• Title/Summary/Keyword: science knowledge formation

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Spontaneous pyometra induced by Staphylococcus aureus in a Maltese (황색포도상구균 감염에 의한 어린 말티스의 자궁축농증 증례)

  • Hong, Sun-Hwa;Chung, Yung-Ho;Han, Sang-Jun;Kim, Ok-Jin
    • Korean Journal of Veterinary Service
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    • v.35 no.1
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    • pp.63-67
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    • 2012
  • An 8-months-old young Maltese bitch was presented for investigation of anorexia and occasional vomiting. The body weight was 2 kg. Abdominal sonography demonstrated abnormal enlargement of uterus. The dog had been clinically and pathologically examined. Also, ovariohystectomy was performed. Staphylococcus aureus was identified in the pus-like materials of the uterine lumen. This case was confirmed as pyometra induced by Staphylococcus aureus. Gross examination of the dissected uterus revealed enlarged uterine horn, which had yellowish or brownish pus-like materials in the lumen. Also, there was several segments formation between the enlarged areas of left and right uterine horns. Histopathologically, endometritis and necrosis were present in uterine wall. The bitch made a complete recovery following an ovariohystectomy. This case was spontaneous pyometra induced by Staphylococcus species. On our knowledge, this is a very rare report of pyometra occurrence in young dog and Staphylococcus species-induced pyometra. This study may provide a valuable data on the study of canine pyometra.

REVIEW OF 15 YEARS OF HIGH-DENSITY LOW-ENRICHED UMo DISPERSION FUEL DEVELOPMENT FOR RESEARCH REACTORS IN EUROPE

  • Van Den Berghe, S.;Lemoine, P.
    • Nuclear Engineering and Technology
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    • v.46 no.2
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    • pp.125-146
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    • 2014
  • This review aims to provide a synthesis of the knowledge generated and the lessons learned in roughly 15 years of UMo dispersion fuel R&D in Europe through a series of irradiation experiments. A lot of irradiations were also performed outside of Europe, particularly in the USA, Russia, Canada, Korea and Argentina. In addition, a large number of out-of-pile investigations were done throughout the world, providing support to the understanding of the phenomena governing the UMo behaviour in pile. However, the focus of this article will be on the irradiations and Post-Irradiation Examination (PIE) results obtained in European experiments. The introduction of the article provides a historic overview of the evolution and progress in the high density UMo dispersion fuel development. The ensuing sections then provide further details on the various phases of the development, from the UMo dispersion in a pure Al matrix through the addition of Si to the matrix to address the interaction layer formation and finally to the more advanced solutions to the excessive swelling encountered in various experiments. This review was based only on published results or results that are currently in the process of being published.

Antiplatelet activity of esculetin through the down-regulation of PI3K/MAPK pathway

  • Lee, Dong-Ha
    • Journal of Applied Biological Chemistry
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    • v.64 no.3
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    • pp.317-322
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    • 2021
  • Among the different cardiovascular disorders (CVDs), the activation of platelets is a necessary step. Based on this knowledge, therapeutic treatments for CVDs that target the disruption of platelet activation are proving to be worthwhile. One such substance, a bioactive 6,7-dihydroxy derived from coumarin, is 6,7-Dihydroxy-2H-1-benzopyran-2-one (esculetin). This compound has demonstrated several pharmacological effects on CVDS as well as various other disorders including diabetes, obesity, and renal failure. In various reports, esculetin and its effect has been explored in experimental mouse models, human platelet activation, esculetin-inhibited collagen, and washed human platelets exhibiting aggregation via arachidonic acid. Yet, esculetin affected aggregation with agonists like U46619 or thrombin in no way. This study investigated esculetin and how it affected human platelet aggregation activated through U46619. Ultimately, we confirmed that esculetin had an effect on the aggregation of human platelets when induced from U46619 and clarified the mechanism. Esculetin interacts with the downregulation of both phosphoinositide 3-kinase/Akt and mitogen-activated protein kinases, important phosphoproteins that are involved in activating platelets and their signaling process. The effects of esculetin reduced TXA2 production, phospholipase A2 activation, and platelet secretion of intracellular granules (ATP/serotonin), ultimately causing inhibition of overall platelet aggregation. These results clearly define the effect of esculetin in inhibiting platelet activity and thrombus formation in humans.

