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http://dx.doi.org/10.17245/jdapm.2018.18.6.361

Effect of 8% lidocaine spray on the sensory and pain thresholds of the skin of the face and hands evaluated by quantitative sensory testing  

Okayasu, Ichiro (Department of Clinical Physiology, Graduate School of Biomedical Sciences, Nagasaki University)
Komiyama, Osamu (Department of Oral Function and Rehabilitation, Nihon University School of Dentistry at Matsudo)
Ayuse, Takao (Department of Clinical Physiology, Graduate School of Biomedical Sciences, Nagasaki University)
De Laat, Antoon (Department of Oral Health Sciences, KU Leuven)
Publication Information
Journal of Dental Anesthesia and Pain Medicine / v.18, no.6, 2018 , pp. 361-365 More about this Journal
Abstract
Background: Recently, we examined the effects of 2% lidocaine gel on the tactile sensory and pain thresholds of the face, tongue and hands of symptom-free individuals using quantitative sensory testing (QST); its effect was less on the skin of the face and hands than on the tongue. Consequently, instead of 2% lidocaine gel, we examined the effect of 8% lidocaine spray on the tactile sensory and pain thresholds of the skin of the face and hands of healthy volunteers. Methods: Using Semmes-Weinstein monofilaments, QST of the skin of the cheek and palm (thenar skin) was performed in 20 healthy volunteers. In each participant, two topical sprays were applied. On one side, 0.2 mL of 8% lidocaine pump spray was applied, and on the other side, 0.2 mL of saline pump spray was applied as control. In each participant, QST was performed before and 15 min after each application. Pain intensity was measured using a numeric rating scale (NRS). Results: Both the tactile detection threshold and filament-prick pain detection threshold of the cheek and thenar skin increased significantly after lidocaine application. A significant difference between the effect of lidocaine and saline applications was found on the filament-prick pain detection threshold only. NRS of the cheek skin and thenar skin decreased after application of lidocaine, and not after application of saline. Conclusion: The significant effect of applying an 8% lidocaine spray on the sensory and pain thresholds of the skin of the face and hands can be objectively scored using QST.
Keywords
Lidocaine; Neuropathic Pain; Orofacial Pain; Quantitative Sensory Testing;
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