• Journal of The Korean Astronomical Society
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• v.48 no.5
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• pp.313-323
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• 2015

Active galactic nuclei (AGN) are known for irregular variability on all time scales, down to intra-day variability with relative variations of a few percent within minutes to hours. On such short timescales, unexplored territory, such as the possible existence of a shortest characteristic time scale of activity and the shape of the high frequency end of AGN power spectra, still exists. We present the results of AGN single-dish fast photometry performed with the Korean VLBI Network (KVN). Observations were done in a “anti-correlated” mode using two antennas, with always at least one antenna pointing at the target. This results in an effective time resolution of less than three minutes. We used all four KVN frequencies, 22, 43, 86, and 129 GHz, in order to trace spectral variability, if any. We were able to derive high-quality light curves for 3C 111, 3C 454.3, and BL Lacertae at 22 and 43 GHz, and for 3C 279 at 86 GHz, between May 2012 and April 2013. We performed a detailed statistical analysis in order to assess the levels of variability and the corresponding upper limits. We found upper limits on flux variability ranging from ~1.6% to ~7.6%. The upper limits on the derived brightness temperatures exceed the inverse Compton limit by three to six orders of magnitude. From our results, plus comparison with data obtained by the University of Michigan Radio Astronomy Observatory, we conclude that we have not detected source-intrinsic variability which would have to occur at sub-per cent levels.

• Journal of the Korea Concrete Institute
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• v.25 no.5
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• pp.477-484
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• 2013

In this study, eleven reinforced concrete beams, ground granulated blast furnace slag, replacing recycled coarse aggregate (BRS series) and recycled coarse aggregate with steel fiber (BSRS series), and standard specimen (BSS) were constructed and tested under monotonic loading. Experimental programs were carried out to improve and evaluate the shear performance of such test specimens, such as the load-displacement, the failure mode and the maximum load carrying capacity. All the specimens were modeled in 1/2 scale-down size. Test results showed that test specimens (BSRS Series) was increased the compressive strength by 9%, the maximum load carrying capacity by 1~6% and the ductility capacity by 1.02~1.13 times in comparison with the standard specimen (BSS). And the specimens (BSRS Series) showed enough ductile behavior and stable flexural failure.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.15 no.3
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• pp.258-264
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• 2004

In this paper, MMIC double balanced star mixer for 40 ㎓ was implemented on GaAs substrate with backside vias. In the design of the MMIC mixer, the design of balun and diode was required. A novel balun structure using microstrip to CPS was presented. The 40 ㎓ balun was designed based on the design experience of the scale-down balun by 2 ㎓. The balun may be suitable for fabrication in MMIC process with backside via and can easily be applied for DBM(Double Balanced Mixer). A Schottky diode was designed and implemented using p-HEMT process considering the compatability with other high frequency MMIC's fabricated on p-HEMT base process. Finally, the double balanced star mixer was fabricated using the balun and the p=HEMP Schottky diode. The measured performance of mixer shows 30 ㏈ conversion loss at 18 ㏈m LO power. This insufficient performance is caused by the unwanted diode at AlGaAs junction in vertical structure of p-HEMT. If the p-HEMT's gate is recessed to AlGaAs layer, and so the diode is eliminated, the mixer's performances will be improved.

• Journal of Periodontal and Implant Science
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• v.27 no.2
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• pp.411-424
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• 1997

The purpose of this study was to evaluate in vitro the effects during subgingival calculus removal using Nd:YAG laser. The study group was consisted of 30 teeth with advanced periodontal disease extracted before the start of periodontal therapy. The specimens were divided into 8 different groups : 1) untreated control 2) scaling and root planing only 3) laser treated using 150mJ/pulse, 1sec, 5sec, contact mode 4) laser treated using 200mJ/pulse, 5sec, contact mode 5) laser treated using 150mJ/pulse, 1sec, non-contact mode 6) laser treated using 200mJ/pulse, 5sec, non-contact mode 7) laser treated using l5OmJ/pulse, 1sec, contact mode with water irrigation 8) laser treated using 200mJ/pulse, 5sec, contact mode with water irrigation. All specimens were prepared for evaluation by scanning electron microscopy(SEM). Specimens from Group 2 exhibited a smear layer of scale like texture with parallel instrument tracks resulting from curet use. Specimens treated by contact mode, Group 3 and 4 featured surface changes not observed· in controls such as charring, randomly distributed pitting and crater formation, and melting down of the tooth material and calculus. Specimens treated by noncontact mode, Group 5 and 6 featured similar surface changes observed in contact mode. However, the differences between contact and non-contact groups not significant. Specimens treated by contact mode with water irrigation, Group 7 and 8 featured slight surface change compared to other groups. The results suggested that Nd: YAG laser did not completely remove the subgingival calculus but was possible the application as adjunctive method.

