• Journal of Biomedical Engineering Research
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• v.44 no.3
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• pp.176-181
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• 2023

During cancer treatment, the patient's response to drugs appears differently at the cellular level. In this paper, an image-based cell phenotypic feature quantification and key feature selection method are presented to predict the response of patient-derived cancer cells to a specific drug. In order to analyze the viability characteristics of cancer cells, high-definition microscope images in which cell nuclei are fluorescently stained are used, and individual-level cell analysis is performed. To this end, first, image stitching is performed for analysis of the same environment in units of the well plates, and uneven brightness due to the effects of illumination is adjusted based on the histogram. In order to automatically segment only the cell nucleus region, which is the region of interest, from the improved image, a superpixel-based segmentation technique is applied using the fluorescence expression level and morphological information. After extracting 242 types of features from the image through the segmented cell region information, only the features related to cell viability are selected through the ReliefF algorithm. The proposed method can be applied to cell image-based phenotypic screening to determine a patient's response to a drug.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.784-791
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• 2022

Tack coat is a thin layer of asphalt between the existing pavement and asphalt overlay. During construction, insufficient tack coat layering can later cause surface defects such as slippage, shoving, and rutting. This paper proposed a method for tack coat inspection improvement using an unmanned aerial vehicle (UAV) and deep learning neural network for automatic non-uniform assessment of the applied tack coat area. In this method, the drone-captured images are exploited for assessment using a combination of Mask R-CNN and Grey Level Co-occurrence Matrix (GLCM). Mask R-CNN is utilized to detect the tack coat region and segment the region of interest from the surroundings. GLCM is used to analyze the texture of the segmented region and measure the uniformity and non-uniformity of the tack coat on the existing pavements. The results of the field experiment showed both the intersection over union of Mask R-CNN and the non-uniformity measured by GLCM were promising with respect to their accuracy. The proposed method is automatic and cost-efficient, which would be of value to state Departments of Transportation for better management of their work in pavement construction and rehabilitation.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.8C
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• pp.1159-1174
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• 2004

In this paper, we present an efficient algorithm for region analysis of business card images acquired in a PDA by using DCT and information pixel density. The proposed method consists of three parts: region segmentation, information region classification, and text region classification. In the region segmentation, an input business card image is partitioned into 8 f8 blocks and the blocks are classified into information and background blocks using the normalized DCT energy in their low frequency bands. The input image is then segmented into information and background regions by region labeling on the classified blocks. In the information region classification, each information region is classified into picture region or text region by using a ratio of the DCT energy of horizontal and vertical edge components to that in low frequency band and a density of information pixels, that are black pixels in its binarized region. In the text region classification, each text region is classified into large character region or small character region by using the density of information pixels and an averaged horizontal and vertical run-lengths of information pixels. Experimental results show that the proposed method yields good performance of region segmentation, information region classification, and text region classification for test images of several types of business cards acquired by a PDA under various surrounding conditions. In addition, the error rates of the proposed region segmentation are about 2.2-10.1% lower than those of the conventional region segmentation methods. It is also shown that the error rates of the proposed information region classification is about 1.7% lower than that of the conventional information region classification method.

• Journal of KIISE:Software and Applications
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• v.27 no.3
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• pp.266-274
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• 2000

Medical image segmentation, which is essential in diagnosis and 3D reconstruction, is performed manually in most applications to produce accurate results. However, manual segmentation requires lots of time to segment, and is difficult even for the same operator to reproduce the same segmentation results for a region. To overcome such limitations, we propose a convenient and accurate semiautomatic segmentation method. The proposed method initially receives several control points of an ROI(Region of Interest Region) from a human operator, and then finds a boundary composed of a minimum cost path connecting the control points, which is the Live-wire method. Next, the boundary is modified to overcome limitations of the Live-wire, such as a zig-zag boundary and erosion of an ROI. Finally, the region is segmented by SRG(Seeded Region Growing), where the modified boundary acts as a blockage to prevent leakage. The proposed User-steered balloon method can overcome not only the limitations of the Live-wire but also the leakage problem of the SRG. Segmentation results of thigh muscles of the Visible Human are presented.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.8
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• pp.225-231
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• 2013

Medical image segmentation is an image processing technology prior to performing various medical image processing. Therefore, a variety of methods have been researched for fast and accurate medical image segmentation. Accurate judgment of segmentation region is needed to segment the interest region in which patient requested in medical image that various organs exist. However, an case that scanned a part of organs is small occurs. In this case, information to determine the segmentation region is lack. consequently, a removal of segmentation region occurs during the segmentation process. In this paper, we improved segmentation results in a small region using volume data and linear equation. In order to verify the performance of the proposed method, we segmented the lung region of chest CT images. As a result of experiments, we confirmed that image segmentation accuracy rose from 0.978 to 0.981 and standard deviation also improved from 0.281 to 0.187.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.38 no.6
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• pp.70-81
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• 2001

