• 천문학회지
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• 제48권5호
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• pp.313-323
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• 2015

Active galactic nuclei (AGN) are known for irregular variability on all time scales, down to intra-day variability with relative variations of a few percent within minutes to hours. On such short timescales, unexplored territory, such as the possible existence of a shortest characteristic time scale of activity and the shape of the high frequency end of AGN power spectra, still exists. We present the results of AGN single-dish fast photometry performed with the Korean VLBI Network (KVN). Observations were done in a “anti-correlated” mode using two antennas, with always at least one antenna pointing at the target. This results in an effective time resolution of less than three minutes. We used all four KVN frequencies, 22, 43, 86, and 129 GHz, in order to trace spectral variability, if any. We were able to derive high-quality light curves for 3C 111, 3C 454.3, and BL Lacertae at 22 and 43 GHz, and for 3C 279 at 86 GHz, between May 2012 and April 2013. We performed a detailed statistical analysis in order to assess the levels of variability and the corresponding upper limits. We found upper limits on flux variability ranging from ~1.6% to ~7.6%. The upper limits on the derived brightness temperatures exceed the inverse Compton limit by three to six orders of magnitude. From our results, plus comparison with data obtained by the University of Michigan Radio Astronomy Observatory, we conclude that we have not detected source-intrinsic variability which would have to occur at sub-per cent levels.

• 콘크리트학회논문집
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• 제25권5호
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• pp.477-484
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• 2013

이 연구에서는 순환골재와 고로슬래그 미분말의 치환율에 따른 강섬유 보강 RC보의 구조성능 향상을 위하여 표준실험체(BSS), 성능개선 실험체로는 순환골재와 고로슬래그 미분말을 치환한 실험체(BRS시리즈), 순환골재와 고로슬래그의 치환율에 강섬유를 보강한 실험체(BSRS시리즈)로 총 11개의 실험체를 1/2축소 제작하여 실험을 수행하였다. 실험을 통하여 얻어진 결과를 비교 분석하여 하중-변위, 파괴형태, 최대내력 등을 규명함으로써 구조성능의 개선정도를 평가하였다. 실험 결과 순환골와 고로슬래그 미분말을 치환한 콘크리트에 강섬유를 보강한 실험체(BSRS시리즈)의 경우 표준실험체(BSS)보다 압축강도는 최대 9%, 최대내력은 1~6%, 연성능력은 각각 1.02~1.13배 증가하는 결과를 나타내었다. 또한, 충분한 연성적인 거동과 안정적인 휨인장 파괴를 나타내었다.

• 한국전자파학회논문지
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• 제15권3호
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• pp.258-264
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• 2004

본 논문에서는 40 ㎓ 대역 MMIC(Monolithic Microwave Intergrated Circuit) 이중평형 star 혼합기를 비아 공정이 있는 GaAs substrate(두께 4 mil)상에서 설계 및 제작, 측정하였다. 이중평형 star 혼합기를 구현하기 위해 발룬회로와 다이오드 설계가 필요했다. 발룬회로는 microstrip과 CPS(Coplanar Strip)를 이용하여 새로운 구조를 제안하여, 2 ㎓ 대역으로 주파수를 낮추어 새로운 구조의 발룬 성능을 PCB로 제작하여 확인한 바 있다. 이를 바탕으로 40 ㎓에서 MMIC 발룬을 설계하였다. 제안된 발룬은 비아 공정이 포함된 MMIC 회로에 적 합하며, 이중평형 혼합기 구현에 쉽게 적용 가능하다는 특징이 있다. 다이오드는 p-HEMT를 사용하는 밀리미터파 대역의 다른 MMIC 회로들과의 호환성을 고려하여, p-HEMT 공정을 기반으로 한 쇼트키 다이오드를 설계하였다. 이를 이용 제안한 발룬회로와 다이오드를 조합하여, 이중평형 star 혼합기를 구현하였다. 혼합기의 측정 결과 LO전력이 18 ㏈m일 때, 변환손실 약 30 ㏈를 얻었다. 이는 p-HEMT의 AlGaAs/InGaAs 층에 의한 다이오드 때문이며, p-HEMT구조에서 AlGaAs층을 식각하여 단일 접합 다이오드를 만들면 혼합기의 성능이 개선될 것으로 예상된다.