• Steel and Composite Structures
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• v.16 no.6
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• pp.611-637
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• 2014

A single plate shear connection, or shear tab, is a very popular shear connection due to its merit in ease of construction and material economy. However, problems in understanding the connection behavior, both in terms of strength and ductility, have been well-documented. Suggestions or design model for single plate connections in AISC Design Manual have been altered several times, with the latest edition settling down to giving designers pre-calculated design strength tables if the connection details agree with given configurations. Results from many full-scale tests and finite element models in the past suggest that shear strength of a bolt group in single plate shear connections might be affected by yield strength of plate material; therefore, this research was aimed to investigate and clarify effects of plate yield strength and thickness on shear strength of the bolt group in the connections, including the validity of using a plate thickness/bolt diameter ratio ($t_p/d_b$) in design, by using finite element models. More than 20 models have been created by using ABAQUS program with 19.0- and 22.2-mm A325N bolts and A36 and Gr.50 plates with various thicknesses. Results demonstrated that increase of plate thickness or plate yield strength, with the $t_p/d_b$ ratio remained intact, could significantly reduce shear strength of the bolt group in the connection as much as 15 percent. Results also confirmed that the $t_p/d_b$ ratio is a valid indicator to be used for guaranteeing strength sufficiency. Because the actual ratio recommended by AISC Design Manual is $t_p/d_b$ + 1.6 (mm) for connections with a number of bolts less than six and plate yield strength in construction is normally higher than the nominal value used in design, it is proposed that shear strength of a bolt group in single plate connections with a number of bolts equal or greater than seven be reduced by 15 percent and the $t_p/d_b$ ratio be limited to 0.500.

• Steel and Composite Structures
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• v.7 no.2
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• pp.87-103
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• 2007

This paper presents some of the results from an experimental research project on the behavior of extended end-plate connections subjected to moment conducted at the Structural Laboratory of Jordan University of Science and Technology. Since the connection behavior affects the structural frame response, it must be included in the global analysis and design. In this study, the behavior of six full-scale stiffened and unstiffened cantilever connections of HEA- and IPE-sections has been investigated. Eight high strength bolts were used to connect the extended end-plate to the column flange in each case. Strain gauges were installed inside each of the top six bolts in order to obtain experimentally the actual tension force induced within each bolt. Then the connection behavior is characterized by the tension force in the bolt, extended end-plate behavior, moment-rotation relation, and beam and column strains. Some or all of these characteristics are used by many Standards; therefore, it is essential to predict the global behavior of column-beam connections by their geometrical and mechanical properties. The experimental test results are compared with two theoretical (equal distribution and linear distribution) approaches in order to assess the capabilities and accuracy of the theoretical models. A simple model of the joint is established and the essential parameters to predict its strength and deformational behavior are determined. The equal distribution method reasonably determined the tension forces in the upper two bolts while the linear distribution method underestimated them. The deformation behavior of the tested connections was characterized by separation of the column-flange from the extended end-plate almost down to the level of the upper two bolts of the lower group and below this level the two parts remained in full contact. The neutral axis of the deformed joint is reasonably assumed to pass very close to the line joining the upper two bolts of the lower group. Smooth monotonic moment-rotation relations for the all tested frames were observed.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.1
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• pp.23-29
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• 2015

Background: Current cancer therapy mainly focuses on identifying novel targets crucial for tumorigenesis. The FoxM1 is of preference as an anticancer target, due to its significance in execution of mitosis, cell cycle progression, as well as other signal pathways leading to tumorigenesis. FoxM1 is partially regulated by oncoproteins or tumor suppressors, which are often mutated, lost, or overexpressed in human cancer. Since sustaining proliferating signaling is an important hallmark of cancer, FoxM1 is overexpressed in a series of human malignancies. Alarge-scale gene expression analysis also identified FoxM1 as a differentially-expressed gene in most solid tumors. Furthermore, overexpressed FoxM1 is correlated with the prognosis of cancer patients, as verified in a series of malignancies by Cox regression analysis. Thus, extensive studies have been conducted to explore the roles of FoxM1 in tumorigenesis, making it an attractive target for anticancer therapy. Several antitumor drugs have been reported to target or inhibit FoxM1 expression in different cancers, and down-regulation of FoxM1 also abrogates drug resistance in some cancer cell lines, highlighting a promising future for FoxM1 application in the clinic.

