• Title/Summary/Keyword: sarcopenia

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Measurement of Uncertainty Using Standardized Protocol of Hand Grip Strength Measurement in Patients with Sarcopenia

  • Ha, Yong-Chan;Yoo, Jun-Il;Park, Young-Jin;Lee, Chang Han;Park, Ki-Soo
    • Journal of Bone Metabolism
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    • v.25 no.4
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    • pp.243-249
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    • 2018
  • Background: The aim of this study was to determine the accuracy and error range of hand grip strength measurement using various methods. Methods: Methods used for measurement of hand grip strength in 34 epidemiologic studies on sarcopenia were analyzed. Maximum grip strength was measured in a sitting position with the elbow flexed at 90 degrees, the shoulder in 0 degrees flexion, and the wrist in neutral position (0 degrees). Maximum grip strength in standing position was measured with the shoulder in 180 degrees flexion, the elbow fully extended, and the wrist in neutral position (0 degrees). Three measurements were taken on each side at 30 sec intervals. The uncertainty of measurement was calculated. Results: The combined uncertainty in sitting position on the right and left sides was 1.14% and 0.38%, respectively, and the combined uncertainty in standing position on the right and left sides was 0.35 and 1.20, respectively. The expanded uncertainty in sitting position on the right and left sides was 2.28 and 0.79, respectively, and the expanded uncertainty in standing position on the right and left sides was 0.71 and 2.41, respectively (k=2). Conclusions: Uncertainty of hand grip strength measurement was identified in this study, and a significant difference was observed between measurement. For more precise diagnosis of sarcopenia, dynamometers need to be corrected to overcome uncertainty.

The effects of 12-weeks complex training using swiss ball and elastic band on senior fitness and sarcopenia index in elderly women (스위스 볼과 탄성 밴드를 이용한 저항성운동이 여성 노인의 체력 및 근감소증 지표에 미치는 영향)

  • Park, Woo-Young
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.6
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    • pp.1465-1474
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    • 2020
  • The purpose of this study is the effects of 12 weeks complex training using swiss ball and elastic band on senior fitness and sarcopenia index in elderly women. The subject of this study was classified into exercise group (n=13) and control group (n=14). EG were carrier exercise program with swiss-ball and elastic band by 3 times a week, 3sets, RPE 11-13, and 60 minute. Test variables of among this study, senior fitness which is muscle strength, endurance, flexibility and dynamic balance and age-related sarcopenia index were muscle strength, muscle mass and short physical performance battery (SPPB). The results of this study were not significantly improvement at muscle strength, cardiopulmonary and flexibility but dynamic balance was significantly difference. And SPPB were significantly difference. In conclusion, the complex whole body training had positive effects on dynamic balance and SPPB of the elderly women.

Effect of Pu'er tea extract on C2C12 myoblast differentiation (보이차 열수 추출물의 근아세포 근분화에 미치는 영향)

  • Lee, Hyoseong;Choi, Sunkyung;Lee, Boyeong;Kim, Eunmi;Lee, Woonghee;Han, Hyosang;Kim, Keekwang
    • Journal of Digital Convergence
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    • v.18 no.12
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    • pp.585-594
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    • 2020
  • At present, aging-related degenerative muscle diseases are considered a serious problem. However, the drug effect on the treatment and prevention of sarcopenia has not been investigated. The purpose of this study was to evaluate the value of extract of Pu'er tea as a remedy to alleviate the symptoms of sarcopenia. Pu'er tea extracts showed excellent radical scavenging ability. The expression of Myh3 was promoted and myotube formation also was increased by treatment of Pu'er tea extracts. These results suggest that Pu'er tea is a natural substance that promotes myogenesis, and is valuable as a material for pharmaceutical research on the prevention and treatment of various muscle diseases, including sarcopenia. And It is necessary to confirm specific indicator substances of puer tea and further study on this.

Relationship Between Muscle Mass and Usual Walking Speed Mediated by Muscle Strength, Respiration and Depression in Elderly Female

  • Yun-jeong Baek;Chung-hwi Yi;Oh-yun Kwon;Sang-hyun Cho
    • Physical Therapy Korea
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    • v.30 no.3
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    • pp.202-210
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    • 2023
  • Background: The elderly population is increasing rapidly worldwide. Muscle mass, usual walking speed (UWS), knee extension strength (KES), hand grip strength (HGS), peak expiratory flow (PEF), and depression is used for sarcopenia diagnosis. All four of these factors (KES, HGS, PEF, and depression) correlated with UWS and also to muscle mass. But, many studies have suggested that no correlation exists between muscle mass and UWS. Objects: This study aimed: 1) to investigate whether muscle mass reduction affected UWS, as mediated by KES, HGS, PEF and depression, and 2) to explored whether significant changes in these mediators varied by the body segment in which muscle mass evaluated in elderly female aged 65-80 years. Methods: A total of 100 female aged 65-80 years were surveyed. Muscle mass was measured by body segment (upper and lower segment), and KES, HGS, PEF, depression, and UWS were also assessed. Median analyses were progressed in IBM SPSS software (ver. 23.0, IBM Co.) using a downloaded INDIRECT macro. Results: The direct effect of the KES and PEF were significant, and the indirect effect of KES and PEF were not significant. Thus, KES and PEF served as full mediators of the effect of muscle mass on UWS. Regardless of bodily region, KES and PEF combined with muscle mass were significant mediators of UWS, with similar indirect effect sizes. Conclusion: KES and PEF are the only mediators regardless of body part. Therefore, mediating the KES and PEF may prevent sarcopenia progression in elderly female. Also, sarcopenia can be readily assessed by evaluating either the upper or lower body; it is not necessary to measure total muscle mass.

