• Title/Summary/Keyword: science and engineering research and development

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A survey for research and application of quality science in CHINA

  • Xu, Jichao
    • International Journal of Quality Innovation
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    • v.1 no.1
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    • pp.38-57
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    • 2000
  • Quality science may be defined as the subject promoting both quality and productivity, which may include quality management, quality engineering and technology innovation. The research and application of quality science have been in existence for many years in China. This report first reviews its recent history as well as the analysis of the status quo. Finally, a prospectus and comments section for the future of quality science points out the development trends and its significant effectiveness on China's modem economics.

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PGC-Enriched miRNAs Control Germ Cell Development

  • Bhin, Jinhyuk;Jeong, Hoe-Su;Kim, Jong Soo;Shin, Jeong Oh;Hong, Ki Sung;Jung, Han-Sung;Kim, Changhoon;Hwang, Daehee;Kim, Kye-Seong
    • Molecules and Cells
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    • v.38 no.10
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    • pp.895-903
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    • 2015
  • Non-coding microRNAs (miRNAs) regulate the translation of target messenger RNAs (mRNAs) involved in the growth and development of a variety of cells, including primordial germ cells (PGCs) which play an essential role in germ cell development. However, the target mRNAs and the regulatory networks influenced by miRNAs in PGCs remain unclear. Here, we demonstrate a novel miRNAs control PGC development through targeting mRNAs involved in various cellular pathways. We reveal the PGC-enriched expression patterns of nine miRNAs, including miR-10b, -18a, -93, -106b, -126-3p, -127, -181a, -181b, and -301, using miRNA expression analysis along with mRNA microarray analysis in PGCs, embryonic gonads, and postnatal testes. These miRNAs are highly expressed in PGCs, as demonstrated by Northern blotting, miRNA in situ hybridization assay, and miRNA qPCR analysis. This integrative study utilizing mRNA microarray analysis and miRNA target prediction demonstrates the regulatory networks through which these miRNAs regulate their potential target genes during PGC development. The elucidated networks of miRNAs disclose a coordinated molecular mechanism by which these miRNAs regulate distinct cellular pathways in PGCs that determine germ cell development.

REVIEW OF SUPERCRITICAL CO2 POWER CYCLE TECHNOLOGY AND CURRENT STATUS OF RESEARCH AND DEVELOPMENT

  • AHN, YOONHAN;BAE, SEONG JUN;KIM, MINSEOK;CHO, SEONG KUK;BAIK, SEUNGJOON;LEE, JEONG IK;CHA, JAE EUN
    • Nuclear Engineering and Technology
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    • v.47 no.6
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    • pp.647-661
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    • 2015
  • The supercritical $CO_2$ (S-$CO_2$) Brayton cycle has recently been gaining a lot of attention for application to next generation nuclear reactors. The advantages of the S-$CO_2$ cycle are high efficiency in the mild turbine inlet temperature region and a small physical footprint with a simple layout, compact turbomachinery, and heat exchangers. Several heat sources including nuclear, fossil fuel, waste heat, and renewable heat sources such as solar thermal or fuel cells are potential application areas of the S-$CO_2$ cycle. In this paper, the current development progress of the S-$CO_2$ cycle is introduced. Moreover, a quick comparison of various S-$CO_2$ layouts is presented in terms of cycle performance.

The effect of combined carbonation and steam curing on the microstructural evolution and mechanical properties of Portland cement concrete

  • Kim, Seonhyeok;Amr, Issam T.;Fadhel, Bandar A.;Bamagain, Rami A.;Hunaidy, Ali S.;Park, Solmoi;Seo, Joonho;Lee, H.K.
    • Advances in concrete construction
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    • v.11 no.5
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    • pp.367-374
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    • 2021
  • The present study investigated the effect of the combined carbonation and steam curing on the physicochemical properties and CO2 uptake of the Portland cement concrete. Four different curing regimes were adopted during the initial 10 h of curing to evaluate the potential of carbonation curing as an alternative to conventional steam curing in the precast concrete industry from environmental and practical viewpoints. Four combinations of carbonation and steam curing conditions were applied as curing regimes to the samples at an early age. The test results indicated that the samples treated with the combined carbonation and steam curing exhibited higher early strength development compared to the other samples, signifying that carbonation curing can reduce the production time of precast concrete. Furthermore, the CO2 uptake capacity of the samples was calculated and found to be as high as 18% with respect to the mass of the paste samples. Hence, the simultaneous utilization of steam and CO2 for the fabrication of precast concrete members has the potential to make precast concrete greener and more cost-effective.

High Performance Computing Applications In Korean Trainer Development Program

  • Roh Hyun-Woo;Kim Si-Hong;Jeong In-Myon
    • 한국전산유체공학회:학술대회논문집
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    • 2006.05a
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    • pp.121-125
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    • 2006
  • CFD has been used in aircraft development and broaden its influence in various fields of industries. This paper briefly introduces the historical trends of computing system, the overview of CFD applications in Korean Supersonic Trainer Development Program and the demand for CFD software in industry points of view.

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