• YAKHAK HOEJI
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• v.45 no.1
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• pp.108-115
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• 2001

We have recently reported the development of a high efficiency expression vector, pCK, which can drive a high level of gene expression in mouse skeletal muscle. In this study, we tested the therapeutic potential of pCK expressing human VEGF165, pCK-VEGF in the rabbit ischemic hind limb model. To determine the optimal dose of plasmid DNA, various concentrations of pCK-CAT were injected into the muscle of a rabbit hind limb and the levels of CAT activity were determined. It was found that the expression level of the exogenously added gene became stable between 250 and 1,000 $\mu$g. Based on this result, we tested whether intramuscular transfer of 500$\mu$g of pCK-VEGF could actually modulate collateral vessel development in a rabbit ischemic hind limb model. It was found that relative to the control group injected with the pCK lacking the VEGF sequence, single intramuscular doses (500$\mu$g) of pCK-VEGF produced statistically significant augmentation of collateral vessels as determined by the angiographic vessel count, maximal blood flow by Doppler flowmeter and the number of capillaries by histology. These results suggest that a single 500$\mu$g-delivery of pCK-VEGF is potent enough to induce sufficient angiogenic activity and achieve therapeutic benefit on this rabbit model.

• Journal of the Institute of Convergence Signal Processing
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• v.5 no.2
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• pp.96-105
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• 2004

The recovering 3D image from 2D requires the depth information for each picture element. The manual creation of those 3D models is time consuming and expensive. The goal in this paper is to estimate the relative depth information of every region from single view image with camera translation. The paper is based on the fact that the motion of every point within image which taken from camera translation depends on the depth. Motion vector using full-search motion estimation is compensated for camera rotation and zooming. We have developed a framework that estimates the average frame depth by analyzing motion vector and then calculates relative depth of region to average frame depth. Simulation results show that the depth of region belongs to a near or far object is consistent accord with relative depth that man recognizes.

• Journal of Institute of Convergence Technology
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• v.1 no.1
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• pp.34-40
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• 2011

In this paper, a hybrid design tool combining one-dimensional(1D) lumped model and three-dimensional computational fluid dynamics(CFD) approach has been developed in order to evaluate the performance of inkjet print head and droplet control process are studied to reduce the deviations between nozzles which affect the size of the printed line for the industrial application of direct writing on printed circuit boards(PCB). 1D lumped model analysis shows that it is useful tool for evaluating performance of an inkjet head by varying the design parameters. The differences in ejected volume and droplet velocity between analytical and experimental result are within 12%. Time sequence of droplet generation is verified by the comparison between 3D analysis result and photographic images acquired by stroboscopic technique. In addition, by applying DPN process, velocity and volume uniformity between nozzles is dramatically improved that the tolerance achieved by the piezoelectric inkjet printhead across the 64 nozzles is 5 to 8%. A printed line pattern is successfully obtained using the fabricated inkjet print head and droplet calibration system.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.33 no.1
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• pp.73-79
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• 2001

Stricter environmental demands have increased the need to replace conventional C/D bleaching sequence by chlorine-free sequence. Permanganate is well known as a powerful oxidant and have been used industrially in variable fields. However, it has considered to be difficult to use permanganate as a bleaching reagent because of its strong oxidative effect decreasing the viscosity of pulps extremely. We have tried to use permanganate as a bleaching reagent for KP under the mild condition and it was clear that pernanganate oxidized lignin remained in pulps selectively and increased pulp brightness decreasing K number of pulps with small degradation of cellulose. We have employed the neutral condition in the permanganate bleaching process in this study. In this case, permanganate was converted to manganese dioxide after bleaching reaction. The manganese dioxide is remained in the treated pulp fibers because of its insolublity in water. So it was required to reduction the manganese oxide to manganese ion by using reductants with acid. In this paper, we proposed to use oxalic acid as a reducing reagent converting manganese oxide to manganese ion after bleaching reaction. Oxalic acid plays the role as a reductant and a acid, so post-treatment after bleaching became to be easy by using oxalic acid. On the study using lignin model compounds, it was clear that permaganate react with phenols firstly, after that oxalic acid reduce the manganese oxide to manganese ion in the mixture of permanganate, phenols and oxalic acid. Several lignin model compounds ($\textit{p}$-hydroxybenzaldehyde, vanillin, syringaldehyde, veratraldehyde) are selected to elucidate the effect of substituents on reaction rate and its mechanism with permanganate including oxalic acid in this study. Except for veratraldehyde, the rate of oxidative degradation of phenolic compounds by permanganate with oxalic acid are higher than neutral condition. Especially, the degradation rate of $\textit{p}$-hydroxybenzaldehyde are strongly dependent on pH of reaction mixture. On the other hand, the degradation rate of veratraldehyde are decreased with decreasing pH and main degradation product is veratric acid. This result indicate that pH of bleaching liquor should be kept over 2 to degrade of non-phenolic lignin in the pulps effectively in permanganate bleaching.