Legal Stability and Determinants of Insurance Development in the Middle East and North Africa Region (MENA)

  • BEN DHIAB, Lassad;DKHILI, Hichem
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.2
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    • pp.141-149
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    • 2022
  • Despite the importance of the insurance business for financial and economic development, few studies have looked at the factors that influence its growth. This research adds to the body of knowledge by empirically examining the impact of numerous factors on the development of the insurance business in 15 Middle East and North African (MENA) countries from 2000 to 2017. The study looks at macroeconomic, demographic, and institutional factors as potential drivers of the insurance industry's growth, with the insurance premium as a percentage of GDP as the dependent variable. All variables are stationary at the first difference, according to the IPS panel unit root test. The Pedroni residual cointegration test, Kao residual cointegration test, and Johansen-Fisher panel cointegration tests are then used to look for long-run associations. The cointegration tests strongly suggest that the insurance premium and the various variables have long-run correlations. Findings from the Fully-Modified OLS imply that GDP per capita, gross capital formation, and the KOF economic globalization index have a positive long-term impact on the insurance business. The insurance business is also driven by combating corruption and the rule of law. The population and regulatory quality, on the other hand, have no significant impact.

Establishment of ICT Specialized Teaching-Learning System in the Era of Superintelligence, Super-Connectivity, and Super-Convergence

  • Seung-Woo LEE;Sangwon LEE
    • International journal of advanced smart convergence
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    • v.12 no.3
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    • pp.149-156
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    • 2023
  • Joint research on software, electronic engineering, computer engineering, and financial engineering and the use of ICT knowledge through network formation play an important role in strengthening science and technology-based innovation capabilities and facilitating the development and production process of products using new technologies. For the purpose of this study, I would like to strategically propose ICT specialized education in the 4th industrial revolution. To this end, the ICT specialization model, ICT specialization strategy analysis, and ICT specialization operation and effect were explored to establish ICT specialization strategies centered on software, electronic engineering, computer engineering, and financial engineering in the era of super-intelligence, hyper-connected, and hyper-convergence. Secondly, a roadmap for detailed promotion tasks related to efficient ICT characterization based on core strategies, detailed promotion tasks, and programs was proposed, focusing on talent related to ICT characterization. Thirdly, we would like to propose a reorganization of the academic structure and organization related to ICT characterization. Finally, we would like to propose the establishment of a future-oriented education system related to ICT specialization based on the advanced education and research environment.

An Evolutionary Concept Analysis of Pediatric Hospice and Palliative Care

  • Jung Hwa Lee;Soon Young Lee;Kyung Mi Cha
    • Journal of Hospice and Palliative Care
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    • v.27 no.2
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    • pp.51-63
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    • 2024
  • Purpose: This study aimed to clarify the concept of pediatric hospice and palliative care through conceptual analysis. It also sought to identify the differences between related concepts such as pediatric death care and pediatric spiritual care, in order to provide foundational data for the development of nursing theory and knowledge. Methods: A conceptual analysis of pediatric hospice and palliative care was conducted using Rodgers' evolutionary method. Out of 5,013 papers identified, 28 were selected for detailed reading and analysis. Results: Pediatric hospice and palliative care encompasses physical, psychological, social, mental, spiritual, and family care for children with acute and chronic diseases with uncertain prognoses ahead of death, as well as their families. Effective pediatric hospice and palliative care will require multidisciplinary team nursing, effective communication, and supportive policies. Conclusion: The findings of this study suggest that providing pediatric hospice and palliative care will lead to improvements in pain relief for children and families, the efficiency of responses to death in children, and the quality of life for children and families. The significance of this study is that it clearly clarifies the concept by analyzing pediatric hospice and palliative care using an evolutionary method.

An Exploration of Crops Listed in Gwanhyuji, an Agricultural Book in the Joseon Dynasty for the Promotion of the Diversity of Urban Gardens

  • Hong, In-Kyoung;Chae, Young;Lee, Sang-Mi;Jung, Young-Bin
    • Journal of People, Plants, and Environment
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    • v.22 no.4
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    • pp.341-354
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    • 2019
  • Urban agriculture, which promotes communication in vulnerable classes and the formation of social networks has been gaining attention with an emphasis on healthy city, elderly-friendly city, safe city and happy city as future keywords about urban life. There is a growing interest in public awareness in many areas such as health, society, economy, and ecology. As an attempt to improve the diversity of urban gardens, this study begins with collecting suitable crops for urban gardens from "Imwongyeongjeji (林園經濟志)," an encyclopedia written by Yoo-Ku Seo, a scholar in the 18-19th century. Out of those recorded in "Gwanhyuji (灌畦志)," 128 kinds of crops with linkage of the historical achievements of the realists who gave their priority to public welfare were selected and 53 crops which had traditionality, historicality, health functionality and popularity were finally selected. The properties (cold, warm, clam) of the selected crops were evenly distributed, and there was no crop that was hot and cool. In addition, the number of crops that have a sweet taste was the highest, followed by spicy and bitter, but there was no salty vegetable, which can be attributed to the fact that 12 namuls (wild vegetables) that grow in seas were excluded in this study since they were not suitable for urban gardens. Urban gardens can be transformed from those that focus on primary production and secondary consumption activities into a new resource that offers educational and traditional values by applying humanities to urban agriculture as a content resource in the era of cultural consilience and convergence. It is expected to satisfy urban residents' intellectual and participatory needs and to enhance the diversity and utility of urban gardens by applying traditional knowledge to a new model of urban agriculture. We hope that further research will be conducted to develop new types and models of urban agriculture going forward.

