• 제목/요약/키워드: sensitised

검색결과 10건 처리시간 0.028초

THERMAL IGNITION OF A REACTION DIFFUSION SYSTEMS IN SOME CLASS A GEOMETRIES WITH DIFFERENT THERMAL BOUNDARY CONDITIONS

  • Ajadi, S.O.
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • 제11권3호
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    • pp.7-20
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    • 2007
  • We examined the steady state solution for a strongly exothermic mixtures in some class A geometries subjected to different boundary conditions under Arrhenius, Bimolecular and Sensitised reactions. The solution of the governing nonlinear reaction diffusion equation was obtained using the variational method formulation executed in Mathematica package. The paper elucidates the influence of geometry, boundary conditions and types of reaction on the thermal ignition of the reactive mixture. Apart from validating known results in literature, the solution gave further insight into the influence of material properties and conditions on the occurrence of thermal ignition.

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Colloidal Textile Dye-Based Dipstick Immunoassay for the Detection of Infectious Flacherie of Silkworm, Bombyx mori L.

  • Sivaprasad, V.;Nataraju, B.;Renu, S.;Datta, R.K.
    • International Journal of Industrial Entomology and Biomaterials
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    • 제6권1호
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    • pp.27-31
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    • 2003
  • Infectious flacherie of silkworm Bombyx mori is caused by B. mori infectious flacherie virus (BmIFV) and causes severe crop loss to sericulturists. In the present study, a colloidal textile dye-based dipstick immunoassay is developed for the detection of infectious flacherie in silkworms. Colloidal textile dye (blue D2R) with Aλ$_{max}$ at 620 nm was sensitised with 500 $\mu\textrm{g}$/ml of purified anti-BmIFV IgG. The dye-antibody reagent detects purified antigen up to 10 ng/ml and BmIFV infection in diseased larval extracts $(up to a dilution of {10^-5})$ and faecal matter extracts $(up to a dilution of {10^-2})$ by forming clear blue dot within 30 min. It was observed to be stable for three months period at $4^{\circ}C$. The efficacy of textile dye-based dipstick immunoassay was on pay with HRP-based dipstick immunoassay and fluorescent antibody test, and better than latex agglutination and ouchterlony tests in the detection of BmIFV The dye-based dipstick immunoassay method provides a simple, sensitive and less expensive test for the detection of BmIFV infection in silkworms.s.

Cortex Mori Inhibits the CGG-specific IgE-Dependent Histamine Release

  • Chai, Ok-Hee;Kyoung, Jin-Kang;Park, Myoung-Hee-;Lee, Moo-Sam-;Jun, Byoung-Deuk
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 1994년도 춘계학술대회 and 제3회 신약개발 연구발표회
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    • pp.244-244
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    • 1994
  • Cortex Mori, the root bark of mulbery tree has been used as an antiphlogistic, diuretic, and expectorant in herbal medicine. The purpose of this study is to evaluate chicken gamma globulin (CGG)-specific IgE-induced morphologic and functional changes in rat peritoneal mast cells (RPMC), and to determine whether Cortex Mori could inhibit the CGG-specific IgE-depeildent mast cell degranulation and histamine release from RPMC. Results are 1) the degranuration and histamine release from RPMC were not induced within 1 hour after addition of Cortex Mori alone, 2) the CGG and CGG-specific IgE-Induced degranulation from RPMC was observed within 10 minutes, 3) the histamine release from RPMC sensitised with CGG-specific IgE was induced by tile addition of CGG, 4) CGG-specific IgE-dependent degranulation rate in RPMC pretreated with Cortex Mori was significantly Inhibited, compared to that of control group without Cortex Mori pretreatment, and 5) the CGG-specific IgE-dependent histamine release from RPMC was significantly inhibited by pretreatment with Cortex Mori. These data suggest that Cortex Mori contains some substances with capabilities to inhibit CGG-specific IgE-dependent degranulation and histamine release from RPMC.

