• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2571-2576
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• 2014

Background: Published studies on the association between the exonuclease 1 (EXO1) Glu589Lys polymorphism and cancer susceptibility have yielded conflicting results. Thus, a meta-analysis of published studies was performed to assess the possible association. Materials and Methods: All eligible case-control studies published up to January 2013 on the association between the EXO1 Glu589Lys polymorphism and cancer susceptibility were identified by searching PubMed, Web of Science, Science Direct and hand search. Either fixed-effect or random-effect models were used to calculate pooled odds ratios (ORs) with 95% confidence intervals (CIs) using the Comprehensive Meta-Analysis software version 2.2. Results: A total of 4,391 cancer cases and 4,339 controls from 10 studies were included. Overall, no significant association between the EXO1 Glu589Lys polymorphism and cancer susceptibility was observed in either genetic model. However; in subgroup analyses by cancer type, a significant association between EXO1 Glu589Lys and lung cancer risk was found (Lys vs Glu: OR=1.23, 95%CI=1.07-1.41, $p_{heterogeneity}$=0.05). Further, subgroup analysis by ethnicity indicated that there was a statistically increased cancer risk in Asians (Lys vs Glu: OR=1.42, 95%CI=1.30-1.55, $p_{heterogeneity}$=0.07; Lys/Lys vs Glu/Glu: OR=1.93, 95%CI=1.20-3.12, $p_{heterogeneity}$=0.01; Lys/Lys+Glu/Lys vs Glu/Glu: OR=1.52, 95%CI=1.37-1.68, $p_{heterogeneity}$=0.42; Lys/Lys vs Glu/Lys+Glu/Glu: OR=1.68, 95%CI=1.07-2.65, $p_{heterogeneity}$=0.02). However, significant association was absent in Caucasians. Conclusions: This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups. Additional well-designed studies with larger sample size focusing on different ethnicities and cancer types are needed to confirm these findings.

• Asian Pacific Journal of Cancer Prevention
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• 제13권10호
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• pp.4943-4946
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• 2012

Studies have reported an association between the TERT rs2736098 single nucleotide polymorphism (SNP) and cancer susceptibility, but the results remain inconclusive. Toprovide a more precise estimation of the relationship, a meta-analysis of 8 published studies including 8,070 cases and 10,239 controls was performed. Stratification by sample size, genotyping method, source of controls and ethnicity were used to explore the source of heterogeneity. In the overall analysis, no significant association was found between the TERT rs2736098 polymorphism and cancer risk. However, the result showed the rs2736098 was significantly associated with an increased cancer risk and the heterogeneity was effectively decreased for homozygote comparison by removal of two studies: OR = 1.337 (95% CI = 1.183-1.511; Pheterogeneity = 0.087). In the subgroup analysis by ethnicity, a significantly increased risk of cancers was found among Asians (OR = 1.413, 95% CI = 1.187-1.683 for AA versus GG). Our meta-analysis did not show that the TERT rs2736098 plays an important role in cancer risk. More studies with larger sample size and well-matched controls are needed to confirm the findings.

• 노동경제논집
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• 제36권2호
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• pp.1-36
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• 2013

본 연구는 임금함수 추정으로부터 얻어진 잔차, 즉 보이지 않는 이질성이 자영업 선택에 어떠한 영향을 미치는지를 살펴본다. Joona and Wadensjo(2013)에 따라 이 잔차를 개인 능력의 대리변수로 간주하고, 과연 능력이 뛰어난 사람이 자영업자가 되는지, 아니면 능력이 낮은 사람이 자영업을 선택하는지를 한국노동패널 1-11차를 이용하여 검증한다. 전체 근로자를 대상으로 할 때 능력의 양극에 있는 사람들이 상대적으로 자영업 진입확률이 높지만, 남녀를 구분할 경우 이러한 U자형의 관계는 존재하지 않으며, 남성의 경우에는 능력이 낮은 사람이, 여성의 경우에는 능력이 높은 사람이 자영업으로 진입한다는 것을 발견하였다. 또한 1998-2008년 사이 능력과 자영업 진입과의 관계에 변화가 있었으며, 능력이 높은 사람이 대체로 자영업 성과도 좋다는 것을 확인하였다.

