• Journal of the Korean earth science society
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• v.38 no.4
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• pp.303-320
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• 2017

Purpose of this study is understanding of group modeling process focusing on constraints with geological field trip applied on social-construction of scientific model. This study was carried out on 12 students of 3 groups who participate in the study 'S' gifted education center. Students were conducted to theme of 'How was formation of Mt. Gwanak?' on 2 field trip classes and 3 modeling classes. Semi-structured interviews, all discourse of field trip and modeling classes, records of personal and group activity were analyzed to constraints based on theoretical background proposed by Nersessian (2008). Results as follows. First, sources of constraints are scientific knowledge, contents observed by students during field trips and additional materials things to be explained by model during modeling class with geological field trip applied on social-construction of scientific model. Second, there are 3 types of constraints to affect making group modeling. It is that shared constraint which used commonly by all the group members. It called selected constraint that used during the initial modeling and later were reflected on for use in the group modeling. And it is that generated constraints, which were not in the initial modeling but were used later in the group modeling. This study suggests that not only the constraints can help to understand of making group model through how they used but also show that example of learning with geological field trip on social-construction of scientific model to contribute school science.

• Journal of The Korean Association For Science Education
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• v.16 no.4
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• pp.340-350
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• 1996

Knowledge is composed through the interaction between the concept structure already held by students and their experience, and learning can be said to be the active process of solving the cognitive conflict caused by this interaction. Therefore, this study consists in showing the effective learning method and finding out the elements which the teacher has to own, through examining several forms of pre-conception or mis-conception of the inertia, the force-equilibrium, the action and reaction, the heat, and the electric current, and then finding out their solution and studying student's change in science concepts. For this study, the types of concept on the five above-mentioned materials which students have were examined through the concept-classifying question paper, and the classes to which the class mode for the change of concepts applied, were practised in each different classroom by each different instructor - a professor, a scientist, a teacher, and two students, respectively. And the effect of the teaching strategy based on these classes, and each different instructor' influence on the change of concept in students. were examined. The result of my study is as follows; 1. Students have various types of pre-conception which are different from science concept, and these types of pre-conception tend to last even after learning in class. 2. The thoughts on the correct science concept of the high school third-grade students who learned the physics in the traditional teaching method, and the second grade students who don't learn the physics yet, were nearly equal those of the second grade students by receiving the physics class through the cognitive conflict course were greatly changed especially that students showed the distinct change on mechanics and electric current. 3. Students didn't show the remarkable change of the science concept on the five materials in the four kinds of experimental classes by each different instructor but in the part of mechanics, there was the distinct change between the class by professor and those by the students. This was due to the difference of the authority and the attitude of the concept demonstrator. 1) The authority, the kind attitude, and the responsibility of the expert played an important role in the correct concept-formation of mechanics part - especially in the case of the mis-conception caused by the intuitive belief. 2) In the class by instructor with the democratic teaching method, the change of concept took place more easily, because in his class students could discuss the subject freely, so that they might experience the thought course to give them the confidence on the science concept.

• Animal Bioscience
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• v.37 no.4
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• pp.609-621
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• 2024

Objective: Hair follicle stem cells (HFSCs) differentiation is a critical physiological progress in skin hair follicle (HF) formation. Goat HFSCs differentiation is one of the essential processes of superior-quality brush hair (SQBH) synthesis. However, knowledge regarding the functions and roles of miR-133a-3p and miR-145-5p in differentiated goat HFSCs is limited. Methods: To examine the significance of chi-miR-133a-3p and chi-miR-145-5p in differentiated HFSCs, overexpression and knockdown experiments of miR-133a-3p and miR-145-5p (Mimics and Inhibitors) separately or combined were performed. NANOG, SOX9, and stem cell differentiated markers (β-catenin, C-myc, Keratin 6 [KRT6]) expression levels were detected and analyzed by using real-time quantitative polymerase chain reaction, western blotting, and immunofluorescence assays in differentiated goat HFSCs. Results: miR-133a-3p and miR-145-5p inhibit NANOG (a gene recognized in keeping and maintaining the totipotency of embryonic stem cells) expression and promote SOX9 (an important stem cell transcription factor) expression in differentiated stem cells. Functional studies showed that miR-133a-3p and miR-145-5p individually or together overexpression can facilitate goat HFSCs differentiation, whereas suppressing miR-133a-3p and miR-145-5p or both inhibiting can inhibit goat HFSCs differentiation. Conclusion: These findings could more completely explain the modulatory function of miR-133a-3p and miR-145-5p in goat HFSCs growth, which also provide more understandings for further investigating goat hair follicle development.

