• Journal of Life Science
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• 제9권1호
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• pp.45-49
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• 1999

Seaweed alginate was acetylated by activated carbon immobilized Pseudomonas syringae in a fluidized bed, up-flow reactor. The acetylation degree of seaweed alginate was about 30%. Calcium-acetylated seaweed alginate gel bead was made and compared to calcium-seaweed alginate gel bead by the scanning electron microscopy (SEM). Structural difference of two gel beads may results from increased viscosity and decreased affinity of acetylated seaweed alginate for calcium ion. On the basis of interior and exterior structure of calcium-acetylated seaweed alginate gels and property of acetylated seaweed alginate, it seems that acetylated seaweed alginate is used for the supporter for electrophoresis and packing materials for liquid chromatography and gel filtration.

• 한국응용과학기술학회지
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• 제29권4호
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• pp.599-609
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• 2012

이 연구의 목적은 버려진 굴 패각을 재활용하여 감소시키는 것으로 굴 패각과 해조펄프를 이용하여 식품의 보존에 대한 항산화비드를 활용하는데 있다. 이 연구는 두 부분으로 나누었다. 첫 번째는 파일럿 규격조건으로 설계하고 제조하였다. 둘째는 [A],[B],[C-a],[C-b]화합물에 대한 최적제조 조건을 다루어 확립하고 이들 생성물을 분석하였다. 파일럿 규격 제조는 해조펄프의 분자수식합성과/Cl-전분 그리고 그의 다양한 비드 형태들이 극성용매에서 다양한 중량비율로 액상 혼합하여 제조되었다. 부가적으로, 혼합과정에서 해조펄프의 비율이 증가함으로서, 해조펄프/Ag-굴 패각을 섞인 것의 항균성은 감소되었으나 항산화와 비드의 견고성 성질은 증가되었다. 파일럿 규격의 생성라인은 해조 펄프와 Cl-전분을 분자수식으로 합성하였다. 그리고 극성용매를 사용하여 여러 가지 중량비율로 다양한 형태의 비드를 제조하였다.

• 산업식품공학
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• 제13권4호
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• pp.269-274
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• 2009

습식분쇄의 최적조건을 얻고자 부형제 종류, 농도, 습식 분쇄시 rotor speed, bead size, feed rate, 분쇄회수를 달리하여 분쇄한 결과, 부형제로는 gum arabic을 사용하여 5%의 농도로 첨가할 때 가장 좋은 분쇄효과를 나타내었다. Rotor speed를 달리하여 습식분쇄한 결과, rotor speed가 증가할수록 좋은 결과를 나타내어 4,000 rpm에서 가장 우수한 것으로 나타났다. 원료와 직접 부딪혀 분쇄를 하게 되는 bead는 0.4 mm의 크기를 사용하였을 때 가장 작은 사이즈로 분쇄되는 것으로 나타났다. 분쇄가 이루어지는 chamber내에 원료를 공급하는 비율에 따른 결과에서는 40 L/h 의 속도로 공급했을 때 가장 작은 입도분포를 보였다. 분쇄회수에 따른 영향은 횟수에 따라서는 8회 이상으로 분쇄하였을때 0.6 $\mu$m이하의 입도분포가 90% 이상으로 나타나 10회를 분쇄하였을때 가장 좋은 효과를 나타내었다. 연속운전과 비연속운전의 비교에서는 연속운전이 더 효율적이었으며 부형제 종류에 따른 영향은 gum arabic을 첨가하여 분쇄하였을때 가장 우수한 결과를 나타내었다. 따라서 적절한 농도와 종류의 부형제 사용과 rotor speed, bead size, feed rate, 용매와의 혼합비의 최적공정을 수립한 습식 분쇄기술로 초미세액상칼슘의 제조가 가능하였고, 습식분쇄기술을 식품가공기술로 활용할 수 있는 가능성을 확보하였다.

• 한국환경보건학회지
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• 제27권1호
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• pp.83-87
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• 2001

In this study, the characteristics of lead removal by PVA and alginate bead which used widely as immobilizing agents were investigated, and the difference of removal amounts between pure PVA/alginate bead and Sargassum thunbergii immobilized bead was studied. All PVA beads, pure and S. thunbergii immobilized, reached an equilibrium state in about 1 hour, and S. thunbergii immobilized bead adsorbed more lead than pure one. But in the case of alginate beads, they needed much time, about 5 hours, to reach an equilibrium state, and adsorbed lead four times higher than PVA beads. Therefore, it was considered that alginate beads had more mass transfer resistance and function groups which adsorb lead such as hydroxyl, carboxyl and etc. than PVA bead. To examine the continuous usage of alginate beads, the process of adsorption/desorption of lead was conducted repeatedly. As the process proceeded, the amounts of lead adsorption decrease, so it was indicated that the non-desorbed lead from alginate bead at first adsorption/desorption process remained constantly.

• Journal of Pharmaceutical Investigation
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• 제25권2호
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• pp.153-161
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• 1995

Alginic acid is a hydrophilic , colloidal polysaccharide obtained from cell wall of seaweed or brown algae and has a broad range of applications. Alginlc acid becomes alginate gel bead due to its cation-induced gelation. Dried alginate beads can be reswollen according to environmental pH. The purpose of this paper is to explore the possible applicability of alginate beads as an oral controlled release system of ibuprofen. In this experiment ibuprofen was incorporated in alginate beads and alginate beads were treated with various methods. Ibuprofen release from alginate beads in phosphate buffer (pH 7.4) was laster than in distilled water and dilute HCl. The release of ibuprofen was more sustained in bead than simple mixture and coprecipitate of ibuprofen and sodium alginate. The dissolution rate of ibuprofen was decreased in using of bead that hardened with formaldehyde. The dissolution rate of the drug from the bead was the fastest in 12 hour dried beads, 1.5%-sodium alginate concentration and 1%-calcium chloride concentration. Sodium alginate bead can be used as a sustaind release drug delivery system of water-insoluble drugs.

• 한국수산과학회지
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• 제54권4호
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• pp.561-567
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• 2021

The edible sargasso seaweed hijiki Sargassum fusiforme is known to have high concentration of arsenic, which is a threat to human health, particularly due to inorganic arsenic. In this study, various methods were used to remove inorganic arsenic from steamed hijiki concentrate. The highest concentration of arsenate [As(V)] in both raw and processed hijiki during steamed hijiki manufacturing process was within the range of 8.213-14.356 mg/kg, and it is a potential source of inorganic arsenic, which can result in re-contamination and cause environmental pollution. The removal efficiencies of the various removal methods were within the range of 57.3-83.4%, and 19.0% reduction was achieved using activated carbon and alginate bead. Further, activated carbon showed the best adsorption effect of inorganic arsenic. Therefore, we suggest that activated carbon is a suitable efficient method for removing inorganic arsenic and has low operational costs in field applicability.