• Archives of Plastic Surgery
• /
• v.48 no.5
• /
• pp.559-567
• /
• 2021

The potential to differentiate into different cell lines, added to the easy and cost-effective method of extraction, makes adipose-derived stem cells (ADSCs) an object of interest in lymphedema treatment. Our study's goal was to conduct a comprehensive systematic review of the use of ADSCs in lymphatic tissue engineering and regeneration. On July 23, 2019, using PubMed/MEDLINE, Cochrane Clinical Answers, Cochrane Central Register of Controlled Trials, and Embase databases, we conducted a systematic review of published literature on the use of ADSCs in lymphatic tissue engineering and regeneration. There were no language or time frame limitations, and the following search strategy was applied: ((Adipose stem cell) OR Adipose-derived stem cell)) AND ((Lymphedema) OR Breast Cancer Lymphedema). Only original research manuscripts were included. Fourteen studies fulfilled the inclusion criteria. Eleven studies were experimental (in vitro or in vivo in animals), and only three were clinical. Publications on the topic demonstrated that ADSCs promote lymphangiogenesis, and its effect could be enhanced by modulation of vascular endothelial growth factor-C, interleukin-7, prospero homeobox protein 1, and transforming growth factor-β1. Pilot clinical studies included 11 patients with breast cancer-related lymphedema, and no significant side effects were present at 12-month follow-up. Literature on the use of ADSCs in lymphatic tissue engineering and regeneration demonstrated promising data. Clinical evidence is still in its infancy, but the scientific community agrees that ADSCs can be useful in regenerative lymphangiogenesis. Data collected in this review indicate that unprecedented advances in lymphedema treatment can be anticipated in the upcoming years.

• Journal of Animal Science and Technology
• /
• v.63 no.5
• /
• pp.1064-1075
• /
• 2021

Recently, a high level of dietary crude protein (CP) has become of interest as a possible practice to improve the carcass quality of beef cattle, and its level has been increasing in the field. However, there is little scientific evidence that supports this. This study was conducted to test whether a high dietary CP level would improve growth performance, body metabolism, and carcass traits in Hanwoo beef cattle. A total of 32 Hanwoo finishing beef cattle (18 multiparous cows, six heifers, and eight steers) participated in a 12-weeks feeding trial. Two kinds of total mixed rations were prepared to contain two different CP; 156 g/kg for the control (CON) and 173 g/kg of CP for the treatment (HCP), while maintaining a similar level of metabolizable energy. The experiment was ended when more than half of the steers reached the target body weight (730 kg). Blood was collected at the end of the experiment. After harvesting, the carcass trait was evaluated at the slaughterhouse according to Korean standards. The carcass yield score and grade were also calculated based on revised criteria. Overall, dry matter intake, average daily gain, blood metabolites concentration, and the carcass traits, except for backfat thickness and the yield score, did not differ between the treatments. The HCP had lower backfat thickness than those of CON. There was no difference in the carcass yield grade, but the yield score was higher in the HCP treatment. According to the newly revised carcass grading criteria, both yield score and grade were higher in HCP than in CON. Increasing CP supply decreased the carcass's backfat thickness without altering growth performance and body metabolism, resulting in improved yield score and grade. Therefore, feeding a high CP diet may be beneficial in the farm income, although it may also increase feed cost and nitrogen excretion to the environment.

• Journal of the Korea Convergence Society
• /
• v.12 no.12
• /
• pp.49-57
• /
• 2021

With the advent of the era of the fourth industry, more and more scientific techniques are being used to solve decision-making problems. In particular, big data analysis technology is developing as it becomes easier to collect numerical data. Therefore, in this study, in order to overcome the limitations of qualitatively analyzing investment trends, the association of various products was analyzed using associated analysis techniques. For the experiment, two experimental periods were divided based on the COVID-19 economic crisis, and sales information from individuals, institutions, and foreign investors was collected, and related analysis algorithms were implemented through r software. As a result of the experiment, institutions and foreigners recently invested in the KOSPI and KOSDAQ markets and bought futures and products such as ETF. Individuals purchased ETN and ETF products together, which is presumed to be the result of the recent great interest in sector investment. In addition, after COVID-19, all investors tended to be passive in investing in high-risk products of futures and options. This paper is thought to be a useful reference for product sales and product design in the financial field.

