• 수산해양교육연구
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• 제25권4호
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• pp.766-774
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• 2013

Biodegradable polybutylene succinate(PBS) is a kind of environmentally friendly plastics for fisheries, because it can mitigate the ghost fishing problem caused by gill-net and trap fisheries. To evaluate durability of PBS monofilament, each of different diameter 3 types of monofilaments were spun and exposed to 56 month outdoor and then their gravity, modification of surface, breaking strength, and elongation were analysed. The gravity of PBS monofilament was estimated to be approximately 1.24 when spinning ratio from 4.8 to 6.1. PBS monofilaments did not show any crack after 56 month exposed to outdoor and load-elastic elongation curve was showed sigmoid type. Decreasing ratio of elongation was appeared in the thinnest monofilament 0.2mm diameter and breaking strength was in the thickest monofilament 0.4mm diameter. Breaking strength and elongation at break were decreased rapidly after 48 month exposed to outdoor. Breaking strength reduced linearly after 48 month exposure, while no such linear relationship was found in the case of elongation at break. In results, it was investigated that the durability of PBS monofilament nets for gillnet and trap were 24, 50 month when keep to land, respectively.

• Structural Engineering and Mechanics
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• 제13권2호
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• pp.187-209
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• 2002

The infrastructure system in the United States has been aging faster than the resource available to restore them. Therefore decision for allocating the resources is based in part on the condition of the structural system. This paper proposes to use neural network to predict the overall rating of the structural system because of the successful applications of neural network to other fields which require a "symptom-diagnostic" type relationship. The goal of this paper is to illustrate the potential of using neural network in civil engineering applications and, particularly, in bridge evaluations. Data collected by the Tennessee Department of Transportation were used as "test bed" for the study. Multi-layer feed forward networks were developed using the Levenberg-Marquardt training algorithm. All the neural networks consisted of at least one hidden layer of neurons. Hyperbolic tangent transfer functions were used in the first hidden layer and log-sigmoid transfer functions were used in the subsequent hidden and output layers. The best performing neural network consisted of three hidden layers. This network contained three neurons in the first hidden layer, two neurons in the second hidden layer and one neuron in the third hidden layer. The neural network performed well based on a target error of 10%. The results of this study indicate that the potential for using neural networks for the evaluation of infrastructure systems is very good.

• 생명과학회지
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• 제28권3호
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• pp.351-356
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• 2018

L-세린 탈수화효소(LSD)는 L-serine을 피루브산과 암모니아로 전환하는 반응을 촉매하는 iron-sulfur 함유 효소이다. 세균성 아미노산 탈수화 효소 중에서, L-serine에 대한 이들 특정 효소만이 촉매 부위에서 iron-sulfur cluster를 이용하는 것으로 보고되고 있다. 또한, 세균성 LSD는 구조적 특성과 도메인의 배열에 따라 네 가지 유형으로 분류된다. 현재까지, 이 효소들은 소수의 균주로부터 얻어진 LSD 효소에 대해서만 연구되었지만, 다양한 세균성 LSD의 촉매 메커니즘을 이해하기 위해서는 더 많은 자세한 조사가 요구된다. 본 연구에서, Mycobacterium tuberculosis H37Rv로부터 유래된 유형 II LSD (MtLSD) 단백질을 효소 동력학적 방법을 이용하여 생화학적 및 촉매적 특성을 규명하기 위해 발현 및 정제되었다. MtLSD에 대한 L-serine의 포화 곡선은 알로스테릭 협동성(allosteric cooperativity)을 나타내는 전형적인 S자형(sigmoid)의 특성을 보였다. 이때의 $K_m$과 $k_{cat}$ 값은 각각 $59.35{\pm}1.23mM$과 $18.12{\pm}0.20s^{-1}$로 계산되었다. 또한, 고정된 L-serine 농도 하에서 D-serine의 농도 대비 초속도에 대한 그래프는 비선형 쌍곡선 감쇠 형태를 보였고, $k_{cat}$ 값의 변화 없이 $30.46{\pm}5.93mM$의 겉보기 $K_i$ 값으로 D-serine에 대한 경쟁적 억제(competitive inhibition)를 나타내었다. 이들 연구는 MtLSD의 촉매 특성 및 기질 특이성에 관한 통찰력 있는 생화학적 정보를 제공한다.

