• Journal of the Korean Institute of Telematics and Electronics
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• v.25 no.8
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• pp.867-873
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• 1988

The degradation due to channel distortion in a quadrature modulation system from the ideal constant values over the bandwidth of a direct sequence spread spectrum signal are considered. Through using series expansion for the channel gain and phase response, the degradation in the correlator output at the receiver is found as a function of the parameters involved , including phase error, delay error, linear gin variation, quadratic gain variation, and quadratic phase variation.

• Proceedings of the Korea Institute of Convergence Signal Processing
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• 2000.08a
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• pp.317-320
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• 2000

동영상 분할은 컴퓨터 비전 분야에서 중요한 단계로 많이 연구되고 있다 그러나 동영상 분할은 계산 복잡도에 의해 제약을 받는다. 이를 해결하기 위해, 본 논문은 분산 유전자 알고리즘에 기반한 계산 효율을 높일 수 있는 새로운 동영상 분할 방법을 제안한다. 일반적으로 동영상에서 연속한 두 프레임은 높은 상관관계를 가진다. 따라서, 한 프레임의 분할 결과는 이전 프레임의 분할 결과를 사용해서 연속적으로 얻어진다. 그리고 중복된 계산을 제거하기 위해 움직이는 객체에 대응되는 염색체만을 진화시킨다. 실험 결과는 제안한 방법의 효율성을 보여준다.

• Journal of Microbiology and Biotechnology
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• v.11 no.6
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• pp.915-921
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• 2001

Phytase improves the bioavailability of phytate phosphorus in plant foods to humans and animals, and reduces the phosphorus pollution of animal waste. In order to express a high level of fungal phytase in Saccharomyces cerevisiae, various expression vectors were constructed with different combinations of promoters, translation enhancers, signal peptides, and terminator. Three different promoters fused to the phytase gene (phyA) from Aspergillus niger were tested: a galactokinase (GAL1) promoter, glyceraldehyde-3-phosphate dehydrogenase (GPD) promoter, and yeast hybrid ADH2-GPD promoter consisting of alcohol dehydrogenase II (ADH2) and a GPD promoter. The signal peptides of phytase, glucose oxidase (GO), and rice amylase 1A(RAmy1A) were included. Plus, the translation enhancers of the ${\Omega}$ sequence and UTR70 from the tobacco mosaic virus (TMV) and spinach, respectively, were also tested. Among the recombinant vectors, pGphyA06 containing the GPD promoter, the ${\Omega}$ sequence, RAmy1A, and GAL7 terminator expressed the highest phytase activity in a culture filtrate, which was estimated at 20 IU/ml. An intracellular localization of the expressed phytase activity in a culture filtrate, which was estimated at 20 IU/ml. An intracellular localization of the expressed phytase was also performed by inserting an endoplasmic reticulum (ER) retention signal, KDEL sequence, into the C-terminus of the phytase within the vector pHphyA-6. It appeared that the KDEL sequence directed most of the early expression of phytase into the intracellular compartment yet more than $60\%$ of the total phytase activity was still retained within the cell even after the prolonged (>3 days) incubation of the transformant. However, the intracellular enzyme activity of the transformant without a KDEL sequence was as high as that of the extracellular one, thereby strongly suggesting that the secretion of phytase in S. cerevisiae appeared to be the rate-limiting step for the expression of a large amount of extracellular recombinant phytase, when compared with other yeasts.

• Journal of radiological science and technology
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• v.39 no.3
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• pp.345-352
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• 2016

The purpose of this study was to needed basis of measure MRI CAD development for signal to noise ratio (SNR) by pulse sequence analysis from region of interest (ROI) in brain magnetic resonance imaging (MRI) contrast. We examined images of brain MRI contrast enhancement of 117 patients, from January 2005 to December 2015 in a University-affiliated hospital, Seoul, Korea. Diagnosed as one of two brain diseases such as meningioma and cysts SNR for each patient's image of brain MRI were calculated by using Image J. Differences of SNR among two brain diseases were tested by SPSS Statistics21 ANOVA test for there was statistical significance (p < 0.05). We have analysis socio-demographical variables, SNR according to sequence disease, 95% confidence according to SNR of sequence and difference in a mean of SNR. Meningioma results, with the quality of distributions in the order of T1CE, T2 and T1, FLAIR. Cysts results, with the quality of distributions in the order of T2 and T1, T1CE and FLAIR. SNR of MRI sequences of the brain would be useful to classify disease. Therefore, this study will contribute to evaluate brain diseases, and be a fundamental to enhancing the accuracy of CAD development.

• Progress in Medical Physics
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• v.30 no.4
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• pp.139-149
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• 2019

Purpose: With neurodegeneration, the signal intensity of the cerebrospinal fluid (CSF) in the brain increases. The objective of this study was to evaluate chemical exchange saturation transfer (CEST) signals with and without the contribution of CSF signals in elderly human brains using two different 3T magnetic resonance imaging (MRI) sequences Methods: Full CEST signals were acquired in ten subjects (Group I) with a three-dimensional (3D)-segmented gradient-echo echo-planar imaging (EPI) sequence and in ten other subjects (Group II) with a 3D gradient and spin-echo (GRASE) sequence using two different 3T MRI systems. The segmented tissue compartments of gray and white matter were used to mask the CSF signals in the full CEST images. Two sets of magnetization transfer ratio asymmetry (MTR_asym) maps were obtained for each offset frequency in each subject with and without masking the CSF signals (masked and unmasked conditions, respectively) and later compared using paired t-tests. Results: The region-of-interest (ROI)-based analyses showed that the MTR_asym values for both the 3D-segmented gradient-echo EPI and 3D GRASE sequences were altered under the masked condition compared with the unmasked condition at several ROIs and offset frequencies. Conclusions: Depending on the imaging sequence, the MTR_asym values can be overestimated for some areas of the elderly human brain when CSF signals are unmasked. Therefore, it is necessary to develop a method to minimize this overestimation in the case of elderly patients.