• Journal of Ginseng Research
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• v.42 no.4
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• pp.504-511
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• 2018

Background: The biological activities of ginseng saponins (ginsenosides) are associated with type, number, and position of sugar moieties linked to aglycone skeletons. Deglycosylated minor ginsenosides are known to be more biologically active than major ginsenosides. Accordingly, the deglycosylation of major ginsenosides can provide the multibioactive effects of ginsenosides. The purpose of this study was to transform ginsenoside Rb2, one of the protopanaxadiol-type major ginsenosides, into minor ginsenosides using ${\beta}$-glycosidase (BG-1) purified from Armillaria mellea mycelium. Methods: Ginsenoside Rb2 was hydrolyzed by using BG-1; the hydrolytic properties of Rb2 by BG-1 were also characterized. In addition, the influence of reaction conditions such as reaction time, pH, and temperature, and transformation pathways of Rb2, Rd, F2, compound O (C-O), and C-Y by treatment with BG-1 were investigated. Results: BG-1 first hydrolyzes 3-O-outer ${\beta}$-$\text\tiny{D}$-glucoside of Rb2, then 3-O-${\beta}$-$\text\tiny{D}$-glucoside of C-O into C-Y. C-Y was gradually converted into C-K with a prolonged reaction time, but the pathway of Rb2 ${\rightarrow}$ Rd ${\rightarrow}$ F2 ${\rightarrow}$ C-K was not observed. The optimum reaction conditions for C-Y and C-K formation from Rb2 by BG-1 were pH 4.0-4.5, temperature $45-60^{\circ}C$, and reaction time 72-96 h. Conclusion: ${\beta}$-Glycosidase purified from A. mellea mycelium can be efficiently used to transform Rb2 into C-Y and C-K. To our best knowledge, this is the first result of transformation from Rb2 into C-Y and C-K by basidiomycete mushroom enzyme.

• Journal of the Korea Society of Computer and Information
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• v.21 no.10
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• pp.175-182
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• 2016

In the 21st century knowledge and information society, Electronic Contracts made with the intention of electronic computer information networks are emerging as a new legal problem which can not be solved in the conventional legal system governing contracts. In other words, the indicator's decision determines the effect and formation of the contracts in the face-to-face or written contracts but electronic decision through computer information network is established the working process of electronic signals-electronic contracts are not only difficult to separate the decision-making process but questioned to be solved by the theory of the general legal action. Ministry of Transportation is scheduled to introduce real estate sales and lease contract using a variety of electronic devices such as computer, tablet PC, smart phones and so on without a paper contract. This system is conducted to global expansion of Seoul in demonstration zone on May 8, 2016 and will be implemented nationwide in the second half of 2017. Electronics contract Real estate has some benefits because made by linking electronic contract system and the electronic registration system - the economic effects discounts on various kinds of fees, the prevention from real estate fraud beforehand and the solution to the complexity of the process the seller and the buyer visits The Real estate agency. However, it has some problem- the disorder in the real estate contract market, the occurrence of the real estate agency accident and the author of the electronic real estate contracts have limited only to realtor. In this paper, I suggest the activation plan to search for establishment and effect of electronic contracts and declaration of intention in electronic depending on the Electronic Contract Real Estate system.

• The Korean Journal of Malacology
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• v.28 no.3
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• pp.277-291
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• 2012

Aquaculture is challenged by a number of constraints with future efforts towards sustainable production. Global climate change has a potential damage to the sustainability by changing environmental surroundings unfavorably. The damaging parameters identified are water temperature, sea level, surface physical energy, precipitation, solar radiation, ocean acidification, and so on. Of them, temperature, mostly temperature elevation, occupies significant concern among marine ecologists and aquaculturists. Ocean acidification particularly draws shellfish aquaculturists' attention as it alters the marine chemistry, shifting the equilibrium towards more dissolved CO2 and hydrogen ions ($H^+$) and thus influencing signaling pathways on shell formation, immune system, and other biological processes. Temperature elevation by climate change is of double-sidedness: it can be an opportunistic parameter besides being a generally known damaging parameter in aquaculture. It can provide better environments for faster and longer growth for aquaculture species. It is also somehow advantageous for alleviation of aquaculture expansion pressure in a given location by opening a gate for new species and aquaculture zone expansion northward in the northern hemisphere, otherwise unavailable due to temperature limit. But in the science of climate change, the ways of influence on aquaculture are complex and ambiguous, and hence are still hard to identify and quantify. At the same time considerable parts of our knowledge on climate change effects on aquaculture are from the estimates from data of fisheries and agriculture. The consequences may be different from what they really are, particularly in the temperature region. In reality, bivalves and tunicates hung or caged in the longline system are often exposed to temperatures higher than those they encounter in nature, locally driving the farmed shellfish into an upper tolerable temperature extreme. We review recent climate change and following environment changes which can be factors or potential factors affecting shellfish aquaculture production in the temperate region.