• Journal of Periodontal and Implant Science
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• 제27권2호
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• pp.411-424
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• 1997

The purpose of this study was to evaluate in vitro the effects during subgingival calculus removal using Nd:YAG laser. The study group was consisted of 30 teeth with advanced periodontal disease extracted before the start of periodontal therapy. The specimens were divided into 8 different groups : 1) untreated control 2) scaling and root planing only 3) laser treated using 150mJ/pulse, 1sec, 5sec, contact mode 4) laser treated using 200mJ/pulse, 5sec, contact mode 5) laser treated using 150mJ/pulse, 1sec, non-contact mode 6) laser treated using 200mJ/pulse, 5sec, non-contact mode 7) laser treated using l5OmJ/pulse, 1sec, contact mode with water irrigation 8) laser treated using 200mJ/pulse, 5sec, contact mode with water irrigation. All specimens were prepared for evaluation by scanning electron microscopy(SEM). Specimens from Group 2 exhibited a smear layer of scale like texture with parallel instrument tracks resulting from curet use. Specimens treated by contact mode, Group 3 and 4 featured surface changes not observed· in controls such as charring, randomly distributed pitting and crater formation, and melting down of the tooth material and calculus. Specimens treated by noncontact mode, Group 5 and 6 featured similar surface changes observed in contact mode. However, the differences between contact and non-contact groups not significant. Specimens treated by contact mode with water irrigation, Group 7 and 8 featured slight surface change compared to other groups. The results suggested that Nd: YAG laser did not completely remove the subgingival calculus but was possible the application as adjunctive method.

• Steel and Composite Structures
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• 제16권6호
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• pp.611-637
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• 2014

A single plate shear connection, or shear tab, is a very popular shear connection due to its merit in ease of construction and material economy. However, problems in understanding the connection behavior, both in terms of strength and ductility, have been well-documented. Suggestions or design model for single plate connections in AISC Design Manual have been altered several times, with the latest edition settling down to giving designers pre-calculated design strength tables if the connection details agree with given configurations. Results from many full-scale tests and finite element models in the past suggest that shear strength of a bolt group in single plate shear connections might be affected by yield strength of plate material; therefore, this research was aimed to investigate and clarify effects of plate yield strength and thickness on shear strength of the bolt group in the connections, including the validity of using a plate thickness/bolt diameter ratio ($t_p/d_b$) in design, by using finite element models. More than 20 models have been created by using ABAQUS program with 19.0- and 22.2-mm A325N bolts and A36 and Gr.50 plates with various thicknesses. Results demonstrated that increase of plate thickness or plate yield strength, with the $t_p/d_b$ ratio remained intact, could significantly reduce shear strength of the bolt group in the connection as much as 15 percent. Results also confirmed that the $t_p/d_b$ ratio is a valid indicator to be used for guaranteeing strength sufficiency. Because the actual ratio recommended by AISC Design Manual is $t_p/d_b$ + 1.6 (mm) for connections with a number of bolts less than six and plate yield strength in construction is normally higher than the nominal value used in design, it is proposed that shear strength of a bolt group in single plate connections with a number of bolts equal or greater than seven be reduced by 15 percent and the $t_p/d_b$ ratio be limited to 0.500.

• Steel and Composite Structures
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• 제7권2호
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• pp.87-103
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• 2007

This paper presents some of the results from an experimental research project on the behavior of extended end-plate connections subjected to moment conducted at the Structural Laboratory of Jordan University of Science and Technology. Since the connection behavior affects the structural frame response, it must be included in the global analysis and design. In this study, the behavior of six full-scale stiffened and unstiffened cantilever connections of HEA- and IPE-sections has been investigated. Eight high strength bolts were used to connect the extended end-plate to the column flange in each case. Strain gauges were installed inside each of the top six bolts in order to obtain experimentally the actual tension force induced within each bolt. Then the connection behavior is characterized by the tension force in the bolt, extended end-plate behavior, moment-rotation relation, and beam and column strains. Some or all of these characteristics are used by many Standards; therefore, it is essential to predict the global behavior of column-beam connections by their geometrical and mechanical properties. The experimental test results are compared with two theoretical (equal distribution and linear distribution) approaches in order to assess the capabilities and accuracy of the theoretical models. A simple model of the joint is established and the essential parameters to predict its strength and deformational behavior are determined. The equal distribution method reasonably determined the tension forces in the upper two bolts while the linear distribution method underestimated them. The deformation behavior of the tested connections was characterized by separation of the column-flange from the extended end-plate almost down to the level of the upper two bolts of the lower group and below this level the two parts remained in full contact. The neutral axis of the deformed joint is reasonably assumed to pass very close to the line joining the upper two bolts of the lower group. Smooth monotonic moment-rotation relations for the all tested frames were observed.

• Asian Pacific Journal of Cancer Prevention
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• 제16권1호
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• pp.23-29
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• 2015

Background: Current cancer therapy mainly focuses on identifying novel targets crucial for tumorigenesis. The FoxM1 is of preference as an anticancer target, due to its significance in execution of mitosis, cell cycle progression, as well as other signal pathways leading to tumorigenesis. FoxM1 is partially regulated by oncoproteins or tumor suppressors, which are often mutated, lost, or overexpressed in human cancer. Since sustaining proliferating signaling is an important hallmark of cancer, FoxM1 is overexpressed in a series of human malignancies. Alarge-scale gene expression analysis also identified FoxM1 as a differentially-expressed gene in most solid tumors. Furthermore, overexpressed FoxM1 is correlated with the prognosis of cancer patients, as verified in a series of malignancies by Cox regression analysis. Thus, extensive studies have been conducted to explore the roles of FoxM1 in tumorigenesis, making it an attractive target for anticancer therapy. Several antitumor drugs have been reported to target or inhibit FoxM1 expression in different cancers, and down-regulation of FoxM1 also abrogates drug resistance in some cancer cell lines, highlighting a promising future for FoxM1 application in the clinic.

