• 제목/요약/키워드: school vaccination

검색결과 315건 처리시간 0.022초

산업장 근로자의 건강증진 프로그램 요구도 (Need Assessment for Worksite Health Promotion Program)

  • 송연이;장정희
    • 한국직업건강간호학회지
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    • 제8권2호
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    • pp.115-129
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    • 1999
  • This study was conducted to investigate the kinds of health promotion program which workers want, worker's intention for participation, proper method, time, duration and manager. A self-administered questionnaire method was used to collect data from 412 employees of 3 worksites in Chungpook and Kyungkee. This survey was carried out from Aug. 10 to Aug. 20, 1998. The results of this study are as follows: 1. In male, among health promotion programs, favorite ones were physical fitness(32.2%), periodic health check-up(24.6%), and stress management(18.0%). In female, among health promotion programs, favorite ones were periodic health check-up(26.0%), physical fitness(22.0%), and body weight control(19.5%). 2. The more young subjects are, the more they like physical fitness program, and the female like body weight control program regardless of BMI. Manufacturing worker preferred back pain prevention program to clerical worker did. In female, drinker preferred stress management program to non-drinker did. 3. The more old subjects are, the more they like back pain prevention program, and non-smoker preferred body weight control program to smoker did. 4. In health promotion program format which the subjects wanted, learning of self-examination techniques was 41.1%, worksite screening was 3l.0%, availability of pamphlets and audiovisual materials was 20.0%, presentation of worksite educational sessions was 7.9%, and the most wanted manager for the program was medical doctor and then nurse, physical trainer, psychological counselor. The favorite health promotion program duration was less than 30 minutes(49.6%), and the favorite time was before work(49.6%). 5. Among respondents, 48.5% was smokers, 81.8% was drinkers, 39.9% engaged in the regular exercise, 68.2% engaged in regular diet habit. In vaccination, 50.2%, if possible, wanted to be vaccinated and 37.6% never wanted to be vaccinated. 6. Ex-smoker, ex-drinker, the subjects in the regular exercise, and in the regular diet habit responded they were in good health. There was a significant difference between exercise and health status. Need and intention for participation of health promotion program were high in ex-smoker, ex-drinker, the subjects in the regular exercise, and in the regular diet habit. According to results for this study, if the favorite programs, exercise, periodic health check-up, stress management program, are operated at a proper time and with managers they want, this programs can really raise the participation of employees. And as employees want to learn self-examination techniques if worksite educational sessions are performed, health promotion program can effectively be operated.

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1993년도 성남지역에서 유행한 홍역 환아에서의 홍역 특이 항체 반응 (Response of Measles-specific Antibody in Children with Measles During Measles Epidemic in Seongnam, 1993)

