• Journal of the Korean Society of Tobacco Science
• /
• v.29 no.2
• /
• pp.110-117
• /
• 2007

In vitro toxicity tests such as cytotoxicity, mutagenicity and genotoxicity assay are useful for evaluating the relative toxicity of smoke or smoke condensates obtained from different cigarette configurations. A major disadvantage of these tests is relatively time-consuming, complicated and expensive. Recently, a cell-free glutathione consumption assay (GCA) as a rapid and simple screening method for the toxicity assessment of smoke has been reported by Cahours et al. (CORESTA, 2006). This study was carried out to assess the GCA application capable of predicting the toxicity of gas/vapor phase (GVP) of cigarette smoke and to identify individual compounds responsible for the glutathione (GSH) consumption in smoke. Each GVPs from 2R4F, standard cigarette, carbon filter cigarette (ExC) and new carbon filter cigarette (ExN), test cigarettes were collected by automatic smoking machine and evaluated the relative toxicity by GCA and neutral red uptake (NRU) assay. Toxic compounds existed in smoke were also chosen, relative toxicities of these compounds were screened by using two methods and compared individually. The overall order of toxicity by GCA was 2R4F > ExC > ExN, which was consistent with the result of Neutral Red Uptake assay. The levels of carbonyl compounds of ExN were lower than those of 2R4F and ExC, indicating that GSH consumption was associated with carbonyl compound yields. A major toxicant under current study is acrolein, which contributed to more than half of the GSH consumption. Collectively, the toxicity of GVP determined by GCA method may be mainly attributed to acrolein.

• Korean Journal of Community Nutrition
• /
• v.9 no.6
• /
• pp.725-733
• /
• 2004

It was well received that well grounded behavioral theories were important in the development of effective nutrition education programs, but there are only a few programs available for Korean women. The objective of this study was to develop nutrition education programs for childbearing-aged women in Korea. Based on the findings of the needs assessment for the program and theoretical backgrounds, we developed behaviorally oriented tailored nutrition education program including motivation (MT), modifying (MD) and maintenance (MA) stages. The key concepts of the stages were motivation promotion for MT, increasing behavioral capabilities for MD, and strengthening self-management and building favorable environmental condition for MA. The education program was intended to be need in individual nutrition counseling, but it could be well used for group education by developing materials using the relevant contents. The primary users of the program were nutrition educators, however it could be also used by clients as needed. The introductory chapter provided dietary assessment tools and nutrition education tips. MT chapter included subjects such as nutritional status screening, costs of inappropriate nutrition and weight management, benefits of eating right, and activities for motivation promotion. MD stage chapter dealt with topics of healthy weight, knowledges and skills for better eating habits and physical activity status, and activities related to setting tailored behavioral objectives. MA stage focused on facilitating self management skills and building helping relationships. Each stage underlined activities using various educational tools in order to promote active participation of the client (s). For better use of this program, it was recommended to conduct program validation study.

• Journal of the Korea Institute of Building Construction
• /
• v.10 no.1
• /
• pp.221-228
• /
• 2010

A construction firm's performance is largely attributable to performance in individual projects. In this regard, the awarding of an individual project has significant implications. However, project awards have received limited attention in the construction sector from amarket assessment perspective. This event study focuses on an analysis of market responses at the time of project awarding. A total of 252 samples wereselected through a rigorous sample screening processes. Performance was measured as cumulative abnormal return, which is traditionally adopted in event analysis. Research results indicated that the overall return is positive, and that the level isstatistically significant. Equity holders realized a higher return for projects awarded from the foreign countries compared to domestic projects. No relationship was observed between project size and the level of return. Other research findings and implications were discussed in detail from a management perspective.

• Journal of International Academy of Physical Therapy Research
• /
• v.11 no.2
• /
• pp.2096-2101
• /
• 2020

Background: The effect of mobilization on lumbar back pain has been fully described in several clinical aspects, but evidence for muscle strength would be still less clear. Objective: To assess the effect of lumbar mobilization on lower limb strength in healthy individuals. Methods and Analysis: Healthy people aged 18-65 will be included regardless of race or sex. Original peer-reviewed primary reporting randomized controlled trials (RCTs) will be included. Electronic databases, such as MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science, Pedro, CINAHL, ClinicalTrials.gov will be searched from inception until July 30. Only studies published in English will be included in this review. Two reviewers will complete the screening for eligibility independently, and the other two reviewers will also complete the risks of data extraction and bias assessment independently. Lower Limb strength will be assessed as primary outcome, and particular intervention or participant characteristics will be assessed as the secondary outcomes. Meta-analysis will be conducted using Review Manager 5.3.3, and evidence level will be assessed using the method for Grading of Recommendations Assessment, Development and Evaluation. Outcomes will be presented as the weighted mean difference or standardized mean difference with 95% CI. If I² ≤ 50%, P>.1, the fixed effect model will be used, otherwise, random-effects model will be used. Ethics and dissemination: This review might not be necessary ethical approval because it does not require individual patient's data; these findings will be published in conference presentations or peer-reviewed journal articles. PROSPERO registration number: CRD42020150144.

