• Title/Summary/Keyword: senstivity

Search Result 17, Processing Time 0.024 seconds

The senstivity characteristics of cholesterol sensor by immobilization methods of the enzyme (효소 고정화 방법에 따른 콜레스테롤 센서의 감도 특성)

  • Song, Min-Jung;Yoon, Dong-Hwa;Jin, Joon-Hyung;Min, Nam-Ki;Hong, Suk-In
    • Proceedings of the KIEE Conference
    • /
    • 2003.07c
    • /
    • pp.1935-1937
    • /
    • 2003
  • 최근 콜레스테롤 센서는 전극 상에 효소를 고정화 하는 방식을 이용하여 센서의 집적도를 높이는 시도가 이루어지고 있다. 이러한 전극 상의 효소고정화 방식으로 entrapment, cross liking, covalently binding 등이 있다. 본 논문에서는 이러한 효소 고정화 방식-전도성 고분자인 P3MT를 사용하여 entrap시키는 방법과 silanization을 이용한 covalent bonding 시키는 방법-에 따른 전기화학 센서의 감도 특성에 관한 연구를 수행하였다. 전도성 고분자를 사용한 고정화 방법은 cyclic voltammograms으로 scan rate 10 mA/s, potential 0.5-1.3V의 조건하에서 P3MT를 Polymerization하고, 효소 고정화를 위해 chromoampermeter로 potential 0.6V에서 900초 동안 수행하였다. silanization을 이용한 covalent bonding 시키는 방법은 nitric acid로 Pt 전극표면을 산화시키고, APTER로 silanization 공정을 시행하였다. 효소 고정화를 위해 전해질로는 0.1M Phosphate buffer solution을 사용하여 cyclic voltammograms으로 scan rate 50 mA/s 전위 0.0-0.7V의 조건 하에서 수행하였다. 이 결과 전도성 고분자를 이용한 고정화 방법에서의 senstivity가 0.89 ${\mu}A/mM{\cdot}cm^2$이고, silanization을 이용한 효소 고정화 방법에서는 1.51 ${\mu}A/mM{\cdot}cm^2$였다. 이처럼 후자의 방법에서 더 좋은 감도 특성이 나타났다. 따라서, silanization을 이용한 고정화 방법이 센서 제작 방식으로 더 적합하다고 사료된다.

  • PDF

Senstivity analysis according to the geometric change of the stress-concentrated part of round bar with step (단이 있는 환봉에서 응력집중 부위의 형상 변화에 따른 민감도 해석)

  • Hwang, Suk-Hwan;Kim, Jin-Hwan;Jung, Jin-Han
    • Proceedings of the KSME Conference
    • /
    • 2000.04a
    • /
    • pp.854-859
    • /
    • 2000
  • When the round bar with step is twisted and bent, stress concentration is occurred in the irregular geometric parts. Two dimensional axisymmetric stress analysis is carried out according to the geometric change of the stress-concentrated part of round bar with step. Three dimensional cases are also investigated.

  • PDF

Finite Element Model Updating of Framed Structures Using Constrained Optimization (구속조건을 가진 최적화기법을 이용한 골조구조물의 유한요소모델 개선기법)

  • Yu, Eun-Jong;Kim, Ho-Geun
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 2007.11a
    • /
    • pp.446-451
    • /
    • 2007
  • An Improved finite element model updating method to address the numerical difficulty associated with ill-conditioning and rank-deficiency. These difficulties frequently occur in model updating problems, when the identification of a larger number of physical parameters is attempted than that warranted by the information content of the experimental data. Based on the standard Bounded Variables Least-squares (BVLS) method, which incorporates the usual upper/lower-bound constraints, the proposed method is equipped with new constraints based on the correlation coefficients between the sensitivity vectors of updating parameters. The effectiveness of the proposed method is investigated through the numerical simulation of a simple framed structure by comparing the results of the proposed method with those obtained via pure BVLS and the regularization method. The comparison indicated that the proposed method and the regularization method yield approximate solutions with similar accuracy.

