• Asian Pacific Journal of Cancer Prevention
• /
• 제17권7호
• /
• pp.3489-3494
• /
• 2016

Background: A major problem with cervical cancer screening in countries which have no organized national screening program for cervical cancer is sub-optimal participation. Implementation of self-sampling method may increase the coverage. Objective: We determined the agreement of cytological diagnoses made on samples collected by women themselves (self-sampling) versus samples collected by physicians (Physician sampling). Materials and Methods: We invited women volunteers to undergo two procedures; cervical self-sampling using the Evalyn brush and physician sampling using a Cervex brush. The women were shown a video presentation on how to take their own cervical samples before the procedure. The samples taken by physicians were taken as per routine testing (Gold Standard). All samples were subjected to Thin Prep monolayer smears. The diagnoses made were according to the Bethesda classification. The results from these two sampling methods were analysed and compared. Results: A total of 367 women were recruited into the study, ranging from 22 to 65 years age. There was a significant good agreement of the cytological diagnoses made on the samples from the two sampling methods with the Kappa value of 0.568 (p=0.040). Using the cytological smears taken by physicians as the gold standard, the sensitivity of self-sampling was 71.9% (95% CI:70.9-72.8), the specificity was 86.6% (95% CI:85.7-87.5), the positive predictive value was 74.2% (95% CI:73.3-75.1) and the negative predictive value was 85.1% (95% CI: 84.2-86.0). Self-sampling smears (22.9%) allowed detection of micro-organisms better than physicians samples (18.5%). Conclusions: This study shows that samples taken by women themselves (self-sampling) and physicians have good diagnostic agreement. Self-sampling could be the method of choice in countries in which the coverage of women attending clinics for screening for cervical cancer is poor.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권5호
• /
• pp.3029-3035
• /
• 2013

Background: Most developing countries have been unable to implement well-organized health care systems, especially comprehensive Pap smear screening-based programs. One of the reasons for this is regional differences in medical services, and a low-cost portable cervical screening system is necessary. To improve regional discrepancies in cervical screening systems, we investigated the usefulness and acceptability of cervical selfsampling by liquid-based cytology (LBC) for 290 volunteers in the Lao PDR. Materials and Methods: Following health education with comprehensive documents, cervical self-sampling kits by LBC were distributed in three provincial, district, and village areas to a total of 290 volunteers, who were asked to take cytology samples by themselves. Subsequently, the acceptability of self-sampling was evaluated using a questionnaire. Results: The documents were well understood in all three regions. Regarding the acceptability of self-sampling, the selections for subsequent screening were 62% self-sampling, 36% gynecologist-sampling, 1% either method, and 1% other methods. The acceptability rates were higher in the district and the village than in the province. For the relationship between acceptability and pregnancy, the self-sampling selection rate was higher in the pregnancy-experienced group (75%) than in the pregnancy-inexperienced group (60%). For the relationship between selection of self-sampling and experience of screening, the self-sampling selection rate was higher in the screening-inexperienced group (62%) than in the screening-experienced group (52%). Conclusions: Our data show that this new way forward, involving a combination of self-sampling and LBC, is highly acceptable regardless of age, educational background, and residence in rural areas in a developing country.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권18호
• /
• pp.8495-8501
• /
• 2016

Purpose: This study was conducted to assess the agreement and differences between cervical self-sampling with a Kato device (KSSD) and gynecologist sampling for Pap cytology and human papillomavirus DNA (HPV DNA) detection. Materials and Methods: Women underwent self-sampling followed by gynecologist sampling during screening at two primary health clinics. Pap cytology of cervical specimens was evaluated for specimen adequacy, presence of endocervical cells or transformation zone cells and cytological interpretation for cells abnormalities. Cervical specimens were also extracted and tested for HPV DNA detection. Positive HPV smears underwent gene sequencing and HPV genotyping by referring to the online NCBI gene bank. Results were compared between samplings by Kappa agreement and McNemar test. Results: For Pap specimen adequacy, KSSD showed 100% agreement with gynecologist sampling but had only 32.3% agreement for presence of endocervical cells. Both sampling showed 100% agreement with only 1 case detected HSIL favouring CIN2 for cytology result. HPV DNA detection showed 86.2%agreement (K=0.64, 95% CI 0.524-0.756, p=0.001) between samplings. KSSD and gynaecologist sampling identified high risk HPV in 17.3% and 23.9% respectively (p=0.014). Conclusion: The self-sampling using Kato device can serve as a tool in Pap cytology and HPV DNA detection in low resource settings in Malaysia. Self-sampling devices such as KSSD can be used as an alternative technique to gynaecologist sampling for cervical cancer screening among rural populations in Malaysia.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권2호
• /
• pp.559-564
• /
• 2015