  • 김지연;박윤형;김순기;최연화;이환종;손병관
    • Pediatric Infection and Vaccine
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    • 제4권1호
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    • pp.126-132
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    • 1997
  • 목 적 : 높은 예방접종율에도 불구하고 흥역이 계속 발생하는 것은 1차 백신 실패 또는 2 차 백신 실패 등의 논란을 자아내고 있다. 이에 저자들은 1993년 전국적으로 홍역이 유행하였을 당시 인구 밀집 대도시인 성남지역에서 그 당시 홍역에 이환되었던 일부 소아를 대상으로 특이 혈청학적 검사를 실시하였다. 대상 및 방법 : 1993년 홍역이 유행할 당시 임상진단 기준에 따라서 홍역으로 진단된 초등학교생을 대상으로 학교에 의뢰하여 93년 12월 10일부터 5일간 채혈한 후, 혈청을 분리한 후 $-20^{\circ}C$ 냉장고에 보관한 후 2개월 지나 검사하였다. Behring사의 시약을 사용하여 ELISA(Enzyme linked immunosorbent assay)방법에 의해 혈청내 홍역 특이 IgM 항체 (measles-specific IgM) 및 IgG를 검사하였다. 결 과 : 1) 총 126명 (남녀비=1:1)으로 발병시 연령은 5세 6명, 6세 11명, 7세 20명, 8세 39명, 9세 22명, 10세 11명, 11세 11명, 12세 6명으로 8세 전후에 가장 많은 빈도 보였다. 홍역은 여름에 발생하기 시작한 홍역은 9월부터 증가하기 시작하여 11월에 정점을 이루었다. 2) 홍역환자 126명중 99명(78.6%)에서 MMR접종력이 있었다. MMR접종자 99명 가운데 홍역 특이 IgM 항체에 양성은 80.8%(80/99)에서 관찰되었고, MMR 비접종자 27명 가운데 26명 (96.3%)에서 양성율을 보였다. 3) 홍역 특이 IgG 항체 반응결과 MMR 접종력이 있는 99명 중 90명(90.9%)에서, MMR 비접종군 27명중 23명(85.2%)에서 양성반응을 보였다. 흥역특이 IgG 항체반응은 MMR 접종력이 있는 아동 33명중 30례(90.1%)에서 양성을 보였다. 결 론 : MMR 접종력이 있는 아동의 상당수는 시간에 따른 항체가의 감소로 인해 홍역이 발생하였을 가능성을 배제할 수 없으나, 상당수의 환자가 IgM 항체 양성을 보인 것은 1차 백신 실패가 여전히 중요하다는 것을 의미하는 것으로 생각한다. 이를 확인하기 위해서는 보다 많은 아동을 대상으로 한 연구가 필요할 것으로 생각한다.

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농촌(農村) 주민(住民)들의 의료필요도(醫療必要度)에 관(關)한 연구(硏究) (A Study Concerning Health Needs in Rural Korea)