  • PDF

Effect of Di-(2-ethyl hexyl) Phthalate on Immune Response in Mice (Di-(2-ethyl hexyl) phthalate가 mouse의 면역 반응에 미치는 영향)

  • 임수한;홍사욱;안영근;정규혁
    • Environmental Analysis Health and Toxicology
    • /
    • v.4 no.1_2
    • /
    • pp.67-73
    • /
    • 1989
  • Recently pathotoxicological study of lymphoid organs by administration of some phthalate ester in rats, indicated marked effect of architechure of thymus, spleen, and lymphonodes. Dioctyl phthalate (DOP), one of the phthalate ester, caused statistically significant reduction in the weights of various lymphoid organs. This senstivity of the lymphoid organ to phthalate toxicity which could lead to adverse effects on the immune response and also suppression of immune system. Therfore it is possible the presense of di-(2-ethylhexyl) phthalate (DEHP), one of the phthalate ester as well as DOP, in spleen and other organs might have some moderately effect on the function of the immune system, So our present study was proceeded to assess the effect of DEHP on the immunotoxicity in mouse. In the immune response of DEHP administered mice, HA, HY, Arthus reaction and Rosette forming cell were decreased but DTH was increased. Furthermore, in the DEHP plus ethanol group, HA, HY, Arthus reaction and Rosette forming cell were remarkably decreased and elevation of DTH was inhibited.

  • PDF

Fabrication and Characterization of DBR Porous Silicon Chip for the Detection of Chemical Nerve Agents

  • Jung, Kyoungsun
    • Journal of Integrative Natural Science
    • /
    • v.3 no.4
    • /
    • pp.237-240
    • /
    • 2010
  • Recently, number of studies for porous silicon have been investigated by many researchers. Multistructured porous silicon (PSi), distributed Bragg reflector (DBR) PSi, has been a topic of interest, because of its unique optical properties. DBR PSi were prepared by an electrochemical etch of $P^{{+}{+}}$-type silicon wafer of resistivity between 0.1 $m{\Omega}cm$ with square wave current density, resulting two different refractive indices. In this work, We have fabricated a simple and portable organic vapor-sensing device based on DBR porous silicon and investigated the optical characteristics of DBR porous silicon. DBR porous silicon have been characterized by FT-IR, Ocean optics 2000 spectrometer. The device used DBR PSi chip has been demonstrated as an excellent gas sensor, showing a great senstivity to a toxic vapor (TEP, DMMP, DEEP) at room temperature.

Senstivity analysis by seismograph of composition Dam (복합댐의 지진계수별 민감도 분석)

  • Kim, Jae-Hong;Oh, Byung-Hyun;Hong, Won-Pho;Jeon, Je-Sung
    • Proceedings of the Korean Geotechical Society Conference
    • /
    • 2008.10a
    • /
    • pp.820-826
    • /
    • 2008
  • Differ number of seismograph to the composition dam by recently frequent earthquake and analyzed responsiveness. Interest for dam inner place by increase of something wrong flood and inside and outside of the country earthquake appearance according to unusual change of weather is risen, on important urea in dam safety floodgate school register by structural safety divide can. Therefore, by PMP (PMF) of dam and increase of domestic earthquake occurrence, need research about earthquake resistant nature ability estimation of water resources facilities. Because responsiveness analysis applies number 0.154 ~ 0.25 g of seismograph, seismic wave that use in analysis is being suitable in dynamic analysis of construction such as Rockfill dam from representative chapter cycle faction and recommend in domestic internal examination design workbook, and use results applied much Hachinohe wave onions in van abroad.

