• Title/Summary/Keyword: semi-quantitative analysis

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A Study on Implementation of Risk Based Inspection Procedures to a Petrochemical Plant (RBI 절차의 석유화학 플랜트 적용에 관한 연구)

  • Song, Jung-Soo;Shim, Sang-Hoon;Kim, Ji-Yoon;Yoon, Kee-Bong
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.27 no.3
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    • pp.416-423
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    • 2003
  • During the last ten years, the need has been increased for reducing maintenance cost for aged equipments and ensuring safety, efficiency and profitability of petrochemical and refinery plants. RBI (Risk Based Inspection) methodology is one of the most promising technologies satisfying the need in the field of integrity management. In this study, a user-friendly software, realRBl for RBI based on the API 581 code was developed. This software has modules for evaluating qualitative and semi-quantitative risk level, analyzing quantitative risks using the potential consequences of a failure of the pressure boundary, and assessing the likelihood of failure. A quantitative analysis was performed for 16 columns in a domestic NCC (Naphtha Cracking Center) plant whose operating time reaches about 12 years. Each column was considered as two equipment parts by dividing into top and bottom. Generic column failure frequencies were adjusted based on likelihood data. After determining release rate, release duration and release mass for each failure scenario, flammable/explosive and toxic consequences were assessed. Current risks for 32 equipment parts were evaluated and risk based prioritization were determined as a final result.

Quantitative Immunoassay for Polychlorinated Biphenyl Compounds in Electrical Insulating Oils

  • Kim In Soo
    • Proceedings of the Microbiological Society of Korea Conference
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    • 2000.10a
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    • pp.119-127
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    • 2000
  • The development and performance of a competitive indirect immunoassay for the quantitative measurement of polychlorinated biphenyl compounds in insulating oils is presented. Reagent preparation and the assay characterisation, optimisation and validation steps are described. The dynamic range of the assay for Aroclors 1254 and 1260 in methanol was $50-800 {\mu}g\;ml^{-1}$ with $50\%$ signal inhibition values of 217 and $ 212 {\mu}g\;ml^{-1}$ respectively. Impending legislation in the UK is likely to decree that oils containing $ >50 {\mu}g\;ml^{-1}$ PCB be considered contaminated. Assay sensitivity increased with the degree of PCB chlorination. The assay of structurally related compounds of environmental concern yielded cross-reactivity values of under $0.6\%$. The immunoassay proved reliable for the analysis of transformer oils containing $>70{\mu}g\;ml^{-1}$ PCB, but over-estimated PCB levels in oils containing $<20{\mu}g\;ml^{-1}$ of the analyte with the oils requiring pre-treatment using either solid-phase extraction techniques or washing with KOH-ethanol/sulphuric acid to remove matrix interferents. The analytical performance of the assay was compared against a commercially available semi-quantitative immunoassay kit for PCBs in soil and water.

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Corpus-based analysis of the usage of Korean markers -(n)un and -i/ka in editorial texts

  • Kim, Kyoung-Young
    • Language and Information
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    • v.19 no.2
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    • pp.19-36
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    • 2015
  • The aim of this paper is to investigate the usage of Korean markers -(n)un and -i/ka in editorial texts focusing on information structure. Noun phrases ending with the markers -(n)un and -i/ka were annotated semi-automatically using a corpus obtained from an online newspaper. Two important factors to determine the choice of markers were examined with the annotated data: referential givenness/newness and position in a sentence. Referential givenness and newness were adopted as indicators of information structure, topic and focus respectively. In addition to quantitative analysis, qualitative analysis was conducted on the selected data. The results suggest that both the marker -(n)un and -i/ka could carry a topic and a focus reading. Sentence position also played a crucial role in determining the marker, and the marker -i/ka was used more frequently in a later position of a sentence than the marker -(n)un.

