• 대한한의학회지
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• 제21권1호
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• pp.29-39
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• 2000

In order to elucidate the toxic mechanism of oxygen radicals in cultured mouse spinal sensory neurons, cytotoxic effect of oxygen radicals was evaluated by M1T assay and NR assay. In addition, protective effect of Sopunghwalhyultang(SPHHT) water extract on oxidant-induced neurotoxicity was investigated on these cultures. Spinal sensory neurons derived from mice were cultured in mediums containing various concentrations of Xanthine Oxidase / Hypoxanthine(XO/HX). Cell viability was measured by MTT assay and NR assay. XO/HX-mediated oxygen radicals remarkably decreased cell viability of cultured spinal sensory neurons in a dose-and time-dependent manner. And also, SPHHT blocked XO/HX-induced neurotoxicity in these cultures. These results suggest that oxygen radicals are toxic and SPHHT are effective in blocking against the oxidant-induced neurotoxicity in cultures of spinal sensory neurons of mice.

• 방송공학회논문지
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• 제25권7호
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• pp.1063-1072
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• 2020

This paper proposes an experimental method for measuring the quality of experience to measure the influence of the participants' immersion, satisfaction, and presence according to the application of sensory effects to 360-degree video. Participants of the experiment watch 360-degree videos using HMD and receive sensory effects using scent diffusing devices and wind devices. Subsequently, a questionnaire was conducted on the degree of immersion, satisfaction, and present feelings for the video you watched. By analyzing the correlation of the survey results, we found that the provision of sensory effects satisfies the 360-degree video viewing, and the experimental method was appropriate. In addition, using the P.910 method, a result was derived that was not suitable for measuring the quality of the immersion and presence of 360-degree video according to the provision of sensory effects.

• Journal of Ginseng Research
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• 제39권3호
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• pp.257-264
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• 2015

Background: Korean Red Ginseng-a steamed root of Panax ginseng Meyer-has long been used as a traditional medicine in Asian countries. Its antipruritic effect was recently found, but no molecular mechanisms were revealed. Thus, the current study focused on determining the underlying molecular mechanism of Korean Red Ginseng extract (RGE) against histamine-induced itch at the peripheral sensory neuronal level. Methods: To examine the antipruritic effect of RGE, we performed in vivo scratching behavior test in mice, as well as in vitro calcium imaging and whole-cell patch clamp experiments to elucidate underlying molecular mechanisms. Results: The results of our in vivo study confirmed that RGE indeed has an antipruritic effect on histamine-induced scratching in mice. In addition, RGE showed a significant inhibitory effect on histamine-induced responses in primary cultures of mouse dorsal root ganglia, suggesting that RGE has a direct inhibitory effect on sensory neuronal level. Results of further experiments showed that RGE inhibits histamine-induced responses on cells expressing both histamine receptor subtype 1 and TRPV1 ion channel, indicating that RGE blocks the histamine receptor type 1/TRPV1 pathway in sensory neurons, which is responsible for histamine-dependent itch sensation. Conclusion: The current study found for the first time that RGE effectively blocks histamine-induced itch in peripheral sensory neurons. We believe that the current results will provide an insight on itch transmission and will be helpful in understanding how RGE exerts its antipruritic effects.

• Journal of Dental Anesthesia and Pain Medicine
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• 제18권6호
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• pp.361-365
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• 2018

Background: Recently, we examined the effects of 2% lidocaine gel on the tactile sensory and pain thresholds of the face, tongue and hands of symptom-free individuals using quantitative sensory testing (QST); its effect was less on the skin of the face and hands than on the tongue. Consequently, instead of 2% lidocaine gel, we examined the effect of 8% lidocaine spray on the tactile sensory and pain thresholds of the skin of the face and hands of healthy volunteers. Methods: Using Semmes-Weinstein monofilaments, QST of the skin of the cheek and palm (thenar skin) was performed in 20 healthy volunteers. In each participant, two topical sprays were applied. On one side, 0.2 mL of 8% lidocaine pump spray was applied, and on the other side, 0.2 mL of saline pump spray was applied as control. In each participant, QST was performed before and 15 min after each application. Pain intensity was measured using a numeric rating scale (NRS). Results: Both the tactile detection threshold and filament-prick pain detection threshold of the cheek and thenar skin increased significantly after lidocaine application. A significant difference between the effect of lidocaine and saline applications was found on the filament-prick pain detection threshold only. NRS of the cheek skin and thenar skin decreased after application of lidocaine, and not after application of saline. Conclusion: The significant effect of applying an 8% lidocaine spray on the sensory and pain thresholds of the skin of the face and hands can be objectively scored using QST.

• 대한통합의학회지
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• 제11권4호
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• pp.237-246
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• 2023

Purpose : This study investigated the effects of personality and sensory processing on college life adaptation in students majoring in occupational therapy. Methods : We conducted a survey study on 251 college students from March to May 2023. Personality, sensory processing, and college life adaptation were measured through the international personality item pool, adolescent/adult sensory profile, and student adaptation to college questionnaire, respectively. The general characteristics of students were analyzed using frequency analysis, and differences in college life adaptation and sensory processing characteristics were analyzed using independent t-tests and one-way ANOVA. The relationship between personality, sensory processing, and college life adaptation scores was analyzed using Pearson correlation analysis. The impact of personality and sensory processing on college life adaptation was analyzed using multivariate regression analysis using SPSS 25.0. Results : Correlations of all five personality factors, except openness to experience, were observed with students' college life adaptation. According to sensory processing characteristics, differences in college life adaption showed significant differences in sensory avoidance, poor registration, and sensory sensitivity. The variance of college life adaptation explained by each factor (based on R²) were 46% by personality and 26% by sensory processing. Among personality traits, neuroticism had a negative effect on college life adaptation, agreeableness and extroversion had positive effects, and low registration during sensory processing had a negative effect. Conclusion : This study suggests the provision of various activities and creation of an environment for college students with low sensory registration and neurotic traits to encourage positive changes. The results can be used to design a program that helps college students adapt to occupational therapy majors.