  • PDF

Detection of Voletile Organic Compounds by Using DBR Porous Silicon (DBR 다공성 실리콘을 이용한 휘발성 유기화합물의 감지)

  • Park, Cheol Young
    • Journal of Integrative Natural Science
    • /
    • v.2 no.4
    • /
    • pp.275-279
    • /
    • 2009
  • Recently, number of studies for porous silicon (PSi) have been investigated by many researchers. Multistructured porous silicon such as a distributed Bragg reflector (DBR) PSi, has been a topic of interest, because of its unique optical properties. DBR PSi were prepared by using an electrochemical etch of $P{^+}{^+}$-type silicon wafer with resistivity between 0.1 and $10m{\Omega}cm$. The electrochemical etch with square wave current density results in two different refractive indices in the porous layer. In this work, DBR porous silicon chips for a simple and portable organic vapor-sensing device have fabricated. The optical characteristics of DBR PSi have been investigated. DBR porous silicon have been characterized by FT-IR and Ocean optics 2000 spectrometer. The device used DBR PSi chip has been demonstrated as an excellent gas sensor, showing a great senstivity to organic vapor at room temperature.

  • PDF

Action Characteristics of EK3143 and EK3150, New Cyclohexanedione Herbicides, and Their Effects on Acetyl CoA Carboxylase Activity (신규 cyclohexanedione계 화합물 EK3143과 EK3150의 제초작용 발현특성과 Acetyl CoA Carboxylase 활성에 미치는 효과)

  • Kim, J.S.;Song, J.H.;Cho, K.Y.
    • Korean Journal of Weed Science
    • /
    • v.18 no.4
    • /
    • pp.314-324
    • /
    • 1998
  • This study was carried out to investigate the herbicidal action characteristics of EK3143 and EK3150, newly synthesized cyclohexanedione analogues, and their inhibitory effects on the acetyl-CoA carboxylase activity isolated from various plants. Sethoxydim, a typical cyclohexanedione herbicide, had a high herbicidal activity against only grasses with growth inhibition, leaf chlorosis and necrosis. EK3143 and EK3150 had a lower effect against grasses but a higher effect against broadleaf plants such as black nightshade and velvetleaf than sethoxydim had. Low rate application of EK3143 induced leaf bleaching(whitening), while high rate application induced the same symptoms as those of sethoxydim. EK3150 induced more significant whitening, additionally accompanying a curling of meristem part in broadleaf plants. A consistant tendency was observed between the growth inhibition against grasses and the senstivity of grass ACCase to these compounds, but not between herbicidal activities against broadleaf plants and the senstivity of dicotyledonous ACCase; i.e. EK3150, which had higher herbicidal activity against black nightshade and velvetleaf than EK3143 had in greenhouse, rather showed lower ACCase inhibition. In EK3150-treated barnyardgrass, growth inhibition occurred prior to decrease of photosynthetic pigments, in contrast to that of norflurazon and EK3140. These results suggest that EK3143 and EK3150 may have two target sites, ACCase and an unknown site on fatty acid synthesis related to growth inhibition and bleaching respectively, and their symptoms would be appeared in different degree by a differential binding affinity between two action sites.

  • PDF

An Analysis of the Economic Sensitivity of Imported Fishery Products (수입수산물의 경제적 민감도분석에 관한 연구)

  • Park, Cheol-Hyung;Jang, Young-Soo
    • Journal of Fisheries and Marine Sciences Education
    • /
    • v.20 no.1
    • /
    • pp.78-89
    • /
    • 2008
  • This study is intended to analyse the economic sensitivity of imported fishery products due to decrease in or elimination of tariff rates through the progress of free trade. Forty-seven species of fishes were selected for this study on the basis of the HS Code. The substitution and price effects were calculated using the price elasticities of both domestic and imported demands for fishery products under the assumption of 5% decrease in a tariff rate. Seven main economic variables were extracted from the fishery industry which can mediate the substitution and price effects. A multiple regression analysis was conducted to obtain the influence weights of these main economic variables on both effects. The order of sensitivity of the fishes was calculated using these weights. The 47 fish species were classified into four groups according to their sensitivity based on the means and the standard deviations of their total scores on seven main economic considerations. Nine fish species such as squids, hair tails, shellfishes, and crabs belonged to the hyper-sensitive group, whereas 15 fishes such as eels, sea breams, and sea weeds belonged to the sensitive group. Twelve species including common sea basses, cods, and abalones were among the less-sensitive group, and 11 species including skate rays and mud fishes comprised the non-sensitive group.