• The Journal of Korean Medicine
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• v.27 no.4
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• pp.57-61
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• 2006

Objectives : With an assumption of traditional oriental medical theory, to evaluate the effect of tonification/sedation manipulative acupuncture on blood pressure in male normotensives. Methods : This study was a randomized cross-over trial. We enrolled healthy male normotensive subjects, and assigned them randomly to group A or group B. Group A received acupuncture therapy on Shen-Men (He-7) and Nei-Kuan (EH-6) with tonification-manipulation, while group B received it with sedation-manipulation. Blood pressure was assessed every ten minutes for 2 hours. After 3 days of washout period, the subjects were crossed over to the other manipulation, and the same procedures were performed. Results : We observed that blood pressure stimulated by the sedation-manipulation had a tendency to decrease compared to that by the tonification-manipulation. Conclusions : We suggest the sedation manipulation has more synergic effect with the inhibitory effects of Shen-Men and Nei-Kuan on the sympathetic nervous system than the tonification-manipulation.

• Korean Journal of Acupuncture
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• v.39 no.3
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• pp.91-96
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• 2022

Objectives : The purpose of this study was to characterize the stimulation intensity in acupuncture manipulation techniques for tonification and sedation therapy. Methods : To describe the level of stimulation used in acupuncture manipulation techniques for tonification and sedation therapy, we reviewed the acupuncture manipulation techniques described in classical medical textbooks. Results : Based on the patients' conditions and pattern identification, acupuncture manipulation strategies for tonification and sedation therapy were chosen. For example, the excess condition was treated with sedative therapy, and the deficiency condition was treated with tonification therapy. For tonification therapy, weak to modest stimulation was applied in acupuncture manipulation techniques, whereas intense stimulation was applied for sedative therapy. Even though the intensity of acupuncture stimulation was chosen based on the clinical examination, deqi sensation is a crucial component of acupuncture treatment, and during acupuncture practice, the practitioner should choose the right intensity of acupuncture stimulation based on deqi response in each patient. Conclusions : We concluded that the tonifying and sedative effects of acupuncture treatment are related to the stimulation intensity of acupuncture manipulation techniques. For individualized medicine, the right amount of acupuncture stimulation should be administered based on the patients' conditions and responses, such as deqi responses.

• Korean Journal of Acupuncture
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• v.25 no.4
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• pp.133-145
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• 2008

Objectives : The purpose of this study was to exam the effectiveness of acupuncture using the tonification & sedation manipulation for LI4(Hegu) and KI7(Fuliu) which was known to promote sweating for lack sweating and inhibit for excessive sweating. Methods : The subject of this study was 60 people who agreed with participating. The participants were divided into 6 groups as control group without acupuncture, acupuncture group with needle inserted perpendicularly at LI4, KI7 without manipulation(AT-A), acupuncture group with needle inserted and twisted at LI4 using sedation technique and KI7 using tonificaton technique(AT-B), acupuncture group with needle inserted and twisted at LI4 using tonificaton technique and KI7 using sedation technique(AT-C), acupuncture group with needle inserted and twisted at LI4 and KI7 using tonificaton technique(AT-D) and acupuncture group with needle inserted and twisted at LI4 and KI7 using sedation technique(AT-E). We obtained baseline data at a stable condition with the temperature of $25^{\circ}C$. After having the participant stay at $40^{\circ}C$ for 10 minute and treated with acupuncture for 10 minute, we measured the parameters such as sweating rate, water content in subcutaneous, water content in skin surface, systolic blood pressure, diastolic blood pressure, pulse rate, oxygen saturation and body temperature. Results : After the tonification & sedation manipulation at LI4 and KI7, the sweating rate was significantly decreased in AT-B, AT-D and AT-E groups. The water contents in skin surface was significantly decreased in AT-B and AT-E groups. The water contents in subcutaneous was significantly decreased in AT-B, AT-C, AT-D and AT-E groups. However, there were no significant changes in systolic blood pressure, diastolic blood pressure, pulse rate, oxygen saturation and body temperature. Conclusions : Acupuncture at LI4 and KI7 is effective in controling sweating, and the effect varies according to the tonification & sedation manipulation technique.

• The Journal of Korean Medicine
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• v.28 no.4
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• pp.69-73
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• 2007

Objectives : With an assumption of the traditional oriental medical theory, we were to evaluate the effect of tonification/sedation-manipulated acupuncture on autonomic nervous activity in healthy subjects. Methods : This study is a randomized cross-over trial. We enrolled healthy subjects, and assigned them randomly into group A or group B. Group A received acupuncture therapy on Shen-Men (He-7) and Nei-Kuan (EH-6) with tonification-manipulation, while Group B received it with sedation-manipulation. Their heart rate variability was monitored for 2 hours. After 3 days of washout period, the subjects were crossed over to the other manipulation method, and the same procedures were performed. Results : There was no statistical significance in the change of RR, SDNN, LF, HF, and LF/HF ratio between the tonification-manipulated and the sedation-manipulated groups. However, HF curve in the tonification manipulated group showed increasing tendency for 15 minutes after acupuncture. Conclusions :We suggest that the traditional tonification-manipulated acupuncture on Shen-Men and Nei-Kuan could increase parasympathetic activity shortly after acupuncture, but further evaluation on a larger sample size is needed to confirm this suggestion.