• 대한치과보철학회지
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• 제17권1호
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• pp.7-21
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• 1979

This investigation was to analyse normal protrusive and lateral condylar pantographic records written on the sagittal plane and to study components of Fisher's angle and their interrelations. The purpose of this study was limited to (1) discussing the significance of sagittal pantographic record in diagnosis of occlusal disease and(2) basing for reasoning validity of measuring Fisher's angle which has been reported so far. As a result followings were concluded. 1. In each protrusive and lateral condylar movement path, five complicate factors such as initial straightness, distributed simple sigmoid type, simple curvature, initial tiny protruding convexity and tiny repeated sigmoid patterns were noted. Generally each condylar movement path was composed of two to three of these factors. 2. The distribution of positional interrelations of protrusive and lateral condylar paths could be divided into five categories; (a) protrusive-upper, (b) completely coinciding, (c) partially initial coinciding, (d) partially inverted crossing, and (e) completely inverting. Among these, protrusive path-upper positioned condyles were prevailed (79.2%). 3. The distribution of interrelations of protrusive and lateral condylar paths could be devided into five categories according to their distances in the course of movement. Among these, opening (95.8%) and paralleling (66.7%) were prevailing. 4. The involved number of characteristic heterogenous patterns of five categories in protrusive and lateral condylar movement recording relations at one simultaneous recordings was limited to three. However, in case of homogeneous patterns were repeated, usually three to four were included. 5. The maximum distance between protrusive and lateral condylar paths was 1.45mm at the location of 4mm advanced position from centric relation point and 3.90mm at the location of protrusive movement terminal. 6. It seemed to be that ,pantographic records should be consulted other clinical symptoms in order to make certain occlusion diagnosis. 7. At the present moment of investigation, expressing Fisher's angle as a degree revealed a lack due to inherent complexity of protrusive and lateral condylar movement paths. 8. The typical pattern of protrusive and lateral condylar paths written on a pantographic sagittal plate might be described as follows; (a) protrusive condylar path should be positioned upwardly, (b) both mainly be simple curvature, (c) interrelations mainly be opening or paralleling. 9. The mean amounts of separation between protrusive and lateral condylar movement path were $0.75{\pm}0.46$ at 4mm advanced location from centric relation and $1.74{\pm}0.64mm$ at the location of protrusive path terminal.

• 지적과 국토정보
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• 제50권1호
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• pp.75-85
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• 2020

본 연구는 토지피복 분류에 사용 가능한 ROI 생성 과정에서 기계학습 기반 교차검증을 활용하였다. 연구지역은 세종시를 포함한 2019년 10월 28일 단시기 KOMPSAT-3A 영상을 활용하였다. 연구 과정에서 4개의 밴드(Red, Green, Blue, Near Infra-red)를 독립변수로 교차검증 과정에서 학습시켰다. 또한 SVM의 4가지 기법(Linear, Polynomial, RBF, Sigmoid)을 활용하여 추출된 ROI를 기반으로 토지피복 분류를 실시하였다. 교차검증 과정에서 훈련된 3,500개의 데이터 중 1,813개의 데이터가 추출되었으며 건물, 도로, 그리고 초지에서 약 60%의 데이터가 제거되었다. 추출된 ROI를 기반으로 다른 SVM기법에 비해 SVM Linear 기법이 91.77%로 가장 높은 분류 정확도를 나타냈다. 분류 클래스 중 초지의 경우 산림과의 오분류가 가장 많이 발생하며 79.43%의 생산자 정확도로 가장 낮은 분류 정확도를 보여주었다. 연구 결과에 따라 교차검증에서 추출된 ROI는 산림, 수역, 그리고 농업지역에 대해서는 90%이상의 분류정확도를 보여주며 효과적인 분류결과를 도출할 수 있었으나, 80%의 분류정확도를 보여주는 건물, 도로, 나대지, 그리고 초지 지역을 분류하는 방법에 대해서는 추가적인 연구가 진행되어야 할 필요성이 존재한다.

