• Title/Summary/Keyword: sensitivity enhancement

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MRI Enhancement using Perovskite Material for B1 Field Control at 7T (7T MRI에서 B1 필드 조정을 위해 페로브스카이트 재료를 이용한 자기공명영상 향상)

  • Kim, Yong-Tae;Kim, Joo-Yeon;Baek, Hyeon-Man
    • Journal of the Korean Society of Radiology
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    • v.15 no.4
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    • pp.565-573
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    • 2021
  • The spatial distribution of electromagnetic fields in the human body can be adjusted by using high dielectric materials. This method has a complementary compared to other methods. However, it can be used as a powerful dielectric shimming tool in certain applications. It can be manufactured in a geometrically free shape and a pad manufactured according to the purpose can be applied without any change of the system. Especially in ultrahigh magnetic field (UHF) MRI, the clinical high dielectric pad used to increase the intensity of the transmit (B1+) and receive (B1-) fields, which has low sensitivity due to the high operating frequency, has great potential. In addition, there are few studies applied to UHF MRI. Therefore, in this study, a high dielectric material pad made of calcium titanate suspension was developed in the laboratory. And the signal increase of clinically useful images was confirmed in various protocols of UHF 7T MRI.

Vertical root fracture diagnosis in teeth with metallic posts: Impact of metal artifact reduction and sharpening filters

  • Debora Costa Ruiz;Lucas P. Lopes Rosado;Rocharles Cavalcante Fontenele;Amanda Farias-Gomes;Deborah Queiroz Freitas
    • Imaging Science in Dentistry
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    • v.54 no.2
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    • pp.139-145
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    • 2024
  • Purpose: This study examined the influence of a metal artifact reduction (MAR) tool, sharpening filters, and their combination on the diagnosis of vertical root fracture (VRF) in teeth with metallic posts using cone-beam computed tomography (CBCT). Materials and Methods: Twenty single-rooted human premolars - 9 with VRF and 11 without - were individually placed in a human mandible. A metallic post composed of a cobalt-chromium alloy was inserted into the root canal of each tooth. CBCT scans were then acquired under the following parameters: 8 mA, a 5×5 cm field of view, a voxel size of 0.085 mm, 90 kVp, and with MAR either enabled or disabled. Five oral and maxillofacial radiologists independently evaluated the CBCT exams under each MAR mode and across 3 sharpening filter conditions: no filter, Sharpen 1×, and Sharpen 2×. The diagnostic performance was quantified by the area under the receiver operating characteristic curve (AUC), sensitivity, and specificity. These metrics were compared using 2-way analysis of variance with a significance level of α=5%. Intra- and inter-examiner agreement were assessed using the weighted kappa test. Results: Neither MAR nor the application of sharpening filters significantly impacted AUC or specificity (P>0.05). However, sensitivity increased when MAR was combined with Sharpen 1× and Sharpen 2× (P=0.015). The intra-examiner agreement ranged from fair to substantial (0.34-0.66), while the inter-examiner agreement ranged from fair to moderate (0.27-0.41). Conclusion: MAR in conjunction with sharpening filters improved VRF detection; therefore, their combined use is recommended in cases of suspected VRF.

A Review of the Cognitive Neuroscience of Creativity (창의성에 대한 인지신경과학 연구 개관)

  • Cho, Soohyun
    • Korean Journal of Cognitive Science
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    • v.26 no.4
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    • pp.393-433
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    • 2015
  • Creativity refers to the ability to generate novel and useful ideas. Understanding the mechanism of creativity and its enhancement is important in order to solve major problems of the modern society and to improve the wellness of mankind. Creativity is a highly heterogeneous and complex ability which should not be conceptualized as a single entity. Thus, the current literature on creativity is based on a component process approach to creativity. The present study introduces cognitive neuroscience research studying the mechanism of divergent thinking, insight, relational thinking and artistic creativity which are the major components of creativity. Based on an expansive review, the early hypothesis of hemispheric asymmetry emphasizing the importance of the right as opposed to the left hemisphere is not supported by scientific evidence. In addition, there is no consensus or consistency on which specific brain region is related to a certain component of creativity. In fact, there is a mixture of studies reporting involvement of various brain regions across all four lobes of the brain. This inconsistency in the literature most likely reflects heterogeneity of the component processes of creativity and sensitivity of the neural response to differences across tasks and cognitive strategy. The present study introduces examples of representative studies reporting seminal findings on the neural basis and the enhancement of creativity based on innovative methodology. In addition, we discuss limitations of the current cognitive neuroscience approach to creativity and present directions for future research.

