• Korean Journal of Clinical Pharmacy
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• v.33 no.1
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• pp.43-50
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• 2023

Background and Objective: With the advancement of cancer treatments and increased life expectancy, managing breakthrough cancer pain (BTcP) is essential to improve the quality of life for cancer patients. This study aimed to compare the major rapid onset opioids in Korea based on their characteristics and costs to determine the best option for each patient. Methods: Based on sales information from IQVIA-MIDAS, sublingual fentanyl tablet (SLF), fentanyl buccal tablet (FBT), and oral transmucosal fentanyl citrate (OTFC) were selected as the top three drugs for the treatment of BTcP in Korea, considering them the most comparable drugs. The cost and cost-pain relief ratio of the drugs for short-term (1 month) and long-term (1 year) treatment were compared and the ease of administration based on various factors, including pharmacokinetics, onset of action, and administration procedures were evaluated. Results: SLF was evaluated as the best overall in terms of rapid onset of action, ease of administration, and drug cost and also had the highest market share. SLF had the lowest cost pain relief ratio for both the initial and supplemental treatment for the 1-month pain intensity difference 15 (PID15) ratio. However, for the 1-month PID30 ratio, SLF was not superior to OTFC or FBT. The longer the breakthrough cancer pain duration, the more cost-effective the other rapid onset opioids. Conclusion: The rapid onset opioids that fit the patient's breakthrough cancer pain pattern have the best cost-effectiveness.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.11 no.6
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• pp.49-59
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• 2012

Recently, various alternatives for safety and efficiency of commercial vehicles have been considered, and one of the new alternatives is the application of a digital tachograph. In Korea, the installation of a digital tachograph to commercial vehicles was regulated from 2011 and Korea Transportation Safety Authority developed e-TAS to analyze the monitoring data from digital tachographs installed in the order of 100 commercial vehicles. This study performs the potential impact analysis of the DTG installation, which includes a trend of dangerous driving, a trend of traffic accidents and cost-effective analysis, a trend of fuel consumption and cost-effective analysis, a cost-effective analysis of social benefits using e-TAS data. Depending on the frequency of dangerous driving, the participants are divided into three groups; high-dangerous group, average-dangerous group and low-dangerous group. The high-dangerous driving group shows lower km/liter than the low-dangerous driving group by 15% for buses and taxis and by 30% for trucks. About $CO_2$ emission, the difference becomes bigger; 25%, 25% and 42% for buses, taxis and trucks, respectively. Although this study is a short-term period analysis, the methodology will be applicable for the long-term period analysis with larger data.

• Journal of Electrical Engineering and Technology
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• v.11 no.6
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• pp.1645-1655
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• 2016

A Dynamic Voltage Restorer (DVR) model is proposed to eliminate the short-term voltage disturbances that occur in the grid-connected mode, the switching between grid-connected mode and the stand-alone mode of a Microgrid. The proposed DVR structure is based on a conventional cascaded H-bridge multilevel inverter (MLI) topology; a novel composite control strategy is presented, which could ensure the compensation ability of voltage sag by the DVR. Moreover, the compensation to specified order of harmonic is added to implement effects that zero-steady error compensation to harmonic voltage in specified order of the presented control strategy; utilizing wind turbines-batteries units as DC energy storage components in the Microgrid, the operation cost of the DVR is reduced. When the Microgrid operates under stand-alone mode, the DVR can operate on microsource mode, which could ease the power supply from the main grid (distribution network) and consequently be favorable for energy saving and emission reduction. Simulation results validate the robustness and effective of the proposed DVR system.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2015.07a
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• pp.171-172
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• 2015

Vinalines is actually known as not only one of Vietnam's state-sponsored economic giants but also the largest shipowner by tonnage in Vietnamese shipping industry. Therefore, a question of how to improve business performance of the corporation is always received deep attention by Vietnamese government, specially after the seriously economic scandal of Vinalines in a last few years. Among development strategies, the study focuses on short-term one in which Vinalines is recommended to restructure its own fleet in order to optimize performance of fleet operation and minimize costs while meeting the customer's shipping demand in near future. The first section is of introduction. Via method of statistical data analysis, section 2 brings to readers a panorama about the development profile and the current situation of development of Vinalines. In section 3, the authors use linear programming for setting a cost-minimization model optimizing Vinalines fleet structure based on available statistics and forecast information by Vinalines. The optimization problem is solved by applying AIMMS software in section 4. Finally, some conclusions and proposals by authors for the development of Vinalines are given.

• Proceedings of the Korean Geotechical Society Conference
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• 2006.03a
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• pp.434-444
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• 2006

The stone column method is widely used in Europe as an alternative to conventional pile foundations. Several benefits of using the stone column method include sound performance, low cost, expediency of construction, and liquiefaction resistance, among others. Recently, geosynthetic-encased stone column approach has been developed to improve its' load carrying capacity through increasing confinement effect. Although such a concept has successfully applied in practice, fundamentals of the method have not been fully explored. This Paper Presents the results of an investigation on the loading carriying capacity of geogrid-encased stone column using a series of 2D finite element analyses. The results of the analyses indicated improved short- and long-term carrying capacity of the geogrid-encased stone column method over the conventional strone column method with no encasing.