Pilot Study - Development of Sit-To-Stand and Stand-To-Sit Muscle-Assisted Wearable Robot Algorithms in Elderly Patients with Hip Angle and Angular Velocity (Pilot Study - 고관절 각도 및 각속도 기반 기립(Sit-To-Stand) 및 착석(Stand-To-Sit) 근력 지원 웨어러블 로봇 알고리즘 개발)

  • Yonghyun Lee;Jintak Choi;Dongbin Shin;Yeonghoon Ji;Hyeyeon Jang;Changsoo Han;Yeonjoon Lee
    • The Journal of Korea Robotics Society
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    • v.18 no.4
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    • pp.385-391
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    • 2023
  • In the elderly population, sarcopenia occurs due to physical aging, leading to movement restrictions and loss of function. This results in dependence on daily activities and limitations in participation, ultimately decreasing the overall quality of life. In this study, we propose an algorithm designed to enable patients with sarcopenia to perform sit-to-stand and stand-to-sit movements seamlessly in their daily lives. The algorithm incorporates a wearable robot for muscle support and includes algorithms for standing and seated muscle strength support. To validate the algorithm's performance, EMG sensors were attached to the Rectus Femoris and Biceps Femoris muscles. The participants underwent two scenarios: one without wearing the device and one with the device providing muscle strength support, performing sit-to-stand and stand-to-sit motions for one minute in each case. The results showed a 16% increase in the EMG peak value of the Rectus Femoris muscle during standing motion (p=0.009). On the right side, there was a roughly 20% decrease (p=0.018) during standing and a 21% decrease (p=0.014) during sitting motion. In the future, we aim to gather additional data to further refine the algorithm. Our goal is to develop an optimal muscle strength support algorithm based on this data, making it applicable for real-life use by patients with sarcopenia.

Impact of sarcopenia on biliary drainage during neoadjuvant therapy for pancreatic cancer

  • Kunio Kataoka;Eizaburo Ohno;Takuya Ishikawa;Kentaro Yamao;Yasuyuki Mizutani;Tadashi Iida;Hideki Takami;Osamu Maeda;Junpei Yamaguchi;Yukihiro Yokoyama;Tomoki Ebata;Yasuhiro Kodera;Hiroki Kawashima
    • Clinical Endoscopy
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    • v.57 no.1
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    • pp.112-121
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    • 2024
  • Background/Aims: Since the usefulness of neoadjuvant chemo(radiation) therapy (NAT) for pancreatic cancer has been demonstrated, recurrent biliary obstruction (RBO) in patients with pancreatic cancer with a fully covered self-expandable metal stent (FCSEMS) during NAT is expected to increase. This study investigated the impact of sarcopenia on RBO in this setting. Methods: Patients were divided into normal and low skeletal muscle index (SMI) groups and retrospectively analyzed. Patient characteristics, overall survival, time to RBO (TRBO), stent-related adverse events, and postoperative complications were compared between the two groups. A Cox proportional hazard model was used to identify the risk factors for short TRBO. Results: A few significant differences were observed in patient characteristics, overall survival, stent-related adverse events, and postoperative complications between 38 patients in the normal SMI group and 17 in the low SMI group. The median TRBO was not reached in the normal SMI group and was 112 days in the low SMI group (p=0.004). In multivariate analysis, low SMI was the only risk factor for short TRBO, with a hazard ratio of 5.707 (95% confidence interval, 1.148-28.381; p=0.033). Conclusions: Sarcopenia was identified as an independent risk factor for RBO in patients with pancreatic cancer with FCSEMS during NAT.

Nutrition and Psychosocial Factors were associated with Possible Sarcopenia in the Rural Elderly (농촌지역 주민의 영양결핍 및 사회심리적 요인과 근감소증 가능군과의 관련성)

