• 제목/요약/키워드: scale-up technology

검색결과 813건 처리시간 0.03초

Marked effect of Cuscuta on puerarin accumulation in cell cultures of Pueraria tuberosa grown in shake flasks and a bioreactor

  • Goyal, Shaily;Sharma, Varsha;Ramawat, Kishan G.
    • Plant Biotechnology Reports
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    • 제5권2호
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    • pp.121-126
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    • 2011
  • Isoflavonoid production in cell cultures of Pueraria tuberosa as influenced by an angiospermic parasite, Cuscuta reflexa, was studied. During the time course, maximum isoflavonoid content was recorded when Cuscuta elicitor was added on day 15 of culture. Among various concentrations of elicitor tried, $1g\;l^{-1}$ of Cuscuta elicitor was found to be the most effective. The optimized elicitation conditions were used in vessels of varying capacity where maximum yield of ${\sim}91mg\;l^{-1}$ of isoflavonoid was recorded in a 2-l bioreactor which was about 19% higher than the control cultures. In this case, puerarin content increased up to $11mg\;l^{-1}$ which was 580% higher that the value recorded in the control cultures. In the bioreactor, 8 days of elicitation was optimal for the high accumulation of isoflavonoid, giving productivity of ${\sim}4mg\;l^{-1}\;day^{-1}$. The study showed persistent high isoflavonoid yield even during scale-up. Use of a preparation of Cuscuta reflexa as an elicitor is reported for the first time. The increase in isoflavonoid content was elicitor dose-dependent and can be explored to trigger high yields of isoflavonoid/secondary metabolites in production.

저열량 합성가스를 이용한 가압 순산소 연소 시스템의 연소 특성 분석 연구 (Investigation on Combustion Characteristics of Pressurized Oxy-fuel Combustion System using Low Calorific Value Syngas)

  • 김동희;이영재;양원
    • 한국연소학회지
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    • 제21권4호
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    • pp.39-47
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    • 2016
  • The aims of this research were to investigate combustion characteristics of lab-scale pressurized oxy-fuel combustion(POFC) system. In this study, the reactor, 800 mm long, was equipped with co-axial burner. Low calorific value syngas that is composed of mainly CO and $H_2$ was used as fuel whereas pure oxygen was used as an oxidant. Thermal heat input to the reactor varied from 2.6 kW to 6.1 kW. The reactor pressure also increases from atmospheric up to 15 bar. The results show that as the pressure increase, the temperature of reactor decreases on the whole in all cases. A significant temperature drop was observed especially at the bottom section of the reactor that exist flame. In addition, the flame instability increases as the pressure increases. Furthermore $NO_x$ emissions increases from atmospheric up to 2 bar. However beyond 2 bar, $NO_x$ emission reduces as pressure increases. Lastly $NO_2$ ratio in $NO_x$ also increases as pressure increases.

Design and Analysis of Small Walking Robots Utilizing Piezoelectric Benders

  • Park, Jong Man;Song, Chi Hoon;Park, Min Ho
    • 한국전기전자재료학회논문지
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    • 제33권5호
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    • pp.380-385
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    • 2020
  • Over the past decade, small robots have been of particular interest in the engineering field. Among the various types of small robots, biomimetic robots, which mimic animals and insects, have been developed for special activities in areas where humans cannot physically access. The optimal motion of a walking robot can be determined by the characteristics of the traversed surface (e.g., roughness, curvature, slope, materials, etc.). This study proposes three types of piezoelectric structures using different driving mechanisms, depending on the application range of the small walking robots. Dynamic modeling using computer-aided engineering optimized the shape of the robot to maximize its moving characteristics, and the results were also verified through its fabrication and experimentation. Three types of robots, named by their actuator shapes as I, π, & T-shape, were proposed regarding application for small scale ambulatory robots to different terrain conditions. Among these, the T-shaped robots were shown to have a wide range of speeds (from 2 mm/s up to 255 mm/s) and good carrying capacity (up to 10 g at 50 mm/s) through driving experiments. Based on this study, we proposed possible application areas for the three types of walking robot actuators.

제주도민의 119화를 위한 소방의 발전방안 (A Study on Development way of Fire fighting 119 angers of Jeju Islander)

  • 고재문;김태민
    • 한국응급구조학회지
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    • 제7권1호
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    • pp.147-178
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    • 2003
  • In terms of reinforcing the functions and services of rescue 119 and emergency corps, we must review the following considerations : Building up security system along with operational expansion, building up a system for emergency medical treatment, buliding up a comprehensive information management system for rescue and emergency, constructing a provincial safety museum and so forth. For the ways to better the works of rescue 119, we can review the following considerations : Improving the education for fire fighting trainging corps under Jeju Provicial Fire and disaster management department, providing rescue members with more opportunity for clinical practices, enhancing the morale of rescue members, installing a comprehensive briefing room for emergency rescue members, building up medical networks along with reasonable policies for information service, operating the consulting system for rescue 119 and so on. Provide little more superior quality high fire fighting service to jeju islander, and need long-term and elaborate research to correspond in rising fire fighting man-power demand newly and investment. Construction of well-matched disaster administration system is assignment that must hurry in international free city. That jejudo receives time factor about that is received for another thing area's number of persons or equipment when regional special quality large scale or disaster happens is that of course the support receives limitation immediately. Jeju fire fighting services is one story reform, specialization taking into account particular situation of jeju area to grow as sightseeing and center of culture intending international free city, should be upgraded. So, it may do big contribution naturally in jeju international free city phase that coincide jeju islander's social welfare promotion and safety desire.

