• Journal of Ginseng Research
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• v.16 no.3
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• pp.228-234
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• 1992

There has been general tendency to explain the traditional ginseng efficacy through the pharmacological and biochemical activities of ginsenosides. However, when we analyze the pharmacological and biological data on ginseng reported yet, we can easily arrive at the conclsion that most of the data on pharmacological and biological activities must have been obtained using impure ginsenoside samples, which should contain some non-saponin constituents as impurities. Based on the above back-ground, the non-saponin constituents of ginseng were studied in our laboratory. Phenolic substances including Maltol, Vanillic Acid, Salicylic Acid, Ferrulic Acid and Caffeic acid and impure ginsenoside samples were found to show strong antioxidant and anti-fatigue activities, while pure ginsenosides were devoid of the activities. Maltol, one of antioxidant components In Korean red ginseng drew a special interest due to its very low pro-oxidant activity. The antioxidant activity of ginseng may be considered as scientific basis for the antiageing activity which was described in traditional medicinal material book as "long-term medication of ginseng will improve bio-efficiency and extend life-span" The lignin components, another non-saponin consitutents, isolated from ginseng extract In our laboratory may eplain the hepato-protective activity of ginseng which has been repeatedly rtaimed as one of the efficacies of ginsenosides. The P-carboline alkaloids isolated in our laboratory as one of the non-saponin constituents of ginseng may play some pharmacological activities which should also be investigated. Present paper will include chemistry and biochemical aspects of the non-saponin constituents of ginseng with special interests for the explanation of traditional ginseng efficacy on modern scientific basis.fic basis.

• Journal of Korean Society for Quality Management
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• v.50 no.3
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• pp.373-386
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• 2022

Purpose: This study proposes the application of Six Sigma management innovation method for more systematically enhanced execution of Quality by Design (QbD) activities. QbD requires a deeper understanding of the product and process at the design and development stage of the drug, and it is very important to ensure that no fault is fundamentally generated through thorough process control. Methods: Analyzing the background and specific procedures of quality improvement based on the drug design basis, and analyzing the key contents of each step, we have differentated and common points from the 6 Sigma methodology. We propose a new model of Six Sigma management innovation method suitable for pharmaceutical industry. Results: Regulatory agencies are demanding results from statistical analysis as a scientific basis in developing medicines to treat human life through quality improvement activities based on drug design. By utilizing the education system to improve the statistical analysis capacity in the Six Sigma activities and operating the 6 Sigma Belt system in conjunction, it helped systematically strengthen the execution power of quality improvement activities based on pharmaceutical design based on the members of the pharmaceutical industry. Conclusion: By using QbD Six Sigma, which combines quality enhancement based on pharmaceutical design basis and Six Sigma methodology suitable for pharmaceutical industry, it is possible to obtain satisfactory results both by pharmaceutical companies and regulators by using appropriate statistical analysis methods for preparing scientific evidence data required by regulatory.

• Journal of The Korean Association For Science Education
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• v.25 no.5
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• pp.563-570
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• 2005

This study investigated the relationships among middle school students' understanding about the nature of scientific knowledge, conceptual understanding, and learning strategies. Grade 7 students (N=162) in Incheon completed the nature of scientific knowledge scales (NSKS) and a learning strategy questionnaire. After learning density by way of a CAl program, a conception test was administered. Results indicated that students' conceptual understanding and both deep and surface learning strategies were significantly correlated to their understanding about the nature of scientific knowledge. A cluster analysis was used to classify students on the basis of their deep and surface learning strategies. Three clusters of students with distinctive learning strategy patterns were found; high deep-low surface strategy (cluster 1), low deep-high surface strategy (cluster 2), and high deep-high surface strategy (cluster 3). One-way ANOVA results revealed that the scores of cluster 3 were significantly higher than those of the others in the NSKS and the conception test. Additionally, cluster 1 also performed better than cluster 2 in the conception test. Lastly, educational implications were discussed.

• Journal of the Korean earth science society
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• v.44 no.6
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• pp.533-539
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• 2023

This article reviews a few academic discussions in our geological society. The author presents his opinion on the discussions regarding the ages of the Okcheon Group, Myogog Formation, and hominid footprints of the Jeju Island, as well as on the inaccurate reportage in mass media. The academia advances via healthy debates and discussions. The arguments for and against Darwin's "Origin of Species" and scientific debates regarding Wegener's "Continental Drift Hypothesis" are well known. In academic debates or discussions, authority should not be involved in any form. Academic research should be conducted based on scientific principles and evidence-free of personal preferences or other nonacademic factors. Opponents should challenge with scientific approaches, suggesting alternatives based on science. Opposition without scientific basis is not productive in conducting academic research in search of scientific truth. Often, the news media delivers inaccurate information to the public-intentionally or unintentionally. There must be a mechanism to immediately identify and rectify inaccurate, false, or fake information for the benefit of the public and the credibility of the news media.

• Journal of the Korean earth science society
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• v.29 no.2
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• pp.204-217
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• 2008

This study analyzed the inquiry activities appearing in the astronomy sections of elementary, middle and highschool level science textbooks according to the five essential features of inquiry in the classroom as proposed by the National Science Education Standards (NRC, 2000), and SAPA (Science-A Process Approach). On the basis of this analysis, it is clear that the science textbook inquiry activities released the limitation to meet the goal of science education, namely scientific literacy, as it has been laid out by the 7th Science Educational Curriculum. This study revealed that the features of scientific inquiry which are most frequently used in the astronomy sections of science textbooks are 'data collection' and 'form explanation', whereas the features of 'oriented-question', 'evaluate explanations' and 'communicate and justify' rarely appeared. The analysis of inquiry activities by SAPA showed that the basic inquiry skills of 'observing', 'communicating' and 'manipulating materials' were used with increasing frequency according to grade level, and the integrated skills of 'investigating', 'creating models', 'interpreting data' and 'experimenting' were more emphasized in the textbooks. Therefore, it is suggested that students be provided with more opportunities to experience all the features of scientific inquiry and scientific processes as envisioned by the 7th Science Educational Curriculum in order to achieve the stated goal of scientific literacy. Science educators should be required to develop new lesson modules which will allow students to experience authentic scientific inquiry. It is crucial for science teachers to reflect upon and develop their understanding and teaching strategies regarding scientific inquiry through professional development programs in teacher education.