• Journal of the Korea Society of Computer and Information
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• v.17 no.5
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• pp.1-7
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• 2012

In this paper, we design and implement the simulator for WAN storage replication model performance evaluation in cloud computing environment. Each cloud of simulator is composed of virtual machine emulator and storage emulator. The virtual machine emulator is composed of read/write ratio module, the read/write sequence combination module, and the read/write request module. The storage emulator is composed of storage management module, data transfer module, read/write operations module, and overhead processing module. Using the simulator, we evaluate performance of migration scheme, pre-copy and the post-copy, considering about read/write ratio, network delay, and network bandwidth. Through simulation, we have confirmed that the average migration time of pre-copy was decreased proportional to the read operation. However, average migration time of post-copy was on the increase. Also, the average migration time of post-copy was increased proportional to the network delay. However, average migration time of pre-copy was shown uniformly. Therefore, we show that pre-copy model more effective to reduce the average migration time than the post-copy model. The average migration time of pre-copy and post-copy were not affected by the change of network bandwidth. Therefore, these results show that selects the storage replication model to be, the network bandwidth know not being the important element.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.32 no.10
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• pp.53-59
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• 2004

A calibration technique for a redundant IMU with low-grade inertial sensors is proposed. In order to calibrate the redundant IMU that can detect and isolate a faulty sensor, the fundamental coordinate frames in the IMU are defined and the IMU error is modeled based on the frames. Equations to estimate the error coefficients of the redundant IMU are formulated, and a test sequence using the 2-axis rate table is also presented. Finally, a redundant IMU with cone configuration is implemented using the low-grade inertial sensors and the performance of the proposed technique is verified by some experiments.

• Journal of KIISE:Software and Applications
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• v.31 no.11
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• pp.1474-1482
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• 2004

In this paper, we propose an approach for extracting and filtering block motion vectors using an adaptive weight function. We first extract motion vectors from a sequence of images by using size-varibale block matching and then process them by adaptive robust estimation to filter out outliers (motion vectors out of concern). The proposed adaptive robust estimation defines a continuous sigmoid weight function. It then adaptively tunes the sigmoid function to its hard-limit as the residual errors between the model and input data are decreased, so that we can effectively separate non-outliers (motion vectors of concern) from outliers with the finally tuned hard-limit of the weight function. The experimental results show that the suggested approach is very effective in filtering block motion vectors.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.24 no.9A
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• pp.1383-1391
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• 1999

This paper presents a rate control method that minimizes global distortion under given target bit rates for video communication. This method makes the quality of reconstructed images better than that of the conventional ones based on R-D model at the same bit rates. Given a set of quantizers, a sequence of macroblocks to be quantized selects the optimal quantizer for each macroblock so that the total cost measure is minimized and the finite buffer is never in overflow. To solve this problem we provide a heuristic algorithm based on Lagrangian optimization using an operational rate-distortion framework and a quantization method follows H.263recommendation.

• Journal of Institute of Control, Robotics and Systems
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• v.14 no.11
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• pp.1174-1179
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• 2008

Many modeling and calibration methods have been developed to analyze and design the biological wastewater treatment process. For the systematic use of activated sludge model (ASM) in a real treatment process, a most important step in this usage is a calibration which can find a key parameter set of ASM, which depends on the microorganism communities and the process conditions of the plants. In this paper, a standardized calibration protocol of the ASM model is developed. First, a weighted effluent quality index(WEQI) is suggested far a calibration protocol. Second, the most sensitive parameter set is determined by a sensitive analysis based on WEQI and then a parameter optimization method are used for a systematic calibration of key parameters. The proposed method is applied to a calibration problems of the single carbon removal process. The results of the sensitivity analysis and parameter estimation based on a WEQI shows a quite reasonable parameter set and precisely estimated parameters, which can improve the quality and the efficiency of the modeling and the prediction of ASM model. Moreover, it can be used for a calibration scheme of other biological processes, such as sequence batch reactor, anaerobic digestion process with a dedicated methodology.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.10 no.4
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• pp.145-150
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• 2010

In this paper, we propose additional data transmission system for spectrum efficiency improvement and derive channel capacity formula as a approximated closed-form. Spread spectrum watermarking scheme is selected for the watermarking embedder. Nakagami-q (Hoyt) model is considered as a multipath fading channel. Numerical results show the channel capacity variation of the proposed system in wireless fading channel. From the results, we confirm that the channel capacity of the watermarking system is affected by the fading coefficient and system parameters such that host sampling frequency, host-to-watermark ratio, watermark-to-noise ratio, and PN sequence length.