Background: The participation of women in cervical cancer screening in Malaysia is low. Self-sampling might be able to overcome this problem. The aim of this study was to assess the reliability of self-sampling for cervical smear in our country. Materials and Methods: This cross-sectional study was conducted on 258 community dwelling women from urban and rural settings who participated in health campaigns. In order to reduce the sampling bias, half of the study population performed the self-sampling prior to the physician sampling while the other half performed the self-sampling after the physician sampling, randomly. Acquired samples were assessed for cytological changes as well as HPV DNA detection. Results: The mean age of the subjects was $40.4{\pm}11.3years$. The prevalence of abnormal cervical changes was 2.7%. High risk and low risk HPV genotypes were found in 4.0% and 2.7% of the subjects, respectively. A substantial agreement was observed between self-sampling and the physician obtained sampling in cytological diagnosis (k=0.62, 95%CI=0.50, 0.74), micro-organism detection (k=0.77, 95%CI=0.66, 0.88) and detection of hormonal status (k=0.75, 95%CI=0.65, 0.85) as well as detection of high risk (k=0.77, 95%CI=0.4, 0.98) and low risk (K=0.77, 95%CI=0.50, 0.92) HPV. Menopausal state was found to be related with 8.39 times more adequate cell specimens for cytology but 0.13 times less adequate cell specimens for virological assessment. Conclusions: This study revealed that self-sampling has a good agreement with physician sampling in detecting HPV genotypes. Self-sampling can serve as a tool in HPV screening while it may be useful in detecting cytological abnormalities in Malaysia.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권20호
• /
• pp.8563-8569
• /
• 2014

Sub-optimal participation is a major problem with cervical cancer screening in developing countries which have no organized national screening program. There are various notable factors such as 'embarrassment', 'discomfort' and 'no time' cited by women as they are often also the bread winners for the family. Implementation of self-sampling methods may increase their participation. The aim of this article was to provide a survey of various types of self-sampling tools which are commonly used in collection of cervical cells. We reviewed currently available self-sampling devices and collated the advantages and disadvantages of each in terms of its acceptance and its accuracy in giving desired results. In general, regardless of which device is used, self-sampling for cervical scrapings is highly acceptable to women in most of the studies cited.

• 한국정보통신학회논문지
• /
• 제15권8호
• /
• pp.1805-1812
• /
• 2011

Bandpass sampling(BPS) 기술은 나이퀴스트(Nyquist) 샘플링 주파수보다 낮은 주파수를 사용하여 RF 대역의 신호를 직접 하향변환 할 수 있다는 장점을 가지고 있지만, 나이퀴스트 영역에서 self-image의 중복을 피하기 위해서는 샘플링 주파수의 선택에 제약이 따른다. 2개의 ADC를 사용하는 2차(second-order) BPS는 self-image를 제거하기 위한 신호처리가 추가 된다는 조건으로 샘플링 주파수의 선택이 자유롭다. 하지만 RF 대역이 바뀌면 신호처리를 위한 파라미타를 재구성해야 한다. 본 논문에서는 2차 BPS의 한 형태인 quadrature BPS의 구조를 가지면서, 재구성이 필요 없는 간단한 보상 필터만을 사용하여 임의 RF 대역으로부터 나이퀴스트 영역으로 하향 변환하는 complex BPS 기반의 SDR front-end에 대하여 기술한다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권17호
• /
• pp.7437-7441
• /
• 2014