This paper presents a 3D face modeling method using a CCD camera and a projector (LCD projector or Slide projector). The camera faces the human face and the projector casts white stripe patterns on the human face. The 3D shape of the face is extracted from spatial and temporal locations of the white stripe patterns on a series of image frames. The proposed method employs region segmentation and multi-beam techniques for efficient 3D modeling of hair region and faster 3D scanning respectively. In the proposed method, each image is segmented into face, hair, and shadow regions, which are independently processed to obtain the optimum results for each region. The multi-beam method， which uses a number of equally spaced stripe patterns, reduces the total number of image frames and consequently the overall data acquisition time. Light beam calibration is adopted for efficient light plane measurement, which is not influenced by the direction (vertical or horizontal) of the stripe patterns. Experimental results show that the proposed method provides a favorable 3D face modeling results, including the hair region.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.45 no.2
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• pp.1-9
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• 2008

In this paper, to extract object regions in stereo image, we propose an enhanced algorithm that extracts objects combining both of brightness information and disparity information. The approach that extracts objects using both has been studied by Ping and Chaohui. In their algorithm, the segmentation for an input image is carried out using the brightness, and integration of segmented regions in consideration of disparity information within the previously segmented regions. In the regions where the brightness values between object regions and background regions are similar, however, the segmented regions probably include both of object regions and background regions. It may cause incorrect object extraction in the merging process executed in the unit of the segmented region. To solve this problem, in proposed method, we adopt the merging process which is performed in pixel unit. In addition, we perform the bi-directional stereo matching process to enhance reliability of the disparity information and supplement the disparity information resulted from a single directional matching process. Further searching for disparity is decided by edge information of the input image. The proposed method gives good performance in the object extraction since we find the disparity information that is not extracted in the traditional methods. Finally, we evaluate our method by experiments for the pictures acquired from a real stereoscopic camera.

• Applied Microscopy
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• v.41 no.2
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• pp.99-107
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• 2011

Light microscope, and scanning and transmission electron microscopy were used to investigate the fine structure of sperm of the Korea squirrel, Tamias sibiricus. The sperm head of T. sibiricus was paddle in shape. The total length of T. sibiricus sperm was 67.8 ${\mu}m$. The length of sperm head was 7.8 ${\mu}m$, and the tail (60.0 ${\mu}m$) was consisted of four major segments: the neck (1.0 ${\mu}m$), middle (8.0 ${\mu}m$), principal (48.5 ${\mu}m$) and end piece (2.5 ${\mu}m$), respectively. Especially, the length of the middle piece is short, and end piece was very shorter than those of other rodents. The post-nuclear cap was occupied about a fifth of nucleus. The equatorial segment is located between the post-nuclear cap segment and acrosomal cap on the nuclear surface. Nine segmented columns were surrounded by the mitochondria, and numbers of gyres of mitochondria were 26. One segmented column was consisted ten to twelve knobs, and each of segmented column in the neck region connected with the nine outer dense fiber in the middle piece. Numerous satellite-like fibers were scattered around the segmented columns. Nos. 1, 5 and 6 of the outer dense fibers in the middle piece were larger than the others. A fibrous sheath and longitudinal column of the principal piece were in evidence, but the fibrous sheath and longitudinal column was not seen at the end piece. In conclusion, the structural features of sperm head and tail may be useful information to patterns of sperm evolution and classification of species.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.3A
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• pp.268-275
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• 2002

This paper proposes a region-based segmentation algorithm fur extracting a video object by using the cost of potential of frame-difference energies. In the first step of a region-based segmentation using spatial intensity, each frame is segmented into a partition of homogeneous regions finely so that each region does not contain the contour of a video object. The fine partition is used as an initial partition for the second step of spatio-temporal segmentation. In spatio-temporal segmentation, the homogeneity cost for each pair of adjacent regions is computed which reflects the potential between the frame-difference energy on the common contour and the frame-difference energy of the lower potential region of the two. The pair of adjacent regions whose cost is minimal then is searched. The two regions of minimum cost ale merged, which result in updating the partition. The merging is recursively performed until only the contours remain which have Same difference energies of high potential. In the fecal step of post-processing, the video object is extracted removing the contours inside the object.

• The Journal of the Korea institute of electronic communication sciences
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• v.17 no.1
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• pp.173-180
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• 2022

Approximate Computing is a promising method for designing hardware-efficient computing systems. Approximate multiplication is one of key operations used in approximate computing methods for high performance and low power computing. An approximate 4-2 compressor can implement hardware-efficient circuits for approximate multiplication. In this paper, we propose an approximate multiplier with low area and low power characteristics. The proposed approximate multiplier architecture is segmented into three portions; an exact region, an approximate region, and a constant correction region. Partial product reduction in the approximation region are simplified using a new 4:2 approximate compressor, and the error due to approximation is compensated using a simple error correction scheme. Constant correction region uses a constant calculated with probabilistic analysis for reducing error. Experimental results of 8×8 multiplier show that the proposed design requires less area, and consumes less power than conventional 4-2 compressor-based approximate multiplier.