• Korean Journal of Acupuncture
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• v.26 no.4
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• pp.23-38
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• 2009

Objectives : The purpose of this study was to identify the effect of the tonification & sedation manipulation for LI4 and KI7 on lacking of sweating in cold environment. Methods: The participants were divided into 3 groups as intact group without acupuncture, acupuncture group inserting and twisting with LI4 tonificaton and KI7 sedation method(LI4-tonify KI7-purge) and acupuncture group inserting and twisting with LI4 sedation and KI7 tonificaton method(LI4-purge KI7-tonify). We obtained baseline data at cold condition with the temperature $14{\pm}1^{\circ}C$. After making the participant staying in cold condition for 10 minute, we measured sweating rate in skin surface, body temperature, oxygen saturation, pulse rate, systolic blood pressure, diastolic blood pressure, deoxy-Hb and oxy-Hb in subcutaneous. Results : After acupuncture in cold environment, the sweating rate in skin surface significantly decreased in KI7-purge LI4-tonify group comparing the intact groups. The body temperature significantly increased in LI4-tonify KI7-purge and LI4-purge KI7-tonify groups comparing the intact group. The oxygen saturation significantly increased in LI4-tonify KI7-purge group comparing the intact group. Conclusions : These findings indicated that LI4 tonificaton and KI7 sedation method(LI4-tonify KI7-purge) could be effective for production of sweating in cold condition.

• Korean Journal of Acupuncture
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• v.27 no.2
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• pp.203-216
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• 2010

Objectives : The purpose of this study is to identify the effect of tonifying or sedative manipulation on LI4 and KI7 for sweet deficiency under cold environment. Methods : The participants were divided into 4 groups; intact group without acupuncture(Intact), acupuncture group inserting straightly with LI4 & KI7 method((LI4-straight KI7-straight), acupuncture group inserting twisting with LI4 tonificaton & KI7 tonificaton method(LI4-tonify KI7-tonify) and acupuncture group inserting twisting with LI4 sedation & KI7 sedation method(LI4-purge KI7-purge). We obtained the baseline data under cold condition with the temperature $14{\pm}1^{\circ}C$. After making the participant staying under cold condition for 10 minute, we measured sweating rate on skin surface and biological responses such as body temperature, oxygen saturation, pulse rate, systolic blood pressure, diastolic blood pressure, deoxy-Hb and oxy-Hb in subcutaneous. Results : The sweating rate on skin surface was not different in all treatment groups compared to the intact group. The body temperature was significantly increased in LI4-straight KI7-straight group compared to the intact group. The oxygen saturation significantly increased in LI4-purge KI7-purge group compared to the intact group. The systolic blood pressure was significantly increased in LI4-purge KI7-purge group compared to the intact group. The deoxy-Hb was significantly decreased in LI4-purge KI7-purge group compared to the intact group. Conclusions : The above results, the effect of LI4, KI7 acupuncture due to the tonifying or sedative manipulation on sweating control could be observed. However, other biological responses with the acupuncture of tonifying or sedative manipulation were giving different expressions. We suggest that continued research of tonifying or sedative manipulation is of importance order to find these expressions.

• Journal of Veterinary Clinics
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• v.14 no.2
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• pp.151-160
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• 1997

This study was performed to assess clinical signs, sedative and physiologic effects of a combination of fentanyl, azaperone and xylazine (F-A-X). The experiments were divided into four groups; xylazine 0.1mg/kg (X 0.1), F-A-X 0.05 MG/KG (F-A-X 0.05), F-A-X 0.1 MG/KG (F-A-X 0.1) and F-A-X 0.2mg/kg (F-A-X 0.2). Heart rates were decreased in all groups. Respiratory rates were decreased in other groups, but increased in F-A-X 0.2. Body temperatures were in normal ranges. After administration of F-A-X, most of cattle were recumbency and did not respond to needle prick. Duration of sedation was prolonged with increasing dosages. F-A-X did not induce sufficient analgesia for dehorning. Side effects were salivation and urination in all, but they were much less in F-A-X groups than those in X 0.1. Intermittent apnea and bloat were observed in F-A-X 0.2. Serum chemistry values were in normal ranges exvept for hyperglycemia invreased thorough experimental time. Based on above results, it may be concluded that F-A-X is effective preanesthetic with low dosage of 0.05~0.1 mg/kg being useful for immobilization or manipulation without tissue incision in cattle.

• Korean Journal of Acupuncture
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• v.31 no.4
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• pp.179-187
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• 2014

Objectives : Saam acupuncture initiated by Saamdoin is traditional and originative method, which is characterized by applying the five phases theory and mother-child reinforcement-reduction principle to the selection of acupoints and needling manipulation. Our study was aimed to summarize and assess the use of acupoint SP3(Taebaek) in Saam acupuncture treatment and to further understand Saam acupuncture in an aspect of the combination of acupoints. Methods : We searched the data based on "(Do Hae Kyo Kam) Sa-Ahm's acupuncture method" for SP3 used and acupoint combination including SP3. We performed frequency analysis, network analysis, and cluster analysis for quantitative aspect. To understand clinical implication of SP3 with another acupoint, qualitative and descriptive methods were also carried out. Results and Conclusions : In our study, SP3 was frequently used for tonification of lung, spleen, heart, and kidney meridian and sedation of kidney, heart, and lung meridian. For this, many acupoints such as LU8, LU9, KI3, HT8, KI7, LU10 and LR1 were used with SP3. The combination of SP3 and other acupoints were used to treat stroke, common cold, and pain conditions including headache, low back pain, respiratory disease as well as gastroenteric troubles including stomachache, indigestion, vomiting, and constipation. To further understand Saam acupuncture, an understanding of the five transport points based on five elements characters, pathological changes (deficiency and excess) of viscera and bowels, and concept of source point should be preceded.