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통증 생리와 물리치료 원리 (Pain Physiology and Principles of Physical Therapy)

  • 김종만;안덕현
    • 한국전문물리치료학회지
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    • 제5권2호
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    • pp.106-117
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    • 1998
  • The pain is common among individuals with physical disabilities. It can interfere with therapy since patients with pain can become uncooperative and reluctant to move. This paper reviews the natural physiological mechanisms that can reduce pain perception, and considers physiological mechanisms which contribute to clinical pain by describing how the pain system changes its sensitivity depending upon the body's needs. The peripheral and central mechanisms contributing to sensitised nociceptive system are described with reference to the symptoms of clinical pain such as hyperalgesia, allodynia sopntaneous 'on-going'-projected and referred pain. It is suggested that in some chronic pain the nociceptive system maintains a state of sensitivity despite the absence of on-going tissue damage and under such circumstances the nociceptive system itself may have become dysfunctional. Such situations are often initiated by damage to nervous tissue which results in changes in the activity and organization of neuronal circuits within the central nervous system. The ability of the nociceptive system to operate in a suppressed state is also discussed with reference to pain modulation. The physical therapist can help facilitate the activation of these mechanisms through a combination of noninvasive modalities, functional activities, and the therapeutic use of self.

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CNW 하부전극을 사용하여 제조된 염료감응형 태양전지의 특성분석

  • 정용호;김성윤;이상준;최원석;임동건;서영호;최은창;홍병유
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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    • pp.453.2-453.2
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    • 2014
  • 그래핀을 수직으로 성장한 형태인 탄소나노월(Carbon nanowall; CNW)은 탄소를 바탕으로 하는 다른 나노물질에 비해 표면적이 상당히 넓은 물질로 전극에 활용하여 소자 성능향상을 기대 할 수 있다. 또한 탄소를 기반으로 하는 나노 구조물중에서 가장 높은 표면밀도를 가진다. CNW를 차세대 염료감응형 태양전지(Dye sensitised solar cells; DSSC)의 상대전극으로 사용한다면 기존대비 광변환 효율을 향상시킬 수 있어 새로운 상대전극으로 활용 가능하다. 또한 CNW는 다른 촉매 없이 직접성장이 가능함으로 불순물 제거공정이 필요하지 않고, 공정시간이 짧아 대량생산에 용의하다. 본 연구에서는 마이크로웨이브 PECVD 장비를 사용하고 메탄(CH4)을 반응가스로 사용하여 CNW 하부전극을 제조하였다. CNW 하부전극의 광 변환효율을 관찰하기위해서 합성시간을 변화를 주었다. 제조된 DSSC의 광 변환 효율을 측정하기 위해 Solar simulator 장비를 사용하여 제작된 cells의 효율을 측정하였다.

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Selective Catalytic Reduction (SCR) 환경에서 18% 크롬 스테인리스강의 부식 거동 (Corrosion behaviors of 18Cr Stainless Steels in Selective Catalytic Reduction Environments)

  • 김희산
    • Corrosion Science and Technology
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    • 제22권3호
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    • pp.175-186
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    • 2023
  • Effects of high-temperature environment and low-temperature environment on corrosion behaviours of 18Cr stainless steels (type 304L, type 441) in simulated selective catalytic reduction (SCR) environments were studied using weight loss test in each environment and rust analysis. With time to exposure to the high-temperature environment, type 441 was more resistant to corrosion than type 304L due to both higher diffusivity of Cr and lower thermal expansion coefficient in α-iron. The former provides a stable protective Cr2O3 layer. The latter leaded to low residual stress between scale and steel, reducing the spallation of the scale. With time to exposure to the low-temperature environment, on the other hand, type 304L was more resistant to corrosion than type 441. The lower resistance of type 441 was caused by Cr-depleted zone with less than 11% formed during the pre-exposure to a high-temperature environment, unlike type 304L. It was confirmed by results from the crevice corrosion test of sensitised 11Cr steel. Hence, to achieve higher corrosion resistance in simulated SCR environments, ferritic stainless steels having lower thermal expansion coefficient and higher diffusivity of Cr but containing more than 18% Cr are recommended.

