• Korean Journal of Veterinary Research
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• v.49 no.2
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• pp.113-119
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• 2009

Atrophic rhinitis (AR) is the one of important respiratory diseases and causes severe economic losses in pig industry. Severe attempts have been made to reduce the economic losses by preventing the disease. One of the methods is the spraying of antibiotics into nasal cavity of piglets. Recently, the efficacy of the spraying with kanamycin and gentamicin was reduced in the Korean swine industry. Therefore, the preventive methods have been required to be changed based on the antimicrobial susceptibility profiles of causative agents of swine AR. Based on the current situations of this disease, Bordetella (B.) bronchiseptica and Pasteurella (P.) multocida 4D were isolated from pigs with clinical signs of AR. The isolation rates of B. bronchiseptica and P. multocida 4D were 58.5% and 32.9%, respectively. In the antimicrobial susceptibility test, the bacteria were resistant to kanamycin and gentamicin which have been used as the spraying agents, but they were susceptible to amikacin. A new spraying agent was developed using amikacin using ${\beta}$-glucan and yakbaltag as supplementary agents. Field efficacy of the agent was carried out with different schedule. The results from this study suggested that the newly developed spraying agents might be helpful to prevent AR in swine.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.28 no.6
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• pp.677-684
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• 2004

Plastic and creep deformations of solder joints during thermal cycling are the main factors of misalignments and power losses in optical telecommunication components. Furthermore, the increased mismatch between solder Joint-bonded areas may cause severe failure in the components. Darveaux's creep model was implemented into a finite element program (ABAQUS) to simulate creep response of solder. Based on the finite element results, thermal fatigue reliability was predicted by using various fatigue life prediction models. Also, the effects of ramp conditions, dwelling time, and solder joint-embedding materials on the reliability were investigated under the thermal cycling conditions of the Telcordia schedule (-40∼75$^{\circ}C$).

• Proceedings of the KSME Conference
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• 2001.11b
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• pp.837-841
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• 2001

Almost all power plant boiler has temperature distribution nonuniformity problem in heat transfer tube flow path. It can cause hot spot damage of superheated or reheated heat transfer section and reduce maintenance schedule when nonuniformity is severe. There are two solutions for improvement temperature nonuniformity. one is change of gas flow distribution of gas path and the other is contorl steam flow in tube bank. Of course, first method is very difficulty to apply but second method is'nt. In this paper, control steam flow is used to solve temperature nonuniformity of power plant boiler.

• Nuclear Engineering and Technology
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• v.45 no.6
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• pp.791-794
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• 2013

Since the Fukushima accident in 2011, the importance of the electrical systems in nuclear power plants (NPPs) has been emphasized. The result has been that NPP regulators are enhancing their monitoring of loss of offsite power (LOOP) events. Korea Hydro & Nuclear Power Co. (KHNP) is reviewing the status and issues related to LOOPs, and is attempting to establish specific countermeasures to prevent LOOPs, because they can have severe consequences in the complicated maintenance schedule during an outage. A starting point for preventing LOOPs is the control of the loss of voltage (LOV)-initiating components. In order to reflect this in the risk assessment program, an LOV monitor is being developed for use during plant outages.

• Journal of information and communication convergence engineering
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• v.8 no.4
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• pp.393-398
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• 2010

For multi-cell environments, coordinated random beamforming technique in multiuser MIMO(multiple-input multiple-output) broadcast channel is considered. In order to mitigate severe interference at receivers, the multi-cell environments might require complex transmitter and receiver design because the scheduler decision based on full channel state information (CSI) in one cell must be intertwined with decision made by other cells' CSI. With limited CSI, however, this paper considers a scheme of randomizing transmitters' beamforming but being coordinated with other cell transmitters. The transmitters in each cell share random beamforming patterns and schedule data transmission within coherent scheduling period. The corandomized beams allow the users to be selected with the highest SINRs even in multi-cell environments. We analyze the performance of the proposed scheme. And numerical results show that the scheme achieves better performance than the conventional random beamforming when applying to multi-cell environments.

• Journal of Chest Surgery
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• v.27 no.5
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• pp.407-412
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• 1994

Congenital long-segment tracheal stenosis which involves nearly entire trachea and carina is very rare disease, but leads to life threatening obstruction in infancy and childhood. Symptoms are ranged from stridor and wheezing to severe cyanosis and respiratory failure. Routine chest X-ray is somewhat helpful to diagnose it, but definitive diagnosis can be made by bronchoscopy or tracheogram for severely narrowed tracheal lumen.Recently, we experienced a case of congenital tracheal stenois, type 1 by Cantrell classification with carinal involvement. After costal cartilage was designed as oval shaped flap and covered with pericardium, anterior and posterior augmentation was done with prepared costal cartilage.This patient died of respiratory failure at 13 days postoperatively, probably due to sustaining obstruction in association in with failure to make a sufficient widening at carinal level.Important issues in the management of congenital tracheal stenosis are rapid diagnosis, selection of appropriate surgical procedure, and detailed anesthetic schedule.In the future, more biocompatible material and more effective surgical procedures should be studied to reduce the surgical mortality and morbidity of the complicated tracheal stenosis.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1781-1786
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• 2013

