains and selected several samples as potential candidates. In this report, we show that the microdilution assay is more convenient method in screeing of antibiotic susceptibility than those previously reported.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.49 no.4
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• pp.342-348
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• 2004

Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the $60\%$ isopropanol extract of soybean(Glycine max [L.] Merr.) seed revealed two abundant proteins with molecular masses of 19 and 10 kDa. Amino acid analysis revealed that the isopropanol-extractable protein fraction was rich in cysteine. Two-dimensional gel electro-phoretic analysis indicated that the 19kDa and 10kDa proteins had pI of 4.2 and 4.0 respectively. Peptide mass fingerprints of trypsin digests of the two proteins obtained using matrix-assisted, laser desorption/ionization-time of flight (MALDI-TOF) mass spectroscopy revealed the 19kDa protein was Kunitz trypsin inhibitor and the 10kDa protein was Bowman-Birk proteinase inhibitor. When resolved under non-denaturing conditions, the isopropanol-extracted proteins inhibited trypsin and chymotrypsin activity. Results presented in this study demonstrate that isopropanol extraction of soybean seed could be used as a simple and rapid method to obtain a protein fraction enriched in Kunitz trypsin and Bowman-Birk proteinase inhibitors. Since proteinase inhibitors are rich in sulfur amino acids and are putative anticarcinogens, this rapid and inexpensive isolation procedure could facilitate efforts in nutrition and cancer research.