• Imaging Science in Dentistry
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• 제38권3호
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• pp.153-161
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• 2008

Purpose : To compare and evaluate the diagnostic ability of cone beam computed tomography (CBCT) and magnetic resonance imaging (MRI) of the temporomandibular joint (TMJ). Materials and Methods : CBCT and MRI of 46 TMJs of 23 patients with TMJ disorders were evaluated. They were divided into 3 groups according to the position of the articular disc of the TMJ at closed mouth position and the reduction of the disc during open mouth position on MRI: no disc displacement group (NDD), disc displacement with reduction group (DDR), and disc displacement without reduction group (DDWR). With PACS viewing soft-wares, position of mandibular condyle in the articular fossa, osseous change of mandibular condyle, shape of articular fossa, and mediolateral and anteroposterior dimensions of mandibular condyle were evaluated on CBCT and MRI. Each value was tested statistically. Results : The position of mandibular condyle in the articular fossa were concentric in the NDD, DDR, and DDWR of CBCT and NDD of MRI. However, condyle was positioned posteriorly in DDR and DDWR of MRI. Flattening, sclerosis and osteophyte of the mandibular condyle were much more apparent on DDR of CBCT than MRI. And the erosion of the condyle was much more apparent on DDWR of MRI than CBCT. Box and Sigmoid types of articular fossa were found most frequently in DDR of MRI. Flattened type was found most frequently in DDR of CBCT and deformed type was found most frequently in DDWR of CBCT. No significant difference in mediolateral and anteroposterior dimensions were shown on CBCT and MRI. Conclusion : Since MRI and CBCT has unique diagnostic imaging ability, both modalities should be used together to supplement each other to evaluate TMJ.

• 한국초지조사료학회지
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• 제11권4호
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• pp.209-214
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• 1991

수분 장애시 목초 발아 특성을 검토하기 위하여, 삼투압 0, -5 bar 두 수준에서 tall fescue, orchardgrass, Kentucky bluegrass 및 alfalfa의 총 발아율, 발아속도계수를 구하였으며, 누적 발아율의 경시적인 변화를 logistic 및 Weibull 함수를 이용하여 비선형회귀 잔차에 의하여 함수간 비교를 하였고, 각 함수로부터 추정된 계수를 조사 하였던바 다음과 같은 결과를 얻었다. 1. 삼투압 수준 -5 bar에서 대조구 대비 총발아율은 감소, 발아속도계수는 감소하였으며, alfalfa는 다른 초종에 비하여 그 변화정도가 적었다. 2.비총형회귀잔차 분석에 의하면 tall fescue, Kentucky bluegrass 및 orchardgrass는 삼투압 조건에 관계없이 logistic과 Weibull 함수간에 차이가 없었으나, Weibull 함수에 의한 alfalfa의 누적 발아율 곡선추정시 분석잔차가 logistic 함수보다 적었다. 3. 각 함수로 부터 20% 발아율 도달 일수를 추정한바, 수분장애에 의한 발아지연을 감지할 수 있었으며 함수들간의 유의적인 차이가 인정되었다. 4. logistic 함수로부터 추정된 비율계수는 alfalfa를 제외한 전 초종에서 수분장애에 의해 감소되었고, Weibull 함수로 부터 추정된 규모 및 형상 계수는 일반적으로 증가하는 경향이었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9649-9654
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• 2014