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Semi-Quantitative Exposure Assessment of Occupational Exposure to Wood Dust and Nasopharyngeal Cancer Risk

  • Ekpanyaskul, Chatchai;Sangrajrang, Suleeporn;Ekburanawat, Wiwat;Brennan, Paul;Mannetje, Andrea;Thetkathuek, Anamai;Saejiw, Nutjaree;Ruangsuwan, Tassanu;Boffetta, Paolo
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.10
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    • pp.4339-4345
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    • 2015
  • Occupational exposure to wood dust is one cause of nasopharyngeal cancer (NPC); however, assessing this exposure remains problematic. Therefore, the objective of this study was to develop a semi-quantitative exposure assessment method and then utilize it to evaluate the association between occupational exposure to wood dust and the development of NPC. In addition, variations in risk by histology were examined. A case-control study was conducted with 327 newly diagnosed cases of NPC at the National Cancer Institute and regional cancer centers in Thailand with 1:1 controls matched for age, gender and geographical residence. Occupational information was obtained through personal interviews. The potential probability, frequency and intensity of exposure to wood dust were assessed on a job-by-job basis by experienced experts. Analysis was performed by conditional logistic regression and presented in odds ratio (ORs) estimates and 95% confidence intervals (CI). Overall, a non significant relationship between occupational wood dust exposure and NPC risk for all subjects was observed (ORs=1.61, 95%CI 0.99-2.59); however, the risk became significant when analyses focused on types 2 and 3 of NPC (ORs=1.62, 95%CI 1.03-2.74). The significant association was stronger for those exposed to wood dust for > 10 year (ORs=2.26, 95%CI 1.10-4.63), for those with first-time exposure at age > 25 year (ORs=2.07, 95%CI 1.08-3.94), and for those who had a high cumulative exposure (ORs=2.17, 95%CI 1.03-4.58) when compared with those considered unexposed. In conclusion, wood dust is likely to be associated with an increased risk of type 2 or 3 NPC in the Thai population. The results of this study show that semi-quantitative exposure assessment is suitable for occupational exposure assessment in a case control study and complements the information from self-reporting.

Quantitative Analysis on Near Band Edge Images in GaAs Wafer (GaAs 웨이퍼의 대역단 영상에 대한 정량적 해석)

  • Kang, Seong-jun;Na, Cheolhun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.21 no.5
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    • pp.861-868
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    • 2017
  • Near band infrared imaging technique has adopted for imaging EL2 and shallow level distributions in undoped semi-insulating LEC GaAs. This technique, which relies on the mapping of near bandgap infrared transmission, is both rapid and non-destructive. Until now no quantitative analysis has been reported for near band edge region which gives the reverse contrast on EL2 absorption images. This paper presents the spectral, spatial and temperature dependence of photoquenching forward and inverse mechanism in the band edge domain for cells and walls and for direct and inverted contrast conditions during transitory regimes. The difference in the threshold for the EL2w and EL2b defects could be attributed to the contribution of a different electrical assistance due to a different species of impurities. Quantitative analysis results show an increased density of EL2w and a small reduction of EL2b in the region of the walls where there is a high density of dislocations.

Real-time Hybrid Testing a Building Structure Equipped with Full-scale MR dampers and Application of Semi-active Control Algorithms (대형 MR감쇠기가 설치된 건축구조물의 실시간 하이브리드 실험 및 준능동 알고리즘 적용)