Usefulness of Preoperative Breast MRI in Breast Cancer Diagnosed After Excisional Biopsy (유방 절제 생검 후 유방암이 진단된 환자에서 수술 전 자기공명영상의 유용성)

  • Wui, Jung-Hyun;Kang, Bong-Joo;Cha, Eun-Suk;Kim, Sung-Hun;Jung, Na-Young;Choi, Jae-Jeong
    • Investigative Magnetic Resonance Imaging
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    • v.12 no.2
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    • pp.161-169
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    • 2008
  • Purpose : The aim of this study was to evaluate the usefulness of MRI performed after excisional biopsy to diagnose residual cancer and additional lesions. Materials and Methods : A total of 16 patients who had breast cancer diagnosed by excisional biopsy underwent preoperative breast MRI between March 2005 and August 2007 were included. MRI findings were considered positive for residual cancer if focal, thick, or irregular rim enhancement or adjacent enhancing lesion was identified around the postoperative biopsy cavity. And additional lesions separated from biopsy cavity including multifocal, multicentric, or contralateral lesion were evaluated. We evaluated the diagnostic accuracy of MRI, comparing MRI with histopathologic finding, and the impact of MRI on surgical planning. Results : The sensitivity and specificity of MRI for detecting residual disease considering rim enhancement were 85.7%(6/7) and 55.6%(5/9). Additional lesions including multifocal, multicentric, or contralateral lesion were found in 6 patients. In 7 patients, results of MRI findings changed surgical treatment planning. Conclusion : The pattern of rim enhancement on MRI after excisional biopsy is not differential point to evaluate remnant lesion. But MRI has an important role to help the detection of multifocal or multicentric, or contralateral breast malignancies, resulting in beneficial change in surgical treatment planning.

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Quantitative Analysis of Oligosaccharide Structure of Glycoproteins

  • Chang, Kern-Hee;Tamao Endo;Kim, Jung-How
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.5 no.2
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    • pp.136-140
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    • 2000
  • A sensitive and quantiative method for the structural analysis of oligosaccharide was established for the glycoform analysis of glconproproteins. Inthis study, n-linked oligosaccharides of human IgG and bovine transferin were analyzed for the evaluation of the methydrate moiety ofthe method. Chrbohydrate moiety of glycoprotein was relased by hydrazinolysis and purified by paper chromatography. The oligosaccharides were labeled with a fluorescent bye, 2-aminobenzamide, for the enhancement of detection sensitivity. sialylated (acidic) oligosaccharides were separated from neutral oligosaccharide by employing a strong anion-exchange column(MonoQ) followed by the treatment with sialidase. Enzymatically desiayated fractions and neutral fractions of oligosaccharides were applied to normal-phase HPLC to resolve the peaks according to glucose unit (GU). The structure of separated molecules was further determined by sequential digestion with exoglycosidases. As a result, disialylated biantennary complextype oligosaccharide was found to be a major sugar chain in bovine transferrin (63%). In human IgG, core fucosylated asialobiantennary complex oligosaccharides were dominant. These results coincided well with reported results.

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Effects of Dysphagia Treatment Applied to Infants with Pierre Robin Syndrome - Single Subject Research Design

  • Kim, Mikyung;Kim, Deokju
    • International Journal of Advanced Culture Technology
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    • v.8 no.1
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    • pp.1-12
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    • 2020
  • Pierre Robin syndrome is characterized by micrognathia, glossoptosis, and cleft palate. Infants with Pierre Robin syndrome causes feeding difficulty, upper airway obstruction, and other symptoms. This study aims to examine the effects of applying dysphagia treatment to infants with Pierre Robin syndrome. The study participant was an infant who was born four weeks premature and referred for dysphagia treatment approximately 100 days after birth. At the initial assessment, the infant showed oral sensory sensitivity, a high level of facial and masticatory muscle tension, and a low stability of the chin and cheeks with almost no normal "sucking-swallowing-breathing" pattern. We set the baseline period and intervention period using the AB design. During the baseline period, non-nutritive sucking training using a rubber nipple was conducted without implementing an oral stimulation intervention. During the intervention period, non-nutritive sucking training and an oral stimulation intervention were performed. After the intervention period, the infant's daily oral intake and oral intake per time significantly increased compared to that during the baseline period. We observed that the oral intake time of the infant decreased during the intervention period compared to that in the baseline period, which indicated an improvement in control over the chin, tongue, and lip movements, a change in muscular tension, and stabilization of the "sucking-swallowing-breathing" pattern. We provided dysphagia treatment before breastfeeding, it was positive effects such as normal development of the infant, transition from tube feeding to bottle feeding, and enhancement of overall oral motor function.