• 대한한의학회지
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• 제22권3호
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• pp.42-50
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• 2001

Objectives : Dysphagia is common and severe problems of acute stroke determining the prognosis of stroke only second to mental change, and results in secondary fatal complications such as aspiration pneumonia, malnutrition, dehydration, etc. Therefore, we were to investigate the clinical characteristics of dysphagia accompanied by acute ischemic stroke. Methods : We selected subjects through clinical notes retrospectively, whose main problems included dysphagia resulted from acute stroke within 72 hours from onset who were admitted to the Internal Medicine Department of Wonkwang Oriental Medicine Hospital from Jan. 2000 to Apr. 2001. We assessed the severity of dysphagia from admission to discharge using a staging method : stage 0 is normal without dysphagia, stage 1 is nearly normal except for intermittent dysphagia, stage 2 is compensated abnormal swallowing requiring adjusted diets or delayed feeding time, stage 3 is uncompensated abnormal swallowing resulted in weight loss down to 10% of initial and daily aspiration, coughing, and vomiting, stage 4 is uncompensated abnormal swallowing resulting in weight loss beyond 10% and recommended for non-oral feeding, and stage 5 is 100% non-oral feeding by L-tube, or gastrostomy or NPO state. Results : Dysphagia was improved statistically significantly from the mean stage of $3.6{\pm}0.29$ on admission to $1.88{\pm}0.32$ on discharge (P<0.05). On average $7.1{\pm}1.48$ days were required for improving more than one stage level. As patients were older and the stage of dysphagia was worse on admission, severity of dysphagia was more difficult to improve (correlation coefficiency was 0.55 and 0.77 respectively, P<0.05). Aspiration pneumonia was complicated in 13 patients of the total 25 at mean dysphagia stage of $3.36{\pm}0.37$. However, any specific values such as lesion size, lesion site, sex, age, past history and NIH Stroke Scale on admission did not affect it (P>0.05). Conclusion : Clinical course of dysphagia was determined about I week from the onset. Aspiration pneumonia was mainly complicated during oral feeding periods. If there were no improvement of dysphagia over 2-3 weeks, then non-oral feeding such as Levin tube or gastrostomy must be considered.

• 대한한방소아과학회지
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• 제14권2호
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• pp.133-140
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• 2000

Purpose : Posterior Neck Pain and Back Pain are common diseases in human daily life. For reducting symptom and treatment of these diseases, many methods have been used and studied until now. The mechanisms of Ceragem Master Heat Bed(R)(Ceragem Co. Seoul, Korea) are infrared-heat therapy from natural nephrite and pressure therapy by up-down movement of natural nephrite ball. Through this study, authors would evaluate the clinical effectiveness of Ceragem Master Heat Bed(CMHB) on relieving posterior neck pain and back pain. Materials and methods : From 12-01-2000 to 01-13-2001, posterior neck pain and back pain patients were selected for experiment group(23patients) and control group(14patients). In both group, Visual Analog Scale(VAS) of pre-treatment stage is above 5 points. Experiment group were cared with acupuncture therapy, buhang therapy and CMHB. Control group were managed with only acupuncture therapy and buhang therapy. They were treated more than three times at least. At pre-treatment and post-treatment stage, we measured VAS for individual patients, and then compared effect of treatment in experiment group and in control group. Statistical analysis was preformed using SAS program. Results : In this study, a mean difference of VAS between pre-treatment and post-treatment stage was large in experiment(CMHB) group more than in control group(p〈0.01). Conclusion : Experiment(CMHB) group was more effective pain relief than control group in the treatment of posterior neck pain and back pain. CMHB was available for stimultaneous application of heat therapy and pressure massage together that gave another effects of mental stability and fatigue recovery. As the results of this study, CMHB could be used as a helpful treatment modality for posterior neck pain and back pain.

• 한국군사과학기술학회지
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• 제20권3호
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• pp.384-392
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• 2017

A linear explosively formed penetrator(LEFP) is a modification of the explosively formed penetrator(EFP). An EFP is axisymmetric and has a dish-shaped liner while LEFP has a rectangular-shaped liner with curved cross section. Upon detonating LEFP forms laterally wide projectile like blade, leaving a long penetration hole on the target. On the other hand, a long-rod tungsten heavy alloy(WHA) penetrator is one of the major threats against most of the ground armored vehicles. In this paper, the feasibility of using an LEFP in protecting against a long-rod WHA penetrator by colliding LEFP into the threat was investigated through a set of numerical simulations. In this study, a scale-down WHA penetrator with length to diameter ratio(L/D) of 10.7 and 7.0 mm diameter was used to represent a long-rod WHA penetrator. LS-DYNA and Multi-Material ALE technique were employed for the simulation. For estimation of the protection effect by LEFP, residual penetration depths into RHA by the threat were compared according to various impact locations against the threat.