• 분석과학
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• 제10권6호
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• pp.408-417
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• 1997

기능성 헤테로 고리 화합물의 구조 이성질체를 정상 및 역상 액체 크로마토그래피를 이용하여 분리하고, 이들 분리를 위한 최적 조건을 알코올 변형체(modifier)를 포함한 삼성분 이동상(ternary solvent system)을 이용하여 조사했다. 삼성분 이동상의 경우 알코올 변형체가 컬럼의 활성 표면에 우선적으로 상호작용하여 비활성화(deactivation)시킴으로써 용질의 머무름을 감소시키고 꼬리 끌림(tailing)을 억제하여 분리선택성이 좋아지는 것으로 보인다. 구조 이성질체 분리의 경우 정상 액체 크로마토그래피를 이용할 경우가 분리 선택성이 더 좋은 것으로 나타났다. 또한, 헤테로 고리 화합물들의 머무름 거동은 역상 액체 크로마토그래피의 경우는 시료와 정지상과의 소수성 상호작용등으로 설명할 수 있었고, 정상 액체 크로마토그래피의 경우는 시료 분자와 충진제의 흡착표면과의 흡착력으로 설명할 수 있었다.

• 천문학회지
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• 제29권2호
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• pp.119-136
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• 1996

To examine the effect of neighboring galaxies on the gravitational lensing statistics, we performed numerical simulations of lensing by many galaxies. The models consist of a galaxy in the rich cluster like Coma, or a galaxy surrounded by field galaxies in $\Omega_0 = 1$ universe with $\Omega_{gal} = 0.1,\;\Omega_{gal} = 0.3\;or\;\Omega_{gal}=1.0\;,\;where\;\Omega_{gal}$ is the total mass in galaxies. Field galaxies either have the same mass or follow Schechter luminosity function and luminosity-velocity relation. Each lensing galaxy is assumed to be singular isothermal sphere (SIS) with finite cutoff radius. In most simulations, the lensing is mainly due to the single galaxy. But in $\Omega_{gal} = 3$ universe, one out of five simulations have 'collective lensing' event in which more than two galaxies collectively produce multiple images. These cases cannot be incorporated into the simple 'standard' lensing statistics calculations. In cases where 'collective lensing' does not occur, distribution of image separation changes from delta function to bimodal distribution due to shear induced by the surrounding galaxies. The amount of spread in the distribution is from a few $\%\;up\;to\;50\%$ of the mean image separation in case when the galaxy is in the Coma-like cluster or when the galaxy is in the field with $\Omega_{gal} = 0.1\;or\;\Omega_{gal}=0.3.$ The mean of the image separation changes less than $5\%$ compared with a single lens case. Cross section for multiple image lensing turns out to be relatively insensitive to the presence of the neighboring galaxies, changing less than $5\%$ for Coma-like cluster and $\Omega_{gal}=0.1,\;0.3$ universe cases. So we conclude that Coma-like cluster or field galaxies whose total mass density $\Omega_{gal}<0.3$ do not significantly affect the probability of multiple image lensing if we exclude the 'collective lensing' cases. However, the distribution of the image separations can be significantly affected especially if the 'collective lensing' cases are included. Therefore, the effects of surrounding galaxies may not be negligible when statistics of lensing is used to deduce the cosmological informations.

• 한국통신학회논문지
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• 제14권1호
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• pp.75-83
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• 1989

본 논문에서는 복사면 가장자리가 결합된 두 구형 마이크로스트립안테나에, 패치 사이의 복사면 가장자리의 결합을 특성화하는 REC 모델을 적용하여 여러가지 결합간격에 대해 산란계수 $\mid$ $S_{11}$ $\mid$과 $\mid$ $S_{12}$ $\mid$를 구하였으며, 이를 실험치와 비교하였다. 그리고 복사면 가장자리에서의 결합을 이용한 기생소자를 갖는 구형 마이크로스트립 안테나에, REC 모델을 적용하여 궤환 손실을 구한 뒤 실험치와 비교하였다. 여기서 각각의 안테나는 50$\Omega$ 마이크로스트립 선로에 의해 급전한 결과를 다루었으며, 이는 REC 모델을 이론적으로 제시하여 동축선로로 급전한 결과$^{(10)}$와 비교하기 위한 논문이다.