• Korean Journal of Agricultural Science
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• v.40 no.4
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• pp.385-394
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• 2013

Short-term agricultural machinery rental system has been operated by agricultural extension organization of local government (agricultural technology center) and sponsored by Ministry of Agriculture, Food, and Rural Affairs, to improve utilization efficiency and save agricultural production cost through joint utilization of agricultural machinery. This study was conducted to analyze current status of the rental system operation and provide recommendations for future direction. Question survey was conducted for officers in charge of the rental system in the technology center, and strategic improvement was suggested through importance performance analysis (IPA). Survey results showed that 11 issues should be reformed or improved by 2015, which is not practically feasible. IPA analysis resulted that administration and manpower support, cooperation between federal and local organizations, and cooperation with other organizations should be focused for successful operation of the rental system. Issues that seem to happen after 2015 need to be handled as future research.

• The Transactions of the Korean Institute of Electrical Engineers
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• v.41 no.8
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• pp.831-840
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• 1992

This paper presents an efficient short-term generation scheduling method using a rule-based expert/consulting system approach to assist electric energy system operators and planners. The expert system approach is applied to improve the Dynamic Programming(DP) based generation scheduling algorithm. In the selection procedure of the feasible combinations of generating units at each stage, automatic consulting on the manipulation of several constraints such as the minimum up time, the minimum down time and the maximum running time constraints of generating units will be performed by the expert/consulting system. In order to maximize the solution feasibility, the aforementioned constraints are controlled by a rule-based expert system, that is, instead of imposing penalty cost to those constraint violated combinations, which sometimes may become the very reason of no existing solution, several constraints will be manipulated within their flexibilities using the rules and facts that are established by domain experts. In this paper, for the purpose of implementing the consulting of several constraints during the dynamic process of generation scheduling, an expert system named STGSCS is developed. As a building tool of the expert system, C Language Integrated Production System(CLIPS) is used. The effectiveness of the proposed algorithm has been demonstrated by applying it to a model electric energy system.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.8
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• pp.2993-3010
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• 2021

The job shop scheduling problem (JSSP) plays a critical role in smart manufacturing, an effective JSSP scheduler could save time cost and increase productivity. Conventional methods are very time-consumption and cannot deal with complicated JSSP instances as it uses one optimal algorithm to solve JSSP. This paper proposes an effective scheduler based on deep learning technology named self-supervised long-short term memory (SS-LSTM) to handle complex JSSP accurately. First, using the optimal method to generate sufficient training samples in small-scale JSSP. SS-LSTM is then applied to extract rich feature representations from generated training samples and decide the next action. In the proposed SS-LSTM, two channels are employed to reflect the full production statues. Specifically, the detailed-level channel records 18 detailed product information while the system-level channel reflects the type of whole system states identified by the k-means algorithm. Moreover, adopting a self-supervised mechanism with LSTM autoencoder to keep high feature extraction capacity simultaneously ensuring the reliable feature representative ability. The authors implemented, trained, and compared the proposed method with the other leading learning-based methods on some complicated JSSP instances. The experimental results have confirmed the effectiveness and priority of the proposed method for solving complex JSSP instances in terms of make-span.

• Smart Structures and Systems
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• v.32 no.5
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• pp.297-308
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• 2023

Dynamic deflection is important for evaluating the performance of a long-span cable-stayed bridge, and its continuous measurement is still cumbersome. This study proposes a dynamic deflection monitoring method for cable-stayed bridge based on Bi-directional Long Short-term Memory (BiLSTM) neural network taking advantages of the characteristics of spatial variation of cable acceleration response (CAR) and main girder deflection response (MGDR). Firstly, the relationship between the spatial and temporal variation of the CAR and the MGDR is described based on the geometric deformation of the bridge. Then a data-driven relational model based on BiLSTM neural network is established using CAR and MGDR data, and it is further used to monitor the MGDR via measuring the CAR. Finally, numerical simulations and field test are conducted to verify the proposed method. The root mean squared error (RMSE) of the numerical simulations are less than 4 while the RMSE of the field test is 1.5782, which indicate that it provides a cost-effective and convenient method for real-time deflection monitoring of cable-stayed bridges.

• Journal of Intelligence and Information Systems
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• v.22 no.2
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• pp.13-31
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• 2016

Despite expectations of short- or long-term positive effects of corporate social responsibility (CSR) on firm performance, the results of existing research into this relationship are inconsistent partly due to lack of clarity about subordinate CSR concepts. In this study, keywords related to CSR concepts are extracted from atypical sources, such as newspapers, using text mining techniques to examine the relationship between CSR and firm performance. The analysis is based on data from the New York Times, a major news publication, and Google Scholar. We used text analytics to process unstructured data collected from open online documents to explore the effects of CSR on short- and long-term firm performance. The results suggest that the CSR index computed using the proposed text - online media - analytics predicts long-term performance very well compared to short-term performance in the absence of any internal firm reports or CSR institute reports. Our study demonstrates the text analytics are useful for evaluating CSR performance with respect to convenience and cost effectiveness.