  • 이성관;김두희;정종학;정극수;박상빈;최정헌;홍순호;라진훈
    • Journal of Preventive Medicine and Public Health
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    • 제7권1호
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    • pp.29-94
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    • 1974
  • Today most developed countries provide modern medical care for most of the population. The rural area is the more neglected area in the medical and health field. In public health, the philosophy is that medical care for in maintenance of health is a basic right of man; it should not be discriminated against racial, environmental or financial situations. The deficiency of the medical care system, cultural bias, economic development, and ignorance of the residents about health care brought about the shortage of medical personnel and facilities on the rural areas. Moreover, medical students and physicians have been taught less about rural health care than about urban health care. Medical care, therefore, is insufficient in terms of health care personnel/and facilities in rural areas. Under such a situation, there is growing concern about the health problems among the rural population. The findings presented in this report are useful measures of the major health problems and even more important, as a guide to planning for improved medical care systems. It is hoped that findings from this study will be useful to those responsible for improving the delivery of health service for the rural population. Objectives: -to determine the health status of the residents in the rural areas. -to assess the rural population's needs in terms of health and medical care. -to make recommendations concerning improvement in the delivery of health and medical care for the rural population. Procedures: For the sampling design, the ideal would be to sample according to the proportion of the composition age-groups. As the health problems would be different by group, the sample was divided into 10 different age-groups. If the sample were allocated by proportion of composition of each age group, some age groups would be too small to estimate the health problem. The sample size of each age-group population was 100 people/age-groups. Personal interviews were conducted by specially trained medical students. The interviews dealt at length with current health status, medical care problems, utilization of medical services, medical cost paid for medical care and attitudes toward health. In addition, more information was gained from the public health field, including environmental sanitation, maternal and child health, family planning, tuberculosis control, and dental health. The sample Sample size was one fourth of total population: 1,438 The aged 10-14 years showed the largest number of 254 and the aged under one year was the smallest number of 81. Participation in examination Examination sessions usually were held in the morning every Tuesday, Wenesday, and Thursday for 3 hours at each session at the Namchun Health station. In general, the rate of participation in medical examination was low especially in ages between 10-19 years old. The highest rate of participation among are groups was the under one year age-group by 100 percent. The lowest use rate as low as 3% of those in the age-groups 10-19 years who are attending junior and senior high school in Taegu city so the time was not convenient for them to recieve examinations. Among the over 20 years old group, the rate of participation of female was higher than that of males. The results are as follows: A. Publie health problems Population: The number of pre-school age group who required child health was 724, among them infants numbered 96. Number of eligible women aged 15-44 years was 1,279, and women with husband who need maternal health numbered 700. The age-group of 65 years or older was 201 needed more health care and 65 of them had disabilities. (Table 2). Environmental sanitation: Seventy-nine percent of the residents relied upon well water as a primary source of dringking water. Ninety-three percent of the drinking water supply was rated as unfited quality for drinking. More than 90% of latrines were unhygienic, in structure design and sanitation (Table 15). Maternal and child health: Maternal health Average number of pregnancies of eligible women was 4 times. There was almost no pre- and post-natal care. Pregnancy wastage Still births was 33 per 1,000 live births. Spontaneous abortion was 156 per 1,000 live births. Induced abortion was 137 per 1,000 live births. Delivery condition More than 90 percent of deliveries were conducted at home. Attendants at last delivery were laymen by 76% and delivery without attendants was 14%. The rate of non-sterilized scissors as an instrument used to cut the umbilical cord was as high as 54% and of sickles was 14%. The rate of difficult delivery counted for 3%. Maternal death rate estimates about 35 per 10,000 live births. Child health Consultation rate for child health was almost non existant. In general, vaccination rate of children was low; vaccination rates for children aged 0-5 years with BCG and small pox were 34 and 28 percent respectively. The rate of vaccination with DPT and Polio were 23 and 25% respectively but the rate of the complete three injections were as low as 5 and 3% respectively. The number of dead children was 280 per 1,000 living children. Infants death rate was 45 per 1,000 live births (Table 16), Family planning: Approval rate of married women for family planning was as high as 86%. The rate of experiences of contraception