• Journal of Environmental Impact Assessment
• /
• v.21 no.1
• /
• pp.41-51
• /
• 2012

To select 10 representatives for the ecotourism networks around the areas bordering national rivers in Korea, the spatial ranges for ecotourism have been established, the ecotourism potential analyzed, and the ecotourism resources information collected by the Regional Environmental Offices and the Korea National Park Service has undergone reviews, amendments, supplements, and verification processes through familiarization tour previews, and the following main results have been derived. First, the spatial ranges of the eco-tourism networks have been set as the watershed areas that include areas around the four major rivers and the rivers. Second, the areas with high potential value for ecotourism were selected through the analysis of ecotourism potential. Since EGIS was used for the analysis, it was inevitable that insufficient amount of localized information was reflected, and the use of the results as reference for the potential would be feasible. Third, it was possible, by reviewing, amending and complementing the results of ecological resource information collected by the Regional Environmental Offices and the Korea National Park Service, to select 50 representative ecological resources around the national rivers. The selected resources were considered for the adjacency, attractiveness of ecological resources, and uniqueness of the national rivers, and they were derived by screening expert advice, official opinion, and geographical analysis information. Fourth, 10 representative ecotourism networks based on watershed areas were selected, and suitable themes were given based on the resource characteristics. Fifth, the appropriateness for ecotourism has been confirmed, with the familiarization tour previews and survey results, preservation of the future ecotourism resources, and the establishment of the foundation as the basis. In the future, the remaining 9 ecotourism networks would also need to undergo a verification process such as familiarization tours. It is deemed that, through future ecotourism contests, if the programs that select locally-pioneered tourism programs resulting from the capacities of local entities and residents, then it would be more effective in discovering resources that are more localized and of higher regional value.

• Journal of Korean Ophthalmic Optics Society
• /
• v.13 no.4
• /
• pp.109-114
• /
• 2008

Purpose: To assess the reproducibility and repeatability for each color vision test method. Methods: The subjects for color vision test were 30 students without congenital color vision deficiency and they major in optometry in a university, Korea. The type of color vision test selected for this study were Hans color vision test, Hans 15 hue test and Lanthony D 15 hue test. The Ishihara test was added for assessment of reliability of inter-tester. Results: All of the subjects were classified into normal at pseudoisochromatic plates, but one subject's result showed mild blue-yellow color deficiency at Hue discrimination. Results of 3 repeated test for subjects and inter-tester examination showed no errors at pseudoisochromatic plates. There were differences in mild errors among repeated test at Hue discrimination, but no differences were found in the results of repeated test to classify color vision deficiency. Conclusion: Each tester had better be more skilled to test even simple color vision test for eliminating the possibility of mild errors. Each subject might just as well be careful in color vision test. It is required to test both method of pseudoisochromatic plates and Hue discrimination in screening test.

• Korean Journal of Construction Engineering and Management
• /
• v.19 no.5
• /
• pp.53-60
• /
• 2018

In particular, the investigation of tendons in PSC Box Girder Bridge should be done in a systematic way. It is important to identify preventative maintenance activities that should be carried out in order to analyze the risk factors by type of representative tensions and to reduce risks in the long term. However, in the current maintenance system, various methodologies for investigating and repairing tensions have been studied, but it is difficult to investigate precisely tensions. Therefore, to apply the risk assessment for screening of tensions to the domestic PSC Box Bridge, we presented a risk matrix evaluation index that is consistent with the state assessment and maintenance system.