Tree Species Assemblages, Stand Structure, and Regeneration in an Old-Growth Mixed Conifer Forest in Kawang, Western Bhutan

  • Attila Biro;Bhagat Suberi;Dhan Bahadur Gurung;Ferenc Horvath
    • Journal of Forest and Environmental Science
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    • v.40 no.3
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    • pp.210-226
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    • 2024
  • Old-growth mixed-conifer forests in Bhutan are characterized by remarkable tree species compositional heterogeneity. However, our knowledge of tree species assemblages and their structural attributes in these forests has been limited. Therefore, forest classification has been reliant on a single dominant species. This study aimed to distinguish tree species assemblages in an old-growth mixed conifer forest in Western Bhutan and to describe their natural compositional and stand structural characteristics. Furthermore, the regeneration status of species was investigated and the quantity and quality of accumulated coarse woody debris were assessed. Ninety simple random sampling plots were surveyed in the study site between 3,000 and 3,600 meters above sea level. Tree, standing deadwood, regeneration, and coarse woody debris data were collected. Seven tree species assemblages were distinguished by Hierarchical Cluster Analysis and Indicator Species Analysis, representing five previously undescribed tree species associations with unique set of consistent species. Principal Component Analysis revealed two transitional pathways of species dominance along an altitudinal gradient, highly determined by relative topographic position. The level of stand stratification varied within a very wide range, corresponding to physiognomic composition. Rotated-sigmoid and negative exponential diameter distributions were formed by overstorey species with modal, and understorey species with negative exponential distribution. Overstorey dominant species showed extreme nurse log dependence during regeneration, which supports the formation of their modal distribution by an early natural selection process. This allows the coexistence of overstorey and understorey dominant species, increasing the sensitivity of these primary ecosystems to forest management.

Conceptual Approaches to Training Specialists Using Multimedia Technologies

  • Shchyrbul, Oleksandr;Babalich, Viktoriya;Mishyn, Sergii;Novikova, Viktoriia;Zinchenko, Lina;Haidamashko, Iryna;Kuchai, Oleksandr
    • International Journal of Computer Science & Network Security
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    • v.22 no.9
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    • pp.123-130
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    • 2022
  • Modernization of the educational sector requires globalization, democratization, and the transition to an information technology society. The main goal of education at the present stage is to solve the problem of ensuring the priority of the development of education and science. In modern conditions, the quality of training of qualified specialists is becoming particularly relevant. The great role of teacher education is emphasized by its main goal, which is to train specialists who can ensure the versatile and innovative development of a person as a person and the highest value of society, its mental, physical and aesthetic abilities, high moral qualities, and, consequently, the enrichment on this basis of the intellectual, creative and cultural potential of the people. Among the strategic tasks of modernizing higher education is to ensure informatization of the educational process and access to International Information Systems. The essence of the concept of multimedia is clarified. In the context of media education, multimedia lists a number of functions: informational, interpretive, cultural, entertainment, and educational. The need to meet the needs outlined in the article in the conditions of informatization of the educational process requires the teacher to have knowledge and skills in the field of multimedia pedagogical technologies, knowledge of advanced methods and means of modern science. It is considered what relevant concepts of media education have been developed and are being developed in Ukraine and form an important basis for the modernization of education, which will contribute to the construction of an information society in the country and the formation of civil society. Distance learning is considered - the most democratic form of education that allows broad segments of society to get an education. Distance learning methods are used in higher education institutions, in school education, in the system of advanced training of teachers, in the system of training managerial personnel.

Kepler's Scientific Problem Finding and the Abductive Reasoning in his Discovery of the Retinal Image Formation (Kepler의 망막 상 이론 형성 과정에서의 과학적 문제 발견과 귀추적 사고)

  • Kim, Young-Min
    • Journal of The Korean Association For Science Education
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    • v.26 no.7
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    • pp.835-842
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    • 2006
  • The aims of this study are to investigate how Kepler found a scientific problem for the retinal image theory and how abductive reasoning was used in his theory development, and to find implications for teaching creativity in science class from his thinking processes in the scientific discovery. Through the analysis of the related literatures, it was found that Kepler's problem finding in his retinal image theory came from the critical analysis of contemporary theories of vision, based on his relevant knowledge of optics, as he formulated his own hypothesis to build a new theory in eye vision employing optical phenomenon in spherical lens, which is a kind of abductive reasoning. From the results, three suggestions are proposed, that: (a) in the development of creativity teaching material, the situations like Kepler's problem finding need to be included in the programs; (b) it should be taught that relevant scientific knowledge is important for problem finding and hypothesis formulating; and (c) the experience of successful problem solving by themselves could help them find new scientific problem(s).