Objective: The study was designed to assess the skin and subcutaneous toxicity in patients with advanced colorectal carcinoma treated with four different schedules of FOLFOX. Methods: The patients with histologically confirmed advanced colorectal carcinoma (CRC) were included in the study as per specified inclusion criteria. Toxicity was graded according to CTC v2.0. The frequency of grade 3 and 4 adverse effects were comparatively assessed in each treatment arm. Results: Very severe toxicity was attributed to the FOLFOX7 schedule. The difference between the incidence rate of grade 4 toxicity with all other grades for all parameters of skin and subcutaneous toxicity was highly significant (p=0.00<0.001). Grade 4 hand and foot syndrome was reported only in the FOLFOX7 treatment arm. The most frequent adverse symptom of skin and subcutaneous toxicity reported in the patients treated with modified schedule of FOLFOX was pruritus (grade 1). Frequency and onset of skin and subcutaneous toxic symptoms like alopecia (p=0.000), nail discoloration (p=0.021) and pruritis (p=0.000) was significantly different in each FOLFOX treatment arm. A few cases of oncholysis were also reported in the FOLFOX7 treatment arm. Hand and foot syndrome was fast progressing in patients with grade 1 toxicity. Conclusion: Higher frequency and severity of hand and foot syndrome and pruritus wasa found in the FOLFOX7 treatment arm. Skin and subcutaneous toxicity was comparatively low in the FOLFOX6 treatment arm.

• Journal of Oriental Neuropsychiatry
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• v.15 no.2
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• pp.45-51
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• 2004

Hwabyung is a Korean culture bound syndrome and translated as anger syndrome at DSM-IV. And it is caused by the suppression of anger and has characteristics of chest discomfort, burning up as physical symptoms, and mortification, chagrin as psychological symptoms. It is very common in the field of psychiatry in Korea with Major Depressive Disorder (MDD). * Objective : 95 patients with MDD or Hwabyung, who visited the department of psychiatry in Korea University Medical Center or oriental medical hospital of Kyunghee Medical Center from May 2003 to August 2003, were selected for the study to compare between Major Depressive Disorder and Hwabyung. * Methods : The Structured Clinical Interview Schedule for DSM-IV (SCID) and Hwa-Byung Diagnostic Interview Schedule (HBDIS) were conducted for diagnosis. And Symptom Check List-90-Revised (SCL-90-R) was carried out for comparison between MDD and Hwabyung. * Result : Among the 95 patients, MDD group was 23 persons, Hwabyung group was 36 persons, and MDD plus Hwabyung group was 36 persons and it occupied 37.9%. MDD plus Hwabyung group had higher scores than any other groups in the whole dimensions of SCL-90-R. Hwabyung group had higher scores than MDD group in somatization, anxiety, hostility, Global Severity Index(GSI) and positive symptom total (p<.05) of SCL-90-R, but two groups had no difference in obsessive-compulsive, interpersonal-sensitivity, depression, phobic anxiety, paranoid ideation, psychoticism, positive symptom distress index of SCL-90-R. * Conclusion : These result showed that Hwabyung is similar to MDD at the point of depression and psychoticism but more severe at somatization, anxiety and anger than MDD.

• Journal of the Korean Wood Science and Technology
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• v.35 no.1
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• pp.11-16
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• 2007

This study was carried out to investigate the effect of Vapor-dam treatment on drying drying rates, prevention of checks and V-shaped split during air circulating oven drying bamboo (Phyllostachys pubescens Mazel et Z) tube. It was shown that the drying time from green to around 7~8 % of moisture content was required less as drying schedule was more severe, and distinctly dominated by the drying rate during the initial drying stage. Area shrinkages in cross section and thickness shrinkages measured during air circulating oven drying test were very large. Surface checks and V-shaped splits were occurred in untreated samples just after the beginning of drying, while sixty seven percentages of all the Vapor-dam treated samples could be produced without drying defects. The V-shaped splits occurred in the Vapor-dam treated samples were influenced more by the sealing of the vapor evaporation through the cross section than drying schedule.

• Clinical and Experimental Vaccine Research
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• v.12 no.4
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• pp.337-345
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• 2023

Purpose: The global fight against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has led to widespread vaccination efforts, yet the optimal dosing schedule for SARS-CoV-2 vaccines remains a subject of ongoing research. This study aims to investigate the effectiveness of administering two booster doses as the third and fourth doses at different intervals to enhance vaccine protection. Materials and Methods: This study was conducted at a military regional hospital operated by the Ministry of National Defense in Taiwan. A cohort of vaccinated individuals was selected, and their vaccine potency was assessed at various time intervals following their initial vaccine administration. The study participants received booster doses as the third and fourth doses, with differing time intervals between them. The study monitored neutralizing antibody titers and other relevant parameters to assess vaccine efficacy. Results: Our findings revealed that the potency of the SARS-CoV-2 vaccine exhibited a significant decline 80 days after the initial vaccine administration. However, a longer interval of 175 days between booster injections resulted in significantly higher neutralizing antibody titers. The individuals who received the extended interval boosters exhibited a more robust immune response, suggesting that a vaccine schedule with a 175-day interval between injections may provide superior protection against SARS-CoV-2. Conclusion: This study underscores the importance of optimizing vaccine booster dosing schedules to maximize protection against SARS-CoV-2. The results indicate that a longer interval of 175 days between the third and fourth doses of the vaccine can significantly enhance the neutralizing antibody response, potentially offering improved protection against the virus. These findings have important implications for vaccine distribution and administration strategies in the ongoing battle against the SARS-CoV-2 pandemic. Further research and largescale trials are needed to confirm and extend these findings for broader public health implications.