• 대한감각통합치료학회지
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• 제4권1호
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• pp.17-28
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• 2006

The person's behaviors are interactive with sensory processing ability. So sensory processing ability is very important. Most of tools which evaluate sensory processing are developed for the child. But sensory integrated problems are not restricted to the child. It is possible for sensory integrative problems to happen independent of the intellectual level and the social stratum. And sensory integrative problems are distributed in all age. Adults who have a sensory defensiveness use various coping strategies. But it does not solve a basic sensory defensive problem. Previous studies reported the fact that the sensory integrative treatment has a high treatment effect in these people. In this paper, we present the necessity for adult's sensory processing evaluating tool. We introduces Adolescent/Adult Sensory profile to be translated into Korean. It will discriminate adults who have sensory defensiveness from adult. It will provide these people with the suitable help.

• 대한감각통합치료학회지
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• 제1권1호
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• pp.39-51
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• 2003

Objective : To explore the effect of intensive sensory integration therapy through daily camp programs for children with sensory modulation disorder. Methods : A comparison of quantitative data and qualitative description between before and after sensory integration therapy camp and main outcome measure was used, including MAP behavior checklist, JSI-2, COPM, sensory history, STEP-SI. Results : The adaptive response was increased and sensory modulation problems were observed less than before the camp. Conclusion : For this study a more diverse, extended and intensive SI program is considered necessary. Further study is needed to develop these findings.

• Journal of Animal Science and Technology
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• 제66권2호
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• pp.387-397
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• 2024

Pork quality is determined by several attributes, among which odor and taste are the utmost significant. Therefore, this study was aimed to assess the effects of boar odor hormone concentration on the quality traits and sensory acceptability of pork. A total twenty-six (26) non-castrated 3-way crossbred (Landrace × Yorkshire × Duroc) pigs were selected with an average body weight (ABW) 115.6 kg before to slaughter. The three treatment groups (low, medium and high) were divided according to the androstenone concentration. In experiment 1, for meat quality traits carcass was selected based on androstenone concentration: low (LC, 0.64-0.69 ㎍/g, n = 9), medium (MC, 0.70-0.99 ㎍/g, n = 7) and high (HC, 1.00-1.69 ㎍/g, n = 10). In experiment 2, for sensory evaluation carcasses were also selected based on the abovementioned conditions. Results revealed that androstenone concentration not effect on proximate components, meat quality traits and fatty acids except palmitoleic acid. Sensory evaluation data showed that boar taint and meat boar taint were significantly increased in a concentration-dependent manner from low to high, whereas, gravy and meat flavor preference were significantly increased in LC group than HC group. In addition, correlation analysis showed that boar taint and meat boar taint were positively, and gravy and meat flavor preference were negatively correlated with boar taint hormones. In essence, our findings indicate that androstenone concentration had no effect on meat qualities, but a high concentration of androstenone had a negative effect on the sensory characteristics in uncastrated pigs.

• 한국항행학회논문지
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• 제21권6호
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• pp.666-673
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• 2017

본 논문에서는 MPEG-V 표준 실감미디어 테스트베드에 기반을 둔 문화재 360 콘텐츠 시범서비스 플랫폼을 제안한다. MPEG-V 국제 표준은 바람(wind), 지속광(light), 섬광(flash)와 같은 실감효과메타데이터(SEM; sensory effect metadata) 에 대한 표준 포맷과 장비와의 통신 규약 등을 정의한 것으로, 360VR 콘텐츠와 융합할 경우 체험자로 하여금 실재감(presence)과 몰입감(immersion)의 증대가 가능하다. 제안하는 플랫폼은 문화재 360 콘텐츠를 재현할 수 있도록 특화된 형태로 설계와 구축을 수행하고, 실감효과메타데이터(SEM; sensory effect metadata)와 콘텐츠를 재현시키는 소프트웨어와 하드웨어로 구성되며, 하드웨어는 실감효과 재현 장치로, 소프트웨어는 콘텐츠 플레이어와 실감효과 재현 서버로 구성된다. 제안하는 플랫폼을 활용한 시범서비스 사례와 플랫폼의 특징과 장점에 대해 언급한다.

• The Journal of Asian Finance, Economics and Business
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• 제8권5호
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• pp.939-950
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• 2021

The purpose of this study was to measure the significance and contribution of sensory appeal, lifestyle, and health motive in determining coffee drink consumption. The theory adopted is the SOR (stimulus-organism-response) theory and the AISAS (attention-interest-search-action-share) model approach. Data was collected online in April-May 2020, and obtained 413 valid respondent data. The data were processed using SEM (Structural Equation Modeling) framework. The results showed that the variable sensory appeal of coffee drinks, lifestyle variables and health motive variables had a significant effect on coffee consumption. Of the 13 hypotheses proposed, nine hypotheses are accepted and four hypotheses are rejected. Sensory appeal has a positive effect on attitude and action of coffee consumption. Lifestyle has a positive effect on attitude, search, and action, whereas health motive has a positive effect on attitude of coffee consumption. Lifestyle variables have the greatest role in determining coffee consumption, followed by health motive variables and sensory appeal of coffee drinks. The SOR theory and the AISAS approach can both be used to analyze coffee drinking behavior. The research suggests that, to increase coffee consumption, a marketing approach should touch the lifestyle of the community and increase the promotion of the health aspects of coffee drinks.