Endoplasmic Reticulum Ca2+ Store: Regulation of Ca2+ Release and Reuptake by Intracellular and Extracellular Ca2+ in Pancreatic Acinar Cells

  • Kang, Yun Kyung;Park, Myoung Kyu
    • Molecules and Cells
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    • 제19권2호
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    • pp.268-278
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    • 2005
  • We investigated the effect of cytosolic and extracellular $Ca^{2+}$ on $Ca^{2+}$ signals in pancreatic acinar cells by measuring $Ca^{2+}$ concentration in the cytosol($[Ca^{2+}]_c$) and in the lumen of the ER($[Ca^{2+}]_{Lu}$). To control buffers and dye in the cytosol, a patch-clamp microelectrode was employed. Acetylcholine released $Ca^{2+}$ mainly from the basolateral ER-rich part of the cell. The rate of $Ca^{2+}$ release from the ER was highly sensitive to the buffering of $[Ca^{2+}]_c$ whereas ER $Ca^{2+}$ refilling was enhanced by supplying free $Ca^{2+}$ to the cytosol with $[Ca^{2+}]_c$ clamped at resting levels with a patch pipette containing 10 mM BAPTA and 2 mM $Ca^{2+}$. Elevation of extracellular $Ca^{2+}$ to 10 mM from 1 mM raised resting $[Ca^{2+}]_c$ slightly and often generated $[Ca^{2+}]_c$ oscillations in single or clustered cells. Although pancreatic acinar cells are reported to have extracellular $Ca^{2+}$-sensing receptors linked to phospholipase C that mobilize $Ca^{2+}$ from the ER, exposure of cells to 10 mM $Ca^{2+}$ did not decrease $[Ca^{2+}]_{Lu}$ but rather raised it. From these findings we conclude that 1) ER $Ca^{2+}$ release is strictly regulated by feedback inhibition of $[Ca^{2+}]_c$, 2) ER $Ca^{2+}$ refilling is determined by the rate of $Ca^{2+}$ influx and occurs mainly in the tiny subplasmalemmal spaces, 3) extracellular $Ca^{2+}$-induced $[Ca^{2+}]_c$ oscillations appear to be triggered not by activation of extracellular $Ca^{2+}$-sensing receptors but by the ER sensitised by elevated $[Ca^{2+}]_c$ and $[Ca^{2+}]_{Lu}$.

Computational design of mould sprue for injection moulding thermoplastics

  • Lakkannan, Muralidhar;Mohan Kumar, G.C.;Kadoli, Ravikiran
    • Journal of Computational Design and Engineering
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    • 제3권1호
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    • pp.37-52
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    • 2016
  • To injection mould polymers, designing mould is a key task involving several critical decisions with direct implications to yield quality, productivity and frugality. One prominent decision among them is specifying sprue-bush conduit expansion as it significantly influences overall injection moulding; abstruseness anguish in its design criteria deceives direct determination. Intuitively designers decide it wisely and then exasperate by optimising or manipulating processing parameters. To overwhelm that anomaly this research aims at proposing an ideal design criteria holistically for all polymeric materials also tend as a functional assessment metric towards perfection i.e., criteria to specify sprue conduit size before mould development. Accordingly, a priori analytical criterion was deduced quantitatively as expansion ratio from ubiquitous empirical relationships specifically a.k.a an exclusive expansion angle imperatively configured for injectant properties. Its computational intelligence advantage was leveraged to augment functionality of perfectly injecting into an impression gap, while synchronising both injector capacity and desired moulding features. For comprehensiveness, it was continuously sensitised over infinite scale as an explicit factor dependent on in-situ spatio-temporal injectant state perplexity with discrete slope and altitude for each polymeric character. In which congregant ranges of apparent viscosity and shear thinning index were conceived to characteristically assort most thermoplastics. Thereon results accorded aggressive conduit expansion widening for viscous incrust, while a very aggressive narrowing for shear thinning encrust; among them apparent viscosity had relative dominance. This important rationale would certainly form a priori design basis as well diagnose filling issues causing several defects. Like this the proposed generic design criteria, being simple would immensely benefit mould designers besides serve as an inexpensive preventive cliché to moulders. Its adaption ease to practice manifests a hope of injection moulding extremely alluring polymers. Therefore, we concluded that appreciating injectant's polymeric character to design exclusive sprue bush offers a definite a priori advantage.