• Development and Reproduction
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• v.15 no.1
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• pp.71-76
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• 2011

Due to its role in maintaining the health of scientific societies, research ethics (or integrity) is notably receiving attention by academia, governments and even individuals who are not engaged in scientific researches. In this paper, I will introduce some valuable papers dealt with plagiarism as a representative research misconduct. In general, researcher's results that will soon be published must meet the crucial scientific criteria: originality, accuracy, reproducibility, precision and research ethics. The definition of plagiarism is "appropriation of another person's ideas, processes, results, or words without giving appropriate credit." Compared to fabrication and falcification, plagiarism is often considered as a minor misconduct. With intentionality, however, plagiarism can be corresponding to 'theft of intellectual product'. The context of plagiarism is not restricted to the stage of publication. It can be extended to prior stages of proposing (i.e. preparing the research proposal) and performing (executing the research), and reviewing (writing the review papers). Duplicate publication is regarded as a self-plagiarism in broad interpretation of plagiarism. To avoid dangers of plagiarism, earnest efforts from all members of scientific community are needed. First of all, researchers should keep 'transparency' and 'integrity' in their scientific works. Editorial board members and reviewers should keep fairness and well-deserved qualification. Government and research foundations must be willing to provide sufficient financial and policy support to the scientific societies; Up-graded editorial services, making good use of plagiarism detection tools, and thorough instruction on how to write a honest scientific paper will contribute to building up a healthy basis for scientific communities.

• Journal of Korean Elementary Science Education
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• v.32 no.4
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• pp.503-514
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• 2013

The purpose of this study is to investigate the perception on fossil in elementary science 'Earth and Space' domain for elementary school students. For this purpose, the fossil perception inventory was developed. And the fossil perception was examined for random sampling of 5th and 6th grade 635 students. As a result, students chosen incorrect answer of the average 30.8% for questions of fossil perception. Over the average rate of incorrect answers in 20 questions were 8 questions(3 in the definitions for fossil, 2 in the creation of fossil, 2 in the fossil, sedimentary, stratum, 1 in the understanding for fossil). When the results were analyzed by residence and grade, there were significant differences in 7 questions between students in urban and rural areas, and between 5th and 6th students, there were important contrasts in 4 questions. The data that understanding of elementary students fossil can be provided for form the basis planning the teaching method to correct student's scientific concepts in elementary school. The results are also contributed to find an effective way for modify misconceptions of fossils to the scientific concepts.

• Structural Engineering and Mechanics
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• v.64 no.3
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• pp.311-321
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• 2017

This paper presents the details of analytical studies carried out towards the prediction of flexural capacity and load-deflection behaviour of Laced Steel-Concrete Composite (LSCC) beams. Analytical expressions for flexural capacity of the beams are derived in accordance with the basic principles of conventional Reinforced Concrete (RC) beams, but incorporated with relevant modifications to account for the composite nature of the cross-section. The ultimate flexural capacity of the two LSCC beams predicted using the derived expressions is found to be approximately 20% lower than those obtained due to measurement from experiments. Further to these, two simple methods are also proposed on the basis of unit load method and equivalent steel beam method to determine the non-linear load-deflection response of the LSCC beams for monotonic loading. Upon validation of the proposed methods by comparing the predicted responses with those of experiments and finite element analysis, it is found that the methods are useful to find nonlinear response of such composite beams.

• Science of Emotion and Sensibility
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• v.6 no.4
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• pp.51-60
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• 2003

The objectives of this study are to identify sensibility factors involved in evaluating casual T-shirts design, and to analyze its effect on consumer sensibility, The consumer sensibility in evaluating casual T-shirts design consisted of three sub-dimensions, those are, 'stylishness', 'commonness', and 'activeness'. This study revealed that design factors of casual t-shirts, such as collar style, detail, position of logotype, size of logotype and demographic trait, have significant impact on the consumer sensibility. A few of scientific design methods were derived from the result of this study. A series of effective casual T-shirt prototypes, which was designed using these scientific methods, was presented to demonstrate how to achieve desired consumer impression. The derived scientific methods are expected to be used for specific valuation basis in design planning.

• Ocean and Polar Research
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• v.41 no.2
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• pp.107-120
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• 2019

The frequency analysis of scientific terms using bibliographic information is a simple concept, but as relevant data become more widespread, manual analysis of all data is practically impossible or only possible to a very limited extent. In addition, as the scale of oceanographic research has expanded to become much more comprehensive and widespread, the allocation of research resources on various topics has become an important issue. In this study, the frequency analysis of scientific terms was performed using text mining. The data used in the analysis is a general-purpose scholarship database, totaling 2,878 articles. Hypoxia, which is an important issue in the marine environment, was selected as a research field and the frequencies of related words were analyzed. The most frequently used words were 'Organic matter', 'Bottom water', and 'Dead zone' and specific areas showed high frequency. The results of this research can be used as a basis for the allocation of research resources to the frequency of use of related terms in specific fields when planning a large research project represented by single word.