• Journal of Microbiology and Biotechnology
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• v.9 no.5
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• pp.541-547
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• 1999

Constructions of a transfer vector and a recombinant baculovirus using the thymidine kinase gene of the Herpes simplex virus type 1 strain F (HSV -1) were carried out. Newly cloned transfer vector, pHcgXIIIB, was constructed by insertion of the glycoprotein gX gene signal peptide sequence of Pseudorabies virus into the baculovirus vector pHcEV-IV. The gX sequence was inserted just downstream from the promoter for the polyhedrin gene of the Hyphantria cunea nuclear polyhedrosis virus (HcNPV). HSV-1 thymidine kinase(tk) gene (1.131 kb) was used as a candidate gene for transferring into the baculovirus expression system. The tk gene was inserted into a BamHI site downstream from the gX sequence-promoter for the polyhedrin gene in the pHcgXIIIB transfer vector and was transferred into the infectious lacZ-HcNPV expression vector. Recombinant virus was isolated and was named gX-TK-HcNPV. The recombinant virus produced a 45 kDa gX-TK fusion protein in Spodoptera frugiperda cells, which was confirmed by Western blot analysis. Microscopic examination of gX-TK-HcNPV-infected cells revealed normal multiplication. Fluorescent antibody staining indicated that the gX-TK fusion protein was present in the cytoplasm. These results indicated that the transfer vector successfully transferred the gX-tk gene into the baculovirus expression system.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.4
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• pp.1976-1981
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• 2013

In this paper, we propose a frequency-domain interference cancellation algorithm for direct-sequence spread spectrum systems. In the previously proposed frequency-domain interference cancellation algorithms that protocol defines the rules concerning the collection of means of Transmission Control Protocol (TCP: Transmission Control Protocol) is the most widely used in the transport layer. Two-way traffic through the network path to the same end-to-end transfer of data in the opposite direction between pairs of nodes are infused with two or more TCP connection using the network traffic patterns from the exchanger and routers share results of approval. Per-flow input/output structure of matter using the LTS online reaction when evaluated as this is the most important factor. TCP-MT when the connection duration is one of the largest performance gains.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.4A
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• pp.288-295
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• 2005

OFDM communications system is very attractive for the high data rate wireless transmission. However, it may be distorted in the nonlinear HPA since OFDM signal has high PAPR. So, a new SLM method using dummy sequence is studied for reducing the PAPR, and we call it DSI-SLM method. Unlike the conventional SLM method using the phase rotation, dummy sequences for PAPR reduction are assigned at the predefined sub-carriers. After IFFT, the OFDM data signal of the lowest PAPR is selected to transmit. So, it can cut down the computational complexity because it does not require the transmission and demodulation process of side information about the phase rotation. This proposed method can solve the time delay problem so that PAPR reduction can be made in real time processing.

• Journal of Microbiology and Biotechnology
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• v.21 no.7
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• pp.667-674
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• 2011

The gene for esterase (rEst1) was isolated from a new species of genus Rheinheimera by functional screening of E. coli cells transformed with the pSMART/HaeIII genomic library. E. coli cells harboring the esterase gene insert could grow and produce clear halo zones on tributyrin agar. The rEst1 ORF consisted of 1,029 bp, corresponding to 342 amino acid residues with a molecular mass of 37 kDa. The signal P program 3.0 revealed the presence of a signal peptide of 25 amino acids. Esterase activity, however, was associated with a homotrimeric form of molecular mass 95 kDa and not with the monomeric form. The deduced amino acid sequence showed only 54% sequence identity with the closest lipase from Cellvibrio japonicus strain Ueda 107. Conserved domain search and multiple sequence alignment revealed the presence of an esterase/ lipase conserved domain consisting of a GXSXG motif, HGGG motif (oxyanion hole) and HGF motif, typical of the class IV hormone sensitive lipase family. On the basis of the sequence comparison with known esterases/ lipases, REst1 represents a new esterase belonging to the class IV family. The purified enzyme worked optimally at $50^{\circ}C$ and pH 8, utilized pNP esters of short chain lengths, and showed best catalytic activity with p-nitrophenyl butyrate ($C_4$), indicating that it was an esterase. The enzyme was completely inhibited by PMSF and DEPC and showed moderate organotolerance.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.11C
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• pp.1059-1065
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• 2007

In this paper, we propose a class of polyphase signature sequences, whose general odd correlation properties are useful for M-ary phase signaling systems. The maximum magnitude of the general odd correlation functions of the proposed sequences are investigated and compared with those of FZC (Frank-Zadoff-Chu) sequences and those of EOE (equivalent odd and even correlation) sequences. The performance of the asynchronous M-ary phase signaling systems using the proposed sequences is simulated and compared with that using FZC sequences in direct sequence code division multiple access (DS/CDMA) systems. The performance of the system using the proposed sequence is shown to be better than that using FZC sequences when the multipath fading is in existence.