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코렉스에서 파이넥스로: 포스코의 경로실현형 기술혁신 (From COREX to FINEX: The Case of Path-revealing Innovation in POSCO)

  • 송성수;송위진
    • 기술혁신학회지
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    • 제13권4호
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    • pp.700-716
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    • 2010
  • 이 논문에서는 탈(脫)추격형 기술혁신의 사례로 1990~2007년에 포스코가 용융환원법을 개발한 과정과 그 특정에 대해 분석하였다. 포스코는 차세대 혁신철강기술의 일환으로 용융환원법에 주목했으며, 푀스트와의 협력을 바탕으로 코렉스 공법을 상용화하는 데 성공하였다. 더 나아가 포스코는 분광석을 원료로 사용할 수 있는 파이넥스 공법을 개발하는 작업을 전개했으며, 그것은 모델 플랜트, 파일럿 플랜트, 데모 플랜트, 상용화 설비의 단계를 거쳤다. 포스코는 파이넥스 공법과 관련된 모든 영역의 기술을 개발 혹은 확보하는 데 성공함으로써 기존의 빠른 추종자를 넘어 기술혁신 선도자로 부상하고 있다. 포스코의 용융환원법 개발과정은 적절한 기술선택, 점진적 규모 확대, 나선형 기술개발방식, 상호보완적 기술협력, 과감한 연구개발투자, 중량급 프로젝트 매니저의 존재, 초기 단계의 정부 지원 등과 같은 특성을 보였다. 이러한 포스코의 용융환원법 사례는 기술패러다임 전환기에 이루어진 경로실현형 기술혁신(path-revealing innovation) 에 해당한다.

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Experimental Study on Hydrogen Direct Reduction of Hematite in a Lab Scale Fluidized Bed Reactor by Estimating the Gas Consumption Rate

  • Hasolli, Naim;Jeon, Seong Min;Park, Young Ok;Kim, Yong Ha
    • 청정기술
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    • 제21권2호
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    • pp.96-101
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    • 2015
  • 수소를 환원제로 사용한 산화철의 유동 환원에서, 환원율에 대한 다양한 공정 변수를 통해 산화철의 하나인 적철광의 환원 거동을 면밀히 관찰하였다. 본 연구를 위해 특별히 설계된 실험실 규모의 유동층 장치에서 목적으로 하는 환원 특성에 대한 가스 속도, 환원 시간 및 온도의 최적 값을 평가 하였다. 최적의 환원율을 나타낸 온도는 750 ℃, 환원 시간은 30분이며 이들을 다음의 시험을 위한 시작점으로 매개 변수 값을 설정 하였다. 가장 높은 관심을 갖는 변수들 중 하나는 가스의 소비 원단 위로, 이는 최적의 조건에서 산화철 1톤을 기준하여 90% 이상의 환원율을 달성하기 위해 요구되는 가스의 양을 말한다. 이 매개 변수는 실험실 수준 장치의 스케일 엎에 있어서 중요한 인자이며, 본 연구를 통해 1,500 Nm3/ton-ore가 산화철이 가장 높은 환원율을 갖기 위한 최적의 가스 소비 원단위 임을 확인하였다.

A Study on the Measurement for the Nano Scale Film Formation of Ultra Low Aspect Ratio

  • Jang Siyoul;Kong Hyunsang
    • 한국윤활학회:학술대회논문집
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    • 한국윤활학회 2004년도 학술대회지
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    • pp.283-288
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    • 2004
  • The measurement of ultra low aspect ratio fluid film thickness is very crucial technique both for the verification of lubrication media characteristics and for the clearance design in many precision components such as MEMS, precision bearings and other slideways. Many technologies are applied to the measurement of ultra low aspect ratio fluid film thickness (i.e. elastohydrodynamic lubrication film thickness). In particular, in-situ optical interferometric method has many advantages in making the actual contact behaviors realized with the experimental apparatus. This measurement method also does the monitoring of the surface defects and fractures happening during the contact behavior, which are delicately influenced by the surface conditions such as load, velocity, lubricant media as well as surface roughness. Careful selection of incident lights greatly enhances the fringe resolutions up to $\~1.0$ nanometer scale with digital image processing technology. In this work, it is found that coaxial aligning trichromatic incident light filtering system developed by the author can provide much finer resolution of ultra low aspect ratio fluid film thickness than monochromatic or dichromatic incident lights, because it has much more spectrums of color components to be discriminated according the variations of film thickness. For the measured interferometric images of ultra low aspect ratio fluid film thickness it is shown how the film thickness is finely digitalized and measured in nanometer scale with digital image processing technology and space layer method. The developed measurement system can make it possible to visualize the contact deformations and possible fractures of contacting surface under the repeated loading condition.