A Study on Economic Analysis of Digital Archiving (디지털 아카이빙의 경제성 분석 연구)

  • Chung Hye-Kyung
    • Journal of the Korean Society for Library and Information Science
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    • v.38 no.4
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    • pp.251-270
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    • 2004
  • When an institution adopts digital archiving, an economic analysis is required. Though the existing economic analysis considers only tangible benefits, a model to reflect the intangible benefits of digital archiving is needed. This study suggests a comprehensive economic analysis model by applying the value chain concept of information economics. A simulation is conducted on the digital archiving by adopting the concepts of value accelerating and value linking to the economic analysis, and economic factors are derived through sensitivity analysis. The results support the perception that digital archiving contributes to the enhancement of the institution's efficiency.

A Study on Enhanced Accuracy using GPS L1 and Galileo E1 Signal Combined Processing (GPS L1/갈릴레오 E1 복합신호처리를 통한 위치정확도 향상 연구)

  • Sin, Cheon-Sig;Lee, Sang-Uk;Yoon, Dong-Won
    • Journal of Satellite, Information and Communications
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    • v.6 no.1
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    • pp.68-74
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    • 2011
  • In this paper, we present the enhancement results such as availability and accuracy using the GPS L1 and Galileo E1 signal combination. To enhance the acquisition and tracking performance of signal processing in GNSS receiver. several tracking loops with integrator, discriminator, and loop filter module are applied. Also, this paper presents the performance comparison results between prototype receiver equipped with hardware board and software receiver. Also the tracking loop performance of real hardware receiver is verified by comparing with tracking accuracy, sensitivity occurred by the Spirent simulator. Especially, to process the Galileo E1 signal, it is used the a power early late type which is the typical type for DLL discriminator.

A Study on the MDTF for Uncooled Infrared Ray Thermal Image Sensors with High Thermal Coefficient of Resistance (높은 열저항 계수를 가지는 비냉각형 적외선 열영상 이미지 센서용 MDTF(Metal-dielectric Thin Film)에 관한 연구)

  • Jung, Eun-Sik;Jeong, Se-Jin;Kang, Ey-Goo;Sung, Man-Young
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.25 no.5
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    • pp.366-371
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    • 2012
  • In this paper, fabricated by MEMS uncooled micro-bolometer detector for the study in the infrared sensitivity enhancement. Absorption layer SiOx-Metal series MDTF (metal-dielectric thin film) by high absorption rate and has a high thermal coefficient of resistance, low noise characteristics were implemented. Then MDTF were made in a vacuum deposition method. And MDTF for the analysis of the physical properties of silicon wafers were fabricated, TCR (temperature coefficient of resistance) value was made in order to measure the glass wafer and FT-IR (Fourier Transform Infrared spectroscopy) values were made in order to measure the germanium window. The analyzed results of MDTF -3 [%/K] has more characteristics of the TCR. And 8~12 um wavelength region close to 70% in the absorption characteristic.

Bandwidth Enhancement of a Broadband Ultrasonic Mosaic Transducer using 48 Tonpilz Transducer Elements with 12 Resonance Frequencies (12 주파수의 48 tonpilz 진동소자를 이용한 광대역 초음파 모자이크 변환기의 대역폭 확장)

  • Lee, Dae-Jae
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.47 no.3
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    • pp.302-312
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    • 2014
  • This article describes the design and performance characteristics of a broadband ultrasonic mosaic transducer. We focus on the improved bandwidth in the high frequency band of a previously designed broadband ultrasonic transducer (Lee et al., 2014). The improvement in the pulse-echo bandwidth was achieved by employing twelve $2{\times}2$ element subarrays, operating at different resonance frequencies, and utilizing the mosaic array concept. We found that the -6 dB and -12 dB bandwidths of the newly developed broadband ultrasonic mosaic transducer, were up to 155% and 170% of the previously designed model, with a quality factor of 1.71 and 1.25, respectively. The averaged TVR (transmitting voltage response), SRT (receiving sensitivity), and FOM (figure of merit) values in a nearly flat transmitting response band, from 45 to 105 kHz providing a -12 dB bandwith of 60 kHz, were 163.3 dB (re $1{\mu}Pa/V$ at 1 m), -192.8 dB (re $1V/{\mu}Pa$), and -30.9 dB, respectively.