• Analytical Science and Technology
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• v.13 no.3
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• pp.315-322
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• 2000

The response characteristics of the bioelectrode developed by the co-immobilization of spinach root tissue and ferrocene in a carbon paste matrix for the amperometric determination of hydrogen peroxide were evaluated. In the range of electrode potential examined (-0.3~0.0V vs. Ag/AgCl). the response time was relatively short ($t_{95%}=11.8$ sec) and it responded in the wide range of pH. Also, its detection limit was $2.25{\times}10^{-6}M$ (S/N=3) and a relative standard deviation of the measurements which were repeated 15 times using $1.0{\times}10^{-3}M$ hydrogen peroxide was 1.87%. The bioelectrode sensitivity decreased to 40% of the original value in 19 days of continuous use.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.47 no.3
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• pp.302-312
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• 2014

This article describes the design and performance characteristics of a broadband ultrasonic mosaic transducer. We focus on the improved bandwidth in the high frequency band of a previously designed broadband ultrasonic transducer (Lee et al., 2014). The improvement in the pulse-echo bandwidth was achieved by employing twelve $2{\times}2$ element subarrays, operating at different resonance frequencies, and utilizing the mosaic array concept. We found that the -6 dB and -12 dB bandwidths of the newly developed broadband ultrasonic mosaic transducer, were up to 155% and 170% of the previously designed model, with a quality factor of 1.71 and 1.25, respectively. The averaged TVR (transmitting voltage response), SRT (receiving sensitivity), and FOM (figure of merit) values in a nearly flat transmitting response band, from 45 to 105 kHz providing a -12 dB bandwith of 60 kHz, were 163.3 dB (re $1{\mu}Pa/V$ at 1 m), -192.8 dB (re $1V/{\mu}Pa$), and -30.9 dB, respectively.

• Korean Journal of Veterinary Service
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• v.18 no.3
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• pp.13-28
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• 1995

This study was carried out to explore the most sensitive and useful method for simultaneous determination of five sulfa drugs(sulfamethazine, sulfamerazine, sulfamonomethoxine, sulfadimethoxine, sulfaquinoxaline) in livestock productions(pork muscle, bovine muscle, chicken muscle, milk ) by HPLC with UV detector and reverse phase column. The results obtained were as follows：1. For mobile phase acetonitrile-0.01M ammonium acetate (23：77) showed more applicable sensitivity and retention times than acetonitrile-1% acetic acid(23：77). Thus acetonitrile-0.01M ammonium acetate(23：77) selected and applied to the modification test, from which it was found pH 6.75 was the most adequate. 2. Optimal wavelength of UV for SMT(sulfamethazine), SMR(sulfamerazine), SMM(sulfamonomethoxine), SD(sulfadimethoxine), and SQ(sulfaquinoxaline) were 266, 266, 265, 269 and 250nm, respectively, and that for simultaneous application it was 263nm. 3. The average recovery rate by extractant(chloroform, dichloromethane, chlorform+dich-loromethane) in the classic method was not significantly different(p>0.05) but that by chloroform higher than the others. Thus chloroform was found to be adequate as extractant in this classic method. 4. The average recovery rate was 86.5% by the MSPD(matrix solid phase disperse) method, which was significantly higher than that by the classic method(p<0.05). Also the recovery rates by method were significantly different(p<0.05) in accordance with sample and type of drug. The MSPD method was much superior to classic method on clean-up.

• Journal of applied mathematics & informatics
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• v.20 no.1_2
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• pp.35-59
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• 2006

In this paper, we generalized the results of [23, 26], and get the results of the condition number of the W-weighted Drazin-inverse solution of linear system W AW\chi=b, where A is an $m{\times}n$ rank-deficient matrix and the index of A W is $k_1$, the index of W A is $k_2$, b is a real vector of size n in the range of $(WA)^{k_2}$, $\chi$ is a real vector of size m in the range of $(AW)^{k_1}$. Let $\alpha$ and $\beta$ be two positive real numbers, when we consider the weighted Frobenius norm $\|[{\alpha}W\;AW,\;{\beta}b]\|$(equation omitted) on the data we get the formula of condition number of the W-weighted Drazin-inverse solution of linear system. For the normwise condition number, the sensitivity of the relative condition number itself is studied, and the componentwise perturbation is also investigated.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.12
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• pp.1997-2003
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• 2003

Recently, there have been many researches and developments in optical disc drive by high density of track and high access speed. Therefore, the optical pick-up should guarantee highly accurate dynamic characteristics for the wide bandwidth in order to cope with this trend. These demands for optical pick-up actuator can be solved by improvements of lens-holder through the following methods. The first way is the analysis of the sensitivity matrix of design variables for vibration modes after appropriate design parameters are selected like shapes and local dimensions of a lens-holder. The second way is the optimization of design variables by calculating sequential linear programming after the problem of extending bandwidth are converted to problem of minimizing adequate objective function. In the result, modified FE model is obtained through several iterations by finite difference scheme(FDS). While results of the first way show better convergence of the target frequency, the second result shows better reduction of mass increase.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.23 no.4
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• pp.408-412
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• 2014