in the past was 51%. The current rate of contraception was 37%. Willingness to use contraception in the future was as high as 86% (Table 17). Tuberculosis control: Number of registration patients at the health center currently was 25. The number indicates one eighth of estimate number of tuberculosis in the area. Number of discharged cases in the past accounted for 79 which showed 50% of active cases when discharged time. Rate of complete treatment among reasons of discharge in the past as low as 28%. There needs to be a follow up observation of the discharged cases (Table 18). Dental problems: More than 50% of the total population have at least one or more dental problems. (Table 19) B. Medical care problems Incidence rate: 1. In one month Incidence rate of medical care problems during one month was 19.6 percent. Among these health problems which required rest at home were 11.8 percent. The estimated number of patients in the total population is 1,206. The health problems reported most frequently in interviews during one month are: GI trouble, respiratory disease, neuralgia, skin disease, and communicable disease-in that order, The rate of health problems by age groups was highest in the 1-4 age group and in the 60 years or over age group, the lowest rate was the 10-14 year age group. In general, 0-29 year age group except the 1-4 year age group was low incidence rate. After 30 years old the rate of health problems increases gradually with aging. Eighty-three percent of health problems that occured during one month were solved by primary medical care procedures. Seventeen percent of health problems needed secondary care. Days rested at home because of illness during one month were 0.7 days per interviewee and 8days per patient and it accounts for 2,161 days for the total productive population in the area. (Table 20) 2. In a year The incidence rate of medical care problems during a year was 74.8%, among them health problems which required rest at home was 37 percent. Estimated number of patients in the total population during a year was 4,600. The health problems that occured most frequently among the interviewees during a year were: Cold (30%), GI trouble (18), respiratory disease (11), anemia (10), diarrhea (10), neuralgia (10), parasite disease (9), ENT (7), skin (7), headache (7), trauma (4), communicable disease (3), and circulatory disease (3) -in that order. The rate of health problems by age groups was highest in the infants group, thereafter the rate decreased gradually until the age 15-19 year age group which showed the lowest, and then the rate increased gradually with aging. Eighty-seven percent of health problems during a year were solved by primary medical care. Thirteen percent of them needed secondary medical care procedures. Days rested at home because of illness during a year were 16 days per interviewee and 44 days per patient and it accounted for 57,335 days lost among productive age group in the area (Table 21). Among those given medical examination, the conditions observed most frequently were respiratory disease, GI trouble, parasite disease, neuralgia, skin disease, trauma, tuberculosis, anemia, chronic obstructive lung disease, eye disorders-in that order (Table 22). The main health problems required secondary medical care are as fellows: (previous page). Utilization of medical care (treatment) The rate of treatment by various medical facilities for all health problems during one month was 73 percent. The rate of receiving of medical care of those who have health problems which required rest at home was 52% while the rate of those who have health problems which did not required rest was 61 percent (Table 23). The rate of receiving of medical care for all health problems during a year was 67 percent. The rate of receiving of medical care of those who have health problems which required rest at home was 82 percent while the rate of those who have health problems which did not required rest was as low as 53 percent (Table 24). Types of medical facilitied used were as follows: Hospital and clinics: 32-35% Herb clinics: 9-10% Drugstore: 53-58% Hospitalization Rate of hospitalization was 1.7% and the estimate number of hospitalizations among the total population during a year will be 107 persons (Table 25). Medical cost: Average medical cost per person during one month and a year were 171 and 2,800 won respectively. Average medical cost per patient during one month and a year were 1,109 and 3,740 won respectively. Average cost per household during a year was 15,800 won (Table 26, 27). Solution measures for health and medical care problems in rural area: A. Health problems which could be solved by paramedical workers such as nurses, midwives and aid nurses etc. are as follows: 1. Improvement of environmental sanitation 2. MCH except medical care problems 3. Family planning except surgical intervention 4. Tuberculosis control except diagnosis and prescription 5. Dental care except operational intervention 6. Health education for residents for improvement of utilization of medical facilities and early diagnosis etc. B. Medical care problems 1. Eighty-five percent of health problems could be solved by primary care procedures by general practitioners. 2. Fifteen percent of health problems need secondary medical procedures by a specialist. C. Medical cost Concidering the economic situation in rural area the amount of 2,062 won per residents during a year will be burdensome, so financial assistance is needed gorvernment to solve health and medical care problems for rural people.

