• Title/Summary/Keyword: screening assessment

Search Result 609, Processing Time 0.025 seconds

Current status of development and event-dependent genetic analysis of genetically modified crops in Korea (우리나라의 유전변명작물 개발 현황 및 사상-종속 유전 분석)

  • Jeong, Soon-Chun
    • Journal of Plant Biotechnology
    • /
    • v.35 no.1
    • /
    • pp.23-29
    • /
    • 2008
  • Development of genetically modified crops using modern biotechnology is regarded as a promising way to combat with ever-increasing human population. Korea attempted to develop its own genetically modified crops essentially for the past 20 years, however no example of commercialization has been announced. Here, I briefly summarized current status of development and risk assessment of genetically modified crops in Korea. Then, I attempted to identify a death valley in the process of commercialization. Based on experience of risk assessment of 15 different genetically modified organisms, I suggested that lack of the screening of elite events may serve as a death valley.

Estimating Predicted Environmental Concentration of Veterinary Antibiotics in Manure and Soil

  • Kwon, A-Young;Kim, Sung Chul
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.48 no.2
    • /
    • pp.100-104
    • /
    • 2015
  • Adverse effect of veterinary antibiotics (VAs) released into environment has been issued recently and concerns about analysis and management for VAs in the environment were increased. Main objective of this research was to calculate predicted environmental concentration (PEC) of the VAs in soil based on avaiable statistical data and result of previous study such as consumption rate and physiological properties of VAs. Total of 5 VAs, Chlortetracycline (CTC), Oxytetracycline (OTC), Sulfadimethoxine (SDX), Sulfamethazine (SMT), and Tylosin (TYL) were examined. Result showed that calculated PEC value in manure and soil was ordered as SMT > TYL > SDX > CTC > OTC. Range of calculated value for manure and soil was 0.50-67.04 and $0.48-64.45mg\;kg^{-1}$ respectively. Comparing to measured concentration of VAs in manure and soil, lower concentration of VAs in manure and soil was evaluated due to fate and degradation of VAs in manure and soil. Overall, evaluated simple modeling for calculating PEC of VAs in manure and soil can be adapted for preliminary screening purpose in environmental risk assessment and more refined modeling is necessary to examine detailed assessment of VAs in manure and soil.

A pilot study for restandardization of CDI( Child Development Inventory) in Korea (K-CDI 아동발달검사 표준화를 위한 예비연구)

  • Kim, Jeong-Mee;Shin, Hee-Sun
    • Child Health Nursing Research
    • /
    • v.12 no.2
    • /
    • pp.260-267
    • /
    • 2006
  • Purpose: This pilot study was to develop Korean version of CDI(The Child Development Inventory) and assess the validation and reliability on K-CDI. Method: The K-CDI is assessed by parent-report method that has designed to screen children developmental functioning on 12 months to 6.5 years of age /or older children who are judged to be functioning in the one to six-year range. The inventory assesses areas of child development in the social, self-help, motor, language, letter and number skills. also, it includes various symptoms and behavior problems that young children may have. Participants were 130 children and their mothers who has lived in Seoul or Gyounggi-Do. Data was analyzed on the ratio of item response, Pearson's correlation, and Cronbach alpha. Results: 270 items with 8 sub-developmental realms were confirmed the reliabilities and validity on Korean children. Total 300 items were selected for restandardization. There was a significant correlation between the score of Social Maturity Scale and K-CDI. The corrlation coefficient alpha was .98. Conclusion: This study indicated that CDI is applicable in the clinical and early childhood educational setting for developmental assessment in Korea.

  • PDF

Preventive Control Using Generation Rescheduling for Transient Stability (과도안정도 측면에서의 발전 재배분을 이 용한 예방제어)

  • Lee, Jong-Seok;Lee, Byeong-Jun;Gwon, Se-Hyeok;Choe, Seon-Gyu;Nam, Hae-Gon;Chu, Jin-Bu;Jeon, Dong-Hun
    • The Transactions of the Korean Institute of Electrical Engineers A
    • /
    • v.51 no.6
    • /
    • pp.262-268
    • /
    • 2002
  • Preventive control has to solve two important problems. The first is fast and accurate severity assessment of instability originated from the occurrence of a dangerous contingency. The second is to choose an action able to stabilize it. In this paper we assess contingencies in power systems using PASF(Power Angle Shape Filtering) and control power systems by a generation rescheduling. The control action stabilize the whole set of harmful contingencies simultaneously. Note that conventional time-domain transient stability methods can hardly tackle preventive control. So, we study the preventive control using off-line method. The proposed method is applied to prevent and to correct loss of synchronism of all the generators in a operating systems data.