  • Kim, Bokyoung;Lee, Gyeong-Ye;Seo, Ae-Rim;Kim, Mi-Ji;Seo, Sung-Hyo;Park, Ki-Soo
    • Journal of agricultural medicine and community health
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    • v.47 no.2
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    • pp.90-98
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    • 2022
  • Objective: This study aimed to provide basic data for preventing and managing sarcopenia by identifying the relationship between sarcopenia, malnutrition, and psychosocial factors among the elderly in the community. Methods: The study included 1,019 subjects aged 60 and over. "Possible sarcopenia" was defined by low handgrip strength with or without reduced physical performance. Nutrition was evaluated according to the mini nutrition assessment (MNA), and the psychosocial factors examined were self-efficacy, social isolation, fear of falling, and social capital (trust and participation). A logistic regression analysis was also performed on the relationship between risk of malnutrition, psychosocial factors, and sarcopenia. Results: MNA was significantly associated with social participation (OR = 1.747, p <0.001), fear of falling (OR = 2.905, p <0.001), and self-efficacy (high/low, OR = 0.654, p = 0.011). In model 3, which included both MNA and psychosocial factors, sarcopenia was significantly associated with MNA (OR = 2.529, p <0.001) and fear of falling (OR = 1.544, p = 0.045). Compared with the low self-efficacy group, the high group (OR = 0.589, p = 0.009) was significant. The factors related to possible sarcopenia include risk of malnutrition, fear of falls, and low self-efficacy. Conclusion: It will be necessary to improve self-efficacy so that individuals feel they can do activities of daily living themselves and to reduce their fear of falling through muscle strength and balance exercises. Finally, it is also necessary to increase regular participation in community social activities.

Therapeutic potential of eccentric exercises for age-related muscle atrophy

  • Lim, Jae-Young
    • Integrative Medicine Research
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    • v.5 no.3
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    • pp.176-181
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    • 2016
  • Recent studies have focused on evidence-based interventions to prevent mobility decline and enhance physical performance in older adults. Several modalities, in addition to traditional strengthening programs, have been designed to manage age-related functional decline more effectively. In this study, we reviewed the current relevant literatures to assess the therapeutic potential of eccentric exercises for age-related muscle atrophy (sarcopenia). Age-related changes in human skeletal muscle, and their relationship with physical performance, are discussed with reference to in vitro physiologic and human biomechanics studies. An overview of issues relevant to sarcopenia is provided in the context of the recent consensus on the diagnosis and management of the condition. A decline in mobility among the aging population is closely linked with changes in the muscle force-velocity relationship. Interventions based specifically on increasing velocity and eccentric strength can improve function more effectively compared with traditional strengthening programs. Eccentric strengthening programs are introduced as a specific method for improving both muscle force and velocity. To be more effective, exercise interventions for older adults should focus on enhancing the muscle force-velocity relationship. Exercises that can be performed easily, and that utilize eccentric strength (which is relatively spared during the aging process), are needed to improve both muscle force and velocity.

Proposal of Muscular Strength Improvement Application Design for the Elderly : Focusing on the Case of S city (노인층의 근력향상 애플리케이션을 위한 디자인 제안 : S시 사례를 중심으로)

  • Cho, Yeong Ran;Choi, Min Joo;Paik, Jin Kyung
    • Journal of Korea Multimedia Society
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    • v.25 no.7
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    • pp.953-963
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    • 2022
  • We suggest the development of a mobile muscular savings account application as a more effective and consistent strategy to avoid sarcopenia, one of the elderly diseases, based on the researcher's experience conducting a handwritten 'muscle saving account' in the S city of the metropolitan area. The analysis of currently existent healthcare-related applications shows that muscle strength improvement and maintenance applications are needed to improve easy use and access without burden for elderly users because there are many functions, and it can be difficult for the elderly to use the application. A survey of participants who used handwritten 'muscle savings accounts' was conducted before the design development to measure user satisfaction. Based on this, the suggested application's design is similar to the handwritten type, functionalities are modified for easy usage by the elderly, and information is intuitively comprehended and presented properly using color contrast and Sans serif font. We plan to conduct a survey of the elderly who did not participate in the project as part of follow-up research, and afterward continue the research on the development of customized applications optimized for the prevention of sarcopenia in the elderly for muscle strength improvement and maintenance based on the results.

Effects of Blood Flow Restriction Exercise on Leg Muscle Thickness and Balance in Elderly Women with Sarcopenia

  • Park, Jae-Chul;Mun, Dal-ju;Choi, Seok-Ju
    • PNF and Movement
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    • v.20 no.1
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    • pp.1-8
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    • 2022
  • Purpose: The purpose of this study was to investigate the effect of blood flow restriction bridge exercise on leg muscle thickness and balance. In addition, it is to promote blood flow restriction exercise as the basis for early prevention, diagnosis, and treatment of sarcopenia in clinical practice. Methods: Twenty elderly women aged 65 years or older were selected to participate in this study. The subjects were divided into two groups of 10: one with blood flow restriction with bridge exercise (BFRG) and the other with bridge exercise alone (BG). As for the exercise method, the thickness of rectus femoris and vastus medialis and Berg balance scale were investigated by intervention for 30 minutes a day, 3 times a week, for a total of 6 weeks. Results: There was significant difference in the thickness of the rectus femoris and vastus medial and within-group changes in the Berg balance scale (p <0.05) before and after the experiment in the BFRG and BG groups (p<0.05). There was a significant difference in change between the two groups (p <0.05). Conclusion: There was a significant difference in the intragroup change of the Berg balance scale in the BFRG before and after the experiment, but there was no significant difference in the BG, and there was no significant difference in the change between the two groups.