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농촌지역(農村地域) 주민(住民)들의 보건의료원(保健醫療院) 이용양상(利用樣相)과 관련요인(關聯要因) (Health Medical Center Utilization Pattern and Its Related Factors among the Rural Inhabitants)

  • 황병덕;박재용
    • 농촌의학ㆍ지역보건
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    • 제18권1호
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    • pp.77-91
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    • 1993
  • 농촌지역 주민들의 보건의료원에 대한 인식도 및 이용양상을 파악하여 보건의료원 제도와 관련된 연구에 기초자료를 제공하고자 1990년 9월 24일부터 90년 9월 28일 까지 5일간 정상북도 울진군 소재 국민학교 3개교와 중학교 3개교의 학부모들에게 설문지를 배부, 회수된 832가구의 가구원 754명을 대상으로 분석한 결과를 요약하면 다음과 같다. 응답자는 남자 60.3%, 여자 39.7%였고 연령은 30, 40대가 81.3%로 대부분을 차지하였으며, 교육수준은 고졸이 40.3%, 의료보장형태로는 지역의료보험이 44.1%를 차지하였다. 응답자의 58.4%가 보건의료원이라는 명칭을 알고 있었는데, 응답자의 학력과 수입이 높을 수록 그리고 거주지역이 보건의료원에 근접한 지역일수록 보건의료원에 대한 인식도가 높았다(p<0.01). 보건의료원의 진료사업 내용중에서 의료보호대 상자 진료와 치과진료를, 각각 35.1%와 31.0%가 알고 있었으며, 보건예방서비스 사업에서는 예방접종사업을 36.1%로 가장 많이 인지하고 있었는데, 학력과 지리적 근접도가 높을수록 보건의료원의 사업내용 인지도는 높게 나타났다. 보건의료원의 연간 외래이용율과 예방서비스 이용율은 대상자 100명당 11.1회 및 4.5회였으며, 입원이용율은 10,000명당 34.6회였다. 보건의료원 이용동기는 잘나아서(45.7%), 약이 좋아서 (45.2%), 거리가 가까워서(42.9%) 순이었다. 일반병의원과 비교해서 보건의료원의 진료수준이 더 좋다고 응답한 이용자는 16.3% 였고, 더 못하다는 19.0%였다. 또한 보건의료원의 진료비가 저렴하다고 한 응답자는 61.5%인데 비해 비싸다고한 경우는 3.9%였다. 보건의료원 이용시의 교통수단으로는 도보가 55.0%, 버스가 35.5%로 대부분이었다. 보건의료원 이용시 느낀 불편사항으로는 장시간 대기가 46.7%로 가장 많았고, 그 다음으로 이용시간이 제한되어 있어서가 17.8%였다. 보건의료원을 한번도 이용하지 않은 이유로는 아픈적이 없어서가 33.5%, 교통이 불편하고 거리가 멀어서가 28.0%, 장시간 대기한다고 해서가 12.8%순으로 나타났다. 이상과 같이 아직도 보건의료원에 대한 인식이 낮고, 잘못 인식하고 있는 주민이 많기 때문에 보건의료원에 대한 전반적인 홍보가 필요할 것으로 보이며, 보건의료원의 이용율을 높이기 위해서는 의료시설, 장비확충과 더불어 의료진의 보강이 필요하고 관리의 효율성도 고려해야 할 것으로 생각된다.

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의약분업(醫藥分業) 실시(實施)에 따른 보건소(保健所)의 내부변화(內部變化)와 업무개선방안(業務改善方案) (Internal Changes and Countermeasure for Performance Improvement by Separation of Prescribing and Dispensing Practice in Health Center)