Statistical Approach to Noisy Band Removal for Enhancement of HIRIS Image Classification

  • Huan, Nguyen Van;Kim, Hak-Il
    • Proceedings of the KSRS Conference
    • /
    • 2008.03a
    • /
    • pp.195-200
    • /
    • 2008
  • The accuracy of classifying pixels in HIRIS images is usually degraded by noisy bands since noisy bands may deform the typical shape of spectral reflectance. Proposed in this paper is a statistical method for noisy band removal which mainly makes use of the correlation coefficients between bands. Considering each band as a random variable, the correlation coefficient measures the strength and direction of a linear relationship between two random variables. While the correlation between two signal bands is high, existence of a noisy band will produce a low correlation due to ill-correlativeness and undirectedness. The application of the correlation coefficient as a measure for detecting noisy bands is under a two-pass screening scheme. This method is independent of the prior knowledge of the sensor or the cause resulted in the noise. The classification in this experiment uses the unsupervised k-nearest neighbor algorithm in accordance with the well-accepted Euclidean distance measure and the spectral angle mapper measure. This paper also proposes a hierarchical combination of these measures for spectral matching. Finally, a separability assessment based on the between-class and within-class scatter matrices is followed to evaluate the performance.

  • PDF

Assessment of Developmental Toxicants using Human Embryonic Stem Cells

  • Hong, Eui-Ju;Jeung, Eui-Bae
    • Toxicological Research
    • /
    • v.29 no.4
    • /
    • pp.221-227
    • /
    • 2013
  • Embryonic stem (ES) cells have potential for use in evaluation of developmental toxicity because they are generated in large numbers and differentiate into three germ layers following formation of embryoid bodies (EBs). In earlier study, embryonic stem cell test (EST) was established for assessment of the embryotoxic potential of compounds. Using EBs indicating the onset of differentiation of mouse ES cells, many toxicologists have refined the developmental toxicity of a variety of compounds. However, due to some limitation of the EST method resulting from species-specific differences between humans and mouse, it is an incomplete approach. In this regard, we examined the effects of several developmental toxic chemicals on formation of EBs using human ES cells. Although human ES cells are fastidious in culture and differentiation, we concluded that the relevancy of our experimental method is more accurate than that of EST using mouse ES cells. These types of studies could extend our understanding of how human ES cells could be used for monitoring developmental toxicity and its relevance in relation to its differentiation progress. In addition, this concept will be used as a model system for screening for developmental toxicity of various chemicals. This article might update new information about the usage of embryonic stem cells in the context of their possible ability in the toxicological fields.

Isolated Working Canine Heart Perfusion Apparatus for Evaluation of Myocardial Protection Methods (심장기능 평가를 위한 견 적출심장 관류장치의 설계)

  • 이종국
    • Journal of Chest Surgery
    • /
    • v.21 no.2
    • /
    • pp.246-253
    • /
    • 1988
  • An in vitro model providing with a recirculating perfusion apparatus using an isolated canine heart and its autogenous blood, which was prepared for study of myocardial protection method. This apparatus was easily used by quick connect system and maintained well heart function for about 2 hours. The Langendorff perfusion was initiated for a 10 minute period by introducing perfusate at 37` into the aorta from aortic reservoir located 100 cm above the heart. The isolated perfused working canine heart model was a left heart preparation in which oxygenated perfusion medium [at 37K] entered the cannulated left atrium at a constant flow rate [900ml/ min] under 20 mmHg overflow system and was spontaneously ejected[no electrical pacing] via an cannula against a hydrostatic pressure of 80 cm H2O. During this working period, various indices of cardiac function were measured. The cardiac functions were stable for over 2 hours with perfusion of Krebs-Henseleit solution and autologous blood[1:1] mixture in volume and maintained heart rate ]]3-122/bpm peak systolic pressure 109-113 mmHg, cardiac output 900 ml / min and left atrial mean pressure 8-9 mmHg. In this model, the efficiency of myocardia] protection could be easily measured by means of functional, enzymatic, biochemical and ultrastructural assessment. And also, we believe this model to be a useful assessment screening model of recovery state after long duration of myocardial preservation of donor heart without difficult transplantation procedures.