• Agribusiness and Information Management
• /
• v.10 no.1
• /
• pp.1-15
• /
• 2018

Many paddy cultivating farmers in the country are forced to use their limited resources to produce adequate food for their family, leading to the degradation and reduction in potential of these resources. The yield levels of paddy at the farmers' level and in the Front Line Demonstrations (FLDs) conducted in the farmers' fields is not at par with potential yield of the paddy variety. The gap between potential yield of crop variety and yield realized in FLDs refers to Research gap and the yield gap between FLDs and due to farmers' practice refers to Extension gap. The earlier studies conducted in India in general and in Andhra Pradesh in particular highlighted the existence of both research and extension gaps with reference to paddy. It is essential that, the narrowing of both research and extension gaps is not static, but dynamic considering the influence of technological interventions in boosting paddy yields at FLDs level and at farmers' level and also with the improvement of the yield potential of paddy varieties. This calls for integrated and holistic approaches to address these two gaps and with this background, the researcher aimed at this in depth study. The findings revealed that, research gaps are high with reference to weed management and pest management and extension gaps are high with reference to farm mechanization followed by fertilizer management. Reliable source of seed, capital use and frequency of meetings with Scientists or Agricultural Officers significantly influence the extension gaps in paddy. Farmers also prioritized socio-economic and technical constraints and the analysis infers that, it is high time now for the farmers to adopt the planned technological interventions on scientific scale to minimize the extension gaps to the extent possible. As the enabling environment in the State of Andhra Pradesh is highly encouraging for the farmers with relevant policy instruments in the form of subsidized inputs, free power, credit at concessional rates of interest, constructing irrigation projects etc., the adoption of the proposed technological interventions significantly contribute to minimizing both research and extension gaps in paddy cultivation in Kurnool district of Andhra Pradesh.

• Biomolecules & Therapeutics
• /
• v.27 no.3
• /
• pp.265-275
• /
• 2019

Technological advances of mankind, through the development of electrical and communication technologies, have resulted in the exposure to artificial electromagnetic fields (EMF). Technological growth is expected to continue; as such, the amount of EMF exposure will continue to increase steadily. In particular, the use-time of smart phones, that have become a necessity for modern people, is steadily increasing. Social concerns and interest in the impact on the cranial nervous system are increased when considering the area where the mobile phone is used. However, before discussing possible effects of radiofrequency-electromagnetic field (RF-EMF) on the human body, several factors must be investigated about the influence of EMFs at the level of research using in vitro or animal models. Scientific studies on the mechanism of biological effects are also required. It has been found that RF-EMF can induce changes in central nervous system nerve cells, including neuronal cell apoptosis, changes in the function of the nerve myelin and ion channels; furthermore, RF-EMF act as a stress source in living creatures. The possible biological effects of RF-EMF exposure have not yet been proven, and there are insufficient data on biological hazards to provide a clear answer to possible health risks. Therefore, it is necessary to study the biological response to RF-EMF in consideration of the comprehensive exposure with regard to the use of various devices by individuals. In this review, we summarize the possible biological effects of RF-EMF exposure.

• Journal of Information Science Theory and Practice
• /
• v.6 no.4
• /
• pp.6-16
• /
• 2018

This article shows an approach to the study of two fundamental aspects of the prepublication of scientific manuscripts in specialized repositories (arXiv). The first refers to the size of the interaction of "standard papers" in journals appearing in the Web of Science (WoS)-now Clarivate Analytics-and "non-standard papers" (manuscripts appearing in arXiv). Specifically, we analyze the citations found in the WoS to articles in arXiv. The second aspect is how publication in arXiv affects the citation count of authors. The question is whether or not prepublishing in arXiv benefits authors from the point of view of increasing their citations, or rather produces a dispersion, which would diminish the relevance of their publications in evaluation processes. Data have been collected from arXiv, the websites of the journals, Google Scholar, and WoS following a specific ad hoc procedure. The number of citations in journal articles published in WoS to preprints in arXiv is not large. We show that citation counts from regular papers and preprints using different sources (arXiv, the journal's website, WoS) give completely different results. This suggests a rather scattered picture of citations that could distort the citation count of a given article against the author's interest. However, the number of WoS references to arXiv preprints is small, minimizing this potential negative effect.