  • 정명선;감신;김태웅
    • 농촌의학ㆍ지역보건
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    • 제26권1호
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    • pp.19-35
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    • 2001
  • 보건소의 의약분업 시행에 따른 업무변화와 업무 개선방안에 대해 조사 분석하여 보건소의 기능 및 역할 재정립에 필요한 기초자료를 얻고자 2001년 4월과 5월에 경상북도내 25개 보건소와 대구광역시 6개 보건소의 소장 또는 과장에게 의약분업 실시 전후의 보건소 업무 및 진료실적변화 정도를 조사하였고, 이와 함께 보건소 공무원 221명에게 의약분업에 따른 보건소 업무개선방안에 대해 설문 조사하였다. 31개 대상 보건소 가운데 77.4%인 24개 보건소가 주민진료편의 조치를 취하였다고 하였다. 주민 진료편의 조치를 한 보건소의 조치내용으로 약국배치도마련(73.9%), 인테리어 개선(39.1%), 전자처방전달시스템 도입(34.8%) 순이었다. 의약분업 실시 후 의사는 대상 보건소의 3.2%에서 감소하였다. 의약분업에 따라 월평균 진료건수는 대상 보건소의 58.1%에서 감소하였다고 하였고, 조제건수는 96.4%, 총진료비는 80.6%, 본인부담금은 80.6%, 약품구입비는 96.7%의 보건소에서 감소하였다고 하였다. 의약분업 실시 이후 진료부문에 비해 보건사업 부문의 비중은 54.2%의 보건소에서 증가하였다고 하였다. 의약분업 전후이 분기별 진료실적을 분석한 결과 진료실인원은 의약분업이전과 비교하여 의약분업 이후에 감소하였고, 진료연인원은 군보건소와 보건의료원은 감소하였으며, 시화 구보건소는 감소했다가 점차 증가하고 있다. 조제건수 총진료비 본인부담금 약품구입비는 크게 감소하였다. 보건소 공무원들은 의약분업 실시 이후 진료부문의 기능에 대해서는 57.6%가 축소시켜야 한다고 하였고, 보건소에서 우선적으로 개선해야 할 부분으로는 보건사업내용 개발(62.4%), 인력재배치(51.6%), 사업우선순위 결정(48.4%), 조직개편(36.2%), 진료서비스의 질 향상(32.1%), 예산재배치(23.1%) 순으로 응답하였다. 보건소의 이미지를 개선하기 위해서는 지역주민건강정보관리 강화(60.7%)가 가장 시급하다고 하였으며 홍보를 통한 보건소의 이용 확대(15.8%), 보건소 공무원의 친절(15.3%), 건강상담요원 배치(8.2%) 순이었다. 의약분업 실시 이후 바람직한 보건소 역할 설정을 위하여 보건소 전체 업무 영역에 대해 의약분업 이전과 이후에 상대비중을 매기도록 한 결과 25개 세부영역 중 일반진료 및 응급진료 영역만 모두 상대비중이 높아졌다. 의약분업 이후 보건소가 중점을 두어야 할 우선 순위 5위까지의 업무영역은 순서대로 예방접종, 건강증진, 모자보건, 급만성전염병, 지역보건의료계획 이었다. 향후 보건소가 바람직한 공공보건의료조직으로 기능 및 역할을 재정립하기 위해서는 의약분업이라는 중대한 보건의료환경변화를 계기로 진료부문의 기능은 축소하되 노후시설 장비의 개선, 진료방식의 다양화, 건강정보관리 강화 등 진료서비스의 내용과 질에 있어서는 강화하는 방향으로 나아가야 할 것이다. 또한 인력재배치 및 조직개편과 함께 다양한 보건사업의 개발과 지역특성에 맞는 사업우선순위에 의해 예방접조, 건강증진, 모자보건, 급 만성전염병, 지역보건의료계획 수립, 구강보건, 만성퇴행성질환 등 지역주민의 건강증진 질병예방 기능을 강화하되 지역특성(대도시, 중소도시, 농어촌)에 맞게 예방위주의 건강 증진업무와 환자 진료업무의 비중을 차별화 시키는 방향으로 개선해 나가야 할 것이다.

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약사의 백신에 대한 교육의 필요성 및 환자 상담을 위한 소책자 개발 (The Necessity of Vaccine Education for Pharmacists and Development of a Vaccine Leaflet for Patient Counseling)

  • 김미경;김현아;조은;이옥상;임성실
    • 한국임상약학회지
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    • 제21권3호
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    • pp.280-291
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    • 2011
  • Vaccines are products for immunization which can provoke antibodies by eliciting immune reponses without causing disease and have played an important role in preventing fatal and contagious diseases as well as H1N1 influenza. They are classified by two following categories; lived attenuated vaccine and killed vaccine and currently commonly using vaccines are BCG, diphtheria, tetanus, mumps, measles, rubella, polio, Haemophilus influenza type b, hepatitis B, influenza etc. All vaccines must be used correctly to reach optimal therapeutic goals and also informed well to patients to decrease potential problems. In order to do, pharmacists must have good knowledge of vaccines. The purpose of this study is to evaluate the necessity of vaccine education for pharmacists and develop a vaccine leaflet for patient counseling. We have performed a survey with questionnaire for a total of 176 pharmacists and nurses(hospital pharmacists, n=65; community pharmacists, n=50; hospital nurses, n=61) from January 27th to March 12th, 2010. The questionnaire includes items about vaccine education and counseling and 12 quizzes to evaluate responders' knowledge of vaccines. We used the SPSS(Version 12. for windows) program to analyze the data. In results, 94.9% of all responders said they had not been educated on vaccines. And only 1.1% of all responders said they know about vaccines enough to counsel patients. Pharmacists who have an experience recommending vaccines to other people are 21.7%. On the other hand, nurses who have an experience recommending vaccines to other people are 55.7%(p=0.000). The mean number of correct answers at the 12 quizzes are followings; hospital pharmacist, 8.1; community pharmacist, 6.1, hospital nurses, 6.2(p=0.000). A vaccine leaflet for patient counseling is developed with several references. In conclusion, due to no opportunity of vaccine education, pharmacists have no confidence to counsel patients and lack of knowledge of vaccine. But importance of vaccine's role is increasing, pharmacists should counsel patients in vaccination. So they need vaccine education and a vaccine leaflet will be helpful for their counseling.