• Korean Journal of Veterinary Research
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• v.50 no.2
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• pp.139-143
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• 2010

A 2-month-old male Jeju native black calf with respiratory distress was died and requested to the Veterinary Pathology Laboratory of Jeju National University for diagnosis. Grossly, lungs were focally attached to the pleura and heart with fibrin. Purple red sublobar consolidations were distributed in both apical and cardiac lobes of lungs. Histopathologically, diffuse severe bronchointerstitial pneumonia characterized by multifocal necrotizing bronchiolitis, formation of numerous multinucleated syncytial cells in bronchiolar and alveolar lumens, and diffuse alveolar wall thickening were observed in lungs. Eosinophilic intracytoplasmic inclusions were observed in bronchiolar epithelial cells and syncytial cells. According to reverse transcriptase polymerase chain reaction (RT-PCR), bovine respiratory syncytial virus (BRSV) was detected in the lung of calf. Based on the histopathologic findings and RT-PCR, this calf was diagnosed as BRSV infection. In our best knowledge, this is the first case of BRSV infection in Jeju native black calf.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.08a
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• pp.281-281
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• 2010

Very low refractive index (<1.4) materials have been proved to be the key factor improving the performance of various optical components, such as reflectors, filters, photonic crystals, LEDs, and solar cell. Highly porous SiO2 are logically designed for ultralow refractive index materials because of the direct relation between porosity and index of refraction. Among them, ordered macroporous SiO2 is of potential material since their theoretically low refractive index ~1.10. However, in the conventional synthesis of ordered macroporous SiO2, the time required for the crystallization of organic nanoparticles, such as polystyrene (PS), from colloidal solution into well ordered template is typical long (several days for 1 cm substrate) due to the low interaction between particles and particle - substrate. In this study, polystyrene - polyacrylic acid (PS-AA) nanoparticles synthesized by miniemulsion polymerization method have hydrophilic polyacrylic acid tails on the surface of particles which increase the interaction between particle and with substrate giving rise to the formation of PS-AA film by simply spin - coating method. Less ordered with controlled thickness films of PS-AA on silicon wafer were successfully fabricated by changing the spinning speed or concentration of colloidal solution, as confirmed by FE-SEM. Based on these template films, a series of macroporous SiO2 films whose thicknesses varied from 300nm to ~1000nm were fabricated either by conventional sol - gel infiltration or gas phase deposition followed by thermal removal of organic template. Formations of SiO2 films consist of interconnected air balls with size ~100 nm were confirmed by FE-SEM and TEM. These highly porous SiO2 show very low refractive indices (<1.18) over a wide range of wavelength (from 200 to 1000nm) as shown by SE measurement. Refraction indices of SiO2 films at 633nm reported here are of ~1.10 which, to our best knowledge, are among the lowest values having been announced.

• Journal of Korean society of Dental Hygiene
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• v.13 no.1
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• pp.146-157
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• 2013

Objectives : The purpose of this paper is to analyze the effects of short-term oral health care on children at community care centers, in order to allow them to maintain good oral health. Methods : The SPSS (Statistical Package for Social Science), Window Version 18.0 was used to analyze the data for the children's present conditions of oral health; their ability to maintain good oral health; their general knowledge about oral health; changes in their oral health awareness; habit formations concerning oral health; and the satisfaction level of oral health education. Results : 1. While the average number of teeth before the program is 19.84(6.19), that of teeth after the program is 21.33(6.10). 2. Average test scores on oral health information of post-program are improved more than those of pre-program. 3. The 8th measurement of O'Leary plaque index is 3.27, which shows significant changes. 4. Satisfaction level with the program is 4.75(0.45), which shows that children are satisfied with the program. Conclusions : The paper shows that in order to maintain the oral health of children at community care centers, their habit formation and practice for the oral health is important. It also shows that cooperation among communities and public health centers is important to develop various oral health education programs like the program.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.16 no.2
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• pp.259-270
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• 1998

The purpose of this study is to develop the model curriculum for Geomatics/Geoinformatics. Geomatics/Geoinformatics are emerging discipline for spatial data acquisition and processing. They have multidisciplinary characteristics which include surveying, computer sciences, spatial data processing-related disciplines. This study carried out with the in-depth study to the related department's the academic characteristics and curriculums. Generally, the curriculum consists of surveying and information technology. They basically require mathematics, physics as prerequisites. The related-departments belong to the engineering or science part. So, We can conclude that the academic characteristics have to belong In engineering sides. Modern disciplines usually require balanced knowledge, and Geomatics/Geoinformatics have to the multidisciplinary approaches. This study shows 1) the model curriculum of Geomatics/Geoinformatics for the 21st century by analyzing the related departments' curriculum, it consist of surveying, computer/information sciences, sustainable urban management and related laws, etc., 2) the needs of the good cooperation among the related disciplines and industry for the development of standardized texts and curriculums, 3) the needs of new certification for Geomatics/Geoinformatics, etc.