• Title/Summary/Keyword: science laboratory practices

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Flavonols, Flavones, Flavanoues and Human Health: Epidemiological Evidence

  • Graf Brigitte A.;Milbury Paul E.;Blumberg Jeffrey B.
    • Proceedings of the Korean Society of Food Science and Nutrition Conference
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    • 2004.11a
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    • pp.24-36
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    • 2004
  • Polyphenolic flavonoids are among a wide variety of phytochemicals present in the human diet. Basic research, animal model, and human studies suggest flavonoid intake may reduce the risk of several age-related chronic diseases. The vast number of flavonoids and mixtures of their subclasses, including flavonols, flavones and flavanones, and the variety of agricultural practices that affect their concentration in foods have presented a challenge to the development of adequate food composition databases for these com-pounds. Nonetheless, dietary assessments have been applied to cohort and case-control epidemiological studies and several reveal an inverse association with risk of some forms of cancer, cardiovascular disease, and other chronic conditions. Those observational studies that have examined these relationships with regard to flavonols, flavones, and flavanones are reviewed. The requirement for caution in interpreting these studies is discussed with regard to the limited information available on the bioavailability and biotransformation of these flavonoids. As the totality of the available evidence on these flavonoids suggests a role in the prevention of cancer and cardiovascular disease, further research is warranted, particularly in controlled clinical trials.

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Study on Legal Issues and Scope of Medical Technologist's Practice (임상병리사 업무 범위와 법률적 고찰)

  • Shim, Moon-Jung;Koo, Bon-Kyeong;Park, Chang-Eun
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.2
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    • pp.55-68
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    • 2017
  • In recent years, medical practice has seen a drastic change due to the rapid, exponential expansion of scientific and medical technologies. Specially, the role of medical technologists (also known as medical laboratory scientists and/or clinical laboratory scientists) are increasing in the development of science of medical technology. As such, their responsibility has also been increasing. Therefore, given their highly specialized knowledge and skills, they are not regarded solely as doctor's assistants. Their independence and deeper specialization have been increasing, as they perform medial practices under the guidance of doctors or dentists pursuant to the "Act on Medical Service Technologists." From a legal point of view, medical guidance and scope of work were examined. As a conclusion, the definition of doctor's superintendency on the "Act on Medical Service Technologists" is required, and the qualification for the Korean license examination and their roles should be stated clearly. Moreover, communications among health professions regarding the roles of medical technologists are necessary to further facilitate clarification of their role. There is a need for independent legislation to expand the field of medical technologists and to strengthen their professionalism.

Physicochemical and histopathological parameters of broilers with dorsal cranial myopathy

  • Ana Clara Longhi Pavanello;Fernanda Jessica Mendonca;Thalita Evani Silva Oliveira;Guilherme Bau Torezan;Giovana Wingeter Di Santis;Adriana Lourenco Soares
    • Animal Bioscience
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    • v.36 no.6
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    • pp.953-961
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    • 2023
  • Objective: This study aimed to investigate the effect of dorsal cranial myopathy (DCM) on chicken meat quality. Methods: Sixty-six Ross 308 AP broilers, 47 days old, of both sexes, weighing about 3.51 kg, were slaughtered according to standard industrial practices, and evaluated for meat color, pH, chemical composition, collagen content, fatty acid profile, and histopathological parameters. Comparisons between normal and DCM-affected meat were performed using Student's t-test at the 5% significance level. Results: Histological analysis of muscle tissues affected by DCM showed myofiber degeneration, proliferation of inflammatory cells, fibroplasia, and necrosis with fibrosis. DCM samples had lower protein content and higher moisture, ash, insoluble collagen, total collagen, and pH. DCM-affected meat was redder and more yellowish. There were no differences in lipid or soluble collagen contents between groups. DCM-affected meat had higher percentages of arachidonic acid (C20:4n-6) and eicosapentaenoic acid (C20:5n-3). Conclusion: This study revealed that DCM-affected meat exhibits considerable changes in quality parameters.

Increasing Production in Korean Shrimp Farms with White-Spot Syndrome Virus PCR-Negative Brood Stock

  • Seok, Seung-Hyeok;Baek, Min-Won;Lee, Hui-Young;Kim, Dong-Jae;Chun, Myung-Sun;Kim, Jong-Sheek;Chang, Se-Ok;Park, Jae-Hak
    • Journal of Microbiology and Biotechnology
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    • v.17 no.3
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    • pp.511-515
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    • 2007
  • White-spot syndrome virus (WSSV) is a devastating, infectious virus affecting shrimp. Although sensitive techniques involving PCR have been developed to assist farmers in screening shrimp (brood stock) for WSSV prior to stocking ponds, such practices have not yet been applied in Korea. Despite the rationality of implementing screening, there has been some doubt as to whether the stocking of WSSV-PCR-negative fly epidemiologically decreases white-spot disease outbreaks. Here, we report a retrospective analysis of data from shrimp farms in the western coast of Korea where WSSV-PCR-negative brood stocks were used to stock rearing ponds. A total of 366 shrimp from Heuksan Island were sampled for WSSV with PCR. Of the tested shrimp, 7.2% (28 brood stocks) were identified as WSSV positive; only WSSV-PCR-negative shrimp were used for brood stocks. Total unit production (final shrimp production/ the area of the ponds) was higher, at 1.96, in ponds where WSSV-PCR-negative shrimp were used, as compared with 1.02 in other ponds in Korea in 2004. This retrospective analysis of WSSV in Korea may be useful to the shrimp aquaculture industry, suggesting a testable hypothesis that may contribute to the eventual control of WSSV outbreaks.