• Journal of The Korean Association For Science Education
• /
• v.39 no.1
• /
• pp.129-141
• /
• 2019

As the number of minority students such as multicultural, North Korean defectors, and low-income groups increases, more research is needed in science education to help their learning. Due to the various growth backgrounds and learning environments of the underprivileged students, there is a big difference in the individual characteristics of the group rather than the whole group characteristics. In this study, we conducted about 50 hours of science lessons for seven students in the underprivileged class, categorized them by observing and interviewing the characteristics of their science learning. Seven underprivileged students showed five different learning patterns, these are 'I love science', 'I think I know science', 'I want to know science', 'I need to know science', and 'I don't know what I want'. Although the scientific activities they experienced were not all of an excellent educational quality, their interest in science learning has increased with their experience in science activities. It shows the need to provide more abundant science experience and educational opportunities for these minority students who can only experience science learning under the public educational system.

• Journal of Plant Biotechnology
• /
• v.48 no.2
• /
• pp.115-122
• /
• 2021

Aspilia africana (Pers) C.D.Adams, a plant used for centuries in many African countries to treat diseases such as osteoporosis, malaria, tuberculosis, and diabetes, is of great pharmaceutical interest, yet there is limited scientific literature on its germination and growth. This research paper describes the effects of different commercial soils on the germination, growth, and chlorophyll content of A. africana. The germination parameters assessed included final germination percentage (FGP), mean germination time (MGT), and germination index (GI). Shoot length, leaf number, and fresh and dry weights were some of the parameters used to assess A. africana growth. The FGP was low and did not vary significantly; the MGT was 7 ~ 10 days; and the GI was significantly higher in PPS soil at 4.61 ± 0.332 days. Aspilia africana plants in HS:PPS soil showed the best overall growth, producing the highest mean leaf number (18.00 ± 1.129), longest mean shoot length (202.43 ± 13.451 mm), and highest mean fresh and dry weights (7.08 ± 1.061 g and 0.629 ± 0.112 g, respectively). The highest chlorophyll content in leaves of A. africana under HS:PPS conditions suggested a higher photosynthetic potential of plants in this soil. The best growth performance of A. africana in the HS:PPS soil could be attributed to a higher amount of certain mineral nutrients such as nitrogen, potassium, and phosphorus in the HS:PPS soil compared to the other soil categories. It is unclear why the FGP of A. africana was low and we recommend an exclusive study to investigate this further.

• The Journal of the Korea Contents Association
• /
• v.21 no.2
• /
• pp.100-112
• /
• 2021

With the recent growth of the big data technology market, interest in visualization technology has steadily increased over the past few years. Data visualization is currently used in a wide range of disciplines such as information science, computer science, human-computer interaction, statistics, data mining, cartography, and journalism, each with a slightly different meaning. Big data visualization in smart cities that require multidisciplinary research enables an objective and scientific approach to developing user-centered smart city services and related policies. In particular, spatial-based data visualization enables efficient collaboration of various stakeholders through visualization data in the process of establishing city policy. In this paper, a user-centered spatial big data visualization expression request method was derived by examining the spatial-based big data visualization expression process and principle from the viewpoint of effective information delivery, not just a visualization tool.

• Journal of The Korean Association of Information Education
• /
• v.24 no.6
• /
• pp.539-550
• /
• 2020

This study establishes the scientific basis for the use of digital learning materials through the education-neurological research method and derives implications for education based on education-neurological understandings. The main findings of the education-neurological analysis of digital learning materials are as follows: First, various sensory stimuli go through multiple sensory neurons and deep sections of the upper sphere and make possible the cooperative processing of information. Second, indirect experience from digital learning materials helps students understand the learning contents vividly through the mirror neuron system. Third, positive emotions originating from digital learning materials promote functions of dopamine, the reticular activating system, frontal-striatal circuit, cerebrum cortex. Based on the findings, the study suggests the following educational implications. First of all, when selecting digital learning materials, teachers should consider expression forms, learning contents, the flow of classes, and the adverse effects of digital learning materials. Next, it is effective to utilize digital learning materials in the lecture for provoking curiosity and enjoyment, maintaining interest and effort, and reviewing what students learned.