• 한국광물학회지
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• 제18권3호
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• pp.155-164
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• 2005

무등산지역에서 산출되는 화산암은 화순안산암, 무등산데사이트, 도곡유문암으로 구성되며 이들 화산암류는 공통적으로 사장석 반정을 포함하고 있다. 광학현미경 하에서 관찰된 사장석의 반복 쌍정 중 대부분은 알바이트 쌍정이며 일부가 페리클라인 쌍정을 보인다. 사장석들은 EPMA 분석 결과 화순안산암은 Ca 함량이 많은 안데신에, 무등산데사이트는 안데신에서 을리고클레이스에, 그리고 도곡유문암은 거의 순수한 알바이트에 해당한다. 광학현미경 하에서 판단이 어려운 알바이트와 페리클라인 쌍정은 전자현미경의 회절도형에서 쉽게 구분할 수 있다. 연구지역의 화산암에서 산출되는 사장석은 중간조성의 사장석이지만 빠른 냉각속도에 의해 생성되었기 때문에 상분리가 일어나지 않아[100] 방향의 전자회절도형에서 e-reflection이 나타나지 않는 것으로 사료된다.

• Journal of Microbiology and Biotechnology
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• 제30권11호
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• pp.1769-1776
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• 2020

As part of our current work to discover structurally and/or biologically novel compounds from Korean wild mushrooms, we isolated five ergostane-type steroids (1-5) from the fruiting bodies of Xerula furfuracea via repeated column chromatographic separations and HPLC purification. The chemical structures of the isolated steroids were shown to be (22E,24R)-24-methylcholesta-4,22-diene-3,6-dione (1), ergosta-7,22-diene-3β,5α,6β-triol (2), ergosta-7,22-diene-3β,5α,6β,9α-tetraol (3), (22E,24R)-5α,8α-epidioxyergosta-6,22-diene-3β-ol-3-O-β-D-glucopyranoside (4), and (22E,24R)-5α,8α-epidioxyergosta-6,9,22-triene-3β-ol-3-O-β-D-glucopyranoside (5)based on comparison of the data regarding their spectroscopic and physical properties with those of previous studies. Notably, this is the first report on the presence of the identified steroids (1-5) in this mushroom. We tested compounds 1-5 to determine their effects on adipogenesis and osteogenesis in the mouse mesenchymal stem cell line C3H10T1/2 and found that compounds 4 and 5 suppressed the differentiation of stem cells into adipocytes. Notably, in addition to its suppressive effect on adipogenesis, compound 5 was also shown to promote the osteogenic differentiation of stem cells. These findings demonstrate that the bioactive compounds isolated might be effective for the treatment of menopause-associated syndromes, such as osteoporosis and obesity, as the isolated compounds were shown to suppress adipogenesis and/or promote osteogenesis of stem cells.

• 한국응용과학기술학회지
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• 제21권4호
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• pp.345-351
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• 2004

Highly ordered pure-silica MCM-41 materials possessing well-defined morphology have been successfully prepared with surfactant used as a template. The fabrication of mesoporous silica has received considerable attention due to the need to develop more efficient materials' for catalysis, separations, and chemical sensing. The surface modified MCM-41 was used as anadsorbent for biomolecules. Silica-supported organic groups and DNA adsorption on surface modified MCM-41 were investigated by FT-IR and UV-Vis spectrometer, respectively. The use of MCM-41 as the modification of electrode surfaces were investigated electrochemical properties of metal mediators with biomolecules. The modified ITO electrodes increased peak currents for a redox process of $[Ru(bpy)_3]^{2+}$ relative to the bare electrode. The electrochemical detection of DNA by cyclic voltammetry when the current is saturated in the presence of the mediator appeared more sensitive due to a higher catalytic current on the MCM-41 supported electrodes modified by carboxylic acid functional groups. The carboxyl or amine groups on the surface of MCM-41 interact and react with the $-NH_2$ groups of guanine and backbone, respectively. Highly ordered mesoporous materials with organic groups could find applications as DNA sensors.

• 대한치과교정학회지
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• 제21권3호
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• pp.603-614
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• 1991

To study the possibility of attraction magnetic forces to expand maxillary arch, we used 2 big adult dogs, 2 small puppies, 1 small adult dog as experiments, and 1 small adult dog as a control. We measured the intercanine width and intermolar width and histologically observed in the suture and cervical and apex region of teeth and took occlusal X-rays to observe separation of suture line in the maxilla. The results were as follows: 1. Expansion velocities of intercanine (0.25mm/day) and intermolar widths (0.23mm/day) in puppies were faster than those (0.135mm/day, 0.09mm/day) in adults. 2. In all experiments in adults (0.135mm/day) and puppies (0.25mm/day), expansion velocity of intercanine widths were faster than those (0.09mm/day, 0.23mm/day) of intermolar width. 3. In all experiments ectatic changes were observed and cellularities of fibroblast increased in the suture line. Only in adults dogs the separations of palatal suture were observed in the occlusal X-ray view. 4. In the puppies bony deposition was particularly observed in the suture line and micro-bony fragments were often observed. 5. In the all experiments no root resorption was observed in the cervical and root area, but normal root resorption due to eruption of permanent teeth was observed in the puppies.