Phenotypic and Genotypic Detection of Metallo-β-Lactamase Producing Pseudomonas aeruginosa

  • Yang, Byoung-Seon;Hong, Keun-Seok;Jung, Seung-Bong;Kwon, Young-Hoon;Jeong, Jong-Yoon;Lee, Min-Joo;Lee, Hye-In;Park, Mi-Seon;Choi, Seung-Gu
    • Korean Journal of Clinical Laboratory Science
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    • v.44 no.2
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    • pp.81-85
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    • 2012
  • This study was undertaken to evaluate phenotypic and genotypic methods for detection of Metallo-Beta-Lactamases (MBLs) among nosocomial Pseudomonas aeruginosa. Of the 50 P. aeruginosa isolates from clinical specimens, 20 were evaluated for carbapenem resistance and screened for MBL by double-disk synergy test and combined-disk test. Nineteen strains (95%) were found to be MBL producers among the 20 P. aeruginosa. MBL positives were further confirmed by Polymerase Chain Reaction (PCR). For the IMP and VIM types of MBLs, PCR analysis was performed on 19 of the 20, and 10 were positive for VIM MBL type. This study reports the validation of a simple and accurate MBL detection method that can be easily incorporated into the daily routine of a clinical laboratory. Early detection of MBL-carrying organisms, including those with susceptibility to carbapenems, is of paramount clinical importance, as it allows rapid initiation of strict infection control practices as well as therapeutic guidance for confirmed infection.Key Words : Hepatitis A virus (HAV), Anti-HAV, Hospital workers, Prevalence, Vaccination

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Experimental investigation on bolted rock mass under static-dynamic coupled loading

  • Qiu, Pengqi;Wang, Jun;Ning, Jianguo;Shi, Xinshuai;Hu, Shanchao
    • Geomechanics and Engineering
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    • v.29 no.2
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    • pp.99-111
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    • 2022
  • Instability of bolted rock mass has been a major hazard in the underground coal mining industry for decades. Developing effective support guidelines requires understanding of complex bolted rock mass failure mechanisms. In this study, the dynamic failure behavior, mechanical behavior, and energy evolution of a laboratory-scale bolted specimens is studied by conducting laboratory static-dynamic coupled loading tests. The results showed that: (1) Under static-dynamic coupled loading, the stress-strain curve of the bolted rock mass has a significant impact velocity (strain rate) correlation, and the stress-strain curve shows rebound characteristics after the peak; (2) There is a critical strain rate in a rock mass under static-dynamic coupled loading, and it decreases exponentially with increasing pre-static load level. Bolting can significantly improve the critical strain rate of a rock mass; (3) Compared with a no-bolt rock mass, the dissipation energy ratio of the bolted rock mass decreases exponentially with increasing pre-static load level, the ultimate dynamic impact energy and dissipation energy of the bolted rock mass increase significantly, and the increasing index of the ratio of dissipation energy increases linearly with the pre-static load; (4) Based on laboratory testing and on-site microseismic and stress monitoring, a design method is proposed for a roadway bolt support against dynamic load disturbance, which provides guidance for the design of deep underground roadway anchorage supports. The research results provide new ideas for explaining the failure behavior of anchorage supports and adopting reasonable design and construction practices.

Study of educational management on performance of scholar in nano/micro-level composite

  • Chunhong Zhang;Yun Liu;Yong Zhang;Artin Ketabdar;H.B. Xiang
    • Advances in nano research
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    • v.16 no.6
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    • pp.615-622
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    • 2024
  • This study investigates the impact of educational management on the performance of scholars in the field of nano/micro-level composites. The objective is to understand how effective management strategies can enhance the academic achievements and research outcomes of students specializing in this advanced area of materials science. Through a combination of qualitative and quantitative methodologies, data was collected from various educational institutions renowned for their programs in nano/micro-level composites. Our results indicate that tailored educational management practices significantly improve student performance. Key strategies identified include personalized mentorship programs, interdisciplinary collaboration opportunities, and access to state-of-the-art laboratory facilities. Institutions that implemented these practices observed a marked increase in the quality and quantity of research outputs, higher student satisfaction rates, and improved post-graduation employment prospects in relevant industries. Furthermore, the study highlights the importance of continuous professional development for educators to stay abreast of the latest advancements in nano/micro-level composites. By fostering an environment of innovation and support, educational management can play a crucial role in shaping the next generation of researchers and professionals in this cutting-edge field. These findings underscore the necessity of strategic educational management in optimizing the academic and professional trajectories of scholars in nano/micro-level composites, ultimately contributing to advancements in technology and industry applications.