• 한국멀티미디어학회논문지
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• 제20권11호
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• pp.1776-1784
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• 2017

There are two types of WSN(wireless sensor networks) in terms of sensor node's capability, that is, homogeneous or heterogeneous WSN. Even though the latter has better performance than the former, it requires some overhead for deploying nodes or clustering the network. In this paper, we propose a new scheme, called VHS(Virtual Heterogenous Sensor-Network), which uses a homogeneous WSN regarding energy in a heterogeneous way. The proposed scheme's performance has been evaluated and compared with other homogeneous schemes by simulation. The results are shown to be better than the other existing homogeneous schemes used in a sample sensor network application.

• International Journal of Advanced Culture Technology
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• 제9권1호
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• pp.1-6
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• 2021

This study aims to test the relationship between the change in population size and population composition and crime changes. The analytical model includes variables representing changes in population size and population composition, three dependent variables for crime changes, and three control variables. Changes in popuvpdllation size and population composition are measured by indicators such as population size, gender, age groups, and immigrants and foreign workers, and crime changes by felonious, burglary, and violent crime volumes. The sample includes 154 cities and counties in South Korea, and the sample period is from 2010 to 2017. As a result of the analysis, I examine that the decrease in the number of young and men are likely to lead to a decline in felonious and violent crimes, but a high rate of the elderly and the increasing racial heterogeneity are likely to accelerate the fear and worries about crimes.

• 한국수자원학회논문집
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• 제51권5호
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• pp.383-393
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• 2018

지역빈도해석은 대상 지점과 수문학적 동질성을 만족하는 주변 지점을 하나의 지역으로 보고 빈도해석을 수행하는 방법이다. 따라서 동질한 지역의 구분은 지역빈도해석에 있어서 가장 중요한 가정이라고 할 수 있다. 이에 본 연구에서는 인공신경망 기법중 하나인 자기조직화지도(self-organizing map, SOM) 기법을 활용하여 강우 지역빈도해석을 위한 동질 강수 지역을 구분하였다. 지역구분 인자로는 지형 정보와 시 단위 강우 자료를 활용하였다. 최적 SOM 지도 구성을 위해 정량적 오차와 위상관계 오차를 활용하였다. 그 결과 $7{\times}6$ 배열의 42개의 노드를 갖는 모형을 선정하였고 최종적으로 강우 지역빈도해석을 위해 6개의 군집으로 구분하였다. 동질성 검토 결과 6개의 군집 모두 동질한 지역으로 나타났으며 기존의 유사하게 구분된 지역들과 이질성 척도를 비교하였을 때 좀 더 안정적인 지역 구분결과를 나타내는 것을 확인하였다.

• Journal of Ecology and Environment
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• 제32권2호
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• pp.67-73
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• 2009

Soil $CO_2$ efflux can vary markedly in magnitude over both time and space, and understanding this variation is crucial for the correct measurement of $CO_2$ efflux in ecological studies. Although considerable research has quantified temporal variability in this flux, comparatively little effort has focused on its spatial variability. To account for spatial heterogeneity, we must be able to determine the number of sampling points required to adequately estimate soil $CO_2$ efflux in a target ecosystem. In this paper, we report the results of a study of the number of sampling points required for estimating soil $CO_2$ efflux using a closed-dynamic chamber in young and old Japanese cedar plantations in central Japan. The spatial heterogeneity in soil $CO_2$ efflux was significantly higher in the mature plantation than in the young stand. In the young plantation, 95% of samples of 9 randomly-chosen flux measurements from a population of 16 measurements made using 72-$cm^2$ chambers produced flux estimates within 20% of the full-population mean. In the mature plantation, 20 sampling points are required to achieve means within $\pm$ 20% of the full-population mean (15 measurements) for 95% of the sample dates. Variation in soil temperature and moisture could not explain the observed spatial variation in soil $CO_2$ efflux, even though both parameters are a good predictor of temporal variation in $CO_2$ efflux. Our results and those of previous studies suggest that, on average, approximately 46 sampling points are required to estimate the mean and variance of soil $CO_2$ flux in temperate and boreal forests to a precision of $\pm$ 10% at the 95% confidence level, and 12 points are required to achieve a precision of $\pm$ 20%.