• Bulletin of the Korean Chemical Society
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• 제26권6호
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• pp.892-898
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• 2005

A long, bis(monodentate), linking Schiff-base ligand L (py-CH=N-$C_6H_4$-N=CH-py) was prepared from 1,4-phenylenediamine and 3-pyridinecarboxaldehyde by the Schiff-base condensation. Ligand L has two terminal pyridyl groups capable of coordinating to metals through their nitrogen atoms. In contrast, the same reaction between 1,2-phenylenediamine and 3-pyridinecarboxaldehyde produced a mixture of imidazol isomers (2-pyridin-3-yl-1H-benzoimidazole), which are connected to one another by the N-H…N hydrogen bonding to form a tetramer. From Zn($NO_3)_2{\cdot}6H_2O$ and ligand L under various conditions, one discrete molecule, trans- [Zn($H_2O)_4L_2]{\cdot}(NO_3)_2{\cdot}(MeOH)_2$, and two 1-D zinc polymers, [Zn$(NO_3)(H_2O)_2(L)]{\cdot}(NO_3){\cdot}(H_2O)_2$ and [Zn(L) (OBC)($H_2O$)], were prepared. In ligand L, the N$\ldots$N separation between the terminal pyridyl groups is 13.994 $\AA$, with their nitrogen atoms at the meta positions (3,3’) in a trans manner. The corresponding N$\ldots$N separations in its compounds range from 13.853 to 14.754 $\AA$.

• Wind and Structures
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• 제20권1호
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• pp.37-58
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• 2015

As wind flows around a sharp-edged body, the resulting separated flow becomes complicated, with multiple separations and reattachments as well as vortex recirculation. This widespread and unpredictable phenomenon has long been studied academically as well as in engineering applications. In this study, the flow characteristics around rectangular prisms with five different aspect ratios were determined through wind tunnel experiments and a detached eddy simulation, that placed the objects in a simulated deep turbulent boundary layer at $Re=4.6{\times}10^4$. A series of rectangular prisms with the same height (h = 80 mm), different longitudinal lengths (l = 0.5h, h, and 2h), or different transverse widths (w = 0.5h, h, and 2h) were employed to observe the effects of the aspect ratio. Furthermore, five wind directions ($0^{\circ}$, $10^{\circ}$, $20^{\circ}$, $30^{\circ}$, and $45^{\circ}$) were selected to observe the effects of the wind direction. The simulated results of the surface pressure were compared to the wind tunnel experiment results and the existing results of previous papers. The vortex and spectrum were also analyzed to determine the detailed flow structure around the body. The paper also highlights the pressure distribution around the rectangular prisms with respect to the different aspect ratios. With an increasing transverse width, the surface suction pressure on the top and side surfaces becomes stronger. In addition, depending on the wind direction, the pressure coefficient experiences a large variation and can even change from a negative to a positive value on the side surface of the cube model.

• Ocean Systems Engineering
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• 제10권1호
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• pp.87-110
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• 2020

Catamaran has recently been a choice to support a typical vertical axis turbine in floating tidal current energy conversion system. However, motion responses associated with the catamaran can reduce the turbines efficiency. The possibility to overcome this problem isto change the catamaran parameter by varying and simulating the demi-hull separations to have lower motion responses. This simulation was undertaken by Computational Fluid Dynamic (CFD) using potential flow analysis. Cases of demi-hull separation were considered, with ratios of demi-hull separation (S) to the breadth of demi-hull (B), ^S/_B of 3.45, 4.95, 6.45, 7.2 and 7.95. In order to compare to the previous works in the literature, the regular wave was set with wave height of 0.8 m. Furthermore, the analysis was carried out by irregular waves with significant wave height, H_s, of about 0.09 to 1.5 m and the wave period, T, of about 1.5 to 6 s or corresponding to the wave frequency, ω, of about 1.1 to 4.2 rad/s. The wave spectrum was derived from the equation of the International Towing Tank Conference (ITTC). For the case of turbines-loaded catamaran under consideration, the new finding is that the least significant amplitude response can be satisfied at the ratio ^S/_B of 7.2. This study indicates that selecting a right choice of demi-hull separation ratio could contribute in reducing motion responses of the tidal current turbines-loaded catamaran.