Potential soil loss evaluation using the RUSLE/RUSLE-runoff models in Wadi Saida watershed (N-W Algeria)

  • Cherif, Kessar;Yahia, Nasrallah;Bilal, Bilssag
    • Advances in environmental research
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    • v.9 no.4
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    • pp.251-273
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    • 2020
  • Soil degradation has become a major worldwide environmental problem, particularly in arid and semi-arid climate zones due to irregular rainfall and the intensity of storms that frequently generate heavy flooding. The main objective of this study is the use of geographic information system and remote sensing techniques to quantify and to map the soil losses in the Wadi Saida watershed (624 ㎢) through the revised universal soil loss equation model and a proposed model based on the surface erosive runoff. The results Analysis revealed that the Wadi Saida watershed showed moderate to moderately high soil loss, between 0 and 1000 t/㎢/year. In the northern part of the basin in the region of Sidi Boubkeur and the mountains of Daia; which are characterized by steep slopes, values can reach up to 3000 t/㎢/year. The two models in comparison showed a good correlation with R = 0.95 and RMSE = 0.43; the use of the erosive surface runoff parameter is effective to estimate the rate of soil loss in the watersheds. The problem of soil erosion requires serious interventions, particularly in basins with disturbances and aggressive climatic parameters. Good agricultural practices and forest preservation areas play an important role in soil conservation.

Infection Control in Pulmonary Function Laboratories in Domestic Hospitals (국내 의료기관의 폐기능검사실에서 감염관리 실태조사)

  • Nan-Hee LEE;Suhng Wook KIM
    • Korean Journal of Clinical Laboratory Science
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    • v.55 no.3
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    • pp.143-150
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    • 2023
  • The global outbreak of COVID-19 has underscored the pressing need for robust infection control practices in pulmonary function laboratories (PFL). However, the existing guidelines and regulatory frameworks provided by relevant authorities in the country have revealed certain deficiencies in effectively addressing this significant public health crisis. This study surveyed the infection control regulations, disposable item usage, ventilation facilities, spatial separation, and the configuration of entrance doors in 51 domestic hospital facilities from Oct 1, 2021, to Nov 2, 2021. The survey findings revealed that while there was a relatively satisfactory adherence to airborne, droplet, and contact precautions with adequate awareness and utilization of personal protective equipment, the environmental disinfection practices exhibited a suboptimal performance rate of 39.22% per patient. Depending on the specific survey domains, substantial variations were observed in the utilization of disposable items (81.05%), ventilation systems (45.75%), dedicated testing spaces (80.39%), separation of administrative areas (15.69%), and the installation of automated doors (19.61%). This study not only highlights the paramount importance of infection control in PFLs within domestic medical institutions but also provides foundational data for developing and enhancing standardized guidelines that align with international benchmarks for infection control in these settings.

A Mathematics Teacher's Reflective Practice as a Process of Professional Development (전문성 신장 과정으로서의 한 수학교사의 성찰적 실천)

  • Kim, Dong-Won
    • Communications of Mathematical Education
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    • v.23 no.3
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    • pp.735-760
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    • 2009
  • Most of every teachers' life is occupied with his or her instruction, and a classroom is a laboratory for mutual development between teacher and students also. Namely, a teacher's professionalism can be enhanced by circulations of continual reflection, experiment, verification in the laboratory. Professional development is pursued primarily through teachers' reflective practices, especially instruction practices which is grounded on $Sch\ddot{o}n's$ epistemology of practices. And a thorough penetration about situations or realities and an exact understanding about students that are now being faced are foundations of reflective practices. In this study, at first, we explored the implications of earlier studies for discussing a teacher's practice. We could found two essential consequences through reviewing existing studies about classroom and instructions. One is a calling upon transition of perspectives about instruction, and the other is a suggestion of necessity of a teachers' reflective practices. Subsequently, we will talking about an instance of a middle school mathematics teacher's practices. We observed her instructions for a year. She has created her own practical knowledges through circulation of reflection and practices over the years. In her classroom, there were three mutual interaction structures included in a rich expressive environments. The first one is students' thinking and justifying in their seats. The second is a student's explaining at his or her feet. The last is a student's coming out to solve and explain problem. The main substances of her practical know ledges are creating of interaction structures and facilitating students' spontaneous changes. And the endeavor and experiment for diagnosing trouble and finding alternative when she came across an obstacles are also main elements of her practical knowledges Now, we can interpret her process of creating practical knowledge as a process of self-directed professional development when the fact that reflection and practices are the kernel of a teacher's professional development is taken into account.

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