Background: Acceptability of self-sampling HPV testing is confirmed worldwide. However, some cultural differences may affect this question. Therefore, this study was conducted to evaluate the acceptability of self-sampling HPV testing in Thai women. Materials and Methods: One hundred women aged 30-65 years with an intact cervix were included in this study. The participants were asked to do the Pap test by physicians and then brush type self-sampling instruments were assigned for self-collection and finally completed a questionnaire for acceptability evaluation. The questionnaire contains 2 parts. Part one covered general information of the participants and part two is the acceptability questions. Results: Mean age was 40.6 years. The incidence of high risk HPV detection in this study was 16%. The most common reason for doing Pap smear was for annual checkup. On the topic of ease of use, 85 % of the subjects agreed. Most of the participants (82%) reported that they felt less pain. However, reliability of the result was not satisfactory because 37% of the participants hesitated to rely on the results of the test. According to the price, if the price is less than 1,000 Baht (32.59 Baht = 1USD), 82% of the subjects would use it for their next screening. Conclusions: The acceptability of self-sampling device in this study is quite good but the reliability of the test was questioned by some of the participants. Moreover, the price of the test in Thailand may also influence the acceptability of the test.

• International journal of advanced smart convergence
• /
• 제10권2호
• /
• pp.194-200
• /
• 2021

The purpose of this study is to analyze the structural relationship among self-leadership, grit, and performance.Specifically, self-leadership was selected as an independent variable, two dimensions of grit were selected as mediator variables, and performance was selected as a dependent variable. This structural equation model is based on previous studies.The subjects of this study were middle and high school Taekwondo players, and the survey was collected using the online survey system KSDC (Korean Social-Science Data Center). The sampling method was a non-probability sampling method, convenience sampling method.A total of 367 copies were collected through this process, and 355 copies were used as the final valid samples after excluding the insincere data.Data processing was done with SPSS 23 for frequency analysis, exploratory factor analysis and reliability analysis. Also, AMOS 21 was used for confirmatory factor analysis and structural equation model analysis. The results of the analysis are as follows: First, self-leadership had a positive effect on bothi interest consistency grit and effort persistence grit. Second, it was found that both interest consistency grit and effort persistence grit have a positive effect on performance.Third,self-leadership had a positive effect on performance.

• Ocean and Polar Research
• /
• 제22권2호
• /
• pp.57-67
• /
• 2000

Time-selective self-triggering water sampler, AUTTLE developed by Jin et al. (1999) has been improved in order to prevent pre-deposition of suspended sediments (SS) before sampling. By using two solenoids, the improved sampler is able to be moored or deployed with inclination. Its position is changed to horizontal position by activating the first solenoid, and then the endcaps of the sampling bottle are closed by the second solenoid that is driven three times to minimize possible failure of sampling. An external control unit for setting sampling time has been also constructed. Additionally, the electric circuit housing of the sampler has been modified to be detached from the sampling bottle when operating manually. Its performance has been confirmed through flume tests and a field experiment. It will serve as a valuable tool in the various fields of oceanography and environmental engineering, especially where seawater sampling synchronized at several sites and/or the information in storm period is important.

• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 1998년도 제13차 학술회의논문집
• /
• pp.244-249
• /
• 1998

In this paper, the hybrid state space self-tuning control technique Is studied within the framework of fuzzy systems and dual-rate sampling control theory. We show that fuzzy modeling techniques can be used to formulate chaotic dynamical systems. Then, we develop the hybrid state space self-tuning fuzzy control techniques with dual-rate sampling for digital control of chaotic systems. An equivalent fast-rate discrete-time state-space model of the continuous-time system is constructed by using fuzzy inference systems. To obtain the continuous-time optimal state feedback gains, the constructed discrete-time fuzzy system is converted into a continuous-time system. The developed optimal continuous-time control law is then convened into an equivalent slow-rate digital control law using the proposed digital redesign method. The proposed technique enables us to systematically and effective]y carry out framework for modeling and control of chaotic systems. The proposed method has been successfully applied for controlling the chaotic trajectories of Chua's circuit.