  • Park, Eun-Churn;Lee, Sung-Kyung;Lee, Heon-Jae;Moon, Suk-Jun;Jung, Hyung-Jo;Min, Kyung-Won
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.21 no.5
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    • pp.465-474
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    • 2008
  • The real-time hybrid testing method(RT-HYTEM) is a structural testing technique in which the numerical integration of the equation of motion for a numerical substructure and the physical testing for an experimental substructure are performed simultaneously in real-time. This study presents the quantitative evaluation of the seismic performance of a building structure installed with an passive and semi-active MR damper by using RT-HYTEM. The building model that was identified from the force-vibration testing results of a real-scaled 5-story building is used as the numerical substructure, and an MR damper corresponding to an experimental substructure is physically tested by using the universal testing machine(UTM). The RT-HYTEM implemented in this study is validated because the real-time hybrid testing results obtained by application of sinusoidal and earthquake excitations and the corresponding analytical results obtained by using the Bouc-Wen model as the control force of the MR damper respect to input currents were in good agreement. Also for preliminary study, some semi-active control algorithms were applied to the MR damper in order to control the structural responses optimally. Comparing between the test results of semi-active control using RT-HYTEM and numerical analysis results show that the RT-HYTEM is more resonable than numerical analysis to evaluate the performance of semi-active control algorithms.

Application of ELISA for the Detection of Penicillin Antibiotic Residues in Live Animal

  • Lee, H.J.;Lee, M.H.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.11
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    • pp.1604-1608
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    • 2000
  • Penicillin antibiotics such as penicillin G, ampicillin and amoxicillin have been widely used in the pig industry to control salmonellosis, bacterial pneumonia, and urinary tract infections. Extensive use of antibiotics in veterinary clinics has resulted in tissue residues and bacterial resistance. To prevent unwanted drug residues entering the human food chain, extensive control measures have been established by both government authorities and industries. The demands for reliable, simple, sensitive, rapid and low-cost methods for residue analysis of foods are increasing. In this study, we established a rapid prediction test for the detection of pigs with unacceptable tissue residues of penicillins. The recommended therapeutic doses of three penicillins, penillin G (withdrawal time, 7 days), ampicillin (withdrawal time, 7 days) and amoxicillin (withdrawal time, 14 days), were administered to three groups of 20 pigs each. Blood was sampled before drug administration and during the withdrawal period. The concentration of penicillins in plasma, determined by a semi-quantitative ELISA, were compared to that of internal standard, 4 ppb, which corresponded to the Maximum Residue Limit in milk. The absorbance ratio of internal standard to sample (B/Bs) was employed as an index to determine whether drug residues in pig tissues were negative or positive. That is, a B/Bs ratio less than 1 was considered residue positive, and larger than 1 negative. All 60 plasma samples from pigs were negative to three penicillins at pretreatment. Penicillin G could be detected in the plasma of the treated pigs until day 4 post-treatment and ampicillin until day 2, whereas amoxicillin could be detected until day 10 of its withdrawal period. The present study showed that the semi-quantitative ELISA could be easily adapted to detect residues of penicillin antibiotics (penicillin G, ampicillin and amoxicillin) in live pigs.

Application of ELISA for the Detection of Oxytetracycline Residue in Live Animals

  • Lee, H.J.;Lee, M.H.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.12
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    • pp.1775-1778
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    • 2000
  • Oxytetracycline has been widely used in the cattle industry to control pneumonia, shipping fever, foot rot, bacterial enteritis, and uterine infections. Extensive use of antibiotics in veterinary clinics has resulted in residues in tissue and bacterial resistance to antibiotics. To prevent unwanted drug residues from entering the human food chain, extensive control measures have been established by both government authorities and industries. The demands for reliable, simple, sensitive, rapid and low-cost methods for residue analysis of foods are increasing. In this study, we established a rapid test for tissue residues of oxytetracycline in cattle. The recommended therapeutic dose of oxytetracycline (withdrawal time, 14 days) was administered to 10 cattle. Blood samples were collected from each cow before drug administration and during the withdrawal period. The concentration of oxytetracycline in plasma, determined by a semi-quantitative ELISA, was compared to that of the internal standard, 10 ppb. The absorbance ratio of internal standard to sample (B/Bs) was employed as an index to determine whether the residues in cattle tissues were negative or positive. That is, a B/Bs ratio less than 1 was considered as residue positive and that greater than 1 as negative. Based on this criterion, all plasma samples from cattle were negative to oxytetracycline at pre-treatment. Oxytetracycline could be detected in the plasma treated cattle until day 14 post-treatment. The present study showed that the semi-quantitative ELISA could be easily adapted in predicting tissue residues for oxytetracycline in live cattle.