Prevalence and Effect of Workplace Violence against Emergency Nurses at a Tertiary Hospital in Kenya: A Cross-Sectional Study

  • Kibunja, Betty Kiunga;Musembi, Horatius Malilu;Kimani, Rachel Wangari;Gatimu, Samwel Maina
    • Safety and Health at Work
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    • 제12권2호
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    • pp.249-254
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    • 2021
  • Introduction: Workplace violence (WPV) is a major occupational and health hazard for nurses. It affects nurses' physical and psychological well-being and impacts health service delivery. We aimed to assess the prevalence and describe the consequences of WPV experienced by nurses working in an emergency department in Kenya. Methods: We conducted a descriptive cross-sectional study among emergency nurses at one of the largest tertiary hospitals in Kenya. We collected data using a structured questionnaire adapted from the 'WPV in the Health Sector, Country Case Studies Research Instruments' questionnaire. We described the prevalence and effects of WPV using frequencies and percentages. Results: Of the 82 participating nurses, 64.6% were female, 57.3% were married and 65.8% were college-educated (65.8%). Participants' mean age was 33.8 years (standard deviation: 6.8 years, range: 23-55). The overall lifetime prevalence of WPV was 81.7% (n = 67, 95% confidence interval [CI]: 71.6%-88.8%) and the 1-year prevalence was 73.2% (n = 63, 95% CI: 66.3-84.8%). The main WPV included verbal abuse, physical violence, and sexual harassment. Most incidents were perpetrated by patients and their relatives. No action was taken in 50% of the incidents, but 57.1% of physical violence incidents were reported to the hospital security and 28.6% to supervisors. Perpetrators of physical violence were verbally warned (42.9%) and reported to the hospital security (28.6%). Conclusion: Workplace violence is a significant problem affecting emergency nurses in Kenya. Hospitals should promote workplace safety with zero-tolerance to violence. Nurses should be sensitised on WPV to mitigate violence and supported when they experience WPV.

TiO2와 Graphene 혼합물을 전극으로 사용한 염료감응형 태양전지특성 연구 (Dye-Sensitized Solar Cell Based on TiO2-Graphene Composite Electrodes)

  • 바트무르;양우승;암바데;이수형
    • Korean Chemical Engineering Research
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    • 제50권1호
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    • pp.177-181
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    • 2012
  • 본 연구에서는 $TiO_2$ 필름에 그라핀나노시트(graphenenanosheet, GNS)의 양을 다르게 함으로써 형성한 전극을 이용하여 염료감응형 태양전지를 제작하였고 그 특성을 연구하였다. $TiO_2$-GNS 혼합물 전극은 단순한 혼합방식에 의하여 제작되었으며, N3를 염료로 사용하여 태양전지의 효율을 평가하였다. $TiO_2$-GNS 혼합물 전극을 사용한 염료감응형 태양전지의 전환효율은 GNS의 양에 의해 영향을 받았으며, $TiO_2$에 GNS를 0.01 wt% 혼합한 전극을 사용하여 제작한 염료감응형 태양전지가 가장 높은 효율인 5.73%를 나타내었다. 이는 GNS를 혼합하지 않은 전극을 사용한 태양전지보다 26% 높은 효율이었다. 이와 같은 효율 증가의 원인으로는 GNS 첨가에 의한 N3의 흡착량 증가, 전자 재결합(electron recombination)과 back transport reaction의 감소, 전자 수송의 증가로부터 기인한 것으로 생각된다. 본 연구에서 $TiO_2$(anatase)와 GNS의 존재는 Field-Emission Scanning Electron Microscopy를 통하여 확인하였으며, 흡착된 염료의 양은 자외선분광기(UV-vis Spectroscopy), 전자 재결합의 감소 및 전자 수송에 대한 분석은 전기화학적 임피던스분광법(Electrochemical Impedance Spectroscopy)을 이용하였다.