An electromagnetic launching system presents a viable projectile propulsion alternative with low cost and minimal environmental drawbacks. A coil gun system propels a projectile using an electromagnetic force and the system is mainly employed in military weapon systems and space launch systems. In this paper, we perform optimization design to improve the muzzle velocity by analyzing the sensitivity. The muzzle velocity, which is the most important design function variable, is affected by design variables including the number of axial turns in the electromagnetic coil, number of radial turns in the electromagnetic coil, initial distance between the projectile and the coil, inner radius of the electromagnetic coil, and length of the projectile. An orthogonal arrays matrix is configured, and a finite element analysis is performed utilizing the commercial electromagnetic analysis software MAXWELL. The muzzle velocity of the optimal design is 62.4% greater than that of the initial design.

• Smart Structures and Systems
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• v.8 no.5
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• pp.471-486
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• 2011

Various types of strain sensors have been developed and widely used in the field for monitoring the mechanical deformation of structures. However, conventional strain sensors are not suited for measuring large strains associated with impact damage and local crack propagation. In addition, strain sensors are resistive-type transducers, which mean that the sensors require an external electrical or power source. In this study, a gold nanoparticle (GNP)-based polymer composite is proposed for large strain sensing. Fabrication of the composites relies on a novel and simple in situ GNP reduction technique that is performed directly within the elastomeric poly(dimethyl siloxane) (PDMS) matrix. First, the reducing and stabilizing capacities of PDMS constituents and mixtures are evaluated via visual observation, ultraviolet-visible (UV-Vis) spectroscopy, and transmission electron microscopy. The large strain sensing capacity of the GNP-PDMS thin film is then validated by correlating changes in thin film optical properties (e.g., maximum UV-Vis light absorption) with applied tensile strains. Also, the composite's strain sensing performance (e.g., sensitivity and sensing range) is also characterized with respect to gold chloride concentrations within the PDMS mixture.

• Biomolecules & Therapeutics
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• v.19 no.2
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• pp.149-154
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• 2011

Matrix assisted laser desorption ionization (MALDI) mass spectrometry is commonly used to analyze biological molecules such as proteins, peptides and lipids from cells or tissue. Recently MALDI Imaging mass spectrometry (IMS) has been widely applied for the identification of different drugs and their metabolites in tissue. This special feature has made MALDI-MS a common choice for investigation of the molecular histology of pathological samples as well as an important alternative to other conventional imaging methods. The basic advantages of MALDI-IMS are its simple technique, rapid acquisition, increased sensitivity and most prominently, its capacity for direct tissue analysis without prior sample preparation. Moreover, with ms/ms analysis, it is possible to acquire structural information of known or unknown analytes directly from tissue sections. In recent years, MALDI-IMS has made enormous advances in the pathological field. Indeed, it is now possible to identify various changes in biological components due to disease states directly on tissue as well as to analyze the effect of treated drugs. In this review, we focus on the advantages of MALDI tissue imaging over traditional methods and highlight some motivating findings that are significant in pathological studies.

• Journal of Electrochemical Science and Technology
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• v.9 no.3
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• pp.169-175
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• 2018

Cu-Salen complex was prepared and attached into chitosan (Cs) polymer backbone. Nanocomposite of the synthesized polymer was prepared with functionalized carbon nano-particles (Cs-Cu-sal/C) to modify the electrode surface. The surface morphology of (Cs-Cu-sal/C) nanocomposite film showed a homogeneous distribution of carbon nanoparticles within the polymeric matrix. The cyclic voltammogram of the modified electrode exhibited a redox behavior at -0.1 V vs. Ag/AgCl (3 M KCl) in 0.1 M PB (pH 7) and showed an excellent hydrogen peroxide reduction activity. The Cs-Cu-sal/C electrode displays a linear response from $5{\times}10^{-6}$ to $5{\times}10^{-4}M$, with a correlation coefficient of 0.993 and detection limit of $0.9{\mu}M$ (at S/N = 3). The sensitivity of the electrode was found to be $0.356{\mu}A\;{\mu}M^{-1}\;cm^{-2}$.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2005.11a
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• pp.254-255
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• 2005

In this paper, we investigated electrical characteristics of the X-ray detector of mercuric iodide (HgI2) film fabricated by PIB(Particle-in-Binder) Method on ITO substrates 17cm$\times$20cm in size with thicknesses ranging from approximately 200${\mu}m$ to 240${\mu}m$. In the present study, using I-V measurements, their electrical properties such as leakage current, X-ray sensitivity, and signal-to-noise ratio (SNR),were investigated. The results of our study can be useful in the future design and optimization of direct active-matrix flat-panel detectors (AMFPD) for various digital X-ray imaging modalities.