  • PDF

An Analysis of Local Wind Field based on Urban Development (도시개발에 따른 국지 바람장 분석)

  • Song, Dong Woong
    • Journal of Environmental Impact Assessment
    • /
    • v.20 no.2
    • /
    • pp.133-140
    • /
    • 2011
  • A numerical study with Envi-met model is experimented to investigate the characteristics of wind pattern in Gangwon innovation city. In all case, most conditions such as wind speed, temperature, and surface are considered as the same, but wind direction is the only different factor. The wind directions considered in this study have a meaning of prevailing wind direction. When the prevailing wind with the direction of $247^{\circ}$ blows into the city, the ventilation passage toward the outside of city is formed and the stagnation of air is not expressed. In case of having the direction of $270^{\circ}$, most evident ventilation passages are composed. When the inflow wind direction is the north, $0^{\circ}$, there is some possibility of stagnation phenomenon. The case where the representative wind direction of three kind will flow with development, in compliance with the building is caused by with screening effect of some and shows a true stagnation phenomenon, wishes in the park and flowing water and the greens area to be for a long time formed and the wind direction is maintained.

Developing a Best-Evidence Pre-employment Medical Examination: An Example from the Construction Industry

  • Gouttebarge, Vincent;van der Molen, Henk F.;Frings-Dresen, Monique H.W.;Sluiter, Judith K.
    • Safety and Health at Work
    • /
    • v.5 no.3
    • /
    • pp.165-167
    • /
    • 2014
  • The Dutch construction industry has introduced a compulsory preemployment medical examination (PE-ME). Best-evidence contents related to specific job demands are, however, lacking and need to be gathered. After the identification of job demands and health problems in the construction industry (systematic literature search and expert meeting), specific job demands and related requirements were defined and instruments proposed. Finally, a work ability assessment was linked to the instruments' outcomes, resulting in the modular character of the developed PE-ME. Twenty-two specific job demands for all Dutch construction jobs were identified, including kneeling/squatting, working under time pressure, and exposure to hazardous substances. The next step was proposing self-report questions, screening questionnaires, clinical tests, and/or performance-based tests, leading to a work ability judgment. "Lifting/carrying" is described as an example. The new modular PE-ME enables a job-specific assessment of work ability to be made for more than 100 jobs in the Dutch construction industry.

Menstrual Cycle Characteristics and Premenstrual Syndrome Prevalence Based on the Daily Record of Severity of Problems in Korean Young Adult Women

  • Kim, Yae-Ji;Park, Young-Joo
    • Journal of Korean Academy of Nursing
    • /
    • v.50 no.1
    • /
    • pp.147-157
    • /
    • 2020
  • Purpose: This descriptive study aimed to identify the menstrual cycle characteristics and premenstrual syndrome (PMS) prevalence in Korean young adult women using the retrospective and prospective Daily Record of Severity of Problems (DRSP). Methods: In the first stage, participants included 151 nursing students studying in a university located in Seoul. Data were collected from April 20 to June 2, 2017, using the questionnaire on menstrual characteristics, pictorial blood assessment chart, and retrospective DRSP. In the second stage, participants included 17 students with PMS, based on the screening conducted in the first stage. Data were collected using the prospective DRSP from May 29 to 2 September 2, 2017. Results: Of the study sample, 104 participants (68.9%) had regular periods. Those with regular periods had 11.97 periods annually with a menstrual cycle of 29.38 days and a period duration of 5.72 days. Fifty-five participants (37.4%) showed menorrhagia. Sixty-four participants (42.4%) were found to have PMS based on their retrospective DRSP. When the ratio of women (52.9%) with PMS shown in the prospective DRSP was used as a positive predictive value, the estimated PMS prevalence was 22.4%. Conclusion: This study provides clinically significant PMS prevalence among Korean young adult women, positive predictive value of the retrospective DRSP, and valid data to basically understand the menstrual cycle characteristics experienced by these women.