Evaluation of Protective Immune Response Induced by a DNA Vaccine Encoding GRA8 against Acute Toxoplasmosis in a Murine Model

  • Chu, Jia-Qi;Huang, Shuai;Ye, Wei;Fan, Xuan-Yan;Huang, Rui;Ye, Shi-Cai;Yu, Cai-Yuan;Wu, Wei-Yun;Zhou, Yu;Zhou, Wei;Lee, Young-Ha;Quan, Juan-Hua
    • Parasites, Hosts and Diseases
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    • 제56권4호
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    • pp.325-334
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    • 2018
  • Toxoplasma gondii is an apicomplexan zoonotic protozoan parasite that infects most species of warm-blooded animals, including humans. The heavy incidence and severe or lethal damage caused by T. gondii infection clearly indicate a need for the development of an effective vaccine. T. gondii GRA8 is a member of the dense granules protein family and is used as a marker of acute infection. In the present study, we evaluated the protective immunity induced by DNA vaccination based on a recombinant eukaryotic plasmid, pDsRed2-GRA8, against acute toxoplasmosis in mice. BALB/c mice were intramuscularly immunized with the pDsRed2-GRA8 plasmid and then challenged by infection with the highly virulent GFP-RH strain of T. gondii. The specific immune responses and protective efficacy against T. gondii of this vaccine were analyzed by measuring cytokine and serum antibody titers, splenocyte proliferation assays, and the survival times of mice after challenge. Our results showed that mice immunized with pDsRed2-GRA8 demonstrated specific humoral and cellular responses, induced higher IgG antibody titers with predominant IgG2a production; increased levels of IL-10, IL-12 (p70), $IFN-{\gamma}$, $TNF-{\alpha}$, and splenocyte proliferation; and prolonged survival times compared to those of control mice. The present study showed that DNA immunization with pDsRed2-GRA8 induced humoral and cellular immune responses, and all immunized mice showed greater Th1-type immune responses and longer survival times than those of control mice. These results indicated that T. gondii GRA8 DNA immunization induces a partial protective effect against acute toxoplasmosis.

국내 산란계에서 닭 전염성기관지염의 계군 수준 유병율과 위험요인 (Flock-level Seroprevalence of and Risk Factors for Infectious Bronchitis Virus in Korean Laying-hen Flocks)

  • 박선일
    • 한국임상수의학회지
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    • 제26권2호
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    • pp.134-137
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    • 2009
  • 국내 산란계에서 전염성기관지염(IB)에 의한 경제적 피해가 심각하지만 IB 바이러스(IBV)에 대한 혈청학적 유병율과 위험요인에 대한 연구는 잘 알려져 있지 않은 실정이다. 2007년 5월부터 10월까지 강원, 충북 및 충남 지역의 3,000수 이상을 사육하는 41개 산란 계군 중 18주령 이상을 대상으로 총 820수(계군 당 20수)에서 혈액시료를 채취하였다. 이러한 표본크기는 평균 계군 크기 3,000-65,000수, 최소 기대 유병율 15%, 95% 신뢰수준을 고려하여 계산하였다. 혈액시료는 혈구응집억제검사를 사용하여 IBV 항체역가를 측정하였다. 41개 계군 중 19개 계군이 양성으로 확인되어 계군 수준의 유병율은 46.3%(95% CI, 31.1-66.6)로 지역별로 유의한 차이는 없었다(X=1.205, P>0.05). 전체적으로 계군 당 1-8수가 감염 역가를 보였으나 양성 계군 중 11개 계군에서는 1-2수만이 감염역가를 보였다. 로지스틱모형을 이용한 위험요인 분석에서 IBV 혈청양성과 연관된 유의한 변수는 없는 것으로 나타나 향후 광범위한 산란 계군을 대상으로 사양관리와 백신접종 등을 고려한 종주연구가 필요할 것으로 사료된다.