• KSTLE International Journal
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• 제1권2호
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• pp.69-75
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• 2000

The paper compares topography, phase contrast and force spectroscopy in atomic force microscopy data for evaluating the microheterogeneity of surface layer. The worn surface of ion-plated TiN coating was measured using both a laboratory-built and a commercial AFM. The results of analysis revealed structural and micromechanical heterogeneity of the worn surfaces. We demonstrated that the phase image allows relatively qualitative estimation of elastic modulus of the sample surface. The tribolayer formed in the worn surface possessed much lower stiffness than the original coating. It is shown that the most stable phase imaging is provided with a stiff cantilever. In this case, phase contrast is well conditioned, first of all, by microheterogeneity of elastic properties of the investigated surfaces. In this study an attempt was also made to correlate the results of phase imaging with that of the farce spectroscopy. The joint analysis of information on the surface properties obtained by the phase imaging and quantitative data measured with the force spectroscopy methods allows a better understanding of the nature of the surface micromechanical heterogeneity.

• 한국지반환경공학회 논문집
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• 제10권7호
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• pp.143-150
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• 2009

연약지반의 적정 압밀속도 및 압밀침하량 예측에 있어 유효응력, 투수계수, 압밀계수, 체적변화계수 등의 물질함수는 가장 중요한 요소로 작용한다. 본 연구에서는 수평배수 조건에서의 압밀 물질함수 산정을 위한 개량형 수평배수 압밀시험 장치를 고안하고, 이를 이용하여 고함수비 해성점토에 대한 압밀시험을 실시하였다. 시험에 이용된 시료는 상부 준설매립 지반과 하부 원지반점토로 구성된 남해안 산업단지 조성 현장에서 채취하였다. 기존의 표준압밀시험을 동시에 실시하였으며, 이 결과를 이용하여 배수조건별 간극비, 유효응력, 투수계수, 압밀계수, 체적변화계수 등을 분석하였다. 압밀 물질함수는 Stark(2005)이 제안한 소성지수 포함의 회귀분석 방정식 형태로 표현되었으며, 이를 통해 투수성에 대한 이방성 특성을 산정할 수 있었다.

• The Journal of Asian Finance, Economics and Business
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• 제5권4호
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• pp.73-83
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• 2018

The purpose of this paper is to examine the relationship between regional financial development and corporate investment efficiency as well as the relationship between firm-level characteristics and corporate investment efficiency. Using a large sample of A-listed companies in China from CSMAR database between 2003 and 2016, this paper explores corporate investment efficiency and its influencing factors in emerging market on the basis of heterogeneous stochastic frontier model. The results show that: (1) the average investment efficiency of Chinese listed companies is 74.5%, and the investment efficiency of large enterprises, state-owned enterprises and enterprises with relatively high financial development level is significantly higher; (2) compared with average corporate investment efficiency in the year 2003, the investment efficiency of different types of enterprises in 2016 is significantly higher, and the gap is gradually widening; (3) enterprise heterogeneity namely firm size, nature of property right, and institutional environment reflected by the level of regional financial development indirectly affects corporate investment efficiency by influencing the financing constraints and uncertainty. The findings suggest that to improve corporate investment efficiency in emerging market, financial market should be accelerated, regional balance should be restored and the differences among regions, industries and differences between public and private sectors should be eliminated.