• Anxiety and mood
• /
• v.14 no.2
• /
• pp.135-141
• /
• 2018

Objective : This study evaluated the role of smartphone application in the self-assessment of three psychiatric symptoms: stress, depression, and suicidal ideation. Methods : A total of 5,646 respondents were evaluated with three scales (Perceived Stress Scale, PSS, Center for Epidemiologic Study for Depression, CES-D, Scale for Suicidal Ideation, SSI) via smartphone application 'mindscan'. We analyzed the sociodemographic variables, the levels of three symptoms, and the association between the scores on all three scales. Results : The mean total scores of PSS, CES-D, and SSI were 24.86, 35.15, and 18.03, respectively. Women showed significantly higher scores on PSS, CES-D, and SSI when compared with men. Younger users showed a significantly higher score on all three scales when compared with older users. The scores on all three scales were higher than in other studies with off-line surveys. The PSS was positively correlated with CES-D (r=0.690), and with SSI (r=0.367). The CES-D was positively correlated with SSI (r=0.540). Conclusions : A smartphone application for mental health based on three scales (PSS, CES-D, and SSI) is a relatively useful screening tool compared with off-line general population surveys. The association between the three scales reflects the relationship between the three psychiatric symptoms observed in clinical practice.

• The Journal of Internal Korean Medicine
• /
• v.39 no.6
• /
• pp.1105-1115
• /
• 2018

Objectives: The aim of this review is to investigate clinical studies on Oriental medicine treatment for aphasia after cerebrovascular disease. Methods: Using the keywords 'Aphasia', 'Oriental medicine', 'Stroke' 'Cerebral infarction', 'Cerebral hemorrhage', and 'Clinic', we searched domestic databases, including "NDSL (National Discovery for Science Leaders)", "Korean Traditional Knowledge Portal", "OASIS (Oriental Medicine Advanced Searching Integrated System)", and "RISS (Research Information Sharing Service)". Each keyword was not searched individually, but combined in various ways. To investigate recent trends, we limited our search to papers published after 2000. Papers that did not include a specific treatment method or did not match the subject "Aphasia after stroke" were excluded. Results: Using the searching method, 13 studies were found. Of these, 12 studies were in the form of case reports, while one was in the form of a non-randomized controlled trial. These studies showed positive results for the use of Oriental medicine in terms of the Korean version of the Western Aphasia Battery (K-WAB), the evaluation form on functional performance capability and accuracy of articulatory organs developed by Lee, aphasia screening test refered in 'Assessment in Speech-Language Pathology' and adapted properly to Korean, the Communicative Ability in Daily Living Test (CADLT), the Korean Version-Boston Naming Test (K-BNT), and language assessment items included in CNS, and NIHSS. Conclusions: Of the 12 case reports, 11 studies showed positive results of the use of Oriental medicine for treatment of aphasia after cerebrovascular disease. However, more sophisticated and large-scale clinical research on aphasia should be conducted.

• Nutrition Research and Practice
• /
• v.15 no.4
• /
• pp.504-515
• /
• 2021

BACKGROUND/OBJECTIVES: Malnutrition risk and malnutrition among the elderly is a public health concern. In combating this health-related problem, it is critically important to evaluate the risk factors in a multidimensional way and to apply appropriate nutrition intervention based on the results. SUBJECTS/METHODS: A cross-sectional study was conducted on 215 elderly patients (32.6% male, 67.4% female) in a geriatric outpatient clinic of a hospital in Turkey. Nutritional questionnaires that incorporated the 24-h recall method were applied to determine general characteristics of patients, their health status, nutritional habits, and daily energy and nutrient intakes. Mini Nutritional Assessment was used to determine nutritional status. Relevant anthropometric measurements were obtained. RESULTS: The subjects' mean age was 76.1 ± 7.0 years, and the prevalence of malnutrition (n = 7) and risk of malnutrition (n = 53) among the 215 subjects was 3.2% and 24.7%, respectively. Patients with malnutrition or risk of malnutrition were found to be single, have a depression diagnosis, in an older age group, have less appetite, more tooth loss, have more frequent swallowing/chewing difficulty, and have more frequent meal skipping. In addition, mean daily energy, carbohydrate, fat, fiber, vitamin E, vitamin B1, vitamin B2, vitamin B6, vitamin C, folates, potassium, magnesium, phosphorus, iron intake, and water consumption were found to be statistically significantly low in subjects with malnutrition or risk of malnutrition. After performing regression analysis to determine confounding factors, malnutrition risk was significantly associated with marital status, loss of teeth, appetite status, and depression. CONCLUSIONS: Routine nutritional screening and assessment of the elderly should be performed. If nutritional deficiencies cannot be diagnosed early and treated, self-sufficiency in the elderly may deteriorate, resulting in increased institutionalization.