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수작농가(水稻作農家)의 적정영농규모계측(適正營農規模計測)에 관(關)한 연구(硏究) -강원도 철원군 평야지역 농가를 중심으로- (A Study on an Estimation of Optimum Rice Farm Size)

  • 김종필;임재환
    • 농업과학연구
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    • 제32권1호
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    • pp.81-94
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    • 2005
  • This study is aimed at giving the basic information for individual farm households to make decisions for optimizing their farm sizes and for the government to implement farm size optimization policies through the identification of combinations among rice production factors in plain areas like Cheolwon district and the suggestion of the optimal farm sizes of individual farmers based on the scale of economy calculated. The data of agricultural production costs of 50 rice farmers in the plain area which is located in Dongsong-eup Cholwon district, Kangwon province were used in the analysis. The 'translog' cost function among various methods which is a flexible function type was adopted to calculate the scale of economy in rice production. Seemingly unrelated regression(SUR) method was used in forecasting functions and processing other statistics by SHAZAM which is one of the computer aid program for quantitative econometric analysis. In conclusion, the long-run average cost(LAC) curve showed 'U-shape' which was different from 'L-type' one which was shown in the previous studies by others. The lowest point of the LAC was 9.764ha and the concerned production cost amounted to 633 Won/kg. Based on these results, it have to be suggested that around 10 ha of paddy is the target size for policy assistances to save costs under the present level of farming practices and technology. The above results show that the rice production costs could be saved up to 10ha in Cheolwon plain area which is a typical paddy field. However, land use, land condition, land ownership and manager's ability which may affect scale of economy should be considered. Furthermore, reasonable management will have to be realized by means of labor saving technology and cost saving management skill like enlargement of farm size of rice.

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개발도상국기업의 기술창출단계 기술혁신: 프로세스 기술개발 사례연구 (Developing Country Firm's Technological Innovation in the Technology Generation Stage: Process Technology Development Case Study)

  • 정기대
    • 기술혁신학회지
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    • 제12권1호
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    • pp.237-264
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    • 2009
  • 선도적으로 기술창출단계의 기술혁신에 성공하여 최초경로로 기술리더가 된 국내기업에 대한 혁신 연구는 새롭게 도전하려는 국내기업과 개발도상국기업에게 시행착오를 줄일 수 있는 시사점을 제공할 수 있다. 그러나 개발도상국기업의 기술창출단계 혁신에 대한 연구가 부족하며, 특히 프로세스혁신에 대한 연구는 제품혁신연구에 비해 더욱 부족한 상황이다. 본 연구는 기술창출단계의 프로세스 기술혁신 프로젝트를 대상으로 하는 탐색적 연구이다. 최초경로로 기술리더가 된 POSCO의 FINEX(파이넥스) 사례에서는 기술창출단계 혁신은 기술내재화단계 고도화의 연장선이라기보다는 높은 위험을 감수하는 최고경영층의 결단에 의해 시도되는 불연속적인 특성이 있으며, 기술창출단계 혁신을 시작하는 개발도상국기업이 일반적으로 초기에 직면하는 원천기술을 개발을 위한 기술역량의 부족은 원천기술을 개발 중인 선발자와의 보완적 기술협력을 통해 극복하였다. 그리고 선진국 경쟁자보다 뒤늦게 기술 개발을 시작하였지만 가장 먼저 상용화단계에 도달할 수 있었던 것은 기술개발 가속화(Speed-up)로 기술개발속도에 영향을 주는 세부요인을 파악하였다.

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극소 광 조형기술을 이용한 3차원 구조물의 제작 (Fabrication of 3D structures using micro-stereolithography technology)

  • 이인환;조동우
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 1997년도 추계학술대회 논문집
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    • pp.1080-1083
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    • 1997
  • Micro-stereolithography is a newly proposed technology as a means that can fabricate 3D micro-structures of free form. It makes a 3D structure by dividing the shape into many slices of relevant thickness along honzontal surfaces, hardening each layer of slice with a laser, and stacking them up to a des~red shape. Scale effect becomes important in this micro-fabrication process, d~fferently from the conventional stereolithography. To realize this micro-stereolithography technology, we developed an equipment using Ar+ laser, xyz stages, controllers and all the optic devices. Using the equipment, a number of micro-structures were successfully fabricated including a winecup of several tens of micrometers.

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