Background: Polyps are common lesions in the gastrointestinal (GI) tract. Colon cancer is mostly a result of progression from polyps. The present study aimed to evaluate demographic, clinical, and histological characteristics of colorectal polyps in Iran, particularly neoplastic and advanced types. Materials and Methods: Over a period of 10 years, specimens of all colorectal polyps obtained from colonoscopy were studied. The variables subjected to statistical analysis were age, sex, and the chief clinical complaint of the patients who underwent colonoscopy, their motivation, and the site, size, and histological types of detected polyps. The level of significance was set at p value <0.05. Results: Data were obtained from a total of 352 patients. No difference was seen between male and female patients regarding histological types. Only in nine patients was screening the reason for colonoscopy. Almost two-thirds (66.2%) of the polyps were neoplastic. Familial polyposis syndrome and inflammatory bowel disease were seen in 4.3% and 3.0% of the patients with neoplastic polyps, respectively. Sites of polyps were the sigmoid, rectum, and descending colon in 40.1%, 34.5%, and 17% of the cases, respectively. The advanced type made up 58.8% of neoplastic polyps. Only 3.6% of the patients undergoing colonoscopy in the study period had biopsied polyps. Discussion: No difference was observed between male and female patients in terms of overall incidence of polyps, histological and anatomical profiles, and mean age distribution. Anatomical and histological profiles agreed with the studies performed in areas with a low risk of colon cancer. The findings show that colonoscopy was not performed when it was necessary. A meaningful increase in the number polyp biopsy cases and a corresponding decrease in polyp size in the last few years of the study can be associated with the presence of more GI specialist clinicians in hospital centers, and this holds out much hope for the further improvement of the situation in the future.

• Asian Pacific Journal of Cancer Prevention
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• 제16권11호
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• pp.4647-4652
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• 2015

Background: Colorectal cancer (CRC) is becoming one of the most complicated challenges of human health, particularly in developing countries like Iran. In this paper, we try to characterize CRC cases diagnosed < age 50 at-risk for Lynch syndrome within central Iran. Materials and Methods: We designed a descriptive retrospective study to screen all registered CRC patients within 2000-2013 in Poursina Hakim Research Center (PHRC), a referral gastroenterology clinic in central Iran, based on being early-onset (age at diagnosis ${\leq}50years$) and Amsterdam II criteria. We calculated frequencies and percentages by SPSS 19 software to describe clinical and family history characteristics of patients with early-onset CRC. Results: Overall 1,659 CRC patients were included in our study of which 413 (24.9%) were ${\leq}50years$ at diagnosis. Of 219/413 successful calls 67 persons (30.6%) were reported deceased. Family history was positive for 72/219 probands (32.9%) and 53 families (24.2%) were identified as familial colorectal cancer (FCC), with a history of at-least three affected members with any type of cancer in the family, of which 85% fulfilled the Amsterdam II Criteria as hereditary non-polyposis colorectal cancer (HNPCC) families (45/219 or 20.5%). Finally, 14 families were excluded due to proband tumor tissues being unavailable or unwillingness for incorporation. The most common HNPCC-associated extracolonic-cancer among both males and females of the families was stomach, at respectively 31.8 and 32.7 percent. The most common tumor locations among the 31 probands were rectum (32.3%), sigmoid (29.0%), and ascending colon (12.9%). Conclusions: Given the high prevalence of FCC (~1/4 of early-onset Iranian CRC patients), it is necessary to establish a comprehensive cancer genetic counseling and systematic screening program for early detection and to improve cancer prognosis among high risk families.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제20권2호
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• pp.94-99
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• 2017

Purpose: Abdominal cysts of gastrointestinal origin are rare. Their rarity and varied clinical presentations make their pre-operative diagnosis difficult. Methods: Fourteen patients with histological diagnosis of cysts of gastrointestinal origin admitted between 2009 and 2015 were retrospectively analyzed with respect to age, sex, clinical presentation, diagnostic modality, site and type of cyst, management, outcome and follow-up. Results: The mean age at presentation was 4 years and there were six males and eight females. Abdominal pain was the most common presenting symptom. Five patients had an acute presentation-three had distal ileal mesenteric cysts and two had ileal duplication cyst sharing a common wall with ileum. Six patients presented with chronic abdominal pain and lump-three patients had omental cysts and three had mesenteric cysts-two of these in distal ileum and one in sigmoid colon. Two patients presented with antenatally diagnosed palpable abdominal lump. One had a mesenteric cyst of the ileum and the other had a distal ileal duplication cyst which required excision with resection and anastomosis. One patient had an atypical presentation. He was a known case of sickle cell trait and had presented with vague abdominal pain, recurrent cough and multiple episodes of haemoptysis over a period of one year. At laparotomy, gastric duplication cyst was found which was excised completely. Histopathology confirmed the diagnosis. Conclusion: Cysts of gastrointestinal origin are rare and have varied presentation. Surgical excision is the mainstay of treatment. The results and prognosis are good.