Semi-quantitative Risk Assessment using Bow-tie Method for the Establishment of Safety Management System of Hydrogen Fuel Storage Facility in a Combined Cycle Power Plant (복합화력발전소 내 수소연료 저장설비의 안전관리 체계 구축을 위한 Bow-tie 기법을 활용한 반정량적 위험성 평가)

  • Hee Kyung Park;Si Woo Jung;Yoo Jeong Choi;Min Chul Lee
    • Journal of the Korean Society of Safety
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    • v.39 no.2
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    • pp.75-86
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    • 2024
  • Hydrogen has been selected as one of the key technologies for reducing CO2 emissions to achieve carbon neutrality by 2050. However, hydrogen safety issues should be fully guaranteed before the commercial and widespread utilization of hydrogen. Here, a bow-tie risk assessment is conducted for the hydrogen fuel supply system in a gas turbine power plant, which can be a mass consumption application of hydrogen. The bow-tie program is utilized for a qualitative risk assessment, allowing the analysis of the causes and consequences according to the stages of accidents. This study proposed an advanced bow-tie method, which includes the barrier criticality matrix and visualized maps of quantitative risk reduction. It is based on evaluating the importance of numerous barriers for the extent of their impact. In addition, it emphasizes the prioritization and concentrated management of high-importance barriers. The radar chart of a bow tie allows the visual comparison of risk levels before/after the application of barriers (safety measures). The risk reduction methods are semi-quantitatively analyzed utilizing the criticality matrix and radar chart, and risk factors from multiple aspects are derived. For establishing a secure hydrogen fuel storage system, the improvements suggested by the bow-tie risk assessment results, such as 'Ergonomic equipment design to prevent human error' and 'Emergency shutdown system,' will enhance the safety level. It attempts to contribute to the development and enhancement of an efficient safety management system by suggesting a method of calculating the importance of barriers based on the bow-tie risk assessment.

An Analysis on Signal Control Efficiency in a Three-Leg Intersection Adopting Pedestrian Push-Button System Following Pedestrian volume (3지 교차로에서 보행자 교통량에 따른 보행자작동신호기를 이용한 신호제어효율에 관한 분석)

  • Kim, Eung-Cheol;Cho, Han-Seon;Jung, Dong-Woo;Kim, Hyoung-Soo
    • International Journal of Highway Engineering
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    • v.11 no.3
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    • pp.121-128
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    • 2009
  • This study has proposed the signal operating system to use both semi-actuated signal control and pedestrian push-button as a way to make up for the problems of 3 leg intersections which are operated inefficiently in the signal operation, one of the methods of traffic operations. In case of the semi-actuated signal control, it can reduce delay inside the intersection by serving to uncongested traffic on the main road where there is not much traffic volume on the secondary road and push-button signal can reduce unnecessary waiting time it could happen to vehicles by operating it though there is no pedestrian. Quantitative analysis was tried regarding the average delay reduction per vehicle using VISSIM, microscopic simulation program regarding how much effect it has compared with the existing signal control system and semi-actuated signal control system when the above two advantages are collected. The field test was performed for one three-leg intersection of Incheon. According to respectively signal control method pedestrian traffic changed and executed a sensitivity analysis. The result which compares the average delay time per a vehicle of scenarios, the signal control method of using the pedestrian push-button system in comparison with the fixed signal control method showed to decrease effect of a minimum 3.7 second (10%), a maximum 5.8 second (16%). When the pedestrian traffic volume was 20% or less of the measurement traffic volume, The signal control method of using the pedestrian push-button system appeared to be more efficient the semi-actuated signal control with object intersection.

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