• The Journal of Korean Medicine
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• v.22 no.3
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• pp.42-50
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• 2001

Objectives : Dysphagia is common and severe problems of acute stroke determining the prognosis of stroke only second to mental change, and results in secondary fatal complications such as aspiration pneumonia, malnutrition, dehydration, etc. Therefore, we were to investigate the clinical characteristics of dysphagia accompanied by acute ischemic stroke. Methods : We selected subjects through clinical notes retrospectively, whose main problems included dysphagia resulted from acute stroke within 72 hours from onset who were admitted to the Internal Medicine Department of Wonkwang Oriental Medicine Hospital from Jan. 2000 to Apr. 2001. We assessed the severity of dysphagia from admission to discharge using a staging method : stage 0 is normal without dysphagia, stage 1 is nearly normal except for intermittent dysphagia, stage 2 is compensated abnormal swallowing requiring adjusted diets or delayed feeding time, stage 3 is uncompensated abnormal swallowing resulted in weight loss down to 10% of initial and daily aspiration, coughing, and vomiting, stage 4 is uncompensated abnormal swallowing resulting in weight loss beyond 10% and recommended for non-oral feeding, and stage 5 is 100% non-oral feeding by L-tube, or gastrostomy or NPO state. Results : Dysphagia was improved statistically significantly from the mean stage of $3.6{\pm}0.29$ on admission to $1.88{\pm}0.32$ on discharge (P<0.05). On average $7.1{\pm}1.48$ days were required for improving more than one stage level. As patients were older and the stage of dysphagia was worse on admission, severity of dysphagia was more difficult to improve (correlation coefficiency was 0.55 and 0.77 respectively, P<0.05). Aspiration pneumonia was complicated in 13 patients of the total 25 at mean dysphagia stage of $3.36{\pm}0.37$. However, any specific values such as lesion size, lesion site, sex, age, past history and NIH Stroke Scale on admission did not affect it (P>0.05). Conclusion : Clinical course of dysphagia was determined about I week from the onset. Aspiration pneumonia was mainly complicated during oral feeding periods. If there were no improvement of dysphagia over 2-3 weeks, then non-oral feeding such as Levin tube or gastrostomy must be considered.

• The Journal of Pediatrics of Korean Medicine
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• v.14 no.2
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• pp.133-140
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• 2000

Purpose : Posterior Neck Pain and Back Pain are common diseases in human daily life. For reducting symptom and treatment of these diseases, many methods have been used and studied until now. The mechanisms of Ceragem Master Heat Bed(R)(Ceragem Co. Seoul, Korea) are infrared-heat therapy from natural nephrite and pressure therapy by up-down movement of natural nephrite ball. Through this study, authors would evaluate the clinical effectiveness of Ceragem Master Heat Bed(CMHB) on relieving posterior neck pain and back pain. Materials and methods : From 12-01-2000 to 01-13-2001, posterior neck pain and back pain patients were selected for experiment group(23patients) and control group(14patients). In both group, Visual Analog Scale(VAS) of pre-treatment stage is above 5 points. Experiment group were cared with acupuncture therapy, buhang therapy and CMHB. Control group were managed with only acupuncture therapy and buhang therapy. They were treated more than three times at least. At pre-treatment and post-treatment stage, we measured VAS for individual patients, and then compared effect of treatment in experiment group and in control group. Statistical analysis was preformed using SAS program. Results : In this study, a mean difference of VAS between pre-treatment and post-treatment stage was large in experiment(CMHB) group more than in control group(p〈0.01). Conclusion : Experiment(CMHB) group was more effective pain relief than control group in the treatment of posterior neck pain and back pain. CMHB was available for stimultaneous application of heat therapy and pressure massage together that gave another effects of mental stability and fatigue recovery. As the results of this study, CMHB could be used as a helpful treatment modality for posterior neck pain and back pain.

• Journal of the Korea Institute of Military Science and Technology
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• v.20 no.3
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• pp.384-392
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• 2017

A linear explosively formed penetrator(LEFP) is a modification of the explosively formed penetrator(EFP). An EFP is axisymmetric and has a dish-shaped liner while LEFP has a rectangular-shaped liner with curved cross section. Upon detonating LEFP forms laterally wide projectile like blade, leaving a long penetration hole on the target. On the other hand, a long-rod tungsten heavy alloy(WHA) penetrator is one of the major threats against most of the ground armored vehicles. In this paper, the feasibility of using an LEFP in protecting against a long-rod WHA penetrator by colliding LEFP into the threat was investigated through a set of numerical simulations. In this study, a scale-down WHA penetrator with length to diameter ratio(L/D) of 10.7 and 7.0 mm diameter was used to represent a long-rod WHA penetrator. LS-DYNA and Multi-Material ALE technique were employed for the simulation. For estimation of the protection effect by LEFP, residual penetration depths into RHA by the threat were compared according to various impact locations against the threat.