부산지역 여성의 자궁경부질환과 HPV의 상관관계 (Correlation between Uterine Cervical Lesion and HPV in Busan Region)

  • 손창민;박충무
    • 대한임상검사과학회지
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    • 제51권4호
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    • pp.406-413
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    • 2019
  • 2013년 1월부터 2016년 3월 사이 인제대학교 해운대백병원에 내원한 환자를 대상으로 HPV genotype 분석 후 세포학적 검사 결과, 조직학적 검사 결과와 비교하였다. 총 검사대상 2,130건 중 58.9%인 1,254건은 HPV 양성으로, 41.1%인 876건은 HPV 음성으로 분석되었다. HPV 양성검체 중 단순감염은 58.4%인 732건, 복합감염은 41.6%인 522건이었다. 감염비율은 HPV 16, 68, 56의 순으로 각각 7.1%인 152건, 4.6%인 97건, 3.8%인 80건으로 나타났다. HR HPV 감염은 40대, 30대, 50대 순으로 높은 감염률을 보였고, LR HPV 감염은 40대, 50대, 30대 순으로 높은 감염률을 보였다. 조직병리학적 분석 결과 CIN 2 이상으로 나온 HPV 16, 68, 56 건수는 329건 중 155건으로 47.1%(155/329)로 분석되었다. 부산지역 여성의 HPV subtype 감염은 주로 16, 68, 56, 58, 51과 관련이 있었으나, 이중 68, 56, 51형은 현재 시판 중인 Gardasil 9가 백신으로도 예방할 수 없는 유전자형이었다. 이 연구를 통해 부산 지역의 HPV 예방 접종을 위한 프로그램에 대한 중요한 기준 데이터를 제공할 수 있을 것으로 사료된다.

손실과 이득 메시지 프레이밍 광고상황에서 COVID-19에 대한 관여와 사회적 거리두기 실천의도와의 관계에 영향을 미치는 광고태도의 매개효과 (Mediating Effect of Attitude toward Advertisement on the Relationship between COVID-19 Involvement and Behavioral Intention of Social Distancing in Loss versus Gain Advertising Context)

  • 최자인;최자윤
    • 한국융합학회논문지
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    • 제12권12호
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    • pp.467-477
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    • 2021
  • COVID-19 감염예방을 위한 손실과 이득 메시지 프레이밍 광고상황에서 COVID-19에 대한 관여와 사회적 거리두기 실천의도와의 관계를 확인하고 이들 간 관계에서 광고태도의 매개효과를 확인하였다. 대한민국에 거주하는 19세 이상 성인 379명을 대상으로 하였다. 2개 유형의 메시지 프레이밍 중 1개 광고를 무작위 할당하여 보도록 한 후 COVID-19에 대한 관여, 광고태도 및 사회적 거리두기 실천의도를 측정하였다. COVID-19에 대한 관여가 사회적 거리두기 실천의도에 영향을 미쳤는데 COVID-19에 관여함으로써 COVID-19에 대한 위험이나 심각성을 인식하여 위험감소행위를 시도하기 때문으로 생각되어 COVID-19에 대한 관여를 높이는 전략이 매우 필요하다. 또한 광고태도가 COVID-19에 대한 관여와 사회적 거리두기 실천의도와의 관계에서 매개작용을 하였다. 따라서 병원이나 지역사회 종사 간호사가 현장에서 대중과 소통하고 정책을 보급할 때 긍정적 광고태도를 유도할 수 있는 효과적인 메시지를 제시함으로써 건강관리 